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Diffusion of innovation

Laura Housden, Sabrina T Wong, Annette J Browne, Martin Dawes
In Canada, increasing numbers of people with chronic conditions have prompted calls for innovative approaches to delivering primary care. These approaches may include group medical visits (GMVs) and the introduction of nurse practitioners (NPs). We examined why NPs in the province of British Columbia were not using GMVs. This case study is part of a larger research project that examined the impact of GMVs with NPs for patients with chronic conditions. We completed open-ended interviews with seven NPs working in primary care...
October 24, 2016: Policy, Politics & Nursing Practice
M Sartori, S Pagani, A Ferrari, V Costa, V Carina, E Figallo, M C Maltarello, L Martini, M Fini, G Giavaresi
Current treatments for acute or degenerative chondral and osteochondral lesions are in need of improvement, as these types of injuries lead to disability and worsen the quality of life in a high percentage of patients. The aim of this study was to develop a new bi-layered scaffold for osteochondral tissue regeneration through a "biomimetic" and "bioinspired" approach. For chondral regeneration, the scaffold was realized with an organic compound (type I collagen), while for the regeneration of the subchondral layer, bioactive magnesium-doped hydroxyapatite (Mg/HA) crystals were co-precipitated with the organic component of the scaffold...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
Edward Johnston, Hayley Pye, Elisenda Bonet-Carne, Eleftheria Panagiotaki, Dominic Patel, Myria Galazi, Susan Heavey, Lina Carmona, Alexander Freeman, Giorgia Trevisan, Clare Allen, Alexander Kirkham, Keith Burling, Nicola Stevens, David Hawkes, Mark Emberton, Caroline Moore, Hashim U Ahmed, David Atkinson, Manuel Rodriguez-Justo, Tony Ng, Daniel Alexander, Hayley Whitaker, Shonit Punwani
BACKGROUND: Whilst multi-parametric magnetic resonance imaging (mp-MRI) has been a significant advance in the diagnosis of prostate cancer, scanning all patients with elevated prostate specific antigen (PSA) levels is considered too costly for widespread National Health Service (NHS) use, as the predictive value of PSA levels for significant disease is poor. Despite the fact that novel blood and urine tests are available which may predict aggressive disease better than PSA, they are not routinely employed due to a lack of clinical validity studies...
October 21, 2016: BMC Cancer
Roberto Eduardo Schneiders, Ricardo de March Ronsoni, Flávia Mori Sarti, Marcelo Eidi Nita, Ediane de Assis Bastos, Ivan Ricardo Zimmermann, Fernando Fagundes Ferreira
Budget Impact Analyses require a set of essential information on health technology innovation, including expected rates of adoption. There is an absence of studies investigating trends, magnitude of budgetary effects and determinants of diffusion rates for health technology innovations worldwide during the last decades. The present study proposes a pilot assessment on main determinants influencing diffusion rates of pharmaceutical innovations within the Brazilian Unified National Health System (SUS). Data from the Brazilian Health Informatics Department (DATASUS) was gathered to establish the main determinants of diffusion rates of health technology innovations in Brazil, specifically referring to pharmaceutical innovations incorporated in the Brazilian Program for Specialized Pharmaceutical Services (CEAF) at SUS...
October 10, 2016: Cadernos de Saúde Pública
Kathleen Charlebois, Nicole Palmour, Bartha Maria Knoppers
This study aims to understand the influence of the ethical and legal issues on cloud computing adoption in the field of genomics research. To do so, we adapted Diffusion of Innovation (DoI) theory to enable understanding of how key stakeholders manage the various ethical and legal issues they encounter when adopting cloud computing. Twenty semi-structured interviews were conducted with genomics researchers, patient advocates and cloud service providers. Thematic analysis generated five major themes: 1) Getting comfortable with cloud computing; 2) Weighing the advantages and the risks of cloud computing; 3) Reconciling cloud computing with data privacy; 4) Maintaining trust and 5) Anticipating the cloud by creating the conditions for cloud adoption...
2016: PloS One
Craig W Trumbo, Raquel Harper
We examine differences between college students and non-students with respect to orientation toward e-cigarettes. Participants were U.S. adults 18-24 (465 students, 409 non-students). Data collection employed an online survey by GfK Custom Research. Smoking, vaping, and use of alternate tobacco were assessed, as were variables from the Theory of Reasoned Action and Diffusion of Innovations. This study showed that smoking status largely explains use and orientation toward electronic cigarettes among both students and non-students, with differences attributable to higher smoking rates among non-students...
August 19, 2016: Journal of Public Health Research
Shivani M Reddy, Danielle E Rose, James F Burgess, Martin P Charns, Elizabeth M Yano
BACKGROUND: Increasing numbers of women veterans present an organizational challenge to a health care system that historically has served men. Women veterans require comprehensive women's health services traditionally not provided by the Veterans Health Administration. OBJECTIVE: Examine the association of organizational factors and adoption of comprehensive women's health care. STUDY DESIGN: Cross-sectional analysis of the 2007 Veterans Health Administration National Survey of Women Veterans Health Programs and Practices...
October 13, 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
Megan Simmons, Lucia Guerra-Reyes, Beth Meyerson, Kristin Adams, Stephanie Sanders
BACKGROUND: In 2014, the Centers for Disease Control and Prevention and the Office of Population Affairs released a document entitled Providing Quality Family Planning Services (QFP), which outlined recommendations for delivery of family planning services using a client-centered approach. These aimed to standardize service provision and address numerous reproductive health challenges. To date, little is known about QFP implementation or the factors influencing its adoption by clinicians...
October 13, 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
Teresa Graziano, Angela Amoruso, Stefania Nicola, Francesca Deidda, Serena Allesina, Marco Pane, Pietro Piffanelli, Francesco Strozzi, Luca Mogna, Mario Del Piano
GOALS: The aim of the study was to unequivocally demonstrate the nontransmissibility of the genes mediating the resistance of the strain Bifidobacterium longum W11 (LMG P-21586) to rifaximin. BACKGROUND: Most antibiotic treatments can induce unfavorable side effects such as antibiotic-associated diarrhea, which is largely attributable to the disruption of the intestinal microbiota. The parallel intake of probiotic bacteria might reduce these events, even if with generally very poor results...
November 2016: Journal of Clinical Gastroenterology
Luca Mogna, Francesca Deidda, Stefania Nicola, Angela Amoruso, Mario Del Piano, Giovanni Mogna
GOALS: To determine the in vitro antimicrobial activity of selected Lactobacillus strains isolated from the feces of healthy humans against Klebsiella pneumoniae. BACKGROUND: Klebsiella is ubiquitous in nature and may colonize the skin, the pharynx, or the gastrointestinal tract of humans. Despite the widespread use of antibiotic molecules with a broad spectrum in hospitalized patients, an increased overall load of klebsiellae as well as the subsequent development of multidrug-resistant strains able to synthesize extended-spectrum beta-lactamase have been registered...
November 2016: Journal of Clinical Gastroenterology
Janet A Levey
AIM: The purpose of the study was to examine the characteristics and relationships of nurse educators' teaching practices, knowledge, support, and willingness to adopt inclusive teaching strategies (WillAdITS). BACKGROUND: Adopting more inclusive teaching strategies based on universal design for instruction is an innovative way for educators to reach today's diverse student body. However, the pedagogy has not diffused into nursing education. METHOD: Descriptive statistics and hierarchical multiple regression were used for analyzing data from 311 nurse educators in prelicensure and RN to BSN programs...
July 2016: Nursing Education Perspectives
Suneetha Kadiyala, Emily H Morgan, Shruthi Cyriac, Amy Margolies, Terry Roopnaraine
Successful integration of nutrition interventions into large-scale development programmes from nutrition-relevant sectors, such as agriculture, can address critical underlying determinants of undernutrition and enhance the coverage and effectiveness of on-going nutrition-specific activities. However, evidence on how this can be done is limited. This study examines the feasibility of delivering maternal, infant, and young child nutrition behaviour change communication through an innovative agricultural extension programme serving nutritionally vulnerable groups in rural India...
2016: PloS One
Ahmed Ali Elsayed, Akira Satou, Ahmed E Eladl, Seiichi Kato, Shigeo Nakamura, Naoko Asano
AIMS: To report the clinicopathologic features of EBV-positive (EBV(+) ) grey zone lymphoma (GZL) with features intermediate between diffuse large B-cell lymphoma (DLBCL) and classical Hodgkin lymphoma (CHL). METHODS AND RESULTS: We report the clinicopathologic features of 14 cases of EBV(+) GZL in Japan. The control group included 173 cases of EBV(+) CHL and 64 cases of EBV(+) DLBCL of the elderly (polymorphous type). Patients included 10 men and 4 women with a median age of 62 years...
October 13, 2016: Histopathology
Georgina Maffey, R Justin Irvine, Mark Reed, René van der Wal
Monitoring is one of the key tools employed to help understand the condition of the natural environment and inform the development of appropriate management actions. While international conventions encourage the use of standardised methods, the link between the information monitoring provides and local management needs is frequently overlooked. This problem is further exacerbated when monitoring is employed in areas where there are divergent interests among stakeholders in land use and management. Such problems are found in the management of wild deer across Scotland, where monitoring, in the form of habitat impact assessments, have been introduced as an innovation in sustainable deer management...
October 2, 2016: Journal of Environmental Management
Sylvain Alem, Clint J Perry, Xingfu Zhu, Olli J Loukola, Thomas Ingraham, Eirik Søvik, Lars Chittka
Social insects make elaborate use of simple mechanisms to achieve seemingly complex behavior and may thus provide a unique resource to discover the basic cognitive elements required for culture, i.e., group-specific behaviors that spread from "innovators" to others in the group via social learning. We first explored whether bumblebees can learn a nonnatural object manipulation task by using string pulling to access a reward that was presented out of reach. Only a small minority "innovated" and solved the task spontaneously, but most bees were able to learn to pull a string when trained in a stepwise manner...
October 2016: PLoS Biology
Valeria Romanazzi, Silvia Bonetta, Stefania Fornasero, Margherita De Ceglia, Giorgio Gilli, Deborah Traversi
Wastewater treatment plants (WWTP) are an important source of surface water contamination by enteric pathogens, affecting the role of environmental water as a microbial reservoir. We describe the release to the environment of certain anaerobes of human and environmental concern. The work was focused on emerging microbial targets. They are tracing, by RT-qPCR, on WWTP effluents, both liquid and solid, when an anaerobic digestion step is included. The focus is placed on Clostridium spp. with the specific quantification of Clostridium perfringens, as typical bioindicator, and Clostridium difficile, as emerging pathogen not only confined into nosocomial infection...
September 30, 2016: Journal of Environmental Management
Liwen Mu, Tuo Ji, Long Chen, Nitin Mehra, Yijun Shi, Jiahua Zhu
Phonon transfer is greatly scattered in traditional polymer composites due to the unpaired phonon frequency at polymer/filler interface. A key innovation of this work is to build continuous crystal network by self-organization and utilize it as "thermal highway" that circumvents the long-existing interfacial thermal barrier issue in traditional composites. By tuning the molecular diffusion rate of dicarboxylic acids (oxalic acid, malonic acid and succinic acid), different crystal structures including skeletal, dendrite, diffusion limited aggregates and spherulite were synthesized in PVA film...
October 3, 2016: ACS Applied Materials & Interfaces
Savannah C Partridge, Noam Nissan, Habib Rahbar, Averi E Kitsch, Eric E Sigmund
: Diffusion-weighted MRI (DWI) holds potential to improve the detection and biological characterization of breast cancer. DWI is increasingly being incorporated into breast MRI protocols to address some of the shortcomings of routine clinical breast MRI. Potential benefits include improved differentiation of benign and malignant breast lesions, assessment and prediction of therapeutic efficacy, and noncontrast detection of breast cancer. The breast presents a unique imaging environment with significant physiologic and inter-subject variations, as well as specific challenges to achieving reliable high quality diffusion-weighted MR images...
September 30, 2016: Journal of Magnetic Resonance Imaging: JMRI
Ilaria Bassani, Panagiotis G Kougias, Irini Angelidaki
Biological biogas upgrading coupling CO2 with external H2 to form biomethane opens new avenues for sustainable biofuel production. For developing this technology, efficient H2 to liquid transfer is fundamental. This study proposes an innovative setup for in-situ biogas upgrading converting the CO2 in the biogas into CH4, via hydrogenotrophic methanogenesis. The setup consisted of a granular reactor connected to a separate chamber, where H2 was injected. Different packing materials (rashig rings and alumina ceramic sponge) were tested to increase gas-liquid mass transfer...
December 2016: Bioresource Technology
David Haas
The article explores the impact of the diffusion of new methods of production on output and employment growth and income distribution within a Classical one-sector framework. Disequilibrium paths are studied analytically and in terms of simulations. Diffusion by differential growth affects aggregate dynamics through several channels. The analysis reveals the non-steady nature of economic change and shows that the adaptation pattern depends both on the innovation's factor-saving bias and on the extent of the bias, which determines the strength of the selection pressure on non-innovators...
November 2015: Metroeconomica
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