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https://www.readbyqxmd.com/read/29754327/the-many-faces-of-igg4-related-disease-report-of-a-case-with-inaugural-recurrent-aortic-aneurism-ruptures-and-literature-review
#1
REVIEW
Mariana Luís, Luísa Brites, Bruno Fernandes, Diogo Jesus, Tânia Santiago, Sara Serra, João Rovisco, Lina Carvalho, José António P da Silva, Armando Malcata
Vascular involvement in IgG4-related disease (IgG4-RD), is a well-recognized feature and large vessel commitment, especially the aorta, can be the only manifestation of the disease. Being a newly recognized disease, its diagnosis and workup still represents a challenge in clinical practice. A 47-year-old-man with two aortic aneurysms ruptures, one at abdominal and the other at thoracic level, was referred to our rheumatology department. The initial analysis of the surgical specimen obtained 3 years earlier revealed a nonspecific aortitis...
May 12, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29749594/-non-aneurysmal-subarachnoid-haemorrhage-secondary-to-panarteritis-nodosa-at-paediatric-age-a-case-report
#2
L Salgado-Lopez, C de Quintana-Schmidt, I Catala-Antunez, J Aibar-Duran, L San Roman-Manzanera, J Molet-Teixido
INTRODUCTION: Polyarteritis nodosa is a necrotizing vasculitis that mainly affects small and medium-sized arteries in skin and internal organs. Neurological involvement is reported in around 25% of cases: ischemic stroke is relatively common, but haemorrhagic lesions are extremely rare. Subarachnoid haemorrhage in polyarteritis nodosa is an uncommon expression of this disease, mostly associated with aneurism rupture. To the best of the authors' knowledge, there is just one published case in pediatric age with polyarteritis nodosa and subarachnoid haemorrhage with no underlying aneurismal disease...
May 16, 2018: Revista de Neurologia
https://www.readbyqxmd.com/read/29725971/a-comprehensive-review-of-stem-cells-for-cartilage-regeneration-in-osteoarthritis
#3
Gauthaman Kalamegam, Adnan Memic, Emma Budd, Mohammed Abbas, Ali Mobasheri
Osteoarthritis (OA) is an age related joint disease associated with degeneration and loss of articular cartilage. Consequently, OA patients suffer from chronic joint pain and disability. Weight bearing joints and joints that undergo repetitive stress and excessive 'wear and tear' are particularly prone to developing OA. Cartilage has a poor regenerative capacity and current pharmacological agents only provide symptomatic pain relief. OA patients that respond poorly to conventional therapies are ultimately treated with surgical procedures to promote cartilage repair by implantation of artificial joint structures (arthroplasty) or total joint replacement (TJR)...
May 4, 2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29717986/aortic-dissecting-aneurysm-associated-with-systemic-arterial-hypertension-in-a-cat
#4
V Gouni, S Papageorgiou, J Debeaupuits, C Damoiseaux, J Pouchelon, V Chetboul
Aortic dissection is characterized by a tear in the aortic wall resulting in blood from the aortic lumen penetrating into the media, which causes dissection. When aortic dissection does not cause rupture, it provokes localized dilation of the aorta or aneurism, also called dissecting aortic aneurism (DAA). This case report describes a DAA in a cat associated with systemic arterial hypertension (SAHT). A 10-year-old male Domestic shorthair cat was presented for cardiac evaluation. Anamnestic clinical complaints were a syncope associated with paraparesis and weak femoral pules...
May 2018: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29701420/lumbar-cerebrospinal-fluid-drainage-in-endovascular-aortic-repair-reference-centre-experience
#5
Ana Margarida Martins, Marisa Silva, Maria de Lurdes Castro, Ana Ferro
INTRODUCTION: Spinal cord ischemia (SCI) and the resulting paraplegia are one of the most feared postoperative complications after thoraco-abdominal aortic surgery, with an incidence 4,3-8,0% after thoracic endovascular aortic repair (TEVAR), increasing patients morbi-mortality. Lumbar cerebrospinal fluid (CSF) drainage catheter is recommended as preventive measure in high risk patients. OBJECTIVE: To evaluate the efficiency and safety of CSF drainage catheter as preventive or therapeutic measure in endovascular aortic repair (EAR)...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29701408/percutaneous-treatment-pseudo-aneurism-of-the-hand-in-hemophilic-patient
#6
Vítor Ferreira, Arlindo Matos, Duarte Rego, João Gonçalves, Gabriela Teixeira, Inês Antunes, Carlos Veiga, Daniel Mendes, Joana Martins, Rui Almeida
INTRODUCTION: Pseudo aneurysms of the hand are infrequent lesions, usually associated with perforating trauma. The diagnosis is based on clinical suspicion and image confirmation of a pulsatile swelling. Various treatment modalities are currently described in the literature. METHODS: Presentation of a clinical case and discussion of the treatment strategy instituted. RESULTS: Clinical case: Man, 35 years old, with hemophilia A. History of perforating trauma of the palmar face of the right hand 3 weeks ago, having been sutured in the local hospital...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29701393/igg4-disease-and-slerosing-aortitis
#7
Bruno Fernandes, Rui Anacleto, Lina Carvalho
INTRODUCTION: IgG4-related disease (IgG4-RD) is an immune- -mediated fibro-inflammatory condition with unknown etiology that can affect various organs. Although its prevalence is still unknown, it appears to be more frequent in adult males. Cardiovascular manifestations are rare and can include idiopathic retroperitoneal periaortic fibrosis, inflammatory aortic aneurism, inflammatory periarteritis and inflammatory pericarditis. Vascular involvement is a well-recognized feature and large vessel commitment, especially the aorta, can be the only manifestation of the disease...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29676867/-image-of-the-month-left-ventricle-apical-aneurism-apical-outpouching-in-a-context-of-apical-hypertrophic-cardiomyopathy
#8
V Weerts, P J Bruyère, C Acasandrei, P Lancellotti, L Davin
No abstract text is available yet for this article.
April 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29619932/mortality-and-morbidity-in-patients-with-osteogenesis-imperfecta-in-denmark
#9
Lars Folkestad
Ostegenesis imperfecta (OI) is a hereditary disease of the connective tissue caused by mutations to, mainly, the genes that are involved in the biosynthesis of collagen type 1. Patients are grouped according to clinical severity and mode of inheritance according to Sillence's classification (originally 1979, updated 2014). According to our data, the population prevalence of OI in Denmark was 10.3 per 100,000, with 575 patients registered with an OI diagnosis in the National Patient Register and alive at the end of 2012 out of a total population of 5,602,628 persons...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29569194/hematological-and-histopathological-effects-of-silver-nanoparticles-in-rainbow-trout-oncorhynchus-mykiss-how-about-increase-of-salinity
#10
Hamid Salari Joo, Mohammad Reza Kalbassi, Seyed Ali Johari
Hematological and histopathological toxicities of silver nanoparticles (Ag-NPs) to rainbow trout were assessed in three water salinities: 0.4 ppt (low salinity), 6 ± 0.3 ppt (moderate salinity), and 12 ± 0.2 ppt (high salinity). The concentrations of Ag-NPs in the low salinity were 0.032, 0.1, 0.32, and 1 ppm, and in the moderate and high salinities were 3.2, 10, 32, and 100 ppm. The results indicated a concentration-dependently increased (thrombocyte, monocyte, and large lymphocyte) and decreased (neutrophil and small lymphocyte) white blood cell count in the Ag-NP treatments in the low salinity than the other ones in the moderate and high salinities...
March 22, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29557626/a-case-report-incomplete-kawasaki-disease-in-a-hypogammaglobulin%C3%A3-mie-child
#11
Burçin Şanlidag, Ceyhun Balkan, Nerin Bahçeciler
Kawasaki Disease (KD) is a systemic autoimmune vasculitis that affects small and medium sized vessels. Main complication of Kawasaki Disease is coronary artery aneurism, which has higher risk in case of delayed diagnosis and treatment. Although, complete and incomplete KD cases in different types of immune deficiency diseases have been presented up to date, clinical course of KD in patients with hypogammaglobulinemia (HG) has not been reported. Herein, a case diagnosed as incomplete KD in a child with transient HG of infancy has been reported...
April 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29541984/effects-of-silver-nanoparticles-on-stress-biomarkers-of-channa-striatus-immuno-protective-or-toxic
#12
Neeraj Kumar, Kishore Kumar Krishnani, Sanjay Kumar Gupta, Narendra Pratap Singh
Nanotechnology is a novel arena with promising applications in the field of medicine, industry, and agriculture including fisheries. Cross-disciplinary interactions and the application of this technology in biological systems have led to the innovation of novel nanoparticle antioxidants, which are the subject of our study. In context with above background, we designed an experiment on nano-silver to elucidate its role for mitigation of abiotic and biotic stress. Three diets were formulated viz. silver nanoparticles (Ag-NPs) incorporated at 0...
March 14, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29535518/noninvasive-visualization-of-early-osteoarthritic-cartilage-using-targeted-nanosomes-in-a-destabilization-of-the-medial-meniscus-mouse-model
#13
Hongsik Cho, Byoung Ju Kim, Sang-Hyug Park, Karen A Hasty, Byoung-Hyun Min
Background: Early stage osteoarthritis (OA) is clinically asymptomatic due to the avascular and the aneural nature of the cartilage tissue. Nevertheless, early detection of cartilage tissue is critical in order to impede the progression of OA. Hence, in order to develop effective preventive therapy for OA, diagnosis in the early stages is necessary. Methods: To achieve this goal, we have developed targeted, fluorescent nanosomes conjugated with monoclonal anti-type II collagen antibodies (MabCII) for diagnosis of early OA...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29466223/-quality-of-life-of-patients-with-the-ascending-aorta-aneurism-after-valve-sparing-surgery
#14
A M CHernyavskiy, D V Doronin, D S Khvan, S A Alsov, D A Sirota, M M Lyashchenko, V I Safina
No abstract text is available yet for this article.
September 2017: Kardiologiia
https://www.readbyqxmd.com/read/29462491/the-beta-adrenergic-agonist-salbutamol-modulates-neuromuscular-junction-formation-in-zebrafish-models-of-human-myasthenic-syndromes
#15
Grace McMacken, Dan Cox, Andreas Roos, Juliane Müller, Roger Whittaker, Hanns Lochmüller
Inherited defects of the neuromuscular junction (NMJ) comprise an increasingly diverse range of disorders, termed congenital myasthenic syndromes (CMS). Therapies acting on the sympathetic nervous system, including the selective β2 adrenergic agonist salbutamol and the α and β adrenergic agonist ephedrine, have become standard treatment for several types of CMS. However, the mechanism of the therapeutic effect of sympathomimetics in these disorders is not understood. Here, we examined the effect of salbutamol on NMJ development using zebrafish with deficiency of the key postsynaptic proteins Dok-7 and MuSK...
May 1, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29461753/-kawasaki-disease-an-update
#16
Sabrina Bressieux-Degueldre, Damien Schaffner, Michaël Hofer, Nicole Sekarski, Federica Vanoni
The cause of Kawasaki disease (KD) is still unknown, but an infectious origin and genetic susceptibility have been suggested. The American Heart Association has changed the guidelines for diagnosis and treatment of KD in 2017. One goal is to better identify patients most at risk, particularly young children with « incomplete » KD. In case of intravenous immunoglobulin resistance, alternative treatments to the traditional use of corticosteroids, such as TNF-alpha inhibitors have been proposed. For all patients with coronary aneurisms, regular assessment of myocardial perfusion is recommended, either with stress echocardiography, MRI, scintigraphy or PET-scan...
February 14, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29421424/renal-fenestration-closure-technique-in-fenestrated-endovascular-repair-for-pararenal-aortic-aneurysm
#17
Enrico Gallitto, Mauro Gargiulo, Gianluca Faggioli, Alessia Sonetto, Chiara Mascoli, Rodolfo Pini, Mohamhed Abualhin, Andrea Stella
PURPOSE: To describe an endovascular technique to close a renal artery fenestration during fenestrated endograft implant for a pararenal abdominal aortic aneurysm (p-AAA) without interfering with other visceral vessels. REPORT: A 76-year-old man with p-AAA underwent repair by a 4 fenestrations custom-made endograft. At the intraprocedural angiography, the right renal artery was occluded. To avoid a high-flow endoleak from fenestration, we performed the following technique: a 9F-steerable sheath was used to advance a 7F sheath through the fenestration into aneurism...
February 5, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29419648/vascular-dysfunction-in-exfoliation-syndrome
#18
Gábor Holló
Both exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) are associated with systemic vascular diseases and abnormalities. Though no uniform relationship between XFS/XFG and clinical systemic vascular diseases has been established across various populations, vascular dysfunction with or without clinically significant consequences has been repeatedly detected with both epidemiological and pathophysiological methods. Elevated plasma homocysteine, reduced cutaneous capillary flow reactions, damaged conduit artery dysfunction, impaired baroreflex sensitivity, parasympathetic cardiovascular neuropathy, and pathological heart rate variability indices have all been shown in XFS and XFG...
February 6, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29391165/stochastic-clonal-expansion-of-superstars-enhances-the-reserve-capacity-of-enteric-nervous-system-precursor-cells
#19
Dongcheng Zhang, James M Osborne, Kwaku Dad Abu-Bonsrah, Bevan L Cheeseman, Kerry A Landman, Boaz Jurkowicz, Donald F Newgreen
We quantified cell population increase in the quail embryo enteric nervous system (ENS) from E2.5 (about 1500 cells) to E12 (about 8 million cells). We then probed ENS proliferative capacity by grafting to the chorio-allantoic membrane large (600 cells) and small (40 cells) populations of enteric neural crest (ENC) cells with aneural gut. This demonstrated that ENC cells show an extremely high capacity to regulate their proliferation while forming the ENS. Previous mathematical models and clonal label experiments revealed that a few dominant ENS "superstar" cell clones emerge but most clones are small...
January 31, 2018: Developmental Biology
https://www.readbyqxmd.com/read/29357959/a-rare-case-of-a-patient-with-aortic-root-aneurysm-bicuspid-aortic-valve-and-scimitar-syndrome-with-anomalous-venous-return-to-the-right-superior-pulmonary-vein
#20
Kamran Ahmadov, Catherine A Beigelman, Matthias Kirsch
A rare case of Scimitar Syndrome with an abnormal drainage of the right lower pulmonary vein into the right superior pulmonary vein associated with aortic root aneurism and bicuspid aortic valve is reported.
April 2018: Cardiology in the Young
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