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Fame study

Jung Ah Choi, Dong-Yeon Kim, Yeong Hwan Seo, Jong-In Han
In this study, Chlorella sorokiniana was successfully cultivated in the recycled medium whose nitrogen was supplied directly from the coagulant, Fe(NO3)3. With a dosage of 0.80g/L, harvesting efficiency of 95% could be achieved. What is more, this amount of nitrate in the coagulant was enough to fully support the growth of C. sorokiniana during the 8day cultivation period, almost as much as the initial nitrogen content in the BG11 culture medium. Other nutrients had to be supplemented, however, with at least 50% amount as in the BG11 recipe...
September 30, 2016: Bioresource Technology
Kandikere R Sridhar, Dorathy D Anita, Sudeep D Ghate
This study compares the composition of fatty acid methyl esters (FAMEs) in seeds of Sesbania speciosa (dry and mature) after processing (uncooked and cooked) and extraction (hot and cold). Among PUFA, oleic, linoleic and linolenic acids were common to uncooked and cooked dry seeds which were high on cold extraction. Only two fatty acid ratios were favorable in hot extraction [(C14:0 + C15:0 + (C16:0 / C18:0) and C18:1 / C18:2]. Cold extraction yielded docosahexaenoic acid in uncooked as well as cooked dry seeds and all fatty acid ratios were nutritionally favorable...
October 3, 2016: Recent Patents on Food, Nutrition & Agriculture
Bing Sun, Yuxin Bai, Liyuan Zhang, Linlin Gong, Xiaoyu Qi, Huizhen Li, Faming Wang, Xinming Chi, Yulin Jiang, Shujuan Shao
Lung cancer remains the leading cancer killer around the world. It's crucial to identify newer mechanism-based targets to effectively manage lung cancer. Annexin A5 (ANXA5) is a protein kinase C inhibitory protein and calcium dependent phospholipid-binding protein, which may act as an endogenous regulator of various pathophysiological processes. However, its molecular mechanism in lung cancer remains poorly understood. This study was designed to determine the mechanism of ANXA5 in lung cancer with a hope to obtain useful information to provide a new therapeutic target...
2016: PloS One
Christian Wiese, Eva Große Maestrup, Fabian Galla, Dirk Schepmann, Achim Hiller, Steffen Fischer, Friedrich-Alexander Ludwig, Winnie Deuther-Conrad, Cornelius K Donat, Peter Brust, Lars Büter, Uwe Karst, Bernhard Wünsch
The imaging of σ1 receptors in the brain by fluorinated radiotracers will be used for the validation of σ1 receptors as drug targets as well as for differential diagnosis of diseases in the central nervous system. The biotransformation of four homologous fluorinated PET tracers 1'-benzyl-3-(ω-fluoromethyl to ω-fluorobutyl)-3H-spiro[2]benzofuran-1,4'-piperidine] ([(18) F]1-4) was investigated. In silico studies using fast metabolizer (FAME) software, electrochemical oxidations, in vitro studies with rat liver microsomes, and in vivo metabolism studies after application of the PET tracers [(18) F]1-4 to mice were performed...
September 28, 2016: ChemMedChem
Asha Rani, Subhadeep Roy, Manjari Singh, Uma Devi, Rajnish K Yadav, Swetlana Gautam, Jitendra K Rawat, Mohd Nazam Ansari, Abdulaziz S Saeedan, Anand Prakash, Gaurav Kaithwas
This study was undertaken to investigate the effect of α-chymotrypsin on methyl nitrosourea (MNU) induced mammary gland carcinoma in albino wistar rats. Animals were randomized into four groups (six animals in each). Group I (sham control 0.9 % normal saline p.o.); Group II (toxic control, MNU 47 mg/kg, i.v.); Group III (α-chymotrypsin, 5 mg/kg, p.o.); Group IV (α-chymotrypsin, 10 mg/kg p.o.). Toxicity was induced by single i.v. injection of MNU followed by α-chymotrypsin supplementation therapy for 100 days...
October 2016: Inflammopharmacology
Pasquale Striano, Federico Zara
The term 'cortical tremor' was first introduced by Ikeda and colleagues to indicate a postural and action-induced shivering movement of the hands which mimics essential tremor, but presents with the electrophysiological findings of cortical reflex myoclonus. The association between autosomal dominant cortical tremor, myoclonus and epilepsy (ADCME) was first recognized in Japanese families and is now increasingly reported worldwide, although it is described using different acronyms (BAFME, FAME, FEME, FCTE and others)...
September 1, 2016: Epileptic Disorders: International Epilepsy Journal with Videotape
Jechan Lee, Yiu Fai Tsang, Jong-Min Jung, Jeong-Ik Oh, Hyung-Wook Kim, Eilhann E Kwon
In-situ production of fatty acid methyl esters from swine fat via thermally induced pseudo-catalytic transesterification on silica was investigated in this study. Instead of methanol, dimethyl carbonate (DMC) was used as acyl acceptor to achieve environmental benefits and economic viability. Thermo-gravimetric analysis of swine fat reveals that swine fat contains 19.57wt.% of water and impurities. Moreover, the fatty acid profiles obtained under various conditions (extracted swine oil+methanol+NaOH, extracted swine oil+DMC+pseudo-catalytic, and swine fat+DMC+pseudo-catalytic) were compared...
November 2016: Bioresource Technology
Marco Cascella
Professor Giuseppe Moscati (1880-1927) was canonized by the Catholic Church in 1987. This act recognized the extraordinary qualities of a doctor who, considering his work as a "sublime mission", dedicated his life to helping the sick. The fame of the "Holy doctor" or "doctor of the poor", as people called him, was soon widespread and, immediately after his death, made him the subject of several biographies. These treatises, mainly written by religious hagiographers, have little analyzed Moscati as a doctor and scientist, or, in rare cases, privileged the description of his medical career, touching only marginally salient aspects of his work as a scientist and researcher...
August 2016: Acta Medico-historica Adriatica: AMHA
Haiming Huang, Peng Zhang, Jing Xiao, Dean Xiao, Faming Gao
In this study, the decomposition of struvite by ultrasound stripping and the recycle use of the decomposition product for the treatment of landfill leachate were investigated. The results indicated that when the decomposition of struvite by ultrasound stripping was performed at 55°C for 40min, the ammonium in the struvite could be almost completely eliminated from the solution system. The characterization analysis showed that magnesium phosphate and the dissolved phosphate ions were the main active derivatives...
August 12, 2016: Ultrasonics Sonochemistry
Zhaoyuan Peng, Jie Xiang, Zhi He, Ting Zhang, Lijuan Xu, Bota Cui, Pan Li, Guangming Huang, Guozhong Ji, Yongzhan Nie, Kaichun Wu, Daiming Fan, Faming Zhang
BACKGROUND AND STUDY AIMS: Placement of a tube through the anus into the cecum has not yet been established as a method of administering whole-colonic treatment. The aim of this study was to evaluate the safety, feasibility, and value of transendoscopic enteral tubing (TET) for fecal microbiota transplantation (FMT) through the colon. PATIENTS AND METHODS: A prospective observational study was performed of FMT using a new colonic TET technique. Under endoscopic guidance, a TET tube was affixed to the cecum with clips...
June 2016: Endoscopy International Open
Kylie Eddy, Zoe Jordan, Matthew Stephenson
BACKGROUND: Teamwork is seen as an important element of patient care in acute hospital settings. The complexity of the journey of care for patients highlights the need for health professionals to collaborate and communicate clearly with each other. Health organizations in western countries are committed to improving patient safety through education of staff and teamwork education programs have been integral to this focus. There are no current systematic reviews of the experience of health professionals who participate in teamwork education in acute hospital settings...
April 2016: JBI Database of Systematic Reviews and Implementation Reports
Ankita Sati, Sushil Chandra Sati, Nitin Sati, O P Sati
Natural fats and dietary oils are chief source of fatty acids and are well known to have antimicrobial activities against various microbes. The chemical composition and antimicrobial activities of fatty acids from fruits of white Oak (Quercus leucotrichophora) are yet unexplored and therefore the present study for the first time determines the fatty acid composition, and the antibacterial and antifungal activities of fatty acid methyl esters (FAME) of the white Oak plant found along the Himalayan region of Uttarakhand, India...
August 8, 2016: Natural Product Research
Ye Wang, Faming Jiang, Xiaobo Tan, Panwen Tian
Computed tomography-guided percutaneous transthoracic needle biopsy (PTNB) is used for identifying paramediastinal lung lesions that cannot be diagnosed by bronchoscopy, but the diagnostic performance and complication rate are unreported.This retrospective study was approved by the institutional review board committee. A total of 1484 patients who underwent PTNB between April 2012 and April 2015 were enrolled. The cohort was divided into a paramediastinal (n = 195) and a nonparamediastinal group (n = 1289) based on lesion location...
August 2016: Medicine (Baltimore)
Dawn A Skelton, Cathy Bailey, Denise Howel, Mima Cattan, Vincent Deary, Dot Coe, Lex D de Jong, Sheena Gawler, Joanne Gray, Rosy Lampitt, Jennifer Wilkinson, Nicola Adams
INTRODUCTION: In the UK, 1 in 5 people aged 75 and over live with sight loss. Visually impaired older people (VIOP) have an above average incidence of falls and 1.3-1.9 times more likely to experience hip fractures, than the general population. Older people with eye diseases are ∼3 times more likely than those with good vision, to limit activities due to fear of falling. This feasibility study aims to adapt the group-based Falls Management Exercise (FaME) programme to the needs of VIOP and carry out an external pilot trial to inform the design of a future definitive randomised controlled trial...
2016: BMJ Open
Lijuan Xu, Ting Zhang, Bota Cui, Zhi He, Jie Xiang, Chuyan Long, Zhaoyuan Peng, Pan Li, Guangming Huang, Guozhong Ji, Faming Zhang
Few studies have been conducted on the attitudes of patients seeking fecal microbiota transplantation (FMT). This study aimed to investigate the reasons for patients with Crohn's disease (CD) seeking FMT and their attitude changes after FMT.In this prospective study, all included patients were diagnosed with CD for at least 6 months and intended to receive FMT. A questionnaire was designed to investigate the history of medical visits and patients' attitudes toward FMT. Only refractory patients who failed to clinically respond to previous treatment were selected for undergoing FMT...
July 2016: Medicine (Baltimore)
Shuyun Wu, Mohamad H Yassine, Makram T Suidan, Albert D Venosa
Biotransformation of soybean biodiesel and its biodiesel/petrodiesel blends were investigated under sulfate-reducing conditions. Three blends of biodiesel, B100, B50, and B0, were treated using microbial cultures pre-acclimated to B100 (biodiesel only) and B80 (80% biodiesel and 20% petrodiesel). Results indicate that the biodiesel could be effectively biodegraded in the presence or absence of petrodiesel, whereas petrodiesel could not be biodegraded at all under sulfate-reducing conditions. The kinetics of biodegradation of individual Fatty Acid Methyl Ester (FAME) compounds and their accompanying sulfate-reduction rates were studied using a serum bottle test...
October 2016: Chemosphere
Rashid Rasheed, Saleha Tariq, Syed Ali Raza Naqvi, Syed Jawad Hussain Gillani, Faheem Askari Rizvi, Muhammad Sajid, Shahid Rasheed
The aim of this study is to develop (177) Lu-5-Flourouracil as a potential cancer therapeutic radiopharmaceutical. 5-Flourouracil (5-FU) is widely accepted as an anticancer drug of broad spectrum fame. The labeling of 5-FU was carried out at different set of experimental conditions using high specific activity of (177) LuCl3 . The optimum conditions for maximum radiochemical yield was set: 5-FU (5 mg), (177) LuCl3 (185 MBq), diethylenetriaminepentaacetic acid (10 µg), reaction volume (2 mL), pH (5...
August 2016: Journal of Labelled Compounds & Radiopharmaceuticals
S Yurchenko, A Sats, V Poikalainen, A Karus
Bovine colostrum is potentially valuable source of essential fatty acids (FAs), but so far only few studies have made the effort to estimate FA composition of this potential resource. The aim of current research was to fill this gap with selecting and validating an accurate procedure for the analysis of the composition of the FAs in bovine colostrum. We used colostrum samples of Holstein-Friesian cattle from Märja experimental farm as a test material. The validated method includes derivatization, in which FAs are sent through esterification with the acidic catalyst boron trifluoride...
December 1, 2016: Food Chemistry
Zulfiqar Ali Mirani, Shagufta Naz, Fouzia Khan, Mubashir Aziz, Asadullah, Muhammad Naseem Khan, Seema Ismat Khan
Present study is based on 20 methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered from different food items. These isolates were identified on the basis of colony morphology, Gram staining and growth on different selective and differential media. Studies on 16S RNA and positive reactions on DNase agar and Prolex Latex Agglutination system confirm it as Staphylococcus aureus. Oxacillin susceptibility testing and PCR with mecA gene-specific primer results showed that these isolates are MRSA-carrying mecA gene that belongs to SCCmecA type IV and also harbor agr type II...
June 29, 2016: Journal of Antibiotics
Ting Zhang, Bota Cui, Pan Li, Zhi He, Chuyan Long, Lu Wei, Zhaoyuan Peng, Guozhong Ji, Faming Zhang
OBJECTIVE: There were no reports on predicting long-term efficacy of fecal microbiota transplantation (FMT) for ulcerative colitis (UC). This study aimed to detect short-term changes of cytokines and C-reactive protein (CRP) in patients with UC undergoing FMT, and to evaluate the predictive value of CRP and cytokines for the long-term efficacy of FMT. METHODS: Nineteen patients with moderate to severe UC (Mayo score ≥ 6) were treated with single fresh FMT through mid-gut...
2016: PloS One
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