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https://www.readbyqxmd.com/read/28879572/diligustilide-releases-h2s-and-stabilizes-s-nitrosothiols-in-ethanol-induced-lesions-on-rat-gastric-mucosa
#1
Josué Arturo Velázquez-Moyado, José Luis Balderas-López, Elizabeth Arlen Pineda-Peña, Brenda Lorena Sánchez-Ortiz, José Carlos Tavares-Carvalho, Andrés Navarrete
(Z,Z')-Diligustilide (DLG) or levistolide A is a dimeric phthalide isolated from Ligusticum porteri (Osha), the roots of which are used in the traditional treatment of many diseases including gastric aches. However, its action has not been completely elucidated. We analyzed the contributions of hydrogen sulfide and S-nitrosothiols to the action of DLG. Animals were pretreated with freshly formed in vitro nitrosothiol using Na2S and sodium nitroprusside to elucidate participation in the action of DLG. We also evaluated the production of H2S in vivo and in real time on the stomach via a specific electrode introduced into the stomachs of anaesthetized animals pretreated with DLG...
September 6, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28865927/construction-accident-narrative-classification-an-evaluation-of-text-mining-techniques
#2
Yang Miang Goh, C U Ubeynarayana
Learning from past accidents is fundamental to accident prevention. Thus, accident and near miss reporting are encouraged by organizations and regulators. However, for organizations managing large safety databases, the time taken to accurately classify accident and near miss narratives will be very significant. This study aims to evaluate the utility of various text mining classification techniques in classifying 1000 publicly available construction accident narratives obtained from the US OSHA website. The study evaluated six machine learning algorithms, including support vector machine (SVM), linear regression (LR), random forest (RF), k-nearest neighbor (KNN), decision tree (DT) and Naive Bayes (NB), and found that SVM produced the best performance in classifying the test set of 251 cases...
August 31, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28859618/evaluation-of-noise-hazard-during-the-holmium-laser-enucleation-of-prostate
#3
Huan Xu, Yan-Bo Chen, Meng Gu, Qi Chen, Zhong Wang
BACKGROUND: To evaluate noise hazard during holmium laser enucleation of the prostate (HoLEP), we designed a study to detect such a risk in this procedure. METHODS: This study was conducted over a 12-month period on 223 patients with benign prostatic hyperplasia (BPH), 121 of whom underwent HoLEP while those remaining underwent transurethral resection of the prostate (TURP). A sound level meter was used to detect the exposure of surgeons to noise. The recordings used were in accordance with the standards set by the Occupational Safety and Health Administration (OSHA) and the United States E nvironmental Protection A gency ...
August 31, 2017: BMC Urology
https://www.readbyqxmd.com/read/28820861/association-of-poultry-processing-industry-exposures-with-reports-of-occupational-finger-amputations-results-of-an-analysis-of-osha-severe-injury-report-sir-data
#4
Remington L Nevin, Jon Bernt, Michael Hodgson
OBJECTIVE: This analysis was conducted to identify industry exposures strongly associated with reports of finger amputation. METHODS: Reports of severe occupational injuries in the Occupational Safety and Health Administration (OSHA) Severe Injury Report (SIR) database were analyzed in relation to U.S. Census Bureau industry employment data. Industries with significantly elevated reporting odds ratios (RORs) and relative reporting risks (RRRs) were identified. Multiple population association measures including population attributable fraction (PAF) were calculated by industry...
August 17, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28819083/the-forgotten-realm-of-the-new-and-emerging-psychosocial-risk-factors
#5
Francesco Chirico
In Europe, employers of all private and public enterprises have a legal obligation to protect their employers by all the different types of workplace hazards to the safety and health of workers. The most important methods developed for the work-related stress risk assessment are based on the Cox's research commissioned by European Agency for Safety and Health at Work (EU-OSHA) and are the Management Standard HSE for work-related stress in United Kingdom, the START method in Germany, the Screening, Observation, Analysis, Expertise (SOBANE) in Belgium, and the National Institute for Prevention and Safety at Work (INAIL-ISPESL) model in Italy, the latter based on the British Management Standard...
August 17, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/28817554/occupational-distribution-of-campylobacteriosis-and-salmonellosis-cases-maryland-ohio-and-virginia-2014
#6
Chia-Ping Su, Marie A de Perio, Kathleen Fagan, Meghan L Smith, Ellen Salehi, Seth Levine, Karen Gruszynski, Sara E Luckhaupt
Campylobacter and Salmonella are leading causes of bacterial gastroenteritis in the United States and are estimated to cause >1 million episodes of domestically acquired illness annually (1). Campylobacter and Salmonella are primarily transmitted through contaminated food, but animal-to-human and human-to-human transmission can also occur (2,3). Although occupationally acquired infections have been reported, occupational risk factors have rarely been studied. In 2015, the Occupational Safety and Health Administration (OSHA) identified 63 suspected or confirmed cases of Campylobacter infection over 3...
August 18, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28806863/influence-of-gender-working-field-and-psychosocial-factors-on-the-vulnerability-for-burnout-in-mental-hospital-staff-results-of-an-austrian-cross-sectional-study
#7
Petra Schadenhofer, Michael Kundi, Heidemarie Abrahamian, Harald Stummer, Alexandra Kautzky-Willer
INTRODUCTION: According to the European Agency for Safety and Health at Work (EU-OSHA), hospitals represent a work environment with high job strain. Prolonged perceived occupational stress may result in symptoms of burnout, such as emotional exhaustion (EE), depersonalisation (DP) and reduced personal accomplishment (PA). Understanding which factors may reduce vulnerability for burnout is an important requirement for well-targeted occupational stress prevention in mental hospital staff...
August 14, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28774617/monitoring-and-factors-affecting-levels-of-airborne-and-water-bromoform-in-chlorinated-seawater-swimming-pools
#8
Jean-Luc Boudenne, Julien Parinet, Carine Demelas, Tarek Manasfi, Bruno Coulomb
Water and air quality of eight seawater swimming pools using chlorine disinfection was measured during four sampling campaigns, spread on one full-year, and in four thalassotherapy centers located in Southeast of France. Concentrations of trihalomethanes (THMs) in air and in water as well as concentrations of parameters, including nonpurgeable organic carbon (NPOC), free residual chlorine (Clf), pH, Kjeldhal Nitrogen (KN), salinity, conductivity, bromide ions and, water and air temperature, were measured. Water and air samples were collected in triplicates morning - at the opening of the pools -, noon and night - at the closing of the pools -, in summer and winter...
August 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28763387/the-south-carolina-environmental-public-health-tracking-program-s-role-in-monitoring-and-reducing-occupational-exposure-to-lead-public-health-actions-in-collaboration-with-the-south-carolina-occupational-safety-and-health-administration
#9
Harley T Davis, Chelsea Lynes, H Reed Corley
Per South Carolina (SC) Law §44-29-10, all blood lead test records are reportable. The SC Environmental Public Health Tracking (SC EPHT) program is directly involved in blood lead surveillance in SC, as it maintains the blood lead record database. Although Adult Blood Lead Epidemiology and Surveillance funding from the Centers for Disease Control and Prevention was discontinued in 2013, SC EPHT has continued to monitor and record adult blood lead test records.In 2012, SC EPHT signed a memorandum of understanding with the SC Occupational Safety and Health Administration (SC OSHA)...
September 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28742992/utilizing-secondary-agricultural-education-programs-to-deliver-evidence-based-grain-safety-training-for-young-and-beginning-workers
#10
Yuan-Hsin Cheng, William E Field, Roger L Tormoehlen, Brian F French
Purdue University's Agricultural Safety and Health Program (PUASHP) has collaborated with secondary agricultural education programs, including FFA Chapters, for over 70 years to deliver and promote agricultural safety and health programming. With support from a U.S. Department of Labor Susan Harwood Program grant, PUASHP utilized a Developing a Curriculum (DACUM) process to develop, implement, and evaluate an evidence-based curriculum for use with young and beginning workers, ages 16-20, exposed to hazards associated with grain storage and handling...
2017: Journal of Agromedicine
https://www.readbyqxmd.com/read/28703044/implementation-of-a-safe-patient-handling-program-in-a-multihospital-health-system-from-inception-to-sustainability-successes-over-8-years-and-ongoing-challenges
#11
Christine Olinski, Christine E Norton
Musculoskeletal injuries, especially back injuries, are among the most frequent injuries sustained by direct caregivers who lift, transfer, and reposition patients. These injuries can be debilitating and, for some caregivers, career ending. In the first year following implementation of the safe patient handling program in a multihospital health care system, an 82% reduction in Occupational Health and Safety Administration (OSHA) recordable patient handling injuries was realized, a 94% decrease in days away from work, an 85% reduction in restricted duty days, and an 82% reduction in incurred workers' compensation costs...
July 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28700929/a-cardiomyopathy-mutation-in-the-myosin-essential-light-chain-alters-actomyosin-structure
#12
Piyali Guhathakurta, Ewa Prochniewicz, Osha Roopnarine, John A Rohde, David D Thomas
We have used site-directed time-resolved fluorescence resonance energy transfer to determine the effect of a pathological mutation in the human ventricular essential light chain (hVELC) of myosin, on the structural dynamics of the actin-myosin complex. The hVELC modulates the function of actomyosin, through the interaction of its N-terminal extension with actin and its C-terminal lobe with the myosin heavy chain. Several mutations in hVELC are associated with hypertrophic cardiomyopathy (HCM). Some biochemical effects of these mutations are known, but further insight is needed about their effects on the structural dynamics of functioning actomyosin...
July 11, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28693807/inter-annual-variation-in-the-density-of-anthropogenic-debris-in-the-tasman-sea
#13
Osha-Ann Rudduck, Jennifer L Lavers, Andrew M Fischer, Silke Stuckenbrock, Paul B Sharp, Richard B Banati
An increasing number of studies highlight the risk of plastic pollution in the marine environment. However, systematic longitudinal data on the distribution and abundance of plastic debris remain sparse. Here we present the results of a two-year study of plastic pollution within the Tasman Sea, contrasted with a further year of data from the same region, in order to document how the density of debris varies across years in this area. Surface net tows were collected between Hobart, Tasmania and Sydney, Australia during the spring of 2013 and 2014 and compared with a subset of data from autumn 2012 from the same region...
July 7, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28691728/intervention-to-diminish-dehydration-and-kidney-damage-among-sugarcane-workers
#14
David H Wegman, Jenny Apelqvist, Matteo Bottai, Ulf Ekström, Ramón García-Trabanino, Jason Glaser, Christer Hogstedt, Kristina Jakobsson, Emmanuel Jarquín, Rebekah A I Lucas, Ilana Weiss, Catharina Wesseling, Theo Bodin
Objective The aim of this study was to assess the potential to reduce kidney function damage during the implementation of a water, rest, shade (WRS) and efficiency intervention program among sugarcane workers. Methods A WRS intervention program adapted from the US Occupational Safety and Health Administration (OSHA) coupled with an efficiency program began two months into the 5-month harvest. One of the two groups of workers studied was provided with portable water reservoirs, mobile shaded tents, and scheduled rest periods...
July 7, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28650713/occupational-chemical-exposures-a-collaboration-between-the-georgia-poison-center-and-the-occupational-safety-and-health-administration
#15
Aaron W Tustin, Alison Jones, Gaylord P Lopez, Glenn R Ketcham, Michael J Hodgson
CONTEXT: In the United States, regional poison centers frequently receive calls about toxic workplace exposures. Most poison centers do not share call details routinely with governmental regulatory agencies. Worker health and safety could be enhanced if regulators such as the Occupational Safety and Health Administration (OSHA) had the ability to investigate these events and prevent similar incidents. With this goal in mind, the Georgia Poison Center (GPC) began referring occupational exposures to OSHA in July 2014...
June 26, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28645965/the-perspective-of-european-researchers-of-national-occupational-safety-and-health-institutes-for-contributing-to-a-european-research-agenda-a-modified-delphi-study
#16
Diana Gagliardi, Bruna M Rondinone, Marco Mirabile, Giuliana Buresti, Peter Ellwood, Michel Hery, Peter Paszkiewicz, Antonio Valenti, Sergio Iavicoli
OBJECTIVES: This study, developed within the frame of the Partnership for European Research on Occupational Safety and Health joint research activities and based on the frame designed by the 2013 European Agency for Safety and Health at Work (EU-OSHA) study, is the first example of using the points of view of European occupational safety and health (OSH) researchers.The objective is to identify priorities for OSH research that may contribute to the achievement of present and future sustainable growth objectives set by the European strategies...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28636451/assessing-hydrogen-peroxide-vapor-exposure-from-hospital-sterilizers
#17
Robert Cornelia, P Richard Warburton
This study examines the hydrogen peroxide concentrations measured near four models of hydrogen peroxide sterilizers, from two manufacturers, monitored in seven hospitals across the U.S. and Canada over several years. The results showed that the majority of sterilizers do not emit hazardous levels of hydrogen peroxide and none of them exceeded the OSHA PEL of 1 ppm (8-hr time-weighted average (TWA)), however several of the sterilizers exceeded 3 ppm, the short-term exposure limit in two states: Washington and Hawaii...
September 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28604767/correlation-between-airborne-manganese-concentration-at-the-workstations-in-the-iron-foundry-and-manganese-concentration-in-workers-blood
#18
Seyedtaghi Mirmohammadi, Yosef Moghaddasi, Jamshid Yazdani, Razyeh Yousefinejad, Yahya Esfandyari, Mohsen Gorgani, Manijeh Habibpour
BACKGROUND: Manganese (Mn) used as raw material for melting process in the ferrous foundry is considered as hazardous neurotoxic substance because it accumulates in the central nervous system and may cause neurological disorders. The furnace-men and melting department workers are potentially exposed to manganese particles or fume in the workplace. The objective of the research has been to investigate the sources and levels of manganese exposure in the foundry by correlation of blood-manganese (B-Mn) and air-manganese (air-Mn) measurement...
June 12, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28598939/impact-of-occupational-injuries-on-nonworkers-compensation-medical-costs-of-patient-care-workers
#19
Jessica A R Williams, Glorian Sorensen, Dean Hashimoto, Karen Hopcia, Gregory R Wagner, Leslie I Boden
OBJECTIVE: The aim of this study was to estimate the extent to which work-related injuries contribute to medical expenditures paid for by group health insurance. METHODS: Administrative data on OSHA recordable injuries spanning 2010 to 2013 were obtained for female patient care workers (n = 2495). Expenditures were aggregated group health insurance claims for 3 and 6-month periods before/after injury. Group health insurance plan type, age group, and job category were control variables...
June 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28585893/performance-of-two-respiratory-protective-devices-used-by-home-attending-health-care-workers-a-pilot-study
#20
Reported By Yousef Elmashae, Sergey A Grinshpun, Tiina Reponen, Michael Yermakov, Robert Riddle
OBJECTIVES: This pilot study aimed at determining the Workplace Protection Factor (WPF) for respiratory protective devices widely used by health care workers to reduce exposure to potentially hazardous aerosols when attending patients in their homes. Two devices were tested, an N95 filtering facepiece respirator (FFR) and a surgical mask (SM). METHODS: Three home-attending health care workers were recruited, medically cleared and fit tested. At the workplace, the aerosol concentrations outside (Cout) and inside (Cin) of the tested respiratory protective device worn by a subject were measured using two simultaneously operating P-Trak condensation particle counters within the particle size range of approximately 20-1,000 nm...
September 2017: Journal of Occupational and Environmental Hygiene
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