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Knee Osteoarthritis

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https://www.readbyqxmd.com/read/28222422/impact-of-diet-and-or-exercise-intervention-on-infrapatellar-fat-pad-morphology-secondary-analysis-from-the-intensive-diet-and-exercise-for-arthritis-idea-trial
#1
Aarón Leonardo Pogacnik Murillo, Felix Eckstein, Wolfgang Wirth, Daniel Beavers, Richard F Loeser, Barbara J Nicklas, Shannon L Mihalko, Gary D Miller, David J Hunter, Stephen P Messier
OBJECTIVES: The infrapatellar fat pad (IPFP) represents intra-articular adipose tissue that may contribute to intra-articular inflammation and pain by secretion of proinflammatory cytokines. Here we examined the impact of weight loss by diet and/or exercise interventions on the IPFP volume. METHODS: Intensive Diet and Exercise for Arthritis (IDEA) was a single-blinded, single-center, 18-month, prospective, randomized controlled trial that enrolled 454 overweight and obese older adults with knee pain and radiographic osteoarthritis...
February 22, 2017: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/28222057/effects-of-toe-in-and-wider-step-width-in-stair-ascent-with-different-knee-alignments
#2
Hunter J Bennett, Songning Zhang, Guangping Shen, Joshua T Weinhandl, Max R Paquette, Jeffrey Reinbolt, Dawn P Coe
PURPOSE: Toe-in (TI) and toe-in with wider step width (TIW) gait modifications have successfully reduced the internal peak knee adduction moment (KAM) during level walking and stair ascent tasks, respectively, for healthy and knee osteoarthritis populations. However, the concurrent effects of these modifications have not previously been combined to reduce both the first and the second peak KAM during stair ascent or tested among the different knee alignment groups. Therefore, the purpose of this study was to examine effects of TI and TIW gait modifications on knee biomechanics during stair ascent in individuals with varus, neutral, and valgus knee alignments...
March 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28220190/open-wedge-high-tibial-osteotomy-versus-unicompartmental-knee-arthroplasty-no-difference-in-progression-of-patellofemoral-joint-arthritis
#3
Kwang-Jun Oh, Young Chan Kim, Jong Seong Lee, Yong Suk Chang, Gautam M Shetty, Kyung Wook Nha
PURPOSE: The purpose of this retrospective comparative study was to evaluate and compare, radiographically and clinically, progression of osteoarthritis (OA) in the patellofemoral (PF) compartment after open-wedge high tibial osteotomy (OWHTO), and unicompartmental knee arthroplasty (UKA) over a minimum follow-up of 5 years. METHODS: In this study, 42 knees in an OWHTO group were compared with 59 knees in a UKA group in terms of radiographic parameters, such as the grading system for OA progression in the PF compartment, and clinical parameters, such as the PF pain and function scores over a minimum follow-up of 5 years...
February 20, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28219307/comparative-evaluation-of-posterior-cruciate-ligament-in-total-knee-arthroplasty
#4
Yuan Ma, Wei-Jia Chen, Ryuji Nagamine
INTRODUCTION: It has been realized that for osteoarthritis (OA) knee with varus deformity, posterior cruciate ligament (PCL) release resulted in the increase of the flexion gap without significant effect on the extension gap. While the effect of release on gap angle is still obscure. On the other hand, gap distance and varus angle measured under different distraction forces suggest different patterns. OBJECTIVES: In the current study, mechanical gap balance in displacement and angular alternation of extension and flexion gaps will be evaluated, with PCL fully retained or resected under different distracting forces in varus knees...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28219088/single-bundle-versus-double-bundle-anterior-cruciate-ligament-reconstruction-a-prospective-randomized-controlled-trial-with-6-year-follow-up
#5
Paolo Adravanti, Francesco Dini, Laura de Girolamo, Massimo Cattani, Michele Attilio Rosa
Single-bundle (SB) anterior cruciate ligament (ACL) reconstruction is increasingly used in a large number of patients and it allows obtaining very good clinical and subjective results; however, functional tests show a persistent rotational instability. Biomechanical studies seem to indicate that double-bundle (DB) ACL reconstruction allows to obtain increased anterior and rotational stability compared with SB. The aim of this prospective randomized controlled study was to compare the clinical outcome and the possible osteoarthritic evolution of patients treated either with a SB (freehand transtibial femoral tunnel) or with a DB technique (outside-in for posterolateral femoral tunnel/inside-out for anteromedial femoral tunnel) at a final follow-up of 6 years...
February 20, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28218341/influence-of-hip-and-knee-osteoarthritis-on-dynamic-postural-control-parameters-among-older-fallers
#6
Sumaiyah Mat, Chin Teck Ng, Maw Pin Tan
OBJECTIVE: To compare the relationship between postural control and knee and hip osteoarthritis in older adults with and without a history of falls. METHODS: Fallers were those with ≥ 2 falls or 1 injurious fall over 12 months. Non-fallers were volunteers with no falls in the past year. Radiological evidence of osteoarthritis with no reported symptoms was considered "asymptomatic osteoarthritis", while "symptomatic osteoarthritis" was defined as radiographic osteoarthritis with pain or stiffness...
February 16, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28217895/serum-urate-levels-predict-joint-space-narrowing-in-non-gout-patients-with-medial-knee-osteoarthritis
#7
Svetlana Krasnokutsky, Charles Oshinsky, Mukundan Attur, Sisi Ma, Hua Zhou, Fangfei Zheng, Meng Chen, Jyoti Patel, Jonathan Samuels, Virginia C Pike, Ravinder Regatte, Jenny Bencardino, Leon Rybak, Steven Abramson, Michael H Pillinger
OBJECTIVE: OA pathogenesis includes both mechanical and inflammatory features. Studies have implicated synovial fluid urate (UA) as a potential OA biomarker, possibly reflecting chondrocyte damage. Whether serum urate (sUA) levels reflect/contribute to OA is unknown. We investigated whether sUA predicts OA progression in a non-gout knee OA population. METHODS: Eighty-eight subjects with medial knee OA (BMI <33) but without gout were included. Baseline sUA was measured in previously banked serum...
February 19, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28217864/-sounds-a-bit-crazy-but-it-was-almost-more-personal-a-qualitative-study-of-patient-and-clinician-experiences-of-physical-therapist-prescribed-exercise-for-knee-osteoarthritis-via-skype%C3%A2
#8
R S Hinman, R K Nelligan, K L Bennell, C Delany
OBJECTIVES: Explore patients' and physical therapists' experience with Skype™ for exercise management of knee OA. METHODS: Qualitative study. The Donabedian model for quality assessment in health care (structure, process and outcomes) informed semi-structured individual interview questions. Twelve purposively-sampled patients with knee OA who received physical therapist-prescribed exercise over Skype™, and all therapists (n=8) who delivered the intervention, in a clinical trial were interviewed about their experiences...
February 19, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28217658/pain-management-in-total-knee-arthroplasty-efficacy-of-a-multimodal-opiate-free-protocol
#9
Gian Luigi Canata, Valentina Casale, Alfredo Chiey
PURPOSE: this study was conducted to identify the most effective method of postoperative pain management, comparing the intravenous opiate infusion protocol with the use of a single periarticular local anesthetic infiltration (LAI) in patients undergoing total knee arthroplasty (TKA) surgery. METHODS: 50 patients submitted to TKA surgery between 2013 and 2015 were divided into two groups. Buprenorphine was administered intravenously to the patients in Group A, while the Group B patients received a single periarticular LAI (ropivacaine and ketorolac) during surgery...
October 2016: Joints
https://www.readbyqxmd.com/read/28216747/complex-ao-type-c3-distal-femur-fractures-results-after-fixation-with-a-lateral-locked-plate-using-modified-swashbuckler-approach
#10
Anuj Agrawal, Vivek Kiyawat
BACKGROUND: Complex AO type C3 fractures of the distal femur are challenging injuries, fraught with complications such as malunion and stiffness. We prospectively evaluated a consecutive series of patients with complex AO type C3 distal femur fractures to determine the clinicoradiological outcome after fixation with a single locked plate using modified swashbuckler approach. MATERIALS AND METHODS: 12 patients with C3 type distal femur fractures treated with a lateral locked plate, using a modified swashbuckler approach, were included in the study...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28216313/between-group-differences-in-infra-patellar-fat-pad-size-and-signal-in-symptomatic-and-radiographic-progression-of-knee-osteoarthritis-vs-non-progressive-controls-and-healthy-knees-data-from-the-fnih-biomarkers-consortium-study-and-the-osteoarthritis-initiative
#11
Anja Ruhdorfer, Franziska Haniel, Tobias Petersohn, Jan Dörrenberg, Wolfgang Wirth, Torben Dannhauer, David J Hunter, Felix Eckstein
OBJECTIVE: To examine cross-sectional and longitudinal between-group differences of infra-patellar fat pad (IPFP) size and magnetic resonance imaging (MRI) signal from fat-suppressed intermediate-weighted images with clinically relevant symptomatic and radiographic progression of knee osteoarthritis (OA), versus healthy references. METHODS: We studied 110 case knees (KLG1-3) with radiographic (≥0.7mm loss in joint space width) and symptomatic progression (≥+9/100units on the WOMAC knee pain subscale) vs...
February 12, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28216311/meniscal-extrusion-and-bone-marrow-lesions-are-associated-with-incident-and-progressive-knee-osteoarthritis
#12
Andrew J Teichtahl, Flavia M Cicuttini, François Abram, Yuanyuan Wang, Jean-Pierre Pelletier, Pierre Dodin, Johanne Martel-Pelletier
OBJECTIVE: Whether meniscal extrusion and bone marrow lesions (BMLs) are independently associated with the risk of knee osteoarthritis (OA) is unknown. METHODS: Data was extracted from the Osteoarthritis Initiative (OAI) cohort. Participants were grouped according to the absence (Kellgren-Lawrence (KL) grade ≤ 1, n = 2120) or presence (KL ≥ 2, n = 2249) of ROA. Baseline meniscal extrusion and tibial BMLs were assessed. Tibial plateau cartilage volume was assessed at baseline and 72 months, while radiographic disease was assessed at baseline and 48 months...
February 12, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28215059/motives-for-physical-exercise-participation-as-a-basis-for-the-development-of-patient-oriented-exercise-interventions-in-osteoarthritis-a-cross-sectional-study
#13
Inga Krauss, Uwe Katzmarek, Monika A Rieger, Gorden Sudeck
BACKGROUND: Physical exercises are effective in the treatment of osteoarthritis (OA). There is consensus that exercise interventions should take into account the patient's preferences and needs in order to improve compliance to exercise regimes. One important personal factor is the patient's motivation for physical exercise. Health improvement is a relevant motive for exercise participation. Accordingly, exercise interventions primarily focus on health related needs such as strengthening and pain reduction...
February 17, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28214426/reduced-step-length-reduces-knee-joint-contact-forces-during-running-following-anterior-cruciate-ligament-reconstruction-but-does-not-alter-inter-limb-asymmetry
#14
Collin D Bowersock, Richard W Willy, Paul DeVita, John D Willson
BACKGROUND: Anterior cruciate ligament reconstruction is associated with early onset knee osteoarthritis. Running is a typical activity following this surgery, but elevated knee joint contact forces are thought to contribute to osteoarthritis degenerative processes. It is therefore clinically relevant to identify interventions to reduce contact forces during running among individuals after anterior cruciate ligament reconstruction. The primary purpose of this study was to evaluate the effect of reducing step length during running on patellofemoral and tibiofemoral joint contact forces among people with a history of anterior cruciate ligament reconstruction...
February 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28214084/il-10-and-tgf-%C3%AE-roles-in-chondroprotective-effects-of-glucosamine-in-experimental-osteoarthritis
#15
Nermien E Waly, Abeer Refaiy, Nora M Aborehab
OBJECTIVE: Osteoarthritis (OA) is a complex disease of the whole joint. Glucosamine (GlcN) treatment may have a chondroprotective effect on OA. We investigated the mechanism of action of glucosamine treatment through interleukin-10 (Il-10) and transforming growth factor β-1 (TGF β-1). METHODS: Thirty male albino rats were used. A single intraarticular (i.a.) injection of 2mg of Monosodium Iodoacetate (MIA) was injected into the knee joint of anesthetized rats...
February 11, 2017: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/28213953/the-effects-of-acl-graft-placement-on-in-vivo-knee-function-and-cartilage-thickness-distributions
#16
REVIEW
Louis E DeFrate
Injuries to the anterior cruciate ligament (ACL) frequently lead to early-onset osteoarthritis. Despite advancement in surgical techniques, ACL reconstruction has a limited ability to prevent these degenerative changes. While previous studies have investigated knee function after ACL reconstruction, in vivo investigations of the effects of graft placement on in vivo joint function and cartilage health are limited. This review presents a series of studies that used novel imaging and 3D modeling techniques to determine the in vivo placement of the ACL graft on the femur using two different ACL reconstruction techniques...
February 18, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28212675/sex-differences-in-the-association-of-skin-advanced-glycation-endproducts-with-knee-osteoarthritis-progression
#17
Charles B Eaton, Maria Sayeed, Syeda Ameernaz, Mary B Roberts, John D Maynard, Jeffrey B Driban, Timothy E McAlindon
BACKGROUND: The accumulation of advanced glycation endproducts in articular cartilage has been suggested as an etiologic factor in the development and progression of knee osteoarthritis (KOA). METHODS: We conducted a prospective cohort study of skin advanced glycation endproducts (sAGEs) measured non-invasively by skin intrinsic fluorescence and the relationship between sAGE KOA progression in 160 men and 287 women in a sub-cohort of the Osteoarthritis Initiative at a single site...
February 17, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28211301/early-results-of-patellofemoral-inlay-resurfacing-arthroplasty-using-the-hemicap-wave-prosthesis
#18
Akash Patel, Zakir Haider, Amarjit Anand, Dominic Spicer
BACKGROUND: Common surgical treatment options for isolated patellofemoral osteoarthritis include arthroscopic procedures, total knee replacement and patellofemoral replacement. The HemiCap Wave patellofemoral resurfacing prosthesis is a novel inlay design introduced in 2009 with scarce published data on its functional outcomes. We aim to prospectively evaluate early functional outcomes and complications, for patients undergoing a novel inlay resurfacing arthroplasty for isolated patellofemoral arthrosis in an independent centre...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28210788/surgical-management-of-degenerative-meniscus-lesions-the-2016-esska-meniscus-consensus
#19
Ph Beaufils, R Becker, S Kopf, M Englund, R Verdonk, M Ollivier, R Seil
PURPOSE: A degenerative meniscus lesion is a slowly developing process typically involving a horizontal cleavage in a middle-aged or older person. When the knee is symptomatic, arthroscopic partial meniscectomy has been practised for a long time with many case series reporting improved patient outcomes. Since 2002, several randomised clinical trials demonstrated no additional benefit of arthroscopic partial meniscectomy compared to non-operative treatment, sham surgery or sham arthroscopic partial meniscectomy...
February 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28210645/responsiveness-comparison-of-the-eq-5d-promis-global-health-and-vr-12-questionnaires-in-knee-arthroscopy
#20
Sameer R Oak, Gregory J Strnad, James Bena, Lutul D Farrow, Richard D Parker, Morgan H Jones, Kurt P Spindler
BACKGROUND: The EuroQol 5 dimensions questionnaire (EQ-5D), Patient-Reported Outcomes Measurement Information System (PROMIS) 10 Global Health, and Veterans RAND 12-Item Health Survey (VR-12) are generic patient-reported outcome (PRO) questionnaires that assess a patient's general health. In choosing a PRO to track general health status, it is necessary to consider which measure will be the most responsive to change after treatment. To date, no studies exist comparing responsiveness among the EQ-5D, PROMIS 10 Global Health, and the Veterans Rand 12-Item Health Survey (VR-12)...
December 2016: Orthopaedic Journal of Sports Medicine
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