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Salima Qudsi-Sinclair, Enrique Borrás-Rubio, Juan F Abellan-Guillén, María Luz Padilla Del Rey, Guadalupe Ruiz-Merino
BACKGROUND: Knee osteoarthritis is a disease that affects a third of the population over 65 years of age, and it is increasingly becoming a motive for consultation and a source of pain and disability. The gold standard surgical treatment is a total knee arthroplasty; however, 15% to 30% of patients who have undergone surgery continue to experience pain and functional limitation. METHODS: A double-blind, randomized clinical study compared neurolysis using traditional radiofrequency (RF) to local anesthetic and corticosteroid block of the superolateral, superomedial, and inferomedial branches of the knee genicular nerves in patients who had total knee arthroplasty but still experience pain...
September 19, 2016: Pain Practice: the Official Journal of World Institute of Pain
Brian J Yun, M G Myriam Hunink, Anand M Prabhakar, Marilyn Heng, Shan W Liu, Rameez Qudsi, Ali S Raja
STUDY OBJECTIVE: Hip fractures cause significant morbidity and mortality. Determining the optimal diagnostic strategy for the subset of patients with potential occult hip fracture remains challenging. We determined the most cost-effective strategy for the diagnosis of occult hip fractures from the choices of performing only computed topography (CT), performing only magnetic resonance imaging (MRI), performing CT and if negative performing MRI (MRI selective strategy), or discharging the patient without advanced imaging...
June 10, 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
Suzan Alharbi, Mona Elsafadi, Mohammed Mobarak, Ali Alrwili, Radhakrishnan Vishnubalaji, Muthurangan Manikandan, Fatma Al-Qudsi, Saleh Karim, May Al-Nabaheen, Abdullah Aldahmash, Amer Mahmood
The fine structures of mouse embryonic stem cells (mESCs) grown as colonies and differentiated in three-dimensional (3D) culture as embryoid bodies (EBs) were analyzed by transmission electron microscopy. Undifferentiated mESCs expressed markers that proved their pluripotency. Differentiated EBs expressed different differentiation marker proteins from the three germ layers. The ultrastructure of mESCs revealed the presence of microvilli on the cell surfaces, large and deep infolded nuclei, low cytoplasm-to-nuclear ratios, frequent lipid droplets, nonprominent Golgi apparatus, and smooth endoplasmic reticulum...
April 2014: Cellular Reprogramming
Ahmed H Mitwalli, Jamal S Al Wakeel, Sameer Hurraib, Abu Aisha, Abdulkaraem Al Suwaida, Awatif Alam, Durdana Hammad, Fathia Sulimani, Nawaz A Memon, Akram Askar, Ali Al Tuwaijri, Abdo Qudsi
To evaluate the outcome of low doses of cyclophosphamide (Cyclo) therapy in lupus nephritis (LN) patients, we studied 117 biopsy-proven, de novo LN WHO class IV patients double-blinded and randomized in December 1997 to receive Cyclo in different doses; Group I (n=73) received Cyclo 10 mg/kg monthly for six months then every two months for 12 months. Group II (n=44) received Cyclo 5 mg/kg monthly for six months then every two months for 36 months. The patients were followed-up till January 2007. Six months post-induction values for creatinine clearance were significantly higher in Group I (67...
September 2011: Saudi Journal of Kidney Diseases and Transplantation
Jamal Al-wakeel, Mohammad Al-Ghonaim, Abdulkareem Al-Suwaida, Akram Askar, Saira Usama, Niaz Feraz, Iqbal Hamid Shah, Nawaz Memon, Abdo Qudsi, Fathia Sulaimani
Peritoneal dialysis (PD) is a well-established modality for treatment of patients with end-stage renal disease, giving excellent patient and technique survival rates. In Saudi Arabia, data collected by the Saudi Center for Organ Transplantation showed that in 2008, patients on PD accounted for a mere 4.8% of total patients on renal replacement therapy, including hemodialysis and renal transplantation. This study was conducted to identify the characteristics of membrane permeability in the Saudi population and to assess the role of various factors affecting solute transport across the peritoneal membrane...
January 2011: Saudi Journal of Kidney Diseases and Transplantation
Carl R Walkley, Rameez Qudsi, Vijay G Sankaran, Jennifer A Perry, Monica Gostissa, Sanford I Roth, Stephen J Rodda, Erin Snay, Patricia Dunning, Frederic H Fahey, Frederick W Alt, Andrew P McMahon, Stuart H Orkin
Osteosarcoma is the most common primary malignant tumor of bone. Analysis of familial cancer syndromes and sporadic cases has strongly implicated both p53 and pRb in its pathogenesis; however, the relative contribution of these mutations to the initiation of osteosarcoma is unclear. We describe here the generation and characterization of a genetically engineered mouse model in which all animals develop short latency malignant osteosarcoma. The genetically engineered mouse model is based on osteoblast-restricted deletion of p53 and pRb...
June 15, 2008: Genes & Development
Jamal S Al Wakeel, Ahmed H Mitwalli, Nauman Tarif, Durdana Hammad, Hassan Abu-Aisha, Nawaz Memon, Awatif Alam, Fathia Suliman, Akram Askar, Abdo Qudsi
To evaluate the complications of CAPD and their contributing factors in order to improve the patients' survival and reduce morbidity and mortality, we studied records of 65 CAPD patients treated at our hospital from October 1996 to January 2002. There were 32 (49%) males and the mean age of the patients was 48 +/- 16 years. All the patients were on the twin bag CAPD system. The mean duration of follow-up on CAPD was 29 +/- 20 months. There were 75 episodes of complications occurring in the patients with a rate of 0...
January 2005: Saudi Journal of Kidney Diseases and Transplantation
Nauman Tarif, Ahmed Hasan Mitwalli, Jamal Saleh Al-Wakeel, Pravin Chandra Patel, Saleh Ali Al-Smayer, Hani Kamal Najm, Abdoo Qudsi, Hassan Abu-Aisha
Aortic dissection may be associated with renal disease. The presentation, especially in the later stages of the process, includes proteinuria, hematuria and impairment of renal function. Thus the clinical picture may be confused with glomerulonephritis or hypertension. We present a case of ischemic nephropathy resulting from involvement of the right kidney by an aortic dissection. The pateint presented with the nephrotic syndrome some two and a half months after the probable time when the aortic disection had occurred...
April 2002: Saudi Journal of Kidney Diseases and Transplantation
Jamal S Al Wakeel, Ahmed H Mitwalli, Nauman Tarif, Awatif A Alam, Durdana Hammad, Hassan Abu-Aisha, Nawaz Memon, Fathia Sulimani, Akram Askar, Abdo Qudsi
Glomerulonephritis (GN) is a major cause of chronic renal failure (CRF). To evaluate the trends and outcome with modern improved treatment strategies, we retrospectively reviewed the clinical records of 120 patients with biopsy proven primary GN at our center from January 1990 to June 2001. All the biopsy specimens were subjected to light, electron and immunofluorescent microscopy. The recorded clinical parameters included the presenting symptoms, blood pressure readings, complete blood count, urinalysis, 24-hr urinary protein excretion, creatinine clearance besides rendered therapy and the outcome...
October 2004: Saudi Journal of Kidney Diseases and Transplantation
Christian Weinand, Rajiv Gupta, Albert Y Huang, Eli Weinberg, Ijad Madisch, Rameez A Qudsi, Craig M Neville, Irina Pomerantseva, Joseph P Vacanti
Availability of grafts and morbidity at the donor site limit autologous transplantation in patients requiring bone reconstruction. A tissue-engineering approach can overcome these limitations by producing bone-like tissue of custom shape and size from isolated cells. Several hydrogels facilitate osteogenesis on porous scaffolds; however, the relative suitability of various hydrogels has not been rigorously assessed. Fibrin glue, alginate, and collagen I hydrogels were mixed with swine bone marrow-derived differentiated mesenchymal stem cells (MSCs), applied to 3-dimensionally printed porous beta-tricalcium phosphate (beta-TCP) scaffolds and implanted subcutaneously in nude mice...
April 2007: Tissue Engineering
S S Al-qudsi
Relying on demographic and labor surveys which the Palestinian Central Bureau of Statistics collected in 1995, this article investigates the profile of West Bank and Gaza refugees. Refugees are better educated and have higher fertility than non-refugee Palestinians, but the difference is small. However, they have a significantly lower participation rate, a higher unemployment rate and a higher incidence of arrests and work stoppage than the corresponding rates among non-refugee Palestinians. A smaller proportion of Palestinians commute to work into the Israeli labor market and refugees earn lower wages than nonrefugees...
2000: International Migration
S S Al-qudsi, N M Shah
"A human capital framework is utilized to examine the economic progress of nine nationality groups of foreign workers [in Kuwait] using data from the 1983 national Labor Survey. The sources of earnings' variations of particular interest to us included different degrees of education and experience transferability, occupational affiliation and ethnic background. In general, the results derived from the analysis suggest that 1) foreign workers achieve a discernible economic progress as their residence lengthens; 2) the rate of economic progress varies depending on worker's education, home and Kuwait-specific experience, occupational status and ethnic background; and 3) about one third of the earnings inequality is due to unexplained factors including discrimination...
1991: International Migration Review
S Al-qudsi
No abstract text is available yet for this article.
1998: Journal of Population Economics
N M Shah, S S Al-qudsi, M A Shah
The author examines trends in the roles of immigrant Asian women workers in Kuwait, using data from published censuses and reports and from three national-level surveys conducted in 1977-1979, 1983, and 1986-1987. "The study deals separately with the two major types of migrants: the domestic servants and the clerical and professional (or semiprofessional) workers.... The policies of sending countries and of Kuwait are discussed to reach some conclusions about the likely future patterns of migration of Asian women workers to Kuwait...
1991: International Migration Review
F S Qudsi
No abstract text is available yet for this article.
January 1967: Majallat Tibb Al-asnān Al-Sūrīyah
F S Al-Qudsi
No abstract text is available yet for this article.
September 1972: Iraqi Dental Journal
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