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https://www.readbyqxmd.com/read/28210982/new-and-uncommon-fatty-acids-in-lipids-of-deep-sea-foraminifera
#1
Vladimir I Kharlamenko, Vasily I Svetashev, Tatyana S Tarasova
Fatty acids (FA) of agglutinating foraminifera of two genera, Bathysiphon and Rhabdammina, collected from a depth of 3307-3377 m in the Kuril Basin, Sea of Okhotsk, and adjacent deep-sea waters of the Pacific Ocean, were analyzed. In lipids of two Bathysiphon species, in addition to common FA typical for marine organisms, the uncommon ∆4 and ∆7 monoenoic acids and ∆4,7-dienoic acid were found in noticeable amounts. FA of two Rhabdammina species included also such uncommon acids as ∆5,8,11,14-21:4, ∆5,8,11,14-22:4, and ∆5,8,11,14-23:4, which are homologues to arachidonic acid...
February 16, 2017: Lipids
https://www.readbyqxmd.com/read/28196083/cacybp-sip-promotes-the-proliferation-of-colon-cancer-cells
#2
Huihong Zhai, Yongquan Shi, Xiong Chen, Jun Wang, Yuanyuan Lu, Faming Zhang, Zhengxiong Liu, Ting Lei, Daiming Fan
CacyBP/SIP is a component of the ubiquitin pathway and is overexpressed in several transformed tumor tissues, including colon cancer, which is one of the most common cancers worldwide. It is unknown whether CacyBP/SIP promotes the proliferation of colon cancer cells. This study examined the expression level, subcellular localization, and binding activity of CacyBP/SIP in human colon cancer cells in the presence and absence of the hormone gastrin. We found that CacyBP/SIP was expressed in a high percentage of colon cancer cells, but not in normal colonic surface epithelium...
2017: PloS One
https://www.readbyqxmd.com/read/28186590/-mutational-analysis-of-slc22a5-gene-in-eight-patients-with-systemic-primary-carnitine-deficiency
#3
Yiming Lin, Weihua Lin, Ke Yu, Faming Zheng, Zhenzhu Zheng, Qingliu Fu
OBJECTIVE: To investigate the mutations of SLC22A5 gene in patients with systemic primary carnitine deficiency (CDSP). METHODS: High liquid chromatography tandem mass spectrometry (HPLC/MS/MS) was applied to screen congenital genetic metabolic disease and eight patients with CDSP were diagnosed among 77 511 samples. The SLC22A5 gene mutation was detected using massarray technology and sanger sequencing. Using SIFT and PolyPhen-2 to predict the function of protein for novel variations...
February 10, 2017: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/28169024/a-sustainable-use-of-ricotta-cheese-whey-for-microbial-biodiesel-production
#4
Eleonora Carota, Silvia Crognale, Alessandro D'Annibale, Anna Maria Gallo, Silvia Rita Stazi, Maurizio Petruccioli
The increasing demand of plant oils for biodiesel production has highlighted the need for alternative strategies based either on non-food crops or agro-industrial wastes that do not compete with food and feed production. In this context, the combined use of wastewater and oleaginous microorganisms could be a valuable production option. Ricotta cheese whey (RCW), one of the major byproducts of the dairy industry, is produced in very high and steadily increasing amounts and, due to its high organic load, its disposal is cost-prohibitive...
February 3, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28156133/phycoremediation-of-municipal-wastewater-by-microalgae-to-produce-biofuel
#5
Amit Kumar Singh, Nikunj Sharma, Humaira Farooqi, Malik Zainul Abdin, Thomas Mock, Shashi Kumar
Municipal wastewater (WW), if not properly remediated, poses a threat to the environment and human health by carrying significant loads of nutrients and pathogens. These contaminants pollute rivers, lakes and natural reservoirs where they cause eutrophication and pathogen-mediated diseases. However, the high nutrient content of WW makes it an ideal environment for remediation with microalgae that require high nutrient concentrations for growth and are not susceptible to toxins and pathogens. Given that an appropriate algal strain is used for remediation, the incurred biomass can be refined for the production of biofuel...
February 3, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28155998/lipids-of-rhodotorula-mucilaginosa-iipl32-with-biodiesel-potential-oil-yield-fatty-acid-profile-fuel-properties
#6
Mahesh Khot, Debashish Ghosh
This study analyzes the single cell oil (SCO), fatty acid profile, and biodiesel fuel properties of the yeast Rhodotorula mucilaginosa IIPL32 grown on the pentose fraction of acid pre-treated sugarcane bagasse as a carbon source. The yeast biomass from nitrogen limiting culture conditions (15.3 g L(-1) ) was able to give the SCO yield of 0.17 g g(-1) of xylose consumed. Acid digestion, cryo-pulverization, direct in situ transesterification, and microwave assisted techniques were evaluated in comparison to the Soxhlet extraction for the total intracellular yeast lipid recovery...
February 3, 2017: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/28121944/progression-rate-of-ankylosing-spondylitis-in-patients-with-undifferentiated-spondyloarthritis-a-systematic-review-and-meta-analysis
#7
Qing Xia, Dazhi Fan, Xiao Yang, Xiaona Li, Xu Zhang, Mengmeng Wang, Shengqian Xu, Faming Pan
BACKGROUND: The idea that undifferentiated spondyloarthritis (uSpA) represents the early undifferentiated stage of ankylosing spondylitis (AS) and other well-defined SpA subtypes is well known. The gist of this study is to assess the rate estimate of patients with uSpA evolved to AS during long-term follow-up. METHODS: A systematic search was implemented to identify pertinent articles. The primary outcome was the rate estimate that patients with uSpA fulfilling the diagnosis of AS according to the modified New York criteria during follow-up...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28118388/ftir-spectroscopy-for-evaluation-and-monitoring-of-lipid-extraction-efficiency-for-oleaginous-fungi
#8
Kristin Forfang, Boris Zimmermann, Gergely Kosa, Achim Kohler, Volha Shapaval
To assess whether Fourier Transform Infrared (FTIR) spectroscopy could be used to evaluate and monitor lipid extraction processes, the extraction methods of Folch, Bligh and Lewis were used. Biomass of the oleaginous fungi Mucor circinelloides and Mortierella alpina were employed as lipid-rich material for the lipid extraction. The presence of lipids was determined by recording infrared spectra of all components in the lipid extraction procedure, such as the biomass before and after extraction, the water and extract phases...
2017: PloS One
https://www.readbyqxmd.com/read/28115475/serum-trypsinogen-levels-in-type-1-diabetes
#9
Xia Li, Martha Campbell-Thompson, Clive H Wasserfall, Kieran McGrail, Amanda Posgai, Andrew R Schultz, Todd M Brusko, Jonathan Shuster, Faming Liang, Andrew Muir, Desmond Schatz, Michael J Haller, Mark A Atkinson
OBJECTIVE: The pancreas in type 1 diabetes exhibits decreased size (weight/volume) and abnormal exocrine morphology. Serum trypsinogen levels are an established marker of pancreatic exocrine function. As such, we hypothesized that trypsinogen levels may be reduced in patients with pre-type 1 diabetes and type 1 diabetes compared with healthy control subjects. RESEARCH DESIGN AND METHODS: Serum trypsinogen levels were determined in 100 persons with type 1 diabetes (72 new-onset, 28 established), 99 autoantibody-positive (AAb+) subjects at varying levels of risk for developing this disease, 87 AAb-negative (AAb-) control subjects, 91 AAb- relatives with type 1 diabetes, and 18 patients with type 2 diabetes...
January 23, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28111167/associations-of-killer-cell-immunoglobulin-like-receptors-with-acute-myeloid-leukemia-in-chinese-populations
#10
Sudan Tao, Yanmin He, Lina Dong, Junjun He, Nanying Chen, Wei Wang, Zhedong Han, Wei Zhang, Ji He, Faming Zhu
Many studies have investigated the relationship between KIR, HLA and acute myeloid leukemia (AML), but the results were different in different laboratories, and the data in Chinese population were limited. In this study, the distribution of KIR gene, KIR genotypes, HLA-C groups, HLA-Bw4, and KIR-HLA interaction from 273 healthy participants and 253 AML patients (M0-M6) in southern Chinese Han were determined to investigate the relationships among KIR, HLA and AML. The results showed that the frequencies of 2DS4del in M5 patients were significantly higher than those of the controls (65...
January 20, 2017: Human Immunology
https://www.readbyqxmd.com/read/28107709/quantification-of-fatty-acids-in-the-muscle-of-antarctic-fish-trematomus-bernacchii-by-gas-chromatography-mass-spectrometry-optimization-of-the-analytical-methodology
#11
C Truzzi, S Illuminati, A Annibaldi, M Antonucci, G Scarponi
This work presents data on the quantification of fatty acids (FAs, in terms of mass unit per tissue weight) in the muscle of Trematomus bernacchii, a key species in Antarctica, often used as bioindicator for contamination studies. Modifications in fatty acids content should be considered a useful biomarker to study how contaminants affect Antarctic biota. Until now, very few studies quantified fatty acids of muscle of T. bernacchii, and only as percentage of a single fatty acid on total lipids. To perform the quantification of fatty acids, we used an analytical method based on a fast microwave-assisted extraction of lipids from a lyophilized sample, a base-catalyzed trans-esterification of lipid extract to obtain Fatty Acids Methyl Esters (FAMEs), and a separation and identification of FAMEs by gas chromatography-mass spectrometry...
December 31, 2016: Chemosphere
https://www.readbyqxmd.com/read/28106676/a-remarkable-journey-why-the-magnet-recognition-program%C3%A2-continues-to-resonate-today
#12
Muriel Poulin
It has been more than 30 years since an enterprising team of American Academy of Nursing researchers unearthed groundbreaking findings that led to the creation of the American Nurses Credentialing Center's Magnet Recognition Program®. Dr Muriel Poulin, EdD, RN, FAAN, a coauthor of the original Magnet® hospital study, recalls how she and her colleagues opted to take their research in a different direction and address pressing questions that spoke directly to the needs and desires of staff nurses. She shares her thoughts on why the Magnet Recognition Program continues to resonate today...
February 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28092732/enhancement-of-lipid-productivity-by-adopting-multi-stage-continuous-cultivation-strategy-in-nannochloropsis-gaditana
#13
Min-Gyu Sung, Bongsoo Lee, Chul Woong Kim, Kibok Nam, Yong Keun Chang
In the present study, a novel process-based cultivation system was designed to improve lipid productivity of Nannochloropsis gaditana, an oleaginous microalga that has high potential for biofuel production. Specifically, four flat-panel photobioreactors were connected in series, and this system was subjected to continuous chemostat cultivation by feeding fresh medium to the first reactor at dilution rates of 0.028 and 0.056day(-1), which were determined based on Monod kinetics. The results show that the serially connected photobioreactor system achieved 20...
April 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28068642/optimization-of-photocatalytic-degradation-of-biodiesel-using-tio2-h2o2-by-experimental-design
#14
Elizangela Ambrosio, Diego L Lucca, Maicon H B Garcia, Maísa T F de Souza, Thábata K F de S Freitas, Renata P de Souza, Jesuí V Visentainer, Juliana C Garcia
This study reports on the investigation of the photodegradation of biodiesel (B100) in contact with water using TiO2/H2O2. The TiO2 was characterized by X-ray diffraction analysis (XRD), pH point of zero charge (pHpzc) and textural analysis. The results of the experiments were fitted to a quadratic polynomial model developed using response surface methodology (RSM) to optimize the parameters. Using the three factors, three levels, and the Box-Behnken design of experiment technique, 15 sets of experiments were designed considering the effective ranges of the influential parameters...
January 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28049491/fenofibrate-in-the-management-of-abdominal-aortic-aneurysm-fame-study-protocol-for-a-randomised-controlled-trial
#15
Sophie E Rowbotham, Doug Cavaye, Rene Jaeggi, Jason S Jenkins, Corey S Moran, Joseph V Moxon, Jenna L Pinchbeck, Frank Quigley, Christopher M Reid, Jonathan Golledge
BACKGROUND: Abdominal aortic aneurysm (AAA) is a slowly progressive destructive process of the main abdominal artery. Experimental studies indicate that fibrates exert beneficial effects on AAAs by mechanisms involving both serum lipid modification and favourable changes to the AAA wall. METHODS/DESIGN: Fenofibrate in the management of AbdoMinal aortic anEurysm (FAME) is a multicentre, randomised, double-blind, placebo-controlled clinical trial to assess the effect of orally administered therapy with fenofibrate on key pathological markers of AAA in patients undergoing open AAA repair...
January 4, 2017: Trials
https://www.readbyqxmd.com/read/28048283/we-h-204-03-part-2-history-and-archives-resources-at-aip-for-aapm-and-its-members
#16
M Mueller
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047523/we-h-204-00-history-committee-symposium
#17
Michael Gossman
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046866/we-h-204-01-william-d-coolidge-inventor-of-the-modern-x-ray-tube
#18
D Allard
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046206/we-h-204-02-part-1-history-and-archives-resources-at-aip-for-aapm-and-its-members
#19
G Good
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27984616/-study-of-the-molecular-basis-of-an-individual-with-aw43-subtype-of-the-abo-blood-group
#20
Danfei Deng, Genjie Lu, Xiaozhe Hong, Xianguo Xu, Ji He, Faming Zhu
OBJECTIVE: To explore the molecular basis of an individual with A subtype of the ABO blood group. METHODS: The ABO antigen and serum antibody of the proband and his parents and sister were detected by a serological method. The whole coding regions of the ABO gene were amplified by PCR and subjected to bidirectional sequencing. RESULTS: Red blood cells of the proband showed mixed field agglutination with anti-A but did not agglutinate with anti-B, and his serum did not agglutinate with A and O cells but with B cells...
December 10, 2016: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
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