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https://www.readbyqxmd.com/read/28605066/bulk-single-crystal-like-structural-and-magnetic-characteristics-of-epitaxial-spinel-ferrite-thin-films-with-elimination-of-antiphase-boundaries
#1
Amit V Singh, Behrouz Khodadadi, Jamileh Beik Mohammadi, Sahar Keshavarz, Tim Mewes, Devendra Singh Negi, Ranjan Datta, Zbigniew Galazka, Reinhard Uecker, Arunava Gupta
Spinel ferrite NiFe2 O4 thin films have been grown on three isostructural substrates, MgAl2 O4 , MgGa2 O4 , and CoGa2 O4 using pulsed laser deposition. These substrates have lattice mismatches of 3.1%, 0.8%, and 0.2%, respectively, with NiFe2 O4 . As expected, the films grown on MgAl2 O4 substrate show the presence of the antiphase boundary defects. However, no antiphase boundaries (APBs) are observed for films grown on near-lattice-matched substrates MgGa2 O4 and CoGa2 O4 . This demonstrates that by using isostructural and lattice-matched substrates, the formation of APBs can be avoided in NiFe2 O4 thin films...
June 12, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28589426/clinical-condition-and-comorbidity-as-determinants-for-blood-culture-positivity-in-patients-with-skin-and-soft-tissue-infections
#2
F V van Daalen, M C Kallen, C M A van den Bosch, M E J L Hulscher, S E Geerlings, J M Prins
The utility of performing blood cultures in patients with a suspected skin infection is debated. We investigated the association between blood culture positivity rates and patients' clinical condition, including acute disease severity and comorbidity. We performed a retrospective study, including patients with cellulitis and wound infection who had been enrolled in three Dutch multicenter studies between 2011 and 2015. Patients' acute clinical condition was assessed using the Modified Early Warning Score (MEWS; severe: MEWS ≥2) and comorbidity with the Charlson Comorbidity Index (CCI; severe: CCI ≥2)...
June 7, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28576864/lin-41-and-oma-ribonucleoprotein-complexes-mediate-a-translational-repression-to-activation-switch-controlling-oocyte-meiotic-maturation-and-the-oocyte-to-embryo-transition-in-caenorhabditis-elegans
#3
Tatsuya Tsukamoto, Micah D Gearhart, Caroline A Spike, Gabriela Huelgas-Morales, Makaela Mews, Peter R Boag, Traude H Beilharz, David Greenstein
An extended meiotic prophase is a hallmark of oogenesis. Hormonal signaling activates the CDK1/cyclin B kinase to promote oocyte meiotic maturation, which involves nuclear and cytoplasmic events. Nuclear maturation encompasses nuclear envelope breakdown, meiotic spindle assembly, and chromosome segregation. Cytoplasmic maturation involves major changes in oocyte protein translation and cytoplasmic organelles and is poorly understood. In the nematode Caenorhabditis elegans, sperm release the major sperm protein (MSP) hormone to promote oocyte growth and meiotic maturation...
June 1, 2017: Genetics
https://www.readbyqxmd.com/read/28576155/the-louvre-laboratory-state-of-the-art-ultrafast-ultraviolet-spectroscopies-for-molecular-and-materials-science
#4
Malte Oppermann, Natalia S Nagornova, Aurelio Oriana, Edoardo Baldini, Lars Mewes, Benjamin Bauer, Tania Palmieri, Thomas Rossi, Frank van Mourik, Majed Chergui
We describe the facilities for ultraviolet studies in the femtosecond to nanosecond time domain. These facilities consist of: i) a set-up for deep-ultraviolet spectroscopy in the 260-380 nm range in both pump and probe pulses for transient absorption/reflectivity or two-dimensional spectroscopy studies; ii) a set-up for ultrafast fluorescence measurements with detection down to 300 nm. The capabilities of these set-ups are demonstrated by examples on molecular systems, biosystems, nanoparticles and solid materials...
May 31, 2017: Chimia
https://www.readbyqxmd.com/read/28562591/acetyl-coa-synthetase-regulates-histone-acetylation-and-hippocampal-memory
#5
Philipp Mews, Greg Donahue, Adam M Drake, Vincent Luczak, Ted Abel, Shelley L Berger
Metabolic production of acetyl coenzyme A (acetyl-CoA) is linked to histone acetylation and gene regulation, but the precise mechanisms of this process are largely unknown. Here we show that the metabolic enzyme acetyl-CoA synthetase 2 (ACSS2) directly regulates histone acetylation in neurons and spatial memory in mammals. In a neuronal cell culture model, ACSS2 increases in the nuclei of differentiating neurons and localizes to upregulated neuronal genes near sites of elevated histone acetylation. A decrease in ACSS2 lowers nuclear acetyl-CoA levels, histone acetylation, and responsive expression of the cohort of neuronal genes...
June 15, 2017: Nature
https://www.readbyqxmd.com/read/28550472/salt-induced-na-k-atpase-%C3%AE-%C3%AE-expression-involves-soluble-adenylyl-cyclase-in-endothelial-cells
#6
Mirja Mewes, Johanna Nedele, Katrin Schelleckes, Olga Bondareva, Malte Lenders, Kristina Kusche-Vihrog, Hans-Joachim Schnittler, Stefan-Martin Brand, Boris Schmitz, Eva Brand
High dietary salt intake may lead to vascular stiffness, which predicts cardiovascular diseases such as heart failure, and myocardial and cerebral infarctions as well as renal impairment. The vascular endothelium is a primary target for deleterious salt effects leading to dysfunction and endothelial stiffness. We hypothesize that the Ca(2+)- and bicarbonate-activated soluble adenylyl cyclase (sAC) contributes to Na(+)/K(+)-ATPase expression regulation in vascular endothelial cells and is an important regulator of endothelial stiffness...
May 26, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/28541279/do-the-data-really-support-ordering-fragile-x-testing-as-a-first-tier-test-without-clinical-features
#7
Veronique Weinstein, Pranoot Tanpaiboon, Kimberly A Chapman, Nicholas Ah Mew, Sean Hofherr
PurposeCurrent guidelines recommend first-tier chromosome microarray analysis (CMA) and fragile X syndrome (FX) testing for males with isolated intellectual disabilities/learning delay (ID/LD) and autism spectrum disorders (ASDs).MethodsMales in our clinic with ID/LD or ASD (310) were analyzed for positive results from CMA and/or FX testing.ResultsCMA detected abnormalities in 29% of males with ID/LD and only 9% of males with ASD (including variants of uncertain significance and absence of heterozygosity). When males with ID/LD were tested for FX, the detection rate was 2...
May 25, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28535450/the-global-burden-of-fatal-self-poisoning-with-pesticides-2006-15-systematic-review
#8
REVIEW
Emma J Mew, Prianka Padmanathan, Flemming Konradsen, Michael Eddleston, Shu-Sen Chang, Michael R Phillips, David Gunnell
BACKGROUND: Agricultural pesticide poisoning is a major contributor to the global burden of suicide. Over the last decade there has been a marked decrease in the incidence of suicide worldwide. It is unclear whether pesticide poisoning still plays a significant role in the global incidence of suicide. METHODS: WHO method-specific suicide data were supplemented by a systematic review of the literature between 2006 and 2015, including searches of thirteen electronic databases and Google, citation searching and a review of reference lists and personal collections...
May 12, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28526863/potential-of-pedot-pss-as-a-hole-selective-front-contact-for-silicon-heterojunction-solar-cells
#9
Sara Jäckle, Martin Liebhaber, Clemens Gersmann, Mathias Mews, Klaus Jäger, Silke Christiansen, Klaus Lips
We show that the highly conductive polymer poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) can successfully be applied as a hole selective front contact in silicon heterojunction (SHJ) solar cells. In combination with a superior electron selective heterojunction back contact based on amorphous silicon (a-Si), mono-crystalline n-type silicon (c-Si) solar cells reach power conversion efficiencies up to 14.8% and high open-circuit voltages exceeding 660 mV. Since in the PEDOT:PSS/c-Si/a-Si solar cell the inferior hybrid junction is determining the electrical device performance we are capable of assessing the recombination velocity (v I ) at the PEDOT:PSS/c-Si interface...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28515604/development-and-psychometric-evaluation-of-the-pre-hospital-medical-emergencies-early-warning-scale
#10
Abbasali Ebrahimian, Gholamreza Masoumi, Roohangiz Jamshidi-Orak, Hesam Seyedin
INTRODUCTION: The number of requests for emergency medical services (EMSs) has increased during the past decade. However, most of the transports are not essential. Therefore, it seems crucial to develop an instrument to help EMS staff accurately identify patients who need pre-hospital care and transportation. The aim of this study was to develop and evaluate the psychometric properties of the Pre-hospital Medical Emergencies Early Warning Scale (Pre-MEWS). MATERIALS AND METHODS: This mixed-method study was conducted in two phases...
April 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28494638/an-environmental-scan-of-emergency-response-systems-and-services-in-remote-first-nations-communities-in-northern-ontario
#11
E J Mew, S D Ritchie, D VanderBurgh, J L Beardy, J Gordon, M Fortune, S Mamakwa, A M Orkin
BACKGROUND: Approximately 24,000 Ontarians live in remote Indigenous communities with no road access. These communities are a subset of Nishnawbe Aski Nation (NAN), a political grouping of 49 First Nations communities in Northern Ontario, Canada. Limited information is available regarding the status of emergency care in these communities. OBJECTIVE: We aimed to understand emergency response systems, services, and training in remote NAN communities. DESIGN: We used an environmental scan approach to compile information from multiple sources including community-based participatory research...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28490566/a-retrospective-cohort-study-of-the-utility-of-the-modified-early-warning-score-for-interfacility-transfer-of-patients-with-traumatic-injury
#12
Kristin Salottolo, Matthew Carrick, Jacob Johnson, Mark Gamber, David Bar-Or
OBJECTIVE: The modified early warning score (MEWS) is a 'track and trigger' score using routine physiological vital signs. The objective is to determine if the pretransfer MEWS can be used for predicting outcomes in trauma patients requiring interfacility transfer to higher levels of care. DESIGN, SETTING AND PARTICIPANTS: Retrospective study of consecutively transferred trauma patients into a level-II trauma centre from 2013 to 2014. INTERVENTIONS: None...
May 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28489388/ultrathin-and-highly-passivating-silica-shells-for-luminescent-and-water-soluble-cdse-cds-nanorods
#13
Xiao Tang, Elvira Kröger, Andreas Nielsen, Christian Strelow, Alf Mews, Tobias Kipp
Microemulsion (water-in-oil) methods enable the encapsulation of individual nanoparticles into SiO2 spheres. The major drawbacks of this method, when applied for silica encapsulation of anisotropic nanorods (NRs), are spatially unequal silica growth and long reaction times (24 h at least). In this work, various tetraalkoxysilanes [tetramethyl orthosilicate (TMOS), tetraethyl orthosilicate (TEOS), and tetrapropyl orthosilicate (TPOS)] with different alkyl-chain lengths were used as silica precursors in attempt to tune the silanization behavior of CdSe/CdS NRs in a microemulsion system...
May 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28484790/lateral-meniscus-posterior-root-tear-contributes-to-anterolateral-rotational-instability-and-meniscus-extrusion-in-anterior-cruciate-ligament-injured-patients
#14
Takao Minami, Takeshi Muneta, Ichiro Sekiya, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Hiroki Katagiri, Koji Otabe, Toshiyuki Ohara, Mai Katakura, Hideyuki Koga
PURPOSE: The purposes of this study were to investigate (1) meniscus status and clinical findings in anterior cruciate ligament (ACL)-injured patients to clarify associations between the meniscus posterior root tear (PRT) and knee instability, and (2) magnetic resonance imaging (MRI) findings of the PRT to clarify sensitivity and specificity of MRI and prevalence of meniscus extrusion. METHODS: Three hundred and seventeen patients with primary ACL reconstruction were included...
May 8, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28463183/personalized-risk-scoring-for-critical-care-prognosis-using-mixtures-of-gaussian-processes
#15
Ahmed M Alaa, Jinsung Yoon, Scott Hu, Mihaela van der Schaar
In this paper, we develop a personalized real-time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs; the proposed risk scoring system ensures timely intensive care unit (ICU) admissions for clinically deteriorating patients. METHODS: The risk scoring system is based on the idea of sequential hypothesis testing under an uncertain time horizon. The system learns a set of latent patient subtypes from the offline electronic health record data, and trains a mixture of Gaussian Process (GP) experts, where each expert models the physiological data streams associated with a specific patient subtype...
April 27, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28445859/a-risk-scoring-model-based-on-vital-signs-and-laboratory-data-predicting-transfer-to-the-intensive-care-unit-of-patients-admitted-to-gastroenterology-wards
#16
Won-Young Kim, Jinmi Lee, Ju-Ry Lee, Youn Kyung Jung, Hwa Jung Kim, Jin Won Huh, Chae-Man Lim, Younsuck Koh, Sang-Bum Hong
PURPOSE: To compare the ability of a score based on vital signs and laboratory data with that of the modified early warning score (MEWS) to predict ICU transfer of patients with gastrointestinal disorders. MATERIALS AND METHODS: Consecutive events triggering medical emergency team activation in adult patients admitted to the gastroenterology wards of the Asan Medical Center were reviewed. Binary logistic regression was used to identify factors predicting transfer to the ICU...
April 19, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28403756/first-confirmed-case-of-transfusion-transmitted-hepatitis-e-in-australia
#17
Veronica C Hoad, Tristan Gibbs, Madhur Ravikumara, Monica Nash, Avram Levy, Samantha L Tracy, Catherine Mews, Zofia Perkowska-Guse, Helen M Faddy, Scott Bowden
No abstract text is available yet for this article.
April 17, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28374682/biofabricated-soft-network-composites-for-cartilage-tissue-engineering
#18
Onur Bas, Elena De-Juan-Pardo, Christoph Meinert, Davide D'Angella, Jeremy Baldwin, Laura Bray, R Wellard, Stefan Kollmannsberger, Ernst Rank, Carsten Werner, Travis Klein, Isabelle Catelas, Dietmar Werner Hutmacher
Articular cartilage from a material science point of view is a soft network composite that plays a critical role in load-bearing joints during dynamic loading. Its composite structure, consisting of a collagen fiber network and a hydrated proteoglycan matrix, gives rise to the complex mechanical properties of the tissue including viscoelasticity and stress relaxation. Melt Electrospinning Writing (MEW) allows the design and fabrication of medical grade polycaprolactone (mPCL) fibrous networks for the reinforcement of soft hydrogel matrices for cartilage tissue engineering...
April 4, 2017: Biofabrication
https://www.readbyqxmd.com/read/28355387/effects-of-soil-and-space-on-the-woody-species-composition-and-vegetation-structure-of-three-cerrado-phytophysiognomies-in-the-cerrado-amazon-transition
#19
L Maracahipes-Santos, E Lenza, J O Santos, H A Mews, B Oliveira
The Cerrado Biome is considered one of the world's biodiversity hotspots because of its rich biodiversity, the high level of endemism and the increasing threat. The Cerrado is composed by a mosaic of different vegetation types, including physiognomies that vary from grasslands (campo limpo) to savannas (typical cerrado or cerrado sensu stricto) and cerrado woodlands (cerradão). However, the factors that determine the composition of the Cerrado's flora and the structure of the physiognomies that compose this biome are still poorly understood...
March 16, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/28351349/development-and-validation-of-the-efficacy-safety-score-ess-a-novel-tool-for-postoperative-patient-management
#20
Erlend Skraastad, Johan Ræder, Vegard Dahl, Lars J Bjertnæs, Vladimir Kuklin
BACKGROUND: Several reports have shown that postoperative monitoring of general safety and quality issues, including pain treatment, after discharge from recovery is often non-systematic and inadequate. We suggest a new score with assessment of key recovery parameters, as a supportive tool for postoperative care and a call-out algorithm for need of extra help. The aim of this investigation was to validate the score. METHODS: After suggesting a prototype score from a pilot study in 182 postoperative patients, we performed a Delphi process by using international experts to create consensus on the final score contents and called the revised tool the Efficacy Safety Score (ESS)...
March 28, 2017: BMC Anesthesiology
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