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Strongyloides stercoralis

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https://www.readbyqxmd.com/read/27903301/high-prevalence-of-strongyloides-stercoralis-in-school-aged-children-in-a-rural-highland-of-north-western-ethiopia-the-role-of-intensive-diagnostic-work-up
#1
Aranzazu Amor, Esperanza Rodriguez, José M Saugar, Ana Arroyo, Beatriz López-Quintana, Bayeh Abera, Mulat Yimer, Endalew Yizengaw, Derejew Zewdie, Zimman Ayehubizu, Tadesse Hailu, Wondemagegn Mulu, Adriana Echazú, Alejandro J Krolewieki, Pilar Aparicio, Zaida Herrador, Melaku Anegagrie, Agustín Benito
BACKGROUND: Soil-transmitted helminthiases (hookworms, Ascaris lumbricoides and Trichuris trichiura) are extremely prevalent in school-aged children living in poor sanitary conditions. Recent epidemiological data suggest that Strongyloides stercoralis is highly unreported. However, accurate data are essential for conducting interventions aimed at introducing control and elimination programmes. METHODS: We conducted a cross-sectional survey of 396 randomly selected school-aged children in Amhara region in rural area in north-western Ethiopia, to assess the prevalence of S...
December 1, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27884406/-clinical-approach-to-imported-eosinophilia
#2
Elías Cañas García-Otero, Julia Praena-Segovia, Maite Ruiz-Pérez de Pipaón, Xerach Bosh-Guerra, Magdalena Sánchez-Agüera, Daniel Álvarez-Martínez, José Miguel Cisneros-Herreros
Eosinophilia is a common finding in international travelers and immigrants, being an helmintic infection its main etiology. The positive predictive value of eosinophilia for an helmintosis is low in travellers. Eosinophilia may be an incidental finding, or symptomatic, and it represents a clinical challenge due to the low sensitivity and specificity of direct and indirect parasitological diagnostic tests, respectively. It requires a structured approach based on geographical areas, environmental exposures and behavioral risks, and associated symptoms...
December 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27877170/comparison-of-s-stercoralis-serology-performed-on-dried-blood-spots-and-on-conventional-serum-samples
#3
Fabio Formenti, Dora Buonfrate, Rosanna Prandi, Monica Marquez, Cintia Caicedo, Eleonora Rizzi, Angel G Guevara, Yosselin Vicuña, Francisco R Huerlo, Francesca Perandin, Zeno Bisoffi, Mariella Anselmi
Background: Dried blood spots (DBS) are used for epidemiological surveys on infectious diseases in settings where limited resources are available. In fact, DBS can help to overcome logistic difficulties for the collection, transport and storage of biological specimens. Objective: To evaluate the accuracy of Strongyloides stercoralis serology performed on DBS. Methods: A survey was proposed to children attending a school in the village of Borbon, Ecuador, and to their parents/guardians. Each participant gave consent to the collection of both serum and DBS specimens...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27876945/a-case-of-fatal-gastrointestinal-haemorrhage-due-to-hyperinfection-with-strongyloides-stercoralis
#4
Dina Abdallah Zaghlool, Amal Ali Hassan, Asmaa Moustafa Moustafa, Wael Ahmed Shahin
Strongyloides stercoralis is an intestinal nematode with a complex life cycle. It is usually asymptomatic in healthy host however it may be a life threatening condition in immunocompromised patients when hyperinfection is associated with disseminated disease. However, reports of gastric involvement are rare. This is a case report of fatal gastrointestinal hemorrhage due to hyperinfection with S. stercoralis in a Burmawi male patient after brief corticosteroid therapy.
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27862705/screening-of-living-organ-donors-for-endemic-infections-understanding-the-challenges-and-benefits-of-enhanced-screening
#5
REVIEW
Amanda Rosen, Michael G Ison
Living organ donor candidates are screened for medical and psychosocial contraindications to donation. One important goal of this process is to prevent donor-derived infectious diseases transmissions. These transmissions are exceptionally rare, but have the potential to cause significant morbidity and mortality. The Organ Procurement and Transplantation Network now requires each recovery hospital to develop a protocol for evaluating living donors for tuberculosis and other geographically-defined endemic pathogens, including Trypanosoma cruzi (the causative pathogen of Chagas' disease), Strongyloides stercoralis, and West Nile Virus (WNV), in addition to universal screening for blood-borne pathogens...
November 14, 2016: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/27860061/strongyloides-hyperinfection-following-hematopoietic-stem-cell-transplant-in-a-patient-with-htlv-1-associated-t-cell-leukemia
#6
Jonathan D Alpern, Sophie S Arbefeville, Gregory Vercellotti, Patricia Ferrieri, Jaime S Green
Strongyloides stercoralis has the potential to cause accelerated autoinfection in immunocompromised hosts. Screening tests for strongyloidiasis may be falsely negative in the setting of immunosuppression. We report a case of Strongyloides hyperinfection syndrome in a patient with human T-lymphotropic virus type 1-associated T-cell leukemia early after hematopoietic stem cell transplant. The diagnosis was made by stool ova and parasite examination, despite a negative screening enzyme-linked immunosorbent assay...
November 17, 2016: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/27853126/epidemiological-characteristics-of-strongyloidiasis-in-inhabitants-of-indigenous-communities-in-borneo-island-malaysia
#7
Romano Ngui, Noor Amira Abdul Halim, Yamuna Rajoo, Yvonne Al Lim, Stephen Ambu, Komalaveni Rajoo, Tey Siew Chang, Lu Chan Woon, Rohela Mahmud
Epidemiological study on strongyloidiasis in humans is currently lacking in Malaysia. Thus, a cross-sectional study was carried out to determine the prevalence of Strongyloides stercoralis infection among the inhabitants of longhouse indigenous communities in Sarawak. A single stool and blood sample were collected from each participant and subjected to microscopy, serological and molecular techniques. Five species of intestinal parasites were identified by stool microscopy. None of the stool samples were positive for S...
October 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/27821584/microbial-translocation-associated-with-an-acute-phase-response-and-elevations-in-mmp-1-ho-1-and-pro-inflammatory-cytokines-in-strongyloides-stercoralis-infection
#8
Anuradha Rajamanickam, Saravanan Munisankar, Yukthi Bhootra, Chandrakumar Dolla, Thomas B Nutman, Subash Babu
Microbial translocation, characterized by elevated levels of lipopolysaccharide (LPS) and related markers, is a common occurrence in HIV and some parasitic infections. This is usually associated with extensive inflammation and immune activation. To examine the occurrence of microbial translocation and the associated inflammatory response in asymptomatic, Strongyloides stercoralis (Ss) infection, we measured the plasma levels of LPS and other microbial translocation markers, acute-phase proteins, inflammatory markers, and pro-inflammatory cytokines in individuals with (INF) or without (UN) Ss infections...
November 7, 2016: Infection and Immunity
https://www.readbyqxmd.com/read/27795876/a-study-of-parasitic-and-bacterial-pathogens-associated-with-diarrhea-in-hiv-positive-patients
#9
Siddharth Shah, Vaishali Kongre, Varun Kumar, Renu Bharadwaj
INTRODUCTION: Diarrhea is a common complication of acquired immune deficiency syndrome (AIDS), occurring in almost 90% of AIDS patients in developing countries like India. The present study was aimed to determine the prevalence and microbiological profile of pathogens associated with diarrhea in human immunodeficiency virus (HIV) positive patients and their relation to CD4 counts. MATERIALS AND METHODS: Forty-five successive HIV-positive patients, 27 with diarrhea (study group) and 18 without diarrhea (control group), were included in the three-month study...
September 27, 2016: Curēus
https://www.readbyqxmd.com/read/27790963/comparison-between-merthiolate-iodine-formalin-and-kato-katz-methods-for-the-diagnosis-of-human-helminth-infections-in-resource-limited-settings
#10
R N Incani, T Homan, E Pinelli, L Mughini-Gras, H Guevara, J Jesus
Diagnosis of intestinal parasites through examination of fresh faecal samples is hampered by its unpleasantness and the urgent need to detect all parasitic forms. In this paper, we compared the standard Kato-Katz (KK) technique with a traditional fixation method, the merthiolate-iodine-formalin (MIF) method. Two hundred and twenty-seven faecal samples from individuals living in a rural setting in Venezuela with high to moderate prevalences of Ascaris lumbricoides (Al), Trichuris trichiura (Tt) and hookworm infections were examined...
October 28, 2016: Journal of Helminthology
https://www.readbyqxmd.com/read/27771420/alterations-in-serum-paraoxonase-1-activity-and-lipid-profile-in-chronic-alcoholic-patients-infected-with-strongyloides-stercoralis
#11
Elizabete de Jesus Inês, Mônica Lopes Sampaio Silva, Joelma Nascimento de Souza, Alana Alcântara Galvão, Márcia Cristina Aquino Teixeira, Neci Matos Soares
The objective of this study was to investigate paraoxonase-1 (PON1) activity, cortisol levels, and the lipid profile in the sera of alcoholic and non-alcoholic Strongyloides stercoralis-infected and uninfected individuals in a sample of 276 individuals attended at the National Health System in Salvador, Bahia, Brazil. The activity of PON1 was measured by the Beltowski method, serum lipids, and cortisol levels using commercial kits. PON1 activity was low in both alcoholic and non-alcoholic individuals infected with S...
October 19, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27769813/current-progress-toward-vaccine-and-passive-immunization-approaches-for-strongyloides-spp
#12
REVIEW
Marcelo Arantes Levenhagen, Hélio Conte, Julia Maria Costa-Cruz
Strongyloides stercoralis is a helminth parasite that can infect millions of people worldwide, particularly in tropical, subtropical and temperate regions with poor sanitation. Several aspects of epidemiology, biology and host-parasite interactions of S. stercoralis have been studied, and substantial knowledge has been acquired; however, very few studies on immunotherapeutic control strategies to prevent infection and disease in humans have been conducted. Therefore, this article reviews the current progress and targets toward vaccine and passive immunization approaches for Strongyloides spp...
October 18, 2016: Immunology Letters
https://www.readbyqxmd.com/read/27744050/normal-serum-ige-levels-and-eosinophil-counts-exhibited-during-strongyloides-stercoralis-infection
#13
Miwa Higashiarakawa, Tetsuo Hirata, Teruhisa Tanaka, Gretchen Parrott, Tetsu Kinjo, Hidekatsu Naka, Akira Hokama, Jiro Fujita
Infections with parasites, such as Strongyloides stercoralis, typically cause elevated levels of serum immunoglobulin E (IgE) and eosinophils; however, co-infection with human T cell lymphotropic virus type 1 (HTLV-1) can cause lower levels of serum IgE during S. stercoralis infection. We conducted this study to determine whether serum IgE levels and eosinophil counts could also be related to other patient characteristics or symptoms. Between 1991 and 2014, we measured and compared the symptoms of 237 patients and evaluated serum IgE levels and eosinophil counts of 199 patients who were infected with S...
October 12, 2016: Parasitology International
https://www.readbyqxmd.com/read/27743682/-strongyloides-stercoralis-infection-in-a-spanish-regional-hospital-not-just-an-imported-disease
#14
María Isabel Pacheco-Tenza, José Antonio Ruiz-Maciá, María Navarro-Cots, Joan Gregori-Colomé, José María Cepeda-Rodrigo, Jara Llenas-García
INTRODUCTION: Strongyloides stercoralis infection is more prevalent in tropical regions but autochthonous cases have been reported in Spain, mainly in La Safor (Valencia). The objective is to describe the strongyloidiasis cases registered in a regional hospital of Alicante province (Spain) and to determine if they were autochthonous cases. METHODS: Retrospective study of all diagnosed cases of strongyloidiasis in Vega Baja Hospital (Orihuela, Alicante) between January 1999 and March 2016...
October 12, 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27742318/donor-derived-strongyloidiasis-infection-in-solid-organ-transplant-recipients-a-review-and-pooled-analysis
#15
J H Kim, D S Kim, Y K Yoon, J W Sohn, M J Kim
BACKGROUND: Donor-derived Strongyloides stercoralis infection in solid organ transplant (SOT) recipients is uncommon. Immunosuppressed SOT recipients are at risk of developing severe forms of strongyloidiasis infection through transmission from an infected donor allograft. METHODS: PubMed was searched for English-written articles published up to April 2015. Articles that reported cases of donor-derived strongyloidiasis infection in SOT recipients were reviewed for a pooled analysis...
September 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27716099/prevalence-of-intestinal-parasitic-infections-and-associated-risk-factors-among-pregnant-women-attending-antenatal-care-center-at-felege-hiwot-referral-hospital-northwest-ethiopia
#16
Adane Derso, Endalkachew Nibret, Abaineh Munshea
BACKGROUND: Parasitic infections affect tens of millions of pregnant women worldwide, and directly or indirectly lead to a spectrum of adverse maternal and fetal/placental effects. The objective of this study was to assess the prevalence of intestinal parasite infections and associated risk factors among pregnant women attending antenatal care center in Felege Hiwot Referral Hospital, Bahir Dar city, northwest Ethiopia. METHODS: A cross-sectional hospital based study was conducted from November 2013 to January 2014 among 384 pregnant women...
September 30, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27703835/strongyloides-hyperinfection-syndrome-combined-with-cytomegalovirus-infection
#17
Fatehi Elnour Elzein, Mohammed Alsaeed, Sulafa Ballool, Ashraf Attia
The mortality in Strongyloides hyperinfection syndrome (SHS) is alarmingly high. This is particularly common in bone marrow, renal, and other solid organ transplant (SOT) patients, where figures may reach up to 50-85%. Immunosuppressives, principally corticosteroids, are the primary triggering factor. In general, the clinical features of Strongyloides stercoralis hyperinfection are nonspecific; therefore, a high index of suspicion is required for early diagnosis and starting appropriate therapy. Although recurrent Gram-negative sepsis and meningitis have been previously reported, the combination of both cytomegalovirus (CMV) and strongyloidiasis had rarely been associated...
2016: Case Reports in Transplantation
https://www.readbyqxmd.com/read/27680168/diagnosis-of-strongyloides-stercoralis-infection-in-immunocompromised-patients-by-serological-and-molecular-methods
#18
Fabiana Martins de Paula, Fernanda Mello Malta, Marcelo Andreetta Corral, Priscilla Duarte Marques, Maiara Gottardi, Dirce Mary Correia Lima Meisel, Juliana Yamashiro, João Renato Rebello Pinho, Vera Lucia Pagliusi Castilho, Elenice Messias do Nascimento Gonçalves, Ronaldo César Borges Gryschek, Pedro Paulo Chieffi
Strongyloidiasis is a potentially serious infection in immunocompromised patients. Thus, the availability of sensitive and specific diagnostic methods is desirable, especially in the context of immunosuppressed patients in whom the diagnosis and treatment of strongyloidiasis is of utmost importance. In this study, serological and molecular tools were used to diagnose Strongyloides stercoralis infections in immunosuppressed patients. Serum and stool samples were obtained from 52 patients. Stool samples were first analyzed by Lutz, Rugai, and Agar plate culture methods, and then by a quantitative real time polymerase chain reaction (qPCR)...
2016: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/27672206/hymenolepis-nana-impact-among-children-in-the-highlands-of-cusco-peru-an-emerging-neglected-parasite-infection
#19
Miguel M Cabada, Maria Luisa Morales, Martha Lopez, Spencer T Reynolds, Elizabeth C Vilchez, Andres G Lescano, Eduardo Gotuzzo, Hector Hugo Garcia, Clinton A White
Hymenolepis nana is the most common cestode infection in the world. However, limited information is available regarding its impact on affected populations. We studied the epidemiology and symptoms associated with hymenolepiasis among children 3-16 years old in 16 rural communities of the highlands of the Cusco region in Peru. Information on demographics, socioeconomic status, symptoms as reported by parents, and parasitological testing was obtained from the database of an ongoing Fasciola hepatica epidemiologic study...
November 2, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27645607/incidental-identification-of-strongyloides-stercoralis-infection-by-broad-range-28s-rdna-gene-sequencing-in-a-patient-with-a-hematolymphoid-malignancy
#20
Eric Q Konnick, Siu-Kei Chow, Nicholas P Reder, Dhruba J Sengupta, Daniel R Hoogestraat, Paul S Pottinger, April N Abbott, Peter W Monsaas, Kyoko Kurosawa, Karen Stephens, Stephen J Salipante, Cecilia C S Yeung
Strongyloides stercoralis is an important human parasite, especially in rural areas and developing countries. Infected immunosuppressed patients are at risk for hyperinfection, with severe clinical consequences. Here we describe the incidental detection and diagnosis of an unexpected S. stercoralis infection by methods designed to detect fungal 28S ribosomal DNA.
September 4, 2016: Diagnostic Microbiology and Infectious Disease
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