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Type 1 diabetes in adolescent

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https://www.readbyqxmd.com/read/29049584/association-of-insulin-pump-therapy-vs-insulin-injection-therapy-with-severe-hypoglycemia-ketoacidosis-and-glycemic-control-among-children-adolescents-and-young-adults-with-type-1-diabetes
#1
Beate Karges, Anke Schwandt, Bettina Heidtmann, Olga Kordonouri, Elisabeth Binder, Ulrike Schierloh, Claudia Boettcher, Thomas Kapellen, Joachim Rosenbauer, Reinhard W Holl
Importance: Insulin pump therapy may improve metabolic control in young patients with type 1 diabetes, but the association with short-term diabetes complications is unclear. Objective: To determine whether rates of severe hypoglycemia and diabetic ketoacidosis are lower with insulin pump therapy compared with insulin injection therapy in children, adolescents, and young adults with type 1 diabetes. Design, Setting, and Participants: Population-based cohort study conducted between January 2011 and December 2015 in 446 diabetes centers participating in the Diabetes Prospective Follow-up Initiative in Germany, Austria, and Luxembourg...
October 10, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29048542/adolescent-information-management-and-parental-knowledge-in-non-latino-white-and-latino-youth-managing-type-1-diabetes
#2
Christy Tucker, Deborah J Wiebe, Alexandra Main, Alyssa G Lee, Perrin C White
The objective of this study is to examine associations between adolescents' regulation of information about their type 1 diabetes (adolescent disclosure, secrecy), parental knowledge about their adolescent's diabetes management, diabetes outcomes (adherence, HbA1c), and depressive symptoms in Non-Latino White and Latino families. In all, 118 adolescents (56 = Latino, 62 = Non-Latino White) completed surveys of disclosure to and secrecy from parents, parental knowledge of adolescent diabetes management, adherence, and depressive symptoms, and mothers completed measures of maternal knowledge and adolescent adherence...
August 31, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29048478/the-role-of-authoritative-parenting-in-adolescent-type-1-diabetes-management
#3
Zach Radcliff, Patrick Weaver, Rusan Chen, Randi Streisand, Clarissa Holmes
Adolescents with Type 1 diabetes are at risk for poorer adherence, lower quality of life (QOL), and poorer glycemic control (HbA1c). Authoritative parenting (AP) along with youth adherence and QOL was hypothesized to relate to better HbA1c. Parent-youth dyads ( N  = 257) completed baseline measures of adherence and QOL. Youth completed an AP questionnaire, and HbA1c samples were evaluated. Structural equation modeling determined relations among AP, adherence, QOL, and glycemic control. AP indirectly linked to better HbA1c (β = -...
August 17, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29039345/validation-of-transition-readiness-assessment-questionaire-in-turkish-adolescents-with-diabetes
#4
Evrim Kızıler, Dilek Yıldız, Berna Eren Fidancı
BACKGROUND: Today, more than 90% of adolescents with chronic conditions are surviving into adulthood and move pediatric to adult care with their chronic illness. It is important to gain autonomy and ensure readiness for adolescents/ young adults to use the adult health care system prior to the transfer of care. However, the lack of the transition readiness assessment tool which is validated, patient-centered and appropriate to developmental differences in pediatric care is seen a major obstacle for transition of care from pediatric to adult services...
October 17, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/29039272/editorial-precursors-of-cardiovascular-disease-in-adolescent-type-1-diabetes
#5
EDITORIAL
Robert P Hoffman
No abstract text is available yet for this article.
2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29037929/severe-sepsis-and-acute-myocardial-dysfunction-in-an-adolescent-with-chlamydia-trachomatis-pelvic-inflammatory-disease-a-case-report
#6
Ashley M Morgan, R Claire Roden, Steven C Matson, Grant M Wallace, Hannah L H Lange, Andrea E Bonny
BACKGROUND: Although generally asymptomatic, severe Chlamydia trachomatis (C. trachomatis) infections have been documented. C. trachomatis has been associated with both myocarditis and sepsis. CASE: A 19-year-old female with type 1 diabetes mellitus developed sudden-onset mental status change and shock after resolution of diabetic ketoacidosis. Abdominal and pelvic imaging demonstrated uterine and adnexal inflammation, and pelvic exam confirmed a diagnosis of pelvic inflammatory disease...
October 13, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29034607/complete-loss-of-insulin-secretion-capacity-in-type-1a-diabetic-patients-during-long-term-follow-up
#7
Sae Uno, Akihisa Imagawa, Junji Kozawa, Kenji Fukui, Hiromi Iwahashi, Iichiro Shimomura
AIM/INTRODUCTION: The patients with type 1 diabetes are classified into three subtypes: acute-onset, fulminant, and slowly progressive in Japan. Acute-onset type 1 diabetes would be equivalent to type 1A diabetes, the typical type 1 diabetes in Western countries. The insulin secretion capacity in Japanese subjects with long-standing type 1A diabetes is unclear. The aim of this study is to clarify the course of endogenous insulin secretion during long-term follow-up and factors associated with residual insulin secretion in patients with acute-onset type 1 diabetes (autoimmune)...
October 16, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29027597/lipoprotein-associated-phospholipase-a2-activity-in-obese-adolescents-with-and-without-type-2-diabetes
#8
Julia Seyfarth, Thomas Reinehr, Annika Hoyer, Christina Reinauer, Christina Bächle, Beate Karges, Ertan Mayatepek, Michael Roden, Sabine E Hofer, Susanna Wiegand, Joachim Woelfle, Wieland Kiess, Joachim Rosenbauer, Reinhard W Holl, Thomas Meissner
Lipoprotein-associated phospholipase A2 (Lp-PLA2) was identified as a strong predictor for cardiovascular events. Furthermore, it is highly associated with obesity. The role of Lp-PLA2 in diabetes mellitus is controversial and analyses, especially in adolescents with type 2 diabetes (T2D), are missing. Therefore, we compared Lp-PLA2 activity between two obese age-, sex-, and BMI-matched cohorts of adolescents with and without T2D. Relationships between Lp-PLA2 activity and age, BMI, hemoglobin A1c, lipids, and adipokines were evaluated...
October 13, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/29026922/erratum-to-innovative-technology-shows-impact-of-glycaemic-control-on-peripheral-retinal-vessels-in-adolescents-with-type-1-diabetes
#9
Valli Velayutham, Paul Z Benitez-Aguirre, Maria E Craig, Gerald Liew, Tien Y Wong, Alicia J Jenkins, Kim C Donaghue
No abstract text is available yet for this article.
October 1, 2017: Diabetologia
https://www.readbyqxmd.com/read/29025203/impact-of-targeted-education-on-managing-warning-and-error-signals-by-children-and-adolescents-with-type-1-diabetes-using-the-accu-chek-combo-insulin-pump-system
#10
Asma Deeb, Nabras Al Qahtani, Amal Al Ali, Mariette Akle
PURPOSE: Insulin pumps are widely used in diabetes. They are equipped with safety alarms to alert users. Pump manuals contain alarm codes and how to troubleshoot them. However, these manuals are lengthy and difficult to use, particularly in emergencies. We aim to assess the impact of targeted education on warnings and errors in improving competency to troubleshoot the alarms. METHODS: Twenty-one patients, with a median age of 13, were recruited over a 5-month period...
September 2017: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/29023255/adolescent-perceptions-of-peer-responses-to-diabetes-self-management-a-qualitative-study
#11
Pei-Yun Yang, Meei-Fang Lou, Angela Shin-Yu Lien, Bih-Shya Gau
BACKGROUND: Type 1 diabetes (T1D) is more prevalent in adolescents than in adults, and the self-management of insulin-dependent diabetes is complex. T1D requires injections of insulin, self-management of blood testing, regular physical activity, and diet monitoring, which are challenging for growing and developing adolescents. Adolescents are often more concerned with how they are perceived by their peers than how they perceive themselves. Positive peer responses influence the self-care management of adolescents with T1D in school settings...
October 12, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29017892/muscle-functions-and-bone-strength-are-impaired-in-adolescents-with-type-1-diabetes
#12
Klara Maratova, Ondrej Soucek, Jana Matyskova, Zdenek Hlavka, Lenka Petruzelkova, Barbora Obermannova, Stepanka Pruhova, Stanislava Kolouskova, Zdenek Sumnik
BACKGROUND: Sarcopenia and osteoporosis are among the late complications of type 1 diabetes (T1D) in adults. Whether and to what extent musculoskeletal impairment is present in childhood and adolescence has yet to be determined. The aim of this study was to assess volumetric bone mineral density (BMD) and dynamic muscle function in adolescents with T1D and to assess the clinical and biochemical predictors of their musculoskeletal system. METHODS: Ninety-five children and adolescents (59 boys and 36 girls, mean age 16...
October 7, 2017: Bone
https://www.readbyqxmd.com/read/29017015/a-twelve-week-lifestyle-program-to-improve-cardiometabolic-behavioral-and-psychological-health-in-hispanic-children-and-adolescents
#13
Sami Yli-Piipari, Alison Berg, Emma M Laing, Diane L Hartzell, Kenneth O Parris, Jon Udwadia, Richard D Lewis
OBJECTIVES: To examine the effectiveness of a 12-week lifestyle program on cardiometabolic, behavioral, and psychological outcomes among overweight Hispanic children and adolescents. DESIGN: A case series study with pre- and post-test analyses. Subjects/Settings/Location: A convenience sample of high-risk pediatric primary care patients (n = 22; 6 girls, 16 boys; M age = 11.73 ± 1.39 years) and their guardians in the Southeast United States. INTERVENTION: Twice per week 60 min (total of 24 h) of moderate-to-vigorous intensity boxing exercise training, 12 h of nutrition education for guardians, and a 30-min pediatrician appointment...
October 10, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28993721/team-clinic-an-innovative-group-care-model-for-youth-with-type-1-diabetes-engaging-patients-and-meeting-educational-needs
#14
Cari Berget, Jennifer Lindwall, Jacqueline J Shea, Georgeanna J Klingensmith, Barbara J Anderson, Cindy Cain, Jennifer K Raymond
The purpose of this pilot was to implement an innovative group care model, "Team Clinic", for adolescents with type 1 diabetes and assess patient and provider perspectives. Ninety-one intervention patients and 87 controls were enrolled. Ninety-six percent of intervention adolescents endorsed increased support and perceived connecting with peers as important. The medical providers and staff also provided positive feedback stating Team Clinic allowed more creativity in education and higher quality of care. Team Clinic may be a promising model to engage adolescents and incorporate education and support into clinic visits in a format valued by patients and providers...
June 2017: Journal for Nurse Practitioners: JNP
https://www.readbyqxmd.com/read/28989569/clinical-profile-of-diabetes-at-diagnosis-among-children-and-adolescents-at-an-endocrine-clinic-in-ghana
#15
Emmanuel Ameyaw, Serwah B Asafo-Agyei, Sumithira Thavapalan, Angela C Middlehurst, Graham D Ogle
AIM: To determine the clinical features of diabetes in children and adolescents in Ghana. METHODS: Retrospective review of clinical features of all children and adolescents with new-onset diabetes seen at the paediatric endocrinology clinic of Komfo Anokye Teaching Hospital in Kumasi, from February 2012 to Auguest 2016. RESULTS: One hundred and six subjects presented with diabetes. Ninety (84.9%) were diagnosed by clinical features and family history as type 1, and 16 (15...
September 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28971223/differential-effects-of-age-and-sex-on-insulin-sensitivity-and-body-composition-in-adolescent-offspring-of-women-with-type-1-diabetes-results-from-the-epicom-study
#16
Zuzana Lohse, Sine Knorr, Birgitte Bytoft, Tine D Clausen, Rikke B Jensen, Peter Oturai, Henning Beck-Nielsen, Claus H Gravholt, Peter Damm, Kurt Højlund, Dorte M Jensen
AIMS/HYPOTHESIS: The aim of this study was to investigate the influence of age and sex on insulin sensitivity and insulin secretion in the adolescent offspring of women with type 1 diabetes, compared with the background population. METHODS: This was a prospective nationwide follow-up study (Epigenetic, Genetic and Environmental Effects on Growth, Cognitive Functions and Metabolism in Offspring of Women with Type 1 Diabetes [EPICOM]) in a Danish population. We examined 278 offspring of women with type 1 diabetes from the Danish Diabetes Association Register born during 1993-1999 (index offspring) and 303 control offspring, identified through the Danish Central Office of Civil Registration and matched to the index offspring with respect to date of birth, sex and postal code...
October 3, 2017: Diabetologia
https://www.readbyqxmd.com/read/28952380/in-silico-modeling-of-minimal-effective-insulin-doses-using-the-uva-padova-type-1-diabetes-simulator
#17
Enrique Campos-Náñez, Jennifer E Layne, Howard C Zisser
BACKGROUND: The objective of this study was to identify the minimum basal insulin infusion rates and bolus insulin doses that would result in clinically relevant changes in blood glucose levels in the most insulin sensitive subjects with type 1 diabetes. METHODS: The UVA/PADOVA Type 1 Diabetes Simulator in silico population of children, adolescents, and adults was administered a basal insulin infusion rate to maintain blood glucose concentrations at 120 mg/dL (6...
September 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28948172/incidence-and-mortality-rates-and-clinical-characteristics-of-type-1-diabetes-among-children-and-young-adults-in-cochabamba-bolivia
#18
Elizabeth Duarte Gómez, Gabriel Andrew Gregory, Miriam Castrati Nostas, Angela Christine Middlehurst, Alicia Josephine Jenkins, Graham David Ogle
OBJECTIVES: To determine incidence, mortality, and clinical status of youth with diabetes at the Centro Vivir con Diabetes, Cochabamba, Bolivia, with support from International Diabetes Federation Life for a Child Program. METHODS: Incidence/mortality data analysis of all cases (<25 year (y)) diagnosed January 2005-February 2017 and cross-sectional data (December 2015). RESULTS: Over 12.2 years, 144 cases with type 1 diabetes (T1D) were diagnosed; 43...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28943512/prevalence-of-znt8-antibody-in-turkish-children-and-adolescents-with-new-onset-type-1-diabetes
#19
Selin Elmaoğulları, Seyit Ahmet Uçaktürk, Şehri Elbeg, Esra Döğer, Meltem Tayfun, Fatih Gürbüz, Aysun Bideci
OBJECTIVE: Zinc transporter 8 protein (ZnT8) is a transmembranic protein organizing the zinc transfer to insulin vesicles. Antibodies formed against ZnT8 (ZnT8A) are regarded as an independent autoimmunity demonstrator in type 1 diabetes (T1D) diagnosis Investigation of ZnT8ab prevalence in Turkish children with new onset T1D was planned in this study. METHODS: 84 patients between 1-18 years of age diagnosed with T1D between February 2015- March 2016 and the control group consisting of 50 healthy children without any autoimmune diseases were included in the study...
September 25, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28940941/childhood-body-mass-index-in-relation-to-subsequent-risk-of-type-1-diabetes-a-danish-cohort-study
#20
Julie C Antvorskov, Lise Aunsholt, Karsten Buschard, Michael Gamborg, Kurt Kristensen, Jesper Johannesen, Thorkild I A Sørensen, Jannet Svensson
The incidence of type 1 diabetes (T1D) is increasing, and obesity may be a contributing factor by increasing the risk and accelerating the onset. We investigated the relation between childhood body mass index z-scores (BMIz) and the later risk of T1D, including association with age at onset of T1D. The study included 238 cases and 10 147 controls selected from the Copenhagen School Health Record Register (CSHRR). Cases of T1D were identified in the Danish Registry of Childhood and Adolescent Diabetes and 2 regional studies and linked to CSHRR...
September 22, 2017: Pediatric Diabetes
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