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Aristide Merola, Alberto Romagnolo, Michela Rosso, José Ricardo Lopez-Castellanos, Benjamin D Wissel, Sydney Larkin, Andrea Bernardini, Maurizio Zibetti, Simona Maule, Leonardo Lopiano, Alberto J Espay
INTRODUCTION: Orthostatic hypotension (OH) may frequently be asymptomatic in patients with Parkinson's disease (PD). However, the relationship between symptomatic/asymptomatic status and functional disability remains unclear. METHODS: Using orthostatic blood pressure (BP) measurements and the Orthostatic Hypotension Symptom Assessment (OHSA) questionnaire, 121 consecutive PD patients without history of chronic hypertension and not taking alpha-adrenergic antagonists for bladder disorders were classified according to (1) OH symptomatic status, based on presence/absence of orthostatic symptoms (symptomatic OH: OHSA item 1 ≥ 1), and (2) OH severity, based on the magnitude of BP fall on the lying-to-standing test: OH- (<20/10 mmHg); moderate OH+ (≥20/10 mmHg but < 30/15 mmHg); and severe OH+ (≥30/15 mmHg)...
September 10, 2016: Parkinsonism & related Disorders
Clément François, Gerald J Rowse, L Arthur Hewitt, Pamela Vo, Robert A Hauser
BACKGROUND: Droxidopa is an orally active prodrug that significantly improved dizziness/lightheadedness measured using the Orthostatic Hypotension Symptom Assessment (OHSA) Item 1 in patients with neurogenic orthostatic hypotension (nOH) caused by primary autonomic failure (Parkinson disease, multiple system atrophy, and pure autonomic failure), dopamine β-hydroxylase deficiency, or nondiabetic autonomic neuropathy. The efficacy and safety of droxidopa were assessed by determining the number needed to treat (NNT) and the number needed to harm (NNH)...
2016: BMC Neurology
Darko Palačić
The article contains the results of the research of impact of the implementation of the requirements mentioned in the Standard No. OHSAS 18001:2007 to reduce the number of injuries and the financial costs incurred in this way. The study was conducted on a determined sample by a survey method of a written questionnaire in the Republic of Croatia. The objective of the empirical research is to determine the impact of the implementation of requirements of Standard No. OHSAS 18001:2007 to reduce the number of injuries at work and financial costs in Croatia in business organizations that implement these requirements...
July 13, 2016: International Journal of Occupational Safety and Ergonomics: JOSE
Dejana Dejanović, Milenko Heleta
Occupational health and safety represents a set of technical, medical, legal, psychological, pedagogical and other measures with the aim to detect and eliminate hazards that threaten the lives and health of employees. These measures should be applied in a systematic way. Therefore, the aim of this study is to review occupational health and safety legislation in Serbia and the requirements that airports should fulfill for Occupational Health and Safety Assessment Series certification. Analyzing the specificity of airport activities and injuries as their outcomes, the article also proposes preventive measures for the health and safety of employees...
September 2016: International Journal of Occupational Safety and Ergonomics: JOSE
Abolfazl Ghahramani
Many organizations worldwide have implemented Occupational Health and Safety Assessment Series (OHSAS) 18001 in their premises because of the assumed positive effects of this standard on safety. Few studies have analyzed the effect of the safety climate in OHSAS 18001-certified organizations. This case-control study used a new safety climate questionnaire to evaluate three OHSAS 18001-certified and three non-certified manufacturing companies in Iran. Hierarchical regression indicated that the safety climate was influenced by OHSAS implementation and by safety training...
September 2016: International Journal of Occupational Safety and Ergonomics: JOSE
Sunku Venkata Siva Rajaprasad, Pasupulati Venkata Chalapathi
BACKGROUND: Construction activity has made considerable breakthroughs in the past two decades on the back of increases in development activities, government policies, and public demand. At the same time, occupational health and safety issues have become a major concern to construction organizations. The unsatisfactory safety performance of the construction industry has always been highlighted since the safety management system is neglected area and not implemented systematically in Indian construction organizations...
September 2015: Safety and Health At Work
Joe-Steve Annan, Emmanuel K Addai, Samuel K Tulashie
Occupational health and safety (OHS) is a broad field of professional practice, which involves specialists from different disciplines including but not limited to engineers, occupational health physicians, physical and biological scientists, economists, and statisticians. The preventive systems required to ensure workers are protected from injuries and illnesses dwell heavily on engineers; however, the extent to which the engineer can go regarding planning and implementing preventive measures is dependent on specific legal requirements, leadership commitment from the company, organization, and nation...
June 2015: Safety and Health At Work
M Maciążek-Jurczyk, A Sułkowska, J Równicka-Zubik
Changes of oxidative modified albumin conformation by comparison of non-modified (HSA) and modified (oHSA) human serum albumin absorption spectra, Red Edge Excitation Shift (REES) effect and fluorescence synchronous spectra were investigated. Studies of absorption spectra indicated that changes in the value of absorbance associated with spectral changes in the region from 200 to 250nm involve structural alterations related to variations in peptide backbone conformation. Analysis of the REES effect allowed for the observation of changes caused by oxidation in the region of the hydrophobic pocket containing the tryptophanyl residue...
January 5, 2016: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Irene Thiede, Michael Thiede
BACKGROUND: This study is the first cost-benefit analysis (CBA) of occupational health and safety (OHS) in a low-income country. It focuses on one of the largest shipbuilding companies in Bangladesh, where globally recognised Occupational Health and Safety Advisory Services (OHSAS) 18001 certification was achieved in 2012. OBJECTIVES: The study examines the relative costs of implementing OHS measures against qualitative and quantifiable benefits of implementation in order to determine whether OHSAS measures are economically advantageous...
2015: International Journal of Occupational and Environmental Health
Robert A Hauser, Stuart Isaacson, Jerome P Lisk, L Arthur Hewitt, Gerry Rowse
Neurogenic orthostatic hypotension (nOH) results from failure of norepinephrine responses to postural change to maintain standing systolic blood pressure (s-SBP). Droxidopa is an oral prodrug of norepinephrine. Study nOH306 enrolled patients with Parkinson's disease (PD) and symptomatic nOH. Subjects underwent up to 2 weeks of double-blind titration of droxidopa or placebo, followed by 8 weeks of double-blind maintenance treatment (100-600 mg thrice-daily). For the initial 51 subjects (study nOH306A, previously reported), the primary efficacy measure, Orthostatic Hypotension Questionnaire (OHQ) composite score, did not demonstrate significant change versus placebo at maintenance week 8...
April 15, 2015: Movement Disorders: Official Journal of the Movement Disorder Society
M Maciążek-Jurczyk, A Sułkowska
Oxygen metabolism has an important role in the pathogenesis of rheumatoid arthritis (RA). Reactive oxygen species (ROS) are produced in the course of cellular oxidative phosphorylation and by activated phagocytic cells during oxidative bursts, exceed the physiological buffering capacity and result in oxidative stress. ROS result in oxidation of serum albumin, which causes a number of structural changes in the spatial structure, may influence the binding and cause significant drug interactions, particularly in polytherapy...
February 5, 2015: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Amin Yazdani, W Patrick Neumann, Daniel Imbeau, Philip Bigelow, Mark Pagell, Nancy Theberge, Margo Hilbrecht, Richard Wells
OBJECTIVES: Musculoskeletal disorders (MSD) are a major cause of pain, disability, and costs. Prevention of MSD at work is frequently described in terms of implementing an ergonomics program, often a participatory ergonomics (PE) program. Most other workplace injury prevention activities take place under the umbrella of a formal or informal occupational health and safety management system (OHSMS). This study assesses the similarities and differences between OHSMS and PE as such knowledge could help improve MSD prevention activities...
March 2015: Scandinavian Journal of Work, Environment & Health
Miguel Valcárcel, Rafael Lucena
This paper describes the mutual impact of Analytical Chemistry and several international written standards (norms and guides) related to knowledge management (CEN-CWA 14924:2004), social responsibility (ISO 26000:2010), management of occupational health and safety (OHSAS 18001/2), environmental management (ISO 14001:2004), quality management systems (ISO 9001:2008) and requirements of the competence of testing and calibration laboratories (ISO 17025:2004). The intensity of this impact, based on a two-way influence, is quite different depending on the standard considered...
July 25, 2013: Analytica Chimica Acta
M Fusato
The report presents the experience in a steel company to improve the management of issues relating to health and safety of workers. The first part of the work focuses on the description of the interventions made by the company in recent years, which can be divided into technical interventions on production facilities, training and information, organizational activities and specific projects in collaboration with the health service. The second part presents the certification project according to OHSAS 18001, with particular focus on the efforts for a lean management of the documentation required by the management systems and for the automation of internal processes...
July 2012: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
F Pugliese, E Albini, O Serio, P Apostoli
The 81/2008 Act has defined a model of a health and safety management system that can contribute to prevent the occupational health and safety risks. We have developed the structure of a health and safety management system model and the necessary tools for its implementation in health care facilities. The realization of a model is structured in various phases: initial review, safety policy, planning, implementation, monitoring, management review and continuous improvement. Such a model, in continuous evolution, is based on the responsibilities of the different corporate characters and on an accurate analysis of risks and involved norms...
July 2011: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
Agnaldo Fernando Vieira de Arruda, Leila Maral Gontijo
The underground mining activity is regarded as one of the activities that cause most accidents, deaths and illnesses in the world, highlighting the coal mines. This study examined how ergonomics principles can help improve this environment, reduce the number of accidents and occupational diseases, train and empower workers and leaders and humanize the activities of the duty cycle of an underground mine. For this, it was developed a conceptual model of safety managing and health at work for the underground mining through the incorporation of ergonomics principles in the Occupational Safety and Health Management System and OHSAS 18001 (2007)...
2012: Work: a Journal of Prevention, Assessment, and Rehabilitation
Helenara Salvati Bertolossi Moreira, Bruna Talini, Isabele Maia Galvão, José Mohamud Vilagra, Eduardo Gallas Leivas, Abel Santos de Oliveira
UNLABELLED: To be distinguished from other companies, organizations are searching norms of certifications, such as ISO 9001, OHSAS 18001 and BS 8.800 to become more competitive in the work market, offering health and safety to the worker and quality to the customer. This extends the performance field of the Physiotherapist, who can use their knowledge to favor the processes of implementation of these certifications. The present work aims to identify the performance of the Physiotherapist in such processes of certification, as well as to verify their knowledge concerning the norms of certification and the performance in the occupational environment...
2012: Work: a Journal of Prevention, Assessment, and Rehabilitation
Fabrício Kurman Merlin, Vera Lúciaduarte do Valle Pereira, Waldemar Pacheco
Organizations are part of an environment in which they are pressured to meet society's demands and acting in a sustainable way. In an attempt to meet such demands, organizations make use of various management tools, among which, ISO standards are used. Although there are evidences of contributions provided by these standards, it is questionable whether its parameters converge for a possible induction for sustainable development in organizations. This work presents a theoretical study, designed on structuralism world view, descriptive and deductive method, which aims to analyze the convergence of management tools' parameters in ISO standards...
2012: Work: a Journal of Prevention, Assessment, and Rehabilitation
Beatriz Fernández-Muñiz, José Manuel Montes-Peón, Camilo José Vázquez-Ordás
The occupational health and safety standard OHSAS 18001 has gained considerable acceptance worldwide, and firms from diverse sectors and of varying sizes have implemented it. Despite this, very few studies have analysed safety management or the safety climate in OHSAS 18001-certified organisations. The current work aims to analyse the safety climate in these organisations, identify its dimensions, and propose and test a structural equation model that will help determine the antecedents and consequences of employees' safety behaviour...
March 2012: Accident; Analysis and Prevention
P Apostoli, F Pugliese
From many years the quality systems and the occupational prevention have been compared and connected both on theoretical and practical fields. The opportunity to discuss again and to deepen these themes appears to be mandatory to be able to govern the new working processes which shall follow the worldwide financial and productive crisis of last period and in our country to try to adequately apply the preventive norms 81/08 and 106/09. In this contribution we will deal with quality systems more intertwined with prevention (ISO 14000, EMAS, SA8000 and OHSAS 18001 and discuss in particular the role of with occupational physician in his meaning of global consultant for enterprise, a crucial technical figure in a typical multidisciplinary process as the implementation of the quality systems...
October 2010: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
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