Hung-Chen Chang, Xiaojun Wang, Xuchao Gu, Shuai Jiang, Wenhao Wang, Tao Wu, Maoqing Ye, Xinkai Qu, Zhijun Bao
BACKGROUND: Secretory factors linked to lymphogenesis, such as vascular endothelial growth factor C (VEGF-C), angiopoietin like protein 4 (ANGPTL4), and activin A (ACV-A), have been recognized as potential markers of chronic inflammatory status and age-related diseases. Furthermore, these factors may also be linked to frailty. The primary objective of this study was to examine the serum VEGF-C, ANGPTL4, and ACV-A levels in young individuals, healthy older individuals, and older individuals with pre-frailty and frailty, and to determine their association with pro-inflammatory factor levels...
December 11, 2023: Experimental Gerontology