Yin-Che Lu, Chen-Yu Chiang, Yu-Wei Hsu, Chun-Jung Chen, Wen-Ying Chen, Ching-Chi Tseng, Lie-Hua Deng, Shih-Pin Chen, Yu-Hsiang Kuan
Cyclizine, an over-the-counter and prescription antihistamine, finds widespread application in the prevention and treatment of motion sickness, encompassing symptoms such as nausea, vomiting, dizziness, along with its effectiveness in managing vertigo. However, the overuse or misuse of cyclizine may lead to hallucinations, confusion, tachycardia, and hypertension. The molecular mechanisms underlying cyclizine-induced cytotoxicity and apoptosis remain unclear. During the 24 h incubation duration, RAW264...
February 5, 2024: Environmental Toxicology