keyword
https://read.qxmd.com/read/38635839/comorbidities-affecting-re-admission-and-survival-in-covid-19-application-of-joint-frailty-model
#1
JOURNAL ARTICLE
Akram Yazdani, Seyyed Ali Mozaffarpur, Pouyan Ebrahimi, Hoda Shirafkan, Hamed Mehdinejad
BACKGROUND: One of the common concerns of healthcare systems is the potential for re-admission of COVID-19 patients. In addition to adding costs to the healthcare system, re-admissions also endanger patient safety. Recognizing the factors that influence re-admission, can help provide appropriate and optimal health care. The aim of this study was to assess comorbidities that affect re-admission and survival in COVID-19 patients using a joint frailty model. METHODS: This historical cohort study was done using data of patients with COVID-19 who were re-hospitalized more than twice in a referral hospital in North of Iran...
2024: PloS One
https://read.qxmd.com/read/38635662/knowledge-of-telemedicine-and-its-associated-factors-among-health-professional-in-ethiopia-a-systematic-review-and-meta-analysis
#2
JOURNAL ARTICLE
Adamu Ambachew Shibabaw, Alex Ayenew Chereka, Agmasie Damtew Walle, Addisalem Workie Demsash, Geleta Nenko Dube, Abiy Tasew Dubale, Sisay Yitayh Kassie, Gemeda Wakgari Kitil, Mesafint Zewold Jember, Chernet Desalegn Gebeyehu, Aster Temesgen Ariger, Eshetie Andargie Dires
INTRODUCTION: Telemedicine is a useful tool for decreasing hospital stress, patient suffering, ambulance needs, hospital anxiety, and costs while improving the standard of care. Nonetheless, the lack of awareness regarding telemedicine poses a barrier to its application, presenting several difficulties in underdeveloped nations like Ethiopia. This review evaluates Ethiopian-specific telemedicine knowledge and associated factors. METHODS: This systematic review was conducted using a search of several online databases in addition to the main databases, like Medline, PubMed, Scopus, and Science Direct...
2024: PloS One
https://read.qxmd.com/read/38635451/cost-related-non-adherence-to-prescribed-medicines-what-are-physicians-moral-duties
#3
JOURNAL ARTICLE
Narcyz Ghinea, Katrina Hutchison, Mianna Lotz, Wendy A Rogers
As the price of pharmaceuticals and biologicals rises so does the number of patients who cannot afford them. In this article, we argue that physicians have a moral duty to help patients access affordable medicines. We offer three grounds to support our argument: (i) the aim of prescribing is to improve health and well-being which can only be realized with secure access to treatment; (ii) there is no morally significant difference between medicines being unavailable and medicines being unaffordable, so the steps physicians are willing to take in the first case should extend to the second; and (iii) as the primary stakeholder with a duty to put the individual patient's interests first, the medical professional has a duty to address cost-barriers to patient care...
April 18, 2024: American Journal of Bioethics: AJOB
https://read.qxmd.com/read/38635308/effectiveness-and-cost-effectiveness-of-survivorship-care-for-survivors-of-hodgkin-lymphoma-insight-study-protocol-for-a-multicenter-retrospective-cohort-study-with-a-quasi-experimental-design
#4
JOURNAL ARTICLE
Eline M J Lammers, Josée M Zijlstra, Valesca P Retèl, Berthe M P Aleman, Flora E van Leeuwen, Annelies Nijdam
BACKGROUND: Hodgkin lymphoma (HL) occurs at young ages, with the highest incidence between 20 and 40 years. While cure rates have improved to 80%-90% over the past decades, survivors of HL are at substantial risk of late treatment-related complications, such as cardiovascular diseases, breast cancer, severe infections, and hypothyroidism. To reduce morbidity and mortality from late treatment effects, the Dutch Better care after lymphoma, Evaluation of long-term Treatment Effects and screening Recommendations (BETER) consortium developed a survivorship care program for 5-year survivors of HL that includes risk-based screening for and treatment of (risk factors for) late adverse events...
April 18, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38635293/untangling-the-perception-of-value-in-value-based-healthcare-an-interview-study
#5
JOURNAL ARTICLE
Axel Wolf, Annette Erichsen Andersson, Ewa Wikström, Fredrik Bååthe
PURPOSE: Value-based health care (VBHC) argues that health-care needs to re-focus to maximise value creation, defining value as the quota when dividing the outcomes important for the patient, by the cost for health care to deliver such outcomes. This study aims to explore the perception of value among different stakeholders involved in the process of implementing VBHC at a Swedish hospital to support leaders to be more efficient and effective when developing health care. DESIGN/METHODOLOGY/APPROACH: Participants comprised 19 clinicians and non-clinicians involved in the implementation of VBHC...
April 16, 2024: Leadership in Health Services
https://read.qxmd.com/read/38634917/pharmacogenetic-guided-versus-standard-warfarin-dosing-for-routine-clinical-care-with-its-pharmacoeconomic-impact-a-randomized-controlled-clinical-trial
#6
JOURNAL ARTICLE
Aishwarya Anand, Naveen C Hegde, Pulkit Chhabra, Jai Purohit, Rupesh Kumar, Ankur Gupta, Deepesh P Lad, Ritin Mohindra, Saurabh Mehrotra, Rajesh Vijayvergiya, Basant Kumar, Vishal Sharma, Pankaj Malhotra, Jasmina Ahluwalia, Reena Das, Amol N Patil, Nusrat Shafiq, Samir Malhotra
BACKGROUND: Empirical use of pharmacogenetic test(PGT) is advocated for many drugs, and resource-rich setting hospitals are using the same commonly. The clinical translation of pharmacogenetic tests in terms of cost and clinical utility is yet to be examined in hospitals of low middle income countries (LMICs). AIM: The present study assessed the clinical utility of PGT by comparing the pharmacogenetically(PGT) guided- versus standard of care(SOC)- warfarin therapy, including the health economics of the two warfarin therapies...
April 18, 2024: Annals of Hematology
https://read.qxmd.com/read/38634761/handle-with-care-transformative-learning-as-pedagogy-in-an-under-resourced-health-care-context
#7
JOURNAL ARTICLE
Jana Müller, Rhoda Meyer, Jason Bantjes, Elize Archer, Ian Couper
Issue:  A significant component of health professions education is focussed on students' exposure to the social determinants of health and the challenges that patients within the health care system face. An appropriate way to provide such exposure is through distributed clinical training. This usually entails students training in smaller groups along the continuum of care, away from tertiary academic hospitals. This also means students are away from their existing academic and social support systems. It is evident that knowledge and clinical skills alone are not sufficient to prepare students, they also need to be taught to critically reflect on how their own values and attitudes traverse their knowledge and skills to influence their practice as healthcare professionals...
April 18, 2024: Teaching and Learning in Medicine
https://read.qxmd.com/read/38634591/-clinical-and-economic-justification-of-icg-cholangiography-in-%C3%A2-difficult%C3%A2-laparoscopic-cholecystectomy
#8
JOURNAL ARTICLE
P N Romashchenko, A K Aliev, A S Pryadko, Sh Yu Abasov, N A Maistrenko
OBJECTIVE: To prove from a clinical and economic point of view the expediency of using ICG cholangiography in patients with «difficult» laparoscopic cholecystectomy for the prevention of damage to the bile ducts. MATERIAL AND METHODS: The results of treatment of 173 patients with cholelithiasis at various levels of health care providing were analyzed with regard to assessment of indicators of surgery complexity, developed complications and economic costs...
2024: Khirurgiia
https://read.qxmd.com/read/38634535/relationship-between-staff-and-quality-of-care-in-care-homes-starq-mixed-methods-study
#9
Karen Spilsbury, Andy Charlwood, Carl Thompson, Kirsty Haunch, Danat Valizade, Reena Devi, Cornell Jackson, David Phillip Alldred, Antony Arthur, Lucy Brown, Paul Edwards, Will Fenton, Heather Gage, Matthew Glover, Barbara Hanratty, Julienne Meyer, Aileen Waton
BACKGROUND: Quality of life and care varies between and within the care homes in which almost half a million older people live and over half a million direct care staff (registered nurses and care assistants) work. The reasons are complex, understudied and sometimes oversimplified, but staff and their work are a significant influence. OBJECTIVE(S): To explore variations in the care home nursing and support workforce; how resident and relatives' needs in care homes are linked to care home staffing; how different staffing models impact on care quality, outcomes and costs; how workforce numbers, skill mix and stability meet residents' needs; the contributions of the care home workforce to enhancing quality of care; staff relationships as a platform for implementation by providers...
April 2024: Health Soc Care Deliv Res
https://read.qxmd.com/read/38634483/bisphosphonate-alternative-regimens-for-the-prevention-of-osteoporotic-fragility-fractures-blast-off-a-mixed-methods-study
#10
JOURNAL ARTICLE
Opinder Sahota, Melanie Narayanasamy, Anastasios Bastounis, Zoe Paskins, Simon Bishop, Tessa Langley, Neil Gittoes, Sarah Davis, Ann Baily, Moira Holmes, Jo Leonardi-Bee
BACKGROUND: Bisphosphonates are a class of medication commonly used to treat osteoporosis. Alendronate is recommended as the first-line treatment; however, long-term adherence (both treatment compliance and persistence) is poor. Alternative bisphosphonates are available, which can be given intravenously and have been shown to improve long-term adherence. However, the most clinically effective and cost-effective alternative bisphosphonate regimen remains unclear. What is the most cost-effective bisphosphonate in clinical trials may not be the most cost-effective or acceptable to patients in everyday clinical practice...
April 2024: Health Technology Assessment: HTA
https://read.qxmd.com/read/38634428/they-do-their-utmost-promise-and-limits-of-palliative-care-in-two-refugee-camps-in-rwanda-a-qualitative-study
#11
JOURNAL ARTICLE
Sonya de Laat, Emmanuel R Musoni, Kevin Bezanson, Rachel Yantzi, Olive Wahoush, Elysée Nouvet, Matthew Hunt, Takhliq Amir, Carrie Bernard, Christian Ntizimira, Lisa Schwartz
After often gruelling journeys, some refugees arrive at secure locations with severe injury or illness. Others find themselves shortly thereafter facing a life-limiting health condition. Palliative care has been the focus of recent research, and of academic and aid sector dialogue. In this study, we ask: What are experiences and needs of patients and care providers? What opportunities and obstacles exist to enhance or introduce means of reducing suffering for patients facing serious illness and injury in crisis settings? We present findings of a qualitative sub-study within a larger programme of research exploring moral and practical dimensions of palliative care in humanitarian crisis contexts...
April 18, 2024: Medicine, Conflict, and Survival
https://read.qxmd.com/read/38634415/evaluation-of-venous-thromboembolism-risk-assessment-models-for-hospital-inpatients-the-vteam-evidence-synthesis
#12
Daniel Edward Horner, Sarah Davis, Abdullah Pandor, Helen Shulver, Steve Goodacre, Daniel Hind, Saleema Rex, Michael Gillett, Matthew Bursnall, Xavier Griffin, Mark Holland, Beverley Jane Hunt, Kerstin de Wit, Shan Bennett, Robin Pierce-Williams
BACKGROUND: Pharmacological prophylaxis during hospital admission can reduce the risk of acquired blood clots (venous thromboembolism) but may cause complications, such as bleeding. Using a risk assessment model to predict the risk of blood clots could facilitate selection of patients for prophylaxis and optimise the balance of benefits, risks and costs. OBJECTIVES: We aimed to identify validated risk assessment models and estimate their prognostic accuracy, evaluate the cost-effectiveness of different strategies for selecting hospitalised patients for prophylaxis, assess the feasibility of using efficient research methods and estimate key parameters for future research...
April 2024: Health Technology Assessment: HTA
https://read.qxmd.com/read/38634413/a-novel-tgf%C3%AE-r2-splice-variant-in-patient-with-aortic-aneurysm-and-family-history-for-aortic-dissection-a-case-report
#13
JOURNAL ARTICLE
Cecilia Vecoli, Ilenia Foffa, Simona Vittorini, Nicoletta Botto, Augusto Esposito, Sabrina Costa, Valeria Piagneri, Pierluigi Festa, Lamia Ait-Ali
We report the clinical presentation and genetic screening of a 31-year-old man with dilatation of the aortic root and ascending aorta and a positive family history for aortic dissection and sudden death. A novel heterozygous variant in a splice acceptor site (c.1600-1G>T) of TGFβR2 gene was identified by using a targeted multi-gene panel analysis. Bioinformatics tools predicted that the c.1600-1G>T variant is pathogenic by altering acceptor splice site at - 1 position affecting pre-mRNA splicing...
April 18, 2024: Personalized Medicine
https://read.qxmd.com/read/38634396/perspective-health-economic-interests-at-nimh-and-nida-to-improve-delivery-of-behavioral-health-services
#14
JOURNAL ARTICLE
Jennifer L Humensky, Sarah Q Duffy, Leonardo Cubillos, Michael C Freed, Agnes Rupp
BACKGROUND: Effective financing mechanisms are essential to ensuring that people can access and utilize effective treatments and services. Financing mechanisms are needed not only to pay for the delivery of those treatments and services, but also ancillary costs, while also keeping care affordable. AIMS: This article highlights key areas of the interest of the National Institute of Mental Health (NIMH) and the National Institute on Drug Abuse (NIDA) in supporting applied health economics and health care financing research...
March 1, 2024: Journal of Mental Health Policy and Economics
https://read.qxmd.com/read/38634395/perspective-a-path-to-value-based-insurance-design-for-mental-health-services
#15
JOURNAL ARTICLE
Michael C Freed, Jennifer L Humensky, Patricia A Arean
BACKGROUND: Aligning cost of mental health care with expected clinical and functional benefits of that care would incentivize the delivery of high value treatments and services. In turn, ineffective or untested care could still be offered but at costs high enough to offset the delivery of high value care. AIMS: The authors comment on Benson and Fendrick's paper on Value-Based Insurance Design (VBID) for mental health in the September 2023 special issue of this journal...
March 1, 2024: Journal of Mental Health Policy and Economics
https://read.qxmd.com/read/38634394/the-economic-burden-of-chronic-psychotic-disorders-an-incidence-based-cost-of-illness-approach
#16
JOURNAL ARTICLE
Claire de Oliveira, Bryan Tanner
BACKGROUND: The economic burden of chronic psychotic disorders is substantial. However, few studies have employed an incidence based approach to estimate the economic burden of chronic psychotic disorders. Furthermore, the existing work has mainly used models populated with data obtained from published literature, making several assumptions to estimate incidence-based costs. AIMS OF THE STUDY: The objective of this study was to estimate the direct cumulative mean health care costs of chronic psychotic disorders, using an incidence-based, cost-of-illness approach and real-world data from a single-payer health care system...
March 1, 2024: Journal of Mental Health Policy and Economics
https://read.qxmd.com/read/38634393/effectiveness-of-antidepressants-in-combination-with-psychotherapy
#17
JOURNAL ARTICLE
Farrokh Alemi, Tulay G Soylu, Mary Cannon, Conor McCandless
BACKGROUND: Consensus-guidelines for prescribing antidepressants recommend that clinicians should be vigilant to match antidepressants to patient's medical history but provide no specific advice on which antidepressant is best for a given medical history. AIMS OF THE STUDY: For patients with major depression who are in psychotherapy, this study provides an empirically derived guideline for prescribing antidepressant medications that fit patients' medical history...
March 1, 2024: Journal of Mental Health Policy and Economics
https://read.qxmd.com/read/38634070/risk-factors-for-colonization-with-extended-spectrum-cephalosporin-resistant-and-carbapenem-resistant-enterobacterales-among-hospitalized-patients-in-guatemala-an-antibiotic-resistance-in-communities-and-hospitals-arch-study
#18
JOURNAL ARTICLE
Mark A Caudell, Carmen Castillo, Lucas F Santos, Laura Grajeda, Juan Carlos Romero, Maria Renee Lopez, Sylvia Omulo, Mariangeli Freitas Ning, Guy H Palmer, Douglas R Call, Celia Cordon-Rosales, Rachel M Smith, Carolyn T A Herzig, Ashley Styczynski, Brooke M Ramay
OBJECTIVES: The spread of extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) and carbapenem-resistant Enterobacterales (CRE) has resulted in increased morbidity, mortality, and health care costs worldwide. To identify the factors associated with ESCrE and CRE colonization within hospitals, we enrolled hospitalized patients at a regional hospital located in Guatemala. METHODS: Stool samples were collected from randomly selected patients using a cross-sectional study design (March-September, 2021), and samples were tested for the presence of ESCrE and CRE...
June 2024: IJID Reg
https://read.qxmd.com/read/38633709/cost-effectiveness-and-budget-impact-analysis-of-screening-and-preventive-interventions-for-cardiovascular-disease-in-myanmar-an-economic-modelling-study
#19
JOURNAL ARTICLE
Zin Mar Win, Wenhui Mao, Tom Traill, Zarni Lynn Kyaw, Pyone Yadanar Paing, Osondu Ogbuoji, Gavin Yamey
BACKGROUND: Cardiovascular diseases (CVD) remains a leading cause of mortality in Myanmar. Despite the burden, CVD preventive services receive low government and donor budgets, which has led to poor CVD outcomes. METHODS: We conducted a cost-effective analysis and a budget impact analysis on CVD prevention strategies recommended by the WHO. A Markov model was used to analyse the cost and quality-adjusted life year (QALY) from healthcare provider and societal perspectives...
July 2024: Lancet Reg Health Southeast Asia
https://read.qxmd.com/read/38633325/preclinical-validation-of-neowarm-a-low-cost-infant-warmer-and-carrier-device-to-ameliorate-induced-hypothermia-in-newborn-piglets-as-models-for-human-neonates
#20
JOURNAL ARTICLE
Nick D P Bluhm, Grant M Tomlin, Orlando S Hoilett, Elena A Lehner, Benjamin D Walters, Alyson S Pickering, Kevin Alessandro Bautista, Sherri L Bucher, Jacqueline C Linnes
INTRODUCTION: Approximately 1.5 million neonatal deaths occur among premature and small (low birthweight or small-for gestational age) neonates annually, with a disproportionate amount of this mortality occurring in low- and middle-income countries (LMICs). Hypothermia, the inability of newborns to regulate their body temperature, is common among prematurely born and small babies, and often underlies high rates of mortality in this population. In high-resource settings, incubators and radiant warmers are the gold standard for hypothermia, but this equipment is often scarce in LMICs...
2024: Frontiers in Pediatrics
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