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https://www.readbyqxmd.com/read/29454252/human-papillomavirus-detection-using-pcr-and-atr-ftir-for-cervical-cancer-screening
#1
Taciana Rymsza, Eliane Aline Ribeiro, Luis Felipe das Chagas E Silva de Carvalho, Tanmoy Bhattacharjee, Renata de Azevedo Canevari
The human papillomavirus (HPV) genital infection is considered one of the most common sexually transmitted diseases worldwide, and has been associated with cervical cancer. The objective of this study was to investigate the efficacy of the diagnostic methods: polymerase chain reaction (PCR) and Fourier transform infrared (FTIR) equipped with an ATR (Attenuated Total Reflectance) unit (Pike Tech) spectroscopy, to diagnose HPV infection in women undergoing gynecological examination. Seventeen patients (41.46%) of the 41 patients analyzed were diagnosed with exophytic/condyloma acuminate lesions by clinical analysis, 29 patients (70...
February 5, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29454196/sexually-transmitted-infections-and-immune-activation-among-hiv-infected-but-virally-suppressed-youth-on-antiretroviral-therapy
#2
Tanya L Kowalczyk Mullins, Su X Li, James Bethel, Maureen M Goodenow, Stephanie Hudey, John W Sleasman
BACKGROUND: Human immunodeficiency virus (HIV) infection is associated with chronic immune activation, and concurrent sexually transmitted infections (STIs) may increase immune activation. OBJECTIVES: Because HIV-infected youth are at high risk of STIs and little is known about the impact of STIs on immune activation in HIV-infected youth, we conducted an exploratory study examining the association between STIs and systemic inflammation and immune activation among HIV-infected adolescents...
February 7, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29452936/use-of-telemedicine-in-the-management-of-infectious-diseases
#3
G Gras
Communication technologies have invaded our daily lives. Several studies have assessed these technologies in the management of infectious diseases (mainly HIV). Weekly short text messages and real-time compliance monitoring assessed in HIV patients are both associated with higher compliance in low-income countries. Virtual consultations to monitor stable chronic HIV patients or tuberculosis treatment in high-income countries appear to be acceptable and efficient. Although assessed in small studies, virtual monitoring seems to reinforce the doctor-patient relationship and the relation between primary care settings and hospitals in various infectious diseases (endocarditis, urinary tract infection, skin and soft tissue infection, HIV, tuberculosis, hepatitis C)...
February 13, 2018: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/29452257/microbiota-changes-impact-on-sexually-transmitted-infections-and-the-development-of-pelvic-inflammatory-disease
#4
Nathalie Loeper, Simon Graspeuntner, Jan Rupp
The integrity of the human urogenital microbiome is crucial for women's health and well-being. An imbalance of the urogenital microbiota increases the risk for sexually transmitted infections. In this review, we discuss the microbiota composition of the female urogenital tract and its role in protecting from sexually transmitted infections and the emergence of pelvic inflammatory disease.
February 13, 2018: Microbes and Infection
https://www.readbyqxmd.com/read/29451611/factors-associated-with-hiv-co-infection-in-cases-of-acquired-syphilis-reported-in-a-reference-center-for-sexually-transmitted-diseases-and-aids-in-the-municipality-of-s%C3%A3-o-paulo-brazil-2014
#5
Carla Gianna Luppi, Solange Eduardo Chabu Gomes, Roberto José Carvalho da Silva, Amanda Miyako Ueno, Anna Maria Kamimura Dos Santos, Ângela Tayra, Renata Ferreira Takahashi
OBJECTIVE: to describe sociodemographic and behavioral characteristics and to identify factors associated with human immunodeficiency virus (HIV) co-infection in cases of acquired syphilis reported in a Reference Center for Sexually Transmitted Diseases (STD) and AIDS. METHODS: cross-sectional study with secondary data from a Reference Center for STD and AIDS in the municipality of São Paulo, Brazil, in 2014; the Poisson regression was used to estimate prevalence ratios (PR) and 95% confidence intervals (95%CI)...
2018: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/29450767/epididymo-orchitis-caused-by-enteric-organisms-in-men-35-years-old-beyond-fluoroquinolones
#6
REVIEW
Laura Ryan, Padraig Daly, Ivor Cullen, Maeve Doyle
Epididymo-orchitis is a common urological condition in men of all ages, causing a unilateral or bilateral swelling of the epididymis and/or testis. It is frequently caused by sexually transmitted infections, Chlamydia trachomatis and Neisseria gonorrheae, as well as common enteric organisms implicated in urinary tract infections. Men over 35 years old may develop epididymo-orchitis associated with enteric organisms, often associated with functional bladder outlet problems such as benign prostatic hyperplasia or urethral stricture disease...
February 15, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29447264/ebselen-alleviates-testicular-pathology-in-mice-with-zika-virus-infection-and-prevents-its-sexual-transmission
#7
Yogy Simanjuntak, Jian-Jong Liang, Si-Yu Chen, Jin-Kun Li, Yi-Ling Lee, Han-Chung Wu, Yi-Ling Lin
Despite the low case fatality, Zika virus (ZIKV) infection has been associated with microcephaly in infants and Guillain-Barré syndrome. Antiviral and vaccine developments against ZIKV are still ongoing; therefore, in the meantime, preventing the disease transmission is critical. Primarily transmitted by Aedes species mosquitoes, ZIKV also can be sexually transmitted. We used AG129 mice lacking interferon-α/β and -γ receptors to study the testicular pathogenesis and sexual transmission of ZIKV. Infection of ZIKV progressively damaged mouse testes, increased testicular oxidative stress as indicated by the levels of reactive oxygen species, nitric oxide, glutathione peroxidase 4, spermatogenesis-associated-18 homolog in sperm and pro-inflammatory cytokines including IL-1β, IL-6, and G-CSF...
February 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29446470/hev-and-hav-seroprevalence-in-men-that-have-sex-with-men-msm-an-update-from-milan-italy
#8
Letizia Greco, Sara Colonia Uceda Renteria, Davide Guarneri, Anna Orlandi, Antonella Zoccoli, Susanna Benardon, Marco Cusini, Giovanna Lunghi
Hepatitis E virus (HEV) is a feco-orally transmitted pathogen and one of the most common cause of acute hepatitis worldwide. Recent studies in developed countries suggested that a direct human-to-human contact such as for sexually transmitted diseases may play a significant role in the HEV spread. The aim of this study was to investigate the seroprevalence of HEV and HAV in a group of MSM, including subjects HIV and Treponema infected, in Milan, Italy. The overall anti HEV IgG seroprevalence in MSM was 10.2% (65/636), instead in the control group the detection rate was 5...
February 15, 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/29444689/comprehensive-knowledge-on-cervical-cancer-attitude-towards-its-screening-and-associated-factors-among-women-aged-30-49-years-in-finote-selam-town-northwest-ethiopia
#9
Alehegn Bishaw Geremew, Abebaw Addis Gelagay, Telake Azale
BACKGROUND: Screening services for cervical pre-cancerous lesions is currently available for all women aged 30-49 years at public hospitals in Ethiopia. Though women's knowledge and their attitude are determinants for the uptake the screening service, there is limited information on these regards. Therefore, this study aimed to assess comprehensive knowledge on cervical cancer, attitudes towards the screening, and associated factors among women aged 30-49 years at Finote Selam town, northwest Ethiopia...
February 14, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29444462/photodynamic-therapy-as-a-new-approach-to-trichomonas-vaginalis-inactivation
#10
Thaisa Helena Silva Fonseca, Marina Alacoque, Fabrício Marcus Silva Oliveira, Betânia Maria Soares, Henrique Vitor Leite, Marcelo Vidigal Caliari, Maria Aparecida Gomes, Haendel Busatti
The emergence of nitroimidazole resistant isolates has been an aggravating factor in the treatment of trichomoniasis, the most common non-viral sexually transmitted disease in the world. This particularity highlights the importance of new technologies that are safe, effective, and have minor side effects or resistance. Hence, we evaluated the effectiveness of photodynamic therapy on the inactivation of Trichomonas vaginalis in vitro. We used methylene blue as a photosensitizing substance, and a light-emitting diode (LED) for irradiation of metronidazole sensitive and resistant strains...
February 11, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29440938/domestic-violence-a-hidden-barrier-to-contraceptive-use-among-women-in-nigeria
#11
Ghose Bishwajit, Sanni Yaya
Background: The nonuse of family planning methods remains a major public health concern in the low-and-middle-income countries, especially due to its impact on unwanted pregnancy, high rate of abortion, and transmission of sexually transmitted diseases. Various demographic and socioeconomic factors have been reported to be associated with the nonuse of family planning methods. In the present study, we aimed at assessing the influence of domestic violence (DV) on contraceptive use among ever married women in Nigeria...
2018: Open access journal of contraception
https://www.readbyqxmd.com/read/29439321/knowledge-attitude-and-practice-of-hiv-aids-among-workers-at-china-first-highway-engineering-company-at-bilibila-sokota-road-project-sokota-ethiopia
#12
Mebratu Tarekegne, Addis Adera, Kalab Haile, Derara Guyo
OBJECTIVE: The aim of this study was to assess Bilbila Sokota Road Project workers' knowledge, attitude and practice on HIV/AIDS in China first highway engineering Company. METHODS: A cross sectional Survey was conducted among workers in China first high way engineering Company at Bilbila Sokota road project, Sokota, Ethiopia. Fifty-five workers were taken from project site/company. Data was collected using a validated self-administrated standardized questionnaire on Knowledge, attitude and practice including behavioral change regarding HIV/AIDS...
February 5, 2018: Human Antibodies
https://www.readbyqxmd.com/read/29434478/neisseria-gonorrhoeae-induced-inflammatory-pyroptosis-in-human-macrophages-is-dependent-on-intracellular-gonococci-and-lipooligosaccharide
#13
Jessica Leigh Ritter, Caroline Attardo Genco
Neisseria gonorrhoeae, the human obligate pathogen responsible for the sexually transmitted disease gonorrhea, has evolved several mechanisms to evade the host immune response. One such mechanism is the modulation of host cell death pathways. In this study, we defined cell death pathways induced by N gonorrhoeae in human monocyte-derived macrophages (MDMs). In a dose-dependent manner, N gonorrhoeae stimulation of MDMs resulted in caspase 1 and 4-dependent cell deaths, indicative of canonical and noncanonical pyroptosis, respectively...
2018: Journal of Cell Death
https://www.readbyqxmd.com/read/29434477/high-burden-of-human-papillomavirus-infection-in-madagascar-comparison-with-other-sexually-transmitted-infections
#14
Jérôme Bigoni, Rosa Catarino, Caroline Benski, Manuela Viviano, Maria Munoz, Honoré Tilahizandry, Patrick Petignat, Pierre Vassilakos
Background: In Madagascar, human papillomavirus (HPV), human immunodeficiency virus (HIV), and hepatitis B virus (HBV) infection, as well as syphilis share common risk factors but seem to differ in their prevalence. We measured and compared their prevalence in the country. Methods: The data used in this study came from the Saint Damien Health Centre in Ambanja, Madagascar. The tests used for disease detection were the Alere Determine, Virucheck, rapid plasma reagin, and S-DRY self-HPV samples for HIV infection, HBV infection, syphilis, and HPV infection, respectively...
2018: Infectious Diseases
https://www.readbyqxmd.com/read/29433695/zika-en-p%C3%A3-diatrie-que-retenir
#15
P Minodier
Zikavirus (ZV) is a flavivirus transmitted by Aedes mosquitoes' bites. Sexual transmission is possible. Common ZV infection is asymptomatic or associates flu-like signs. Guillain-Barre syndrome following ZV infection is rare. Foetal infection, during the first trimester of pregnancy especially, can lead to severe neurological troubles. Diagnosis relies on blood and urine RT-PCR during the acute phase, and serology later in the disease. ELISA assays false positives are reported among patients infected with another flavivirus, whereas sero-neutralization is more specific...
December 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29433363/to-douche-or-not-to-douche-hygiene-habits-may-have-detrimental-effects-on-vaginal-microbiota
#16
Erdogan Aslan, Nadia Bechelaghem
The importance of a healthy vaginal micro-flora is indisputable. Therefore, intravaginal practices, such as vaginal douching (VD), may inhibit or lower the colonisation of beneficial Lactobacilli strains. Although the results of disrupted vaginal microbiota have been widely reported in the literature, direct microbicidal effects of products used for VD have been rarely studied. Moreover, there are certain studies advocating the beneficial effects of VD. This in vitro study was designed to provide more evidence to help health care givers in disseminating the knowledge that VD might have detrimental effects on vaginal microbiota...
February 13, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29429421/epidemiology-and-risk-factors-for-hepatitis-c-virus-infection-in-a-high-prevalence-population
#17
M A Fill, L A Sizemore, M Rickles, K C Cooper, C M Buecker, H L Mullins, M G Hofmeister, W E Abara, M A Foster, A K Asher, W Schaffner, J R Dunn, T F Jones, C Wester
To understand increasing rates of hepatitis C virus (HCV) infection in Tennessee, we conducted testing, risk factor analysis and a nested case-control study among persons who use drugs. During June-October 2016, HCV testing with risk factor assessment was conducted in sexually transmitted disease clinics, family planning clinics and an addiction treatment facility in eastern Tennessee; data were analysed by using multivariable logistic regression. A nested case-control study was conducted to assess drug-using risks and behaviours among persons who reported intranasal or injection drug use (IDU)...
February 12, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29427299/herpes-simplex-virus-type-2-igg-antibodies-in-sera-of-umbilical-cord-as-a-proxy-for-placental-infection-in-asymptomatic-pregnant-women
#18
Fabiana Finger-Jardim, Emiliana Claro Avila, Vanusa Pousada da Hora, Paula Costa Dos Santos, Carla Vitola Gonçalves, Gil Mor, Ana Maria Barral de Martinez, Marcelo Alves Soares
PROBLEM: Herpes simplex virus type 2 (HSV-2) infection is one of the most prevalent diseases worldwide and is mainly sexually transmitted. When infecting pregnant women, HSV-2 is able to infect the placenta, can reach the fetus, and may affect the fetal development. We sought to determine the prevalence of HSV-2 infection and reactivation in asymptomatic pregnant women, the correlation between IgG in the maternal circulation and cord blood, and the correlation between circulating IgG, placental, and newborn infection (blood cord)...
February 10, 2018: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29427023/-anogenital-warts-and-hpv-associated-precancers-looking-into-the-recently-passed-german-s2k-guideline
#19
REVIEW
P Schneede, B Schlenker
Anogenital warts are the most frequently sexually transmitted disease caused by viral infections worldwide. People's lifetime risk to suffer from this disease or HPV-associated precancers counts to more than 10%. The therapy and the recurrence rates of both disorders continue to be challenging in Germany because the coverage rate of the preventive HPV vaccination is still insufficient. This underlines the importance of a recently passed interdisciplinary German guideline on anogenital HPV lesions. This article summarizes the main aspects of the new guideline...
February 9, 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29425793/risky-sexual-behavior-among-cannabis-users-the-role-of-protective-behavioral-strategies
#20
Julia D Buckner, Elizabeth M Lewis, Sonia M Shah, Katherine A Walukevich
Cannabis users tend to use condoms less often than cannabis abstainers, placing them at risk for sexually transmitted disease and unplanned pregnancies. This is especially problematic among college students, who experience such problems at especially high rates. Despite accumulating data indicating that cannabis users are less likely to use condoms, little research has identified potentially malleable cognitive vulnerability factors that may be related to condom use in this vulnerable population. Thus, the current study tested whether cannabis users believed others use condoms less often and/or whether they engaged in less condom-related protective behavior strategies (PBS) than cannabis abstainers and whether cannabis use status was indirectly related to condom use via these vulnerability factors...
February 1, 2018: Addictive Behaviors
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