keyword
https://read.qxmd.com/read/38492923/hepatitis-c-elimination-in-rwanda-progress-feasibility-and-economic-evaluation
#21
JOURNAL ARTICLE
Huaiyang Zhong, Alec Aaron, Lindsey Hiebert, Janvier Serumondo, Yueran Zhuo, Madeline Adee, Gallican N Rwibasira, John W Ward, Jagpreet Chhatwal
OBJECTIVE: In 2018, Rwanda launched a national program to eliminate the hepatitis C virus (HCV). We aim to assess the impact of the program to date and identify strategies to achieve the World Health Organization's HCV elimination goals by 2030. METHODS: We developed a microsimulation model to simulate Rwanda's HCV epidemic from 2015 through 2050 and evaluated temporal trends in HCV infection, prevalence, mortality, and the total cost of care for scenarios that could achieve HCV elimination by 2030...
March 14, 2024: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://read.qxmd.com/read/38492740/self-identified-prescriber-tendencies-in-sodium-glucose-cotransporter-2-inhibitor-outpatient-prescribing
#22
JOURNAL ARTICLE
Kristen Thompson, Brandi L Bowers, Ashley M Evans
BACKGROUND: Despite expanded indications and demonstrated cardiovascular and renal benefits, prescribing rates of SGLT-2 inhibitors are low. OBJECTIVES: The study aimed to identify factors impacting prescriber decision-making when prescribing SGLT-2 inhibitors in the outpatient setting and identify differences across specialties in self-identified prescribing patterns. METHODS: An anonymous survey was administered electronically to prescribers in relevant specialties at a large community health system...
March 14, 2024: Journal of the American Pharmacists Association: JAPhA
https://read.qxmd.com/read/38492179/budget-impact-analyses-for-treatment-of-heart-failure-a-systematic-review
#23
REVIEW
Abedin Teimourizad, Abdosaleh Jafari, Firooz Esmaeilzadeh
Heart failure (HF) is increasing globally and turning out to be a serious worldwide public health problem with significant morbidity and mortality. This study aims to systemically review the budget impact analysis of heart failure treatments on health care expenditure worldwide. Scientific databases such as PubMed, Web of Science, Scopus, and Google Scholar were searched for budget impact analysis and heart failure treatments, over January 2001 to August 2023. The quality assessment of the selected studies was evaluated through ISPOR practice guideline...
March 16, 2024: Heart Failure Reviews
https://read.qxmd.com/read/38492119/outcomes-and-costs-with-the-introduction-of-robotic-assisted-thoracic-surgery-in-public-hospitals
#24
JOURNAL ARTICLE
Léa Betser, Alicia Le Bras, Harry Etienne, Arnaud Roussel, Antonio Bobbio, Charles Al-Zreibi, Emmanuel Martinod, Marco Alifano, Yves Castier, Jalal Assouad, Isabelle Durand-Zaleski, Pierre Mordant
Robotic-assisted thoracic surgery (RATS) is an effective treatment of non-small cell lung cancer (NSCLC) but the effects of its implementation in university hospital networks has not been described. We analyzed the early clinical outcomes, estimated costs, and revenues associated with three robotic systems implemented in the Paris Public Hospital network. A retrospective study included patients who underwent RATS for NSCLC in 2019 and 2020. Ninety-day morbidity, mortality, hospital costs, and hospital revenues were described...
March 16, 2024: Journal of Robotic Surgery
https://read.qxmd.com/read/38492098/impact-of-reimbursement-systems-on-patient-care-a-systematic-review-of-systematic-reviews
#25
REVIEW
Eva Wagenschieber, Dominik Blunck
BACKGROUND: There is not yet sufficient scientific evidence to answer the question of the extent to which different reimbursement systems influence patient care and treatment quality. Due to the asymmetry of information between physicians, health insurers and patients, market-based mechanisms are necessary to ensure the best possible patient care. The aim of this study is to investigate how reimbursement systems influence multiple areas of patient care in form of structure, process and outcome indicators...
March 16, 2024: Health Economics Review
https://read.qxmd.com/read/38491995/public-versus-private-care-in-the-military-health-system-evidence-from-low-back-pain-patients
#26
JOURNAL ARTICLE
Christopher G Leggett, Rachel O Schmidt, Jonathan Skinner, Jon D Lurie, William Patrick Luan
INTRODUCTION: There is a longstanding debate about whether health care is more efficiently provided by the public or private sector. The debate is particularly relevant to the Military Health System (MHS), which delivers care through a combination of publicly funded federal facilities and privately contracted providers. This study compares outcomes, treatments, and costs for MHS patients obtaining care for low back pain (LBP) from public versus private providers. MATERIALS AND METHODS: A retrospective cohort study was completed using TRICARE Prime claims data from April 2015 to December 2018...
March 16, 2024: Military Medicine
https://read.qxmd.com/read/38491962/quantifying-preferences-for-urea-cycle-disorder-treatments-using-a-discrete-choice-experiment
#27
JOURNAL ARTICLE
Josiah Edelblut, Jeffrey R Skaar, John Hilton, Matthew Seibt, Kyle Martin, Nandini Hadker, Adrian Quartel, Robert D Steiner
Aims : Urea cycle disorders (UCDs) can cause ammonia accumulation and central nervous system toxicity. Nitrogen-binding medications can be efficacious but certain attributes may negatively impact adherence. This study sought to quantify the administration-related attributes influencing overall prescription selection and patient adherence. Methods: A web-based, quantitative survey including discrete choice experiment (DCE) methodology captured responses from health care providers for patients with UCDs. A series of hypothetical treatment profile sets with attributes such as route of administration, taste/odor, preparation instructions, packaging, dose measurement, and weight use restrictions were presented...
March 16, 2024: Journal of Medical Economics
https://read.qxmd.com/read/38491816/advancing-access-to-care-an-assessment-of-the-prehospital-system-in-senegal
#28
JOURNAL ARTICLE
Kamil Michalski, Moustapha Diedhiou, Matin Kerachian, Jeremy Grushka, Jacques Noel Tendeng, Mohamed Lamine Diao, Mamadou D Beye, Johana Montero Ortiz, Tarek Razek, Dan L Deckelbaum, Ibrahim Konate
BACKGROUND: Most low- and middle-income countries do not have a mature prehospital system limiting access to definitive care. This study sought to describe the current state of the prehospital system in Senegal and offer recommendations aimed at improving system capacity and population access to definitive care. METHODS: Structured interviews were conducted with key informants in various regions throughout the country using qualitative and quantitative techniques...
March 16, 2024: World Journal of Surgery
https://read.qxmd.com/read/38491799/cost-effectiveness-analysis-of-different-treatment-modalities-in-bcg-unresponsive-nmibc
#29
JOURNAL ARTICLE
Constantin Rieger, Jörg Schlüchtermann, Enno Storz, Lucas Kastner, David Pfister, Axel Heidenreich
OBJECTIVE: Radical cystectomy (RC) is the standard of care (SOC) in BCG-unresponsive NMIBC and is associated with a significant health-related quality-of-life burden. Recently, promising results have been published on Gemcitabine/Docetaxel, Pembrolizumab, and Hyperthermic Intravesical Chemotherapy (HIVEC) as salvage therapy options trying to increase the rate of bladder preservation. Here, we performed a Cost-Effectiveness-Analysis of those treatment modalities. PATIENTS AND METHODS: We developed a Markov model from a payer's perspective drawing on clinical data of single-arm trials testing intravesical gemcitabine/docetaxel and pembrolizumab in BCG-unresponsive NMIBC, as well as clinical data from patients receiving hyperthermic intravesical chemotherapy HIVEC (n = 29) as intravesical salvage chemotherapy at our uro-oncological centre in Cologne...
March 16, 2024: BJU International
https://read.qxmd.com/read/38491778/optimal-self-protection-and-health-risk-perceptions-exploring-connections-between-risk-theory-and-the-health-belief-model
#30
JOURNAL ARTICLE
Emmanuelle Augeraud-Véron, Marc Leandri
In this contribution to the longstanding risk theory debate on optimal self-protection, we aim to enrich the microeconomic modeling of self-protection, in the wake of Ehrlich and Becker (1972), by exploring the representation of risk perception at the core of the Health Belief Model (HBM), a conceptual framework extremely influential in Public Health studies (Janz and Becker, 1984). In our two-period model, we highlight the crucial role of risk perception in the individual decision to adopt a preventive behavior toward a generic health risk...
March 15, 2024: Health Economics
https://read.qxmd.com/read/38491770/harmonizing-regulatory-market-approval-of-products-with-high-safety-requirements-evidence-from-the-european-pharmaceutical-market
#31
JOURNAL ARTICLE
Fabian Grünwald, Tom Stargardt
We causally analyzed whether being a member of the European Union (EU) and having access to a centralized marketing authorization procedure (centralized procedure [CP]) affects availability and time to launch of new pharmaceuticals. We employed multiple difference-in-differences models, exploiting the eastern enlargement of the EU as well as changes in the indications that fall within the compulsory or voluntary scope of the CP. Results showed that countries experienced a mean decrease in launch delay of 10...
March 15, 2024: Health Economics
https://read.qxmd.com/read/38491755/the-impact-of-hiv-aids-on-marriage-in-the-early-years-of-the-epidemic
#32
JOURNAL ARTICLE
Hasan Shahid
The advent of the HIV/AIDS crisis transformed the desirability of committed heterosexual relationships. This paper employs a difference-in-differences approach to investigate the impact of the HIV/AIDS crisis on marriage rates. By using HIV/AIDS death rates as a proxy for HIV incidence, the study exploits county-level variations in HIV/AIDS mortality and finds that counties with higher HIV/AIDS death rates experienced larger gains in marriage rates in the early years of the epidemic. Estimates suggest that the virus increased marriage rates by approximately 0...
March 15, 2024: Health Economics
https://read.qxmd.com/read/38491738/engaging-patients-in-designing-a-transmural-allied-health-pathway-a-qualitative-exploration-of-hospital-to-home-transitions
#33
JOURNAL ARTICLE
Juul W M van Grootel, Romain J Collet, Mel E Major, Suzanne Wiertsema, Hanneke van Dongen, Marike van der Leeden, Edwin Geleijn, Raymond Ostelo, Marike van der Schaaf
INTRODUCTION: The transition from hospital to home is often suboptimal, resulting in patients not receiving the necessary allied healthcare after discharge. This may, in turn, lead to delayed recovery, a higher number of readmissions, more emergency department visits and an increase in mortality and healthcare costs. This study aimed to gain insight into patients' experiences, perceptions, and needs regarding hospital-to-home transition, focusing on allied healthcare as a first step towards the development of a transitional integrated allied healthcare pathway for patients with complex care needs after hospital discharge...
April 2024: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://read.qxmd.com/read/38491541/towards-leaving-no-one-behind-in-north-macedonia-a-mixed-methods-assessment-of-barriers-to-effective-coverage-with-health-services
#34
JOURNAL ARTICLE
Theadora Swift Koller, Jelena Kjetkovikj Janeva, Elena Ognenovska, Ana Vasilevska, Simona Atanasova, Chris Brown, Antoni Dedeu, Anne Johansen
BACKGROUND: The Government of North Macedonia's Primary Health Care reform is committed to leaving no one behind on the path to Universal health Coverage (UHC). During mid-2022 to March 2023, the World Health Organization (WHO) collaborated with the Government and other national stakeholders for an assessment of barriers to effective coverage with health services experienced by adult citizens, with a specific focus on rural areas and subpopulations in situations of vulnerability. METHODS: This study constituted the piloting of a draft forthcoming WHO handbook on assessing barriers for health services, grounded in the Tanahashi framework for effective coverage with health services...
March 15, 2024: International Journal for Equity in Health
https://read.qxmd.com/read/38491442/cost-and-economic-evidence-for-asset-based-approaches-to-health-improvement-and-their-evaluation-methods-a-systematic-review
#35
JOURNAL ARTICLE
Alice Wreford, Linda Birt, Jennifer A Whitty, Sarah Hanson, Susan Conquer, Adam P Wagner
BACKGROUND: Asset-based approaches (ABAs) tackle health inequalities by empowering people in more disadvantaged communities, or targeted populations, to better utilise pre-existing local community-based resources. Using existing resources supports individuals to better manage their own health and its determinants, potentially at low cost. Targeting individuals disengaged with traditional service delivery methods offers further potential for meaningful cost-savings, since these people often require costly care...
March 15, 2024: BMC Public Health
https://read.qxmd.com/read/38491372/tetrahedral-framework-nucleic-acids-for-improving-wound-healing
#36
REVIEW
Wanqing Zou, Jing Lu, Luyong Zhang, Duanping Sun
Wounds are one of the most common health issues, and the cost of wound care and healing has continued to increase over the past decade. In recent years, there has been growing interest in developing innovative strategies to enhance the efficacy of wound healing. Tetrahedral framework nucleic acids (tFNAs) have emerged as a promising tool for wound healing applications due to their unique structural and functional properties. Therefore, it is of great significance to summarize the applications of tFNAs for wound healing...
March 16, 2024: Journal of Nanobiotechnology
https://read.qxmd.com/read/38491318/cost-implications-of-competition-among-federally-qualified-health-centers
#37
JOURNAL ARTICLE
Seongwon Choi, Ganisher Davlyatov, William Opoku-Agyeman
Federally Qualified Health Centers (FQHCs) are pivotal in delivering healthcare services to underserved populations in the United States. While the number of FQHCs and FQHC look-alikes has been increasing, intensifying competition, limited research has examined the cost implications associated with this growing competition among FQHCs. This study aims to fill the research gap by analyzing the relationship between the level of competition among FQHCs and the cost of care per patient. Understanding this relationship is crucial for managers and policymakers in deriving informed decisions related to the expansion of FQHCs...
March 16, 2024: Journal of Community Health
https://read.qxmd.com/read/38491307/the-economic-effect-of-financial-compensation-in-china-s-healthcare-system-comprehensive-insights-regarding-supply-and-demand-factors
#38
JOURNAL ARTICLE
Yi Guo, Xuezhi Hong, Dongmei Li, Qiannan An, Wenwen Fan, Minghe Yang, Luyang Xiao
OBJECTIVES: We aim to analyse the effects of government subsidies on residents' health and healthcare expenditure from the perspectives of supply and demand. DATA AND METHODS: According to the regional division adopted in the data query system of the National Bureau of Statistics, this study divides 31 provinces and cities into three regions: eastern, central, and western. The data used are from public databases, such as the "China Statistical Yearbook," "China Health Statistical Yearbook," and "Government Final Account Report"...
March 16, 2024: Health Economics Review
https://read.qxmd.com/read/38491303/the-effect-of-breathing-exercises-and-mindset-with-or-without-cold-exposure-on-mental-and-physical-health-in-persons-with-a-spinal-cord-injury-a-protocol-for-a-three-arm-randomised-controlled-trial
#39
JOURNAL ARTICLE
Sven Hoekstra, Frank Ettema, Max van der Bijll, Vera van der Sterren, Ellen van Binsbergen, Ludwine van Orsouw, Wendy Achterberg, Hein Daanen, Thomas Janssen, Sonja de Groot
STUDY DESIGN: A three-arm randomized controlled trial. OBJECTIVES: To investigate the effects of the Wim Hof Method (WHM), with (WHM-C) and without cold exposure (WHM-NC), on mental and physical health in persons with chronic spinal cord injury (SCI). SETTING: Rehabilitation centre (assessments and once-weekly intervention sessions) and home-based (daily intervention sessions). METHODS: Sixty adults with chronic SCI will be randomised (1:1:1) to one of three groups: participants in the intervention groups (i...
March 15, 2024: Spinal Cord
https://read.qxmd.com/read/38490995/a-review-of-real-world-evidence-on-preemptive-pharmacogenomic-testing-for-preventing-adverse-drug-reactions-a-reality-for-future-health-care
#40
REVIEW
Santenna Chenchula, Shubham Atal, Chakradhara Rao S Uppugunduri
Adverse drug reactions (ADRs) are a significant public health concern and a leading cause of hospitalization; they are estimated to be the fourth leading cause of death and increasing healthcare costs worldwide. Carrying a genetic variant could alter the efficacy and increase the risk of ADRs associated with a drug in a target population for commonly prescribed drugs. The use of pre-emptive pharmacogenetic/omic (PGx) testing can improve drug therapeutic efficacy, safety, and compliance by guiding the selection of drugs and/or dosages...
March 15, 2024: Pharmacogenomics Journal
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