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Sexually transmitted diseases

Teris Cheung, Joseph T F Lau, Johnson Z Wang, P K H Mo, Y S Ho
OBJECTIVES: The highly infectious human papillomavirus (HPV) causes both genital warts and cervical cancer in women. In 2009, the prevalence of genital warts in Hong Kong was 203.7 per 100,000 person-years. Cervical cancer, more seriously, was the eight most common cancer among women and girls in Hong Kong, accounting for 2.3% of all new cancer cases in females in 2014. Cervical cancer is a significant global public health problem and HPV is a major risk factor leading to the development of cervical cancer...
2018: PloS One
Jace D Pierce, Kelly R Ylitalo, Beth A Lanning, Christine C Limbers
BACKGROUND: Young men who have sex with men (YMSM) are disproportionally affected by HIV and exhibit low levels of HIV testing. The purpose of this study was to examine the relationship between sex education and subsequent HIV testing among YMSM. METHODS: Data from sexually active men aged 15-24 years at interview in the 2006-2010 or 2011-2015 National Survey of Family Growth. Sex education included three contexts (formal institutions [e.g., schools], parents, and healthcare providers) and specific topics...
June 12, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Laura Kann, Tim McManus, William A Harris, Shari L Shanklin, Katherine H Flint, Barbara Queen, Richard Lowry, David Chyen, Lisa Whittle, Jemekia Thornton, Connie Lim, Denise Bradford, Yoshimi Yamakawa, Michelle Leon, Nancy Brener, Kathleen A Ethier
PROBLEM: Health-risk behaviors contribute to the leading causes of morbidity and mortality among youth and adults in the United States. In addition, significant health disparities exist among demographic subgroups of youth defined by sex, race/ethnicity, and grade in school and between sexual minority and nonsexual minority youth. Population-based data on the most important health-related behaviors at the national, state, and local levels can be used to help monitor the effectiveness of public health interventions designed to protect and promote the health of youth at the national, state, and local levels...
June 15, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
Jata S Misra, Anand N Srivastava, Hem P Gupta
OBJECTIVE: Cytological screening was carried out in rural women of Lucknow West, India, through a camp approach to detect cervical cancer in its preinvasive phase and to see whether the primitive living conditions in the villages have any effect on the incidence of precancer and carcinoma of the cervix and the associated predisposing factors of cervical carcinogenesis. STUDY DESIGN: During a span of 4 years (May 2013 to March 2017), a total of 135 camps were organized under the auspice of Era's Lucknow Medical College and Hospital (Lucknow, India)...
June 13, 2018: Acta Cytologica
Luis Alberto Mendez, Ricardo Martinez, Manolo Rubio
Oral lesions can have widely variable aetiology, hence, the importance of a comprehensive history and oral examination. We describe the case of a 47-year-old man who presented with an incidental erythematous lesion of the soft palate. The diagnosis was established during a routine dental examination. We found the lesion to be associated with the practice of fellatio. Oral sex is a very common sexual practice, and as clinicians we should consider it as a potential cause of palatal lesions in our differential diagnosis...
June 11, 2018: BMJ Case Reports
Agustin L Lujan, Diego O Croci, Julián A Gambarte Tudela, Antonella D Losinno, Alejandro J Cagnoni, Karina V Mariño, María T Damiani, Gabriel A Rabinovich
Chlamydia trachomatis ( Ct ) constitutes the most prevalent sexually transmitted bacterium worldwide. Chlamydial infections can lead to severe clinical sequelae including pelvic inflammatory disease, ectopic pregnancy, and tubal infertility. As an obligate intracellular pathogen, Ct has evolved multiple strategies to promote adhesion and invasion of host cells, including those involving both bacterial and host glycans. Here, we show that galectin-1 (Gal1), an endogenous lectin widely expressed in female and male genital tracts, promotes Ct infection...
June 11, 2018: Proceedings of the National Academy of Sciences of the United States of America
Peter H Kilmarx, Elizabeth Gonese, David A Lewis, Z Mike Chirenje, Beth A Tippett Barr, Ahmed S Latif, Lovemore Gwanzura, H Hunter Handsfield, Anna Machiha, Owen Mugurungi, Cornelius A Rietmeijer
BACKGROUND: HIV and other sexually transmitted infections (STI) frequently co-occur. We conducted HIV diagnostic testing in an assessment of the etiologies of major STI syndromes in Zimbabwe. METHODS: A total of 600 patients were enrolled at six geographically diverse, high-volume STI clinics in Zimbabwe in 2014-15: 200 men with urethral discharge, 200 women with vaginal discharge, and 100 men and 100 women each with genital ulcer disease (GUD). Patients completed a questionnaire, underwent a genital examination, and had specimens taken for etiologic testing...
2018: PloS One
John Schneider, L Philip Schumm, Maya Fraser, Vijay Yeldandi, Chuanhong Liao
Contact tracing for venereal disease control has been widespread since 1936 and relies on reported information about contacts' attributes to determine whether two contacts may represent the same individual. We developed and implemented a gold-standard for determining overlap between contacts reported by different individuals using cell phone numbers as unique identifiers. This method was then used to evaluate the performance of using reported names and demographic characteristics to infer overlap. Cell-phone numbers, names and demographic data for a sample of high-risk men in India and their contacts were collected using a novel, hybrid instrument involving both cell-phone data extraction and Computer-Assisted Personal Interviewing (CAPI)...
June 8, 2018: Scientific Reports
Cydnee Ng, Rana Najjar, Natalie DiPietro Mager, Sally Rafie
OBJECTIVES: The primary objective was to assess pharmacist and student pharmacist current involvement and interest in providing preconception care services. Secondary objectives were to assess comfort in providing these services to various subpopulations in addition to training and resource needs. METHODS: A cross-sectional online survey was conducted in the United States and its territories from August 26 to October 14, 2016. Pharmacists and student pharmacists were recruited via a Facebook advertisement to participate in a self-administered survey assessing experiences, interest, and comfort in providing preconception care services in addition to training and resource needs...
June 5, 2018: Journal of the American Pharmacists Association: JAPhA
Khosheh Khaleghinezhad, Nourossadat Kariman, Fatemeh Nahidi, Abbas Ebadi, Malihe Nasiri
Background: Reproductive health is one of the most important aspects of life. Moreover, rural women constitute the largest demographic in society who are deprived of health services. Objective: To determine the reproductive health needs of rural women of reproductive age. Methods: This cross-sectional study was conducted on 405 rural women referring to the rural healthcare centers of Neyshabur, Iran, in 2017. The study population was selected through random multistage sampling technique...
April 2018: Electronic Physician
Nigusie Fetene, Wubegzier Mekonnen
BACKGROUND: Risky sexual behaviors adversely affect the health of youth and young adults exposing them to sexually transmitted infections including HIV/AIDS and unwanted pregnancy to females that in turn lead to deleterious health, social and economic consequences. Youth centers inform their clients on sexually transmitted diseases, including HIV/AIDS, unwanted pregnancy, high risk abortion, and other reproductive health problems. Therefore, this study was designed to assess the prevalence of risky sexual behaviors among youth center reproductive health clinic users and non-users in Addis Ababa...
2018: PloS One
Mohamed El Amraoui, Naoufal Hjira
Salmonelloses are bacterial infections of the faecal peril; they are endemic in some regions of the world. They can colonize almost any organ hematogenously, hence, severe forms may be observed. We report a case of typhoid fever in a 16-year old young adolescent with no medical history, sexually transmitted diseases or sexual intercourses, presenting with necrotic scrotal ulcerations evolving over the past 3 weeks in a context of fever, diarrhoea, weight loss and alteration of the general state. Paraclinical assessment showed 7g/dl hypochromic microcyticanemia with target cells in blood smear and normal hemoglobin electrophoresis, biologic inflammatory syndrome, malabsorption syndrome, cytolysis and hepatic cholestasis 20 times above the normal, hepatosplenomegaly, normal viral serologic testing (HBV, HCV, HIV, EBV and CMV) and positive testing for salmonella...
2018: Pan African Medical Journal
Annika Röcker, Nadia R Roan, Jay Kant Yadav, Marcus Fändrich, Jan Münch
Amyloid fibrils are linear polypeptide aggregates with a cross-β structure. These fibrils are best known for their association with neurodegenerative diseases, such as Alzheimer's or Parkinson's, but they may also be used by living organisms as functional units, e.g. in the synthesis of melanin or in the formation of bacterial biofilms. About a decade ago, in a search for semen factors that modulate infection by HIV-1 (a sexually transmitted virus and the causative agent of the acquired immune deficiency syndrome (AIDS)), it was demonstrated that semen harbors amyloid fibrils capable of markedly increasing HIV infection rates...
June 6, 2018: Chemical Communications: Chem Comm
Christian T Bautista, Bruce P Hollingsworth, Jose L Sanchez
BACKGROUND: In the U.S. military, chlamydia is the mostly commonly diagnosed bacterial sexually transmitted infection and the rates of pelvic inflammatory disease (PID) have remained high since the early 2000s. METHODS: The relationship between the number of chlamydia diagnoses and risk of PID was investigated in a retrospective cohort analysis, among chlamydia cases in the U.S. Army during 2006-2012. Cox regression model was used to estimate hazard ratios (HR) for associations between the number of repeat chlamydia diagnoses and PID...
June 4, 2018: Sexually Transmitted Diseases
Jocelyn Ronda, Charlotte A Gaydos, Jamie Perin, Lisa Tabacco, Jenell Coleman, Maria Trent
BACKGROUND: Mycoplasma genitalium (MG) is a common sexually transmitted infection (STI) but there are limited strategies to identify individuals at risk of MG. Previously a sex risk quiz was used to predict STIs including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (GC), and/or Trichomonas vaginalis (TV). The original quiz categorized individuals ≤25 years old as at risk of STIs, but the Centers for Disease Control identifies females <25 years old as at risk of STIs. In this study, the quiz was changed to categorize females <25 years old as high risk...
June 4, 2018: Sexually Transmitted Diseases
Upuli Amaranganie Pushpakumari Perera, Chrishantha Abeysena
BACKGROUND: Risky sexual behaviors (RSB) are becoming an important problem all over the world. RSB are defined as behaviors leading to sexually transmitted diseases and unintended pregnancies. The objective of this study was to determine the prevalence and associated factors of RSB among undergraduate students in state universities of Western Province in Sri Lanka. METHODS: A descriptive cross sectional study was conducted on1575 second and third year undergraduates using stratified cluster sampling of the selected universities...
June 4, 2018: Reproductive Health
Sean D Young, Elizabeth A Torrone, John Urata, Sevgi O Aral
BACKGROUND: Researchers have suggested that social media and online search data might be used to monitor and predict syphilis and other sexually transmitted diseases. Because people at risk for syphilis might seek sexual health and risk-related information on the internet, we investigated associations between internet state-level search query data (e.g., Google Trends) and reported weekly syphilis cases. METHODS: We obtained weekly counts of reported primary and secondary syphilis for 50 states from 2012 to 2014 from the US Centers for Disease Control and Prevention...
July 2018: Epidemiology
Behzad Damari, Siamak Alikhani, Forouzan Akrami
Background: Protecting the youth and adolescents' health is considered to be an indicator of health equity. The current study was conducted to analyze health status of the Iranian youth and adolescents, identify service gaps, and design action-oriented interventions. Methods: In this study with multimethods design conducted in 2014, first to identify and analyze the current situation, related articles and national and international documents were searched and reviewed...
2018: International Journal of Preventive Medicine
Phunlerd Piyaraj, Frits van Griensven, Timothy H Holtz, Philip A Mock, Anchalee Varangrat, Wipas Wimonsate, Warunee Thienkrua, Jaray Tongtoyai, Atitaya McNamara, Wannee Chonwattana, Kenrad E Nelson
BACKGROUND: The finding of casual sex partners on the internet and methamphetamine use have been described as risk factors for HIV infection in men who have sex with men (MSM). However, the interplay between these factors has not been studied prospectively in one design. This study aims to determine the associations between finding casual sex partners on the internet and incident methamphetamine use and HIV infection. METHODS: In this observational cohort study of Thai MSM, we recruited Bangkok residents aged 18 years or older with a history of penetrative male-to-male sex in the past 6 months...
May 31, 2018: Lancet HIV
Nunzia Zanotta, Giuseppina Campisciano, Federica Scrimin, Ura Blendi, Annalisa Marcuzzi, Ezio Vincenti, Sergio Crovella, Manola Comar
OBJECTIVE: The vulvar pain syndrome (VPS) is a multifactorial disease severely influencing the lifestyle of affected women. Among possible etiological factors, local injury, peripheral and/or central sensitization of the nervous system, and a chronic inflammatory status have been positively associated with the development of VPS. The identification of a constitutive altered local inflammatory profile in VPS women may represent an important point in the characterization of patients' phenotype as a useful marker influencing the vulvar micro-environment...
May 24, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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