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Strongyloides stercoralis

Natane Barbosa Barcelos, Lorena de Freitas E Silva, Regyane Ferreira Guimarães Dias, Hélio Ranes de Menezes Filho, Rosângela Maria Rodrigues
Patients infected with the Human Immunodeficiency Virus (HIV) often have opportunistic infections, among which strongyloidiasis and coccidiosis are the most common parasitic infections that aggravate their health status. This study examined the prevalence of intestinal parasites, particularly of Strongyloides stercoralis and intestinal coccidia in patients with the Human Immunodeficiency Virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDS) who were treated at the Specialized Assistance Service (SAE) of Jataí, State of Goiás, Brazil, and analyzed its correlation with clinical, laboratory, and socio-epidemiological parameters...
March 8, 2018: Revista do Instituto de Medicina Tropical de São Paulo
Pisit Suntaravitun, Amornrat Dokmaikaw
Intestinal parasitic infections remain a major public health problem in many parts of Thailand, particularly in rural areas. This study aimed to determine the prevalence of intestinal parasitic infections and associated risk factors among the people living in Huai Sai sub-district, Bang Khla district, Chachoengsao Province, central Thailand. A cross-sectional survey was carried out from June 2017 to August 2017 which included a total of 224 participants. Stool samples were examined using a simple direct smear and formalin ethyl acetate concentration technique...
February 2018: Korean Journal of Parasitology
Carolina Valença Barbosa, Magali Muniz Barreto, Rosemary de Jesus Andrade, Fernando Sodré, Claudia Masini d'Avila-Levy, José Mauro Peralta, Ricardo Pereira Igreja, Heloisa Werneck de Macedo, Helena Lucia Carneiro Santos
BACKGROUND: Intestinal parasitic infections are considered a serious public health problem and widely distributed worldwide, mainly in urban and rural environments of tropical and subtropical countries. Globally, soil-transmitted helminths and protozoa are the most common intestinal parasites. Blastocystis sp. is a highly prevalent suspected pathogenic protozoan, and considered an unusual protist due to its significant genetic diversity and host plasticity. METHODOLOGY/MAIN FINDINGS: A total of 294 stool samples were collected from inhabitants of three rural valleys in Rio de Janeiro, Brazil...
2018: PloS One
Francisca A Abanyie, Emily Valice, Kristin W Delli Carpini, Elizabeth B Gray, Isabel McAuliffe, Peter V Chin-Hong, Sukwan Handali, Susan P Montgomery, Shirish Huprikar
BACKGROUND: Targeted donor screening for strongyloidiasis performed at the time of organ procurement can prevent this life-threatening donor-derived infection. METHOD: The Association of Organ Procurement Organizations surveyed members to determine the number of U.S. organ procurement organizations (OPOs) performing donor screening for Strongyloides infection and their screening practices. RESULTS: All 58 OPOs responded to the survey. Only six (10%) currently screen donors for strongyloidiasis; most OPOs started 6-36 months before the survey, one started 6 years prior...
March 7, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
Paola L Minciullo, Antonio Cascio, Sebastiano Gangemi
BACKGROUND: The association between parasites and urticaria was first suggested in the last century. A wide range, 0-75.4%, of the prevalence of parasitic infection has been reported with chronic urticaria (CU). Moreover, urticaria may be detected in patients with parasitosis. Nematodes are a type of helminth that infect hundreds of millions of people throughout the world. OBJECTIVE: The aim of this work was to collect and review the published studies and cases of urticaria associated with nematode infections...
March 1, 2018: Allergy and Asthma Proceedings:
Anuradha Rajamanickam, Saravanan Munisankar, Yukthi Bhootra, Chandra Kumar Dolla, Thomas B Nutman, Subash Babu
Infection with the helminth parasite Strongyloides stercoralis ( Ss ) is commonly clinically asymptomatic that is often accompanied by peripheral eosinophilia. Granulocytes are activated during helminth infection and can act as immune effector cells. Plasma levels of eosinophil and neutrophil granular proteins convey an indirect measure of granulocyte degranulation and are prominently augmented in numerous helminth-infected patients. In this study, we sought to examine the levels of eosinophil, neutrophil, and mast cell activation-associated granule proteins in asymptomatic Ss infection and to understand their kinetics following anthelmintic therapy...
2018: Frontiers in Immunology
Angela Martinez-Perez, Silvia Roure Díez, Moncef Belhasen-Garcia, Diego Torrús-Tendero, Jose Luis Perez-Arellano, Teresa Cabezas, Cristina Soler, Marta Díaz-Menéndez, Miriam Navarro, Begoña Treviño, Fernando Salvador-Vélez
INTRODUCTION: Strongyloides stercoralis is a globally distributed nematode that causes diverse clinical symptoms in humans. Spain, once considered an endemic country, has experienced a recent increase in imported cases. The introduction of serology helps diagnosis and is currently replacing microbiological techniques in some settings, but its sensitivity is variable and can be low in immunocompromised patients. Diagnosis can only be confirmed by identification of larvae. Often, this "gold standard" can only be achieved in severe cases, such as disseminated S...
February 23, 2018: PLoS Neglected Tropical Diseases
Sun Yue, Liang Min
This paper reports the diagnosis and treatment of one rare case of thyroid dysfunction caused by Strongyloides stercoralis infection.
April 27, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
C Ocaña-Losada, J A Cuenca-Gómez, M T Cabezas-Fernández, J Vázquez-Villegas, M J Soriano-Pérez, I Cabeza-Barrera, J Salas-Coronas
OBJECTIVES: Blastocystis hominis (B. hominis) is one of the most common intestinal parasites isolated in humans. The parasite can cause gastrointestinal symptoms or, in most cases, remain asymptomatic. There are issues concerning the parasite's pathogenic character. The aim of this study was to analyse the clinical and epidemiological characteristics of the parasite infection by B. hominis, with or without other parasitic co-infections. PATIENTS AND METHODS: An observational retrospective study was conducted of B...
February 15, 2018: Revista Clínica Española
Kevin L Winthrop, Xavier Mariette, Jose T Silva, Esther Benamu, Leonard H Calabrese, Alexandre Dumusc, Josef S Smolen, José María Aguado, Mario Fernández-Ruiz
BACKGROUND: The present review is part of the ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies. AIMS: To review, from an Infectious Diseases perspective, the safety profile of agents targeting interleukins, immunoglobulins and complement factors and to suggest preventive recommendations. SOURCES: Computer-based MEDLINE searches with MeSH terms pertaining to each agent or therapeutic family...
February 12, 2018: Clinical Microbiology and Infection
Dora Buonfrate, Ana Requena-Mendez, Andrea Angheben, Michela Cinquini, Mario Cruciani, Andrea Fittipaldo, Giovanni Giorli, Federico Gobbi, Chiara Piubelli, Zeno Bisoffi
BACKGROUND: Strongyloides stercoralis infection is a neglected tropical disease which can lead to severe symptoms and even death in immunosuppressed people. Unfortunately, its diagnosis is hampered by the lack of a gold standard, as the sensitivity of traditional parasitological tests (including microscopic examination of stool samples and coproculture) is low. Hence, alternative diagnostic methods, such as molecular biology techniques (mostly polymerase chain reaction, PCR) have been implemented...
February 9, 2018: PLoS Neglected Tropical Diseases
Jason Blitz, Mark S Riddle, Chad K Porter
Background: Infectious gastroenteritis (IGE) is caused by numerous bacterial, viral, and parasitic pathogens. A history of IGE has been shown in previous studies to increase the risk of developing chronic gastrointestinal disorders and other chronic conditions. As bacteria and viruses represent the majority of pathogen-specific causes of IGE, post-infectious studies have primarily focused on these organisms. The objective of this study was to investigate an association between a history of parasite-associated IGE and the subsequent development of chronic post-infectious gastrointestinal and non-gastrointestinal disorders in a military population...
2018: Frontiers in Microbiology
Federica Sauda, Livia Malandrucco, Gladia Macrì, Manuela Scarpulla, Claudio De Liberato, Giuliana Terracciano, Gianluca Fichi, Federica Berrilli, Stefania Perrucci
Prevalence and risk factors of Leishmania infantum, Dirofilaria spp. and other potentially zoonotic or canine-specific endoparasite infections were assessed in 639 kennel dogs from central Italy. To this end, individual blood and fecal samples were examined using parasitological, immunological and molecular techniques. The presence of compatible clinical pictures, as well as age and gender were considered as putative risks factors. To evaluate risk factors, multivariable analysis with logistic regression and univariable analysis with a Chi square test and a Fischer's exact test were performed...
2018: Parasite: Journal de la Société Française de Parasitologie
Pedro Puerta-Alcalde, Joan Gomez-Junyent, Ana Requena-Mendez, Maria Jesús Pinazo, Miriam José Álvarez-Martínez, Natalia Rodríguez, Joaquim Gascon, Jose Muñoz
BACKGROUND: We evaluate the association between Trypanosoma cruzi infection and strongyloidiasis in a cohort of Latin American (LA) migrants screened for both infections in a non-endemic setting. METHODOLOGY: Case-control study including LA individuals who were systematically screened for T. cruzi infection and strongyloidiasis between January 2013 and April 2015. Individuals were included as cases if they had a positive serological result for Strongyloides stercoralis...
January 2018: PLoS Neglected Tropical Diseases
Elena Dacal, José M Saugar, Aida de Lucio, Marta Hernández-de-Mingo, Elena Robinson, Pamela C Köster, María L Aznar-Ruiz-de-Alegría, Mateu Espasa, Arlette Ninda, Javier Gandasegui, Elena Sulleiro, Milagros Moreno, Fernando Salvador, Israel Molina, Esperanza Rodríguez, David Carmena
BACKGROUND: Human infections by the gastrointestinal helminth Strongyloides stercoralis and the enteric protozoans Giardia duodenalis, Cryptosporidium spp. and Blastocystis spp. are not formally included in the list of 20 neglected tropical diseases prioritised by the World Health Organization. Although largely underdiagnosed and considered of lower public health relevance, these infections have been increasingly demonstrated to cause significant morbidity and even mortality globally, particularly among children living in resource-poor settings...
January 29, 2018: Parasites & Vectors
Lucas J Cunningham, John Odoom, Deborah Pratt, Linda Boatemaa, Nana Asante-Ntim, Keren Attiku, Bismarck Banahene, Mike Osei-Atweneboana, Jaco J Verweij, David Molyneux, Russell J Stothard, Emily R Adams
The efforts to control and eradicate polio as a global health burden have been successful to the point where currently only three countries now report endemic polio, and the number of cases of polio continues to decrease. The success of the polio programme has been dependant on a well-developed network of laboratories termed the global polio laboratory network (GPLN). Here we explore collaborative opportunities with the GPLN to target two of the 18 diseases listed as a neglected tropical diseases (NTD) namely soil transmitted helminthiasis (STH) and Schistosomiasis (SCH)...
January 2018: PLoS Neglected Tropical Diseases
Beatrice Barda, Rahel Wampfler, Somphou Sayasone, Khampheng Phongluxa, Syda Xayavong, Khonsavanh Keoduangsy, Christian Schindler, Jennifer Keiser
INTRODUCTION: Strongyloides stercoralis is present worldwide, but its prevalence is still uncertain, mainly due to the lack of sensitivity of diagnostic methods. Molecular techniques are under development, but a standardized protocol is still unavailable. We compared the sensitivity of real time PCR, using two extraction protocols, with the Baermann technique. MATERIALS AND METHODS: Samples were collected in the framework of the baseline screening of a randomized clinical trial evaluating moxidectin against S...
January 24, 2018: Journal of Clinical Microbiology
Buravej Assavapongpaiboon, Uthaitip Bunkasem, Vivornpun Sanprasert, Surang Nuchprayoon
Intestinal parasitic infection rate among school-aged children in Thailand has been decreasing. However, certain intestinal parasites remain problematic in some regions. This cross-sectional study was conducted between February and September 2016 in three suburban government primary schools (KK, BR, and HK), Saraburi, Thailand. Stool was collected from 263 asymptomatic subjects (4-15 years old), using simple direct smear, formalin-ether concentration, Boeck and Drbohlav's Locke-Egg-Serum (LES) medium culture, and agar plate culture...
January 22, 2018: American Journal of Tropical Medicine and Hygiene
Silvia A Repetto, Paula Ruybal, Estela Batalla, Carlota López, Vanesa Fridman, Mariela Sierra, Marcelo Radisic, Pablo M Bravo, Marikena G Risso, Stella M González Cappa, Catalina D Alba Soto
Background: Strongyloides stercoralis affects 30-100 million people worldwide. The first-line therapy is ivermectin. Cure is defined as the absence of larvae by parasitological methods 1 year after treatment. To date, no longitudinal parasitological studies for longer periods of time have been conducted to confirm its cure. Here, we evaluated treatment response in long-term follow-up patients with chronic infection using parasitological and molecular methods for larvae or DNA detection...
January 19, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Massini Merzkani, Nupur N Uppal, Daniel W Ross, Pranisha Gautam-Goyal, Prashant Malhotra, Hitesh H Shah, Kenar D Jhaveri, Vivette D D'Agati
No abstract text is available yet for this article.
January 2018: KI Reports
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