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https://www.readbyqxmd.com/read/29652288/absent-superior-vena-cava-in-tetralogy-of-fallot
#1
Tejas R Shah, Channabasavaraj S Hiremath, Anitha Diwakar, Krishna Manohar Soman Rema
Absent superior vena cava (SVC) is an asymptomatic congenital systemic venous anomaly which is rarely detected and compatible with normal life. Undiagnosed absent SVC may cause problems during cardiac catheterization or cardiac surgery. We present our surgical experience in a patient with tetralogy of Fallot who had undiagnosed absent SVC.
April 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29644405/abnormalities-in-left-ventricular-rotation-are-inherent-in-young-children-with-repaired-tetralogy-of-fallot-and-are-independent-of-right-ventricular-dilation
#2
Ruchika Karnik, Santosh C Uppu, Meghan Tozzi, John Doucette, Irene D Lytrivi, Miwa Geiger, Berthold Klas, Ira A Parness, Rajesh Shenoy, Hari Rajagopal, Shubhika Srivastava
Left ventricular (LV) dysfunction is a risk factor for adverse outcomes in older children and adults with repaired Tetralogy of Fallot (rToF). Pulmonary regurgitation (PR), right ventricular (RV) dilation, and dysfunction have been shown to result in abnormal LV myocardial mechanics and dysfunction. The aim of our study was to evaluate LV rotational mechanics, especially apical rotation in young children with rToF with and without RV dilation. This is a retrospective, single center study in 28 asymptomatic young children with rToF (16 with RV dilation; 12 without RV dilation); 29 age-matched normal controls...
April 11, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29627138/longitudinal-changes-in-right-ventricular-function-in-tetralogy-of-fallot-in-the-initial-years-after-surgical-repair
#3
Michael P DiLorenzo, Okan U Elci, Yan Wang, Anirban Banerjee, Tomoyuki Sato, Bonnie Ky, Elizabeth Goldmuntz, Laura Mercer-Rosa
BACKGROUND: Right ventricular (RV) dysfunction is associated with adverse long-term outcomes in patients with tetralogy of Fallot. Little is known about RV function in the first years after surgical repair. The aim of this study was to investigate perioperative changes in myocardial deformation using global longitudinal strain. METHODS: A retrospective analysis of patients with surgically repaired tetralogy of Fallot was performed. Global longitudinal peak systolic RV strain was measured on early postoperative echocardiograms, two subsequent postoperative echocardiograms through 2 years postoperatively, and preoperative echocardiograms, when available...
April 4, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29621304/trends-in-congenital-anomalies-in-europe-from-1980-to-2012
#4
Joan K Morris, Anna L Springett, Ruth Greenlees, Maria Loane, Marie-Claude Addor, Larraitz Arriola, Ingeborg Barisic, Jorieke E H Bergman, Melinda Csaky-Szunyogh, Carlos Dias, Elizabeth S Draper, Ester Garne, Miriam Gatt, Babak Khoshnood, Kari Klungsoyr, Catherine Lynch, Robert McDonnell, Vera Nelen, Amanda J Neville, Mary O'Mahony, Anna Pierini, Annette Queisser-Luft, Hanitra Randrianaivo, Judith Rankin, Anke Rissmann, Jennifer Kurinczuk, David Tucker, Christine Verellen-Dumoulin, Diana Wellesley, Helen Dolk
BACKGROUND: Surveillance of congenital anomalies is important to identify potential teratogens. METHODS: This study analysed the prevalence of 61 congenital anomaly subgroups (excluding chromosomal) in 25 population-based EUROCAT registries (1980-2012). Live births, fetal deaths and terminations of pregnancy for fetal anomaly were analysed with multilevel random-effects Poisson regression models. RESULTS: Seventeen anomaly subgroups had statistically significant trends from 2003-2012; 12 increasing and 5 decreasing...
2018: PloS One
https://www.readbyqxmd.com/read/29617968/tetralogy-of-fallot-with-aortopulmonary-window-and-interrupted-aortic-arch-multimodality-imaging-in-a-rare-association
#5
Miarisoa Ratsimandresy, Fabio Cuttone, Yves Dulac, Philippe Acar, Khaled Hadeed
No abstract text is available yet for this article.
March 30, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29617802/tetralogy-of-fallot-with-critical-biventricular-dysfunction-is-surgical-correction-achievable
#6
Grégoire Cousin, Miarisoa Ratsimandresy, Bertrand Leobon, Fabio Cuttone
We describe the case of a 32-month-old patient from a developing country with tetralogy of Fallot associated with a severe biventricular dysfunction. This association is rare but makes the surgical strategy complex and potentially contraindicated. An acute severe hypoxic episode led us to perform palliative rescue intervention involving the placement of an undersized systemic-to-pulmonary shunt. This surgery was well tolerated and allowed a fast and impressive recovery of the ventricular function, making complete repair possible...
April 2, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29614910/one-stage-repair-of-tetralogy-of-fallot-and-pseudoaneurysm-of-the-ascending-aorta-after-central-shunt
#7
Ashish Katewa, Kanwaljeet Anand, Balswaroop Sahu
Pseudoaneurysm of the ascending aorta following a central aortopulmonary shunt is a rare and potentially fatal complication. Loss of pulmonary artery continuity is another complication following an aortopulmonary shunt. We report an unusual combination of these two complications following an aortopulmonary shunt performed in a child with tetralogy of Fallot. This was managed successfully along with intracardiac repair of tetralogy of Fallot incorporating only the left pulmonary artery.
January 1, 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29614908/two-cases-of-aortic-root-replacement-after-fontan-completion
#8
Kenji Suzuki, Takahiko Sakamoto, Narutoshi Hibino, Shigeyuki Aomi, Toshiharu Shin'oka, Kenji Yamazaki
Aortic root dilatation is a well-known complication in patients with congenital aortic valve malformation, tetralogy of Fallot, or a double outlet right ventricle. We report two rare patients who underwent composite graft replacement of the aortic root with a mechanical valve, the so-called Bentall-type operation, after Fontan completion. The pathological examination on the resected aortic wall revealed mucoid degeneration in tunica media and elastic fiber fragmentation. Our report emphasizes the need for close observation of these patients over a long-term period...
January 1, 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29610128/renin-angiotensin-aldosterone-system-inhibitors-for-right-ventricular-dysfunction-in-tetralogy-of-fallot-quo-vadis
#9
EDITORIAL
Sushma Reddy, Daniel Bernstein, Jane W Newburger
No abstract text is available yet for this article.
April 3, 2018: Circulation
https://www.readbyqxmd.com/read/29605620/-incidence-and-evolution-of-congenital-heart-disease-in-spain-from-2003-until-2012
#10
Javier Pérez-Lescure Picarzo, Margarita Mosquera González, Pello Latasa Zamalloa, David Crespo Marcos
INTRODUCTION AND OBJECTIVES: Congenital heart disease (CHD) represents the most common congenital malformation. The objective of this study was to analyse the incidence of CHD in Spain, and it is the first nationwide study so far. METHODS: A retrospective observational study was performed in order to evaluate the incidence of CHD in Spain. The administrative database (minimum basic data set) from 2003 to 2012 was analysed in children less than one year old admitted to hospital with codes of CHD (International Classification of Diseases, 9th Revision, clinical modification)...
March 29, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29590404/intraoperative-customized-double-patch-device-with-twin-sutures-for-multiple-muscular-septal-defects
#11
Gananjay G Salve, Shreepal A Jain, Bharti Sharma, Manglesh S Nimbalkar, Sandip S Katkade, Jeril Kurien, Nilesh S Bhadane, Bharat V Dalvi, Raman Krishna Kumar, Krishnanaik Shivaprakash
OBJECTIVES: Closure of multiple muscular ventricular septal defects (VSDs) remains a challenge because of anatomical complexity. METHODS: We mapped all the VSDs using en face reconstruction of the right ventricular septal surface through echocardiography and then performed an 'Intraoperative Customized Double-Patch Device' technique to surgically close them in 39 patients (male:female = 25:14). The median age of the patients was 6 months (2 months-10 years), and mean weight was 5...
March 26, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29577408/the-role-of-intraoperative-epicardial-echocardiography-in-pediatric-cardiac-surgery
#12
Erkut Ozturk, Ibrahim Cansaran Tanidir, Pelin Ayyildiz, Selman Gokalp, Hasan Candas Kafali, Murat Sahin, Yakup Ergul, Sertac Haydin, Alper Guzeltas
AIM: Our aim was to evaluate the findings and the role of intraoperative epicardial echocardiography (IEE) in the management of pediatric cardiac surgery patients. METHODS: Patients evaluated with IEE between December 2015 and December 2017 were analyzed retrospectively. Demographic data, preoperative transthoracic echocardiography (TTE), and IEE reports were evaluated. RESULTS: A total of 410 patients evaluated by IEE were included in the study...
March 25, 2018: Echocardiography
https://www.readbyqxmd.com/read/29576233/cardiac-ventricular-contractile-responses-to-chronically-increased-afterload-secondary-to-right-ventricular-outflow-obstruction-in-patients-with-tetralogy-of-fallot
#13
Kenji Sugamoto, Clara Kurishima, Yoichi Iwamoto, Hirotaka Ishido, Satoshi Masutani, Hiroya Ushinohama, Koichi Sagawa, Shiro Ishikawa, Toshihide Nakano, Hideaki Kado, Hideaki Senzaki
We examined the adaptive mechanism of the pulmonary ventricle (PV) in response to increased afterload secondary to pulmonary stenosis in tetralogy of Fallot (TOF, n = 47) and congenitally corrected transposition of the great arteries (cCTGA, n = 18), where the PV is morphologically different. We also elucidated the effects of such adaptation on systemic ventricular (SV) function. PV contractility, assessed by dp/dtmax , showed significant positive correlations with PV pressure (r = 0.82, p <0...
February 6, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29572086/influence-of-contact-force-on-voltage-mapping-a-combined-magnetic-resonance-imaging-and-electroanatomic-mapping-study-in-patients-with-tetralogy-of-fallot
#14
Elvis Teijeira-Fernandez, Hubert Cochet, Felix Bourier, Masateru Takigawa, Ghassen Cheniti, Nathaniel Thompson, Antonio Frontera, Claudia Camaioni, Gregoire Massouille, Zakaria Jalal, Nicolas Derval, Xavier Iriart, Arnaud Denis, Meleze Hocini, Michel Haissaguerre, Pierre Jais, Jean-Benoit Thambo, Frederic Sacher
BACKGROUND: Voltage criteria for ventricular mapping have been obtained from small series of patients and prioritizing high specificity. OBJECTIVE: Using tetralogy of Fallot as a model of transmural right ventricular (RV) scar and MRI as reference, we aimed to study the potential influence of contact force (CF) on voltage mapping and to define voltage cutoff values for RV scar. METHODS: Fourteen patients (age 32.6±14.3, 5 female) with repaired tetralogy of Fallot underwent high resolution cardiac MRI (1...
March 20, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29568912/clinical-study-of-prenatal-ultrasonography-combined-with-t%C3%A2-box-transcription-factor-1-as-a-biomarker-for-the-diagnosis-of-congenital-heart-disease
#15
Bingcheng Guo, Jing Xiao, Long Li, Shuanglong Wang, Lijuan Wang, Shuyong Liu
Congenital heart disease (CHD) seriously threatens fetal health. Therefore, prenatal examination to detect deformity is extremely important. The present study aimed to investigate the clinical application value of prenatal ultrasonography combined with molecular biology methods in the diagnosis of fetal CHD. A total of 1,000 pregnant women who had received fetal ultrasonography to examine fetal CHD were enrolled. Ultrasounds were performed for fetal heart examination and diagnosis, mainly on fetal heart position, size, structure and function, and heart valve morphology and function...
March 14, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29568389/computational-modeling-suggests-impaired-interactions-between-nkx2-5-and-gata4-in-individuals-carrying-a-novel-pathogenic-d16n-nkx2-5-mutation
#16
Saidulu Mattapally, Mrityunjay Singh, Kona Samba Murthy, Shailendra Asthana, Sanjay K Banerjee
NKX2.5 , a homeobox containing gene, plays an important role in embryonic heart development and associated mutations are linked with various cardiac abnormalities. We sequenced the NKX2.5 gene in 100 congenital heart disease (CHD) patients and 200 controls. Our analysis revealed a total of 7 mutations, 3 in intronic region, 3 in coding region and 1 in 3' UTR. Of the above mutations, one mutation was found to be associated with tetralogy of fallot (TOF) and two (rs2277923 and a novel mutation, D16N) were strongly associated with VSD...
March 2, 2018: Oncotarget
https://www.readbyqxmd.com/read/29546472/transcatheter-pulmonary-valve-replacement-current-state-of-art
#17
REVIEW
Wail Alkashkari, Amani Alsubei, Ziyad M Hijazi
PURPOSE OF REVIEW: The past couple of decades have brought tremendous advances to the field of pediatric and adult congenital heart disease (CHD). Percutaneous valve interventions are now a cornerstone of not just the congenital cardiologist treating patients with congenital heart disease, but also-and numerically more importantly-for adult interventional cardiologists treating patients with acquired heart valve disease. Transcatheter pulmonary valve replacement (tPVR) is one of the most exciting recent developments in the treatment of CHD and has evolved to become an attractive alternative to surgery in patients with right ventricular outflow tract (RVOT) dysfunction...
March 15, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29544482/investigation-of-associated-factors-with-post-operative-outcomes-in-patients-undergoing-tetralogy-of-fallot-correction
#18
Ahmad Ali Amirghofran, Jamshid Badr, Mansour Jannati
BACKGROUND: Tetralogy of Fallot (TOF) is one of the congenital cardiac abnormality which occurs during embryonic time. Although surgical correction, especially early operation, is the best way to treat patients, still contributing factors in morbidity and mortality is controversial. The objective of this study is to investigate potential factors which might be correlated with post-operative outcomes of TOF. METHODS: In this retrospective study, 349 monitored patients with TOF correction were selected...
March 15, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29544424/association-of-habitual-activity-and-body-mass-index-in-survivors-of-congenital-heart-surgery-a-study-of-children-and-adolescents-with-tetralogy-of-fallot-transposition-of-the-great-arteries-and-fontan-palliation
#19
Michael L O'Byrne, Michael G McBride, Stephen Paridon, Elizabeth Goldmuntz
BACKGROUND: Obesity is associated with increased lifelong morbidity and reduced life span and is increasingly prevalent in the congenital heart disease population. Habitual exercise is an important aspect of a healthy lifestyle and primary prevention of obesity in the general population. The association between habitual activity and body mass index (BMI) has not been studied in children with congenital heart disease. METHODS: A cross-sectional analysis of two previously collected cohorts was performed, including participants 8 to 18 years old with tetralogy of Fallot, transposition of the great arteries, and single ventricle heart disease after a Fontan operation...
March 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29544416/anesthetic-management-during-surgery-for-tetralogy-of-fallot-with-pulmonary-atresia-and-major-aortopulmonary-collateral-arteries
#20
Zoel A Quinonez, Laura Downey, Rania K Abbasi, Calvin Kuan, Ritu Asija, Doff B McElhinney, Frank L Hanley, Richard D Mainwaring, Lisa Wise-Faberowski
Tetralogy of Fallot with pulmonary atresia and major aortopulmonary collaterals (TOF/PA/MAPCAs) is a heterogeneous disease with varying degrees of severity, requiring complex anesthetic management. Our institution has adopted the approach of early complete repair with incorporation of all lung segments, extensive lobar and branch segmental pulmonary artery reconstruction, and ventricular septal defect closure. While the surgical management of TOF/PA/MAPCAs has been extensively described and varies depending on the institution, there is a paucity of literature on the anesthetic management for such procedures...
March 2018: World Journal for Pediatric & Congenital Heart Surgery
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