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Strongyloides stercoralis

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https://www.readbyqxmd.com/read/28210503/strongyloidiasis-current-status-with-emphasis-in-diagnosis-and-drug-research
#1
REVIEW
Tiago Mendes, Karen Minori, Marlene Ueta, Danilo Ciccone Miguel, Silmara Marques Allegretti
Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/28182097/incidental-detection-of-strongyloides-stercoralis-in-a-routine-cervicovaginal-smear
#2
Sandeep P Kumar, Varuna Mallya
No abstract text is available yet for this article.
January 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28178325/prevalence-and-clinical-relevance-of-helminth-co-infections-among-tuberculosis-patients-in-urban-tanzania
#3
Francis Mhimbira, Jerry Hella, Khadija Said, Lujeko Kamwela, Mohamed Sasamalo, Thomas Maroa, Magreth Chiryamkubi, Grace Mhalu, Christian Schindler, Klaus Reither, Stefanie Knopp, Jürg Utzinger, Sébastien Gagneux, Lukas Fenner
BACKGROUND: Helminth infections can negatively affect the immunologic host control, which may increase the risk of progression from latent Mycobacterium tuberculosis infection to tuberculosis (TB) disease and alter the clinical presentation of TB. We assessed the prevalence and determined the clinical relevance of helminth co-infection among TB patients and household contact controls in urban Tanzania. METHODOLOGY: Between November 2013 and October 2015, we enrolled adult (≥18 years) sputum smear-positive TB patients and household contact controls without TB during an ongoing TB cohort study in Dar es Salaam, Tanzania...
February 8, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28167672/anthelmintic-therapy-modifies-the-systemic-and-mycobacterial-antigen-stimulated-cytokine-profile-in-helminth-latent-mycobacterium-tuberculosis-co-infection
#4
Rajamanickam Anuradha, Saravanan Munisankar, Yukthi Bhootra, Chandrakumar Dolla, Paul Kumaran, Thomas B Nutman, Subash Babu
Helminth infections are known to modulate cytokine responses in latent tuberculosis (LTB). However, very few studies have examined whether this modulation is reversible upon anthelmintic therapy. We measured the systemic and mycobacterial (TB) - antigen-stimulated levels of Type 1, Type 2, Type 17 and regulatory cytokines in individuals with LTB and with or without coexistent Strongyloides stercoralis (Ss) infection before and after anthelmintic therapy. Our data reveal that individuals with LTB and coexistent Ss infection have significantly lower levels of systemic and TB antigen-stimulated Type 1 (IFNγ, TNFα and IL-2) and Type 17 (IL-17A and/or IL-17F) cytokines and significantly higher levels of systemic but not TB antigen-stimulated Type 2 (IL-4 and IL-5) and regulatory (TGFβ) cytokines...
February 6, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28127364/prevalence-of-strongyloides-stercoralis-and-other-intestinal-parasites-among-institutionalized-mentally-disabled-individuals-in-rasht-northern-iran
#5
Amin Saeidinia, Ilnaz Tavakoli, Mohammad Reza Naghipour, Behnaz Rahmati, Hossein Ghavami Lahiji, Omid Salkhori, Keyhan Ashrafi
BACKGROUND: We aimed to determine the status of strongyloidiasis in mentally disabled population in the institutional places in Rasht City, the capital of Guilan Province, northern Iran. METHODS: This cross-sectional study was conducted in 8 institutions for mentally retarded population in Rasht in 2013. Before collecting the samples, a questionnaire was filled out for each participant by an expert person. A single stool sample was obtained from each of the 173 subjects and examined using direct wet mount, formalin-ether concentration technique and agar plate culture method...
October 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28127349/disseminated-strongyloidiasis-in-an-immunodeficient-patient-pemphigus-vulgaris-due-to-corticosteroid-therapy-a-case-report
#6
Mohsen Najjari, Mohammad Ebrahimipour, Amir Kaheh, Mohammadreza Karimazar
Strongyloidiasis is a frequent misdiagnosed parasitic infection in the world that caused by Strongyloides stercoralis. In Iran, the disease is predominantly reported from warm and humid climate provinces. The patient was a 54-yr-old man, originated from Khuzestan Province with a history of pemphigus and diabetes that was treated with high-dose of corticosteroid drugs before admission in a non-private hospital in Shiraz, Iran in 2014. After different primary diagnosis and administrating of several drugs, endoscopy and histopatholgical biopsy revealed a massive S...
July 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28124134/diagnosis-of-strongyloides-stercoralis-by-morphological-characteristics-combine-with-molecular-biological-methods
#7
Li-Fu Wang, Lian Xu, Shi-Qi Luo, Hui Xie, Wei Chen, Zhong-Dao Wu, Xi Sun
Strongyloidiasis is one of the neglected tropical diseases caused by infection with the nematode Strongyloides genus and distributed worldwide. Strongyloidiasis can be fatal in immunosuppressed patients induced hyperinfection or disseminated strongyloidiasis. Unfortunately, until now, due to the unspecific clinical symptom in infected individuals and the low sensitivity diagnosis of strongyloidiasis, many patients were misdiagnosed every year. Furthermore, the larvae of the Strongyloides stercoralis (S. stercoralis) is similar to other nematodes such as hookworm, Trichostrongylus increased the difficulty of diagnosis...
January 26, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28122583/abundance-zoonotic-potential-and-risk-factors-of-intestinal-parasitism-amongst-dog-and-cat-populations-the-scenario-of-crete-greece
#8
Despoina Kostopoulou, Edwin Claerebout, Dimitrios Arvanitis, Panagiota Ligda, Nikolaos Voutzourakis, Stijn Casaert, Smaragda Sotiraki
BACKGROUND: The objectives of this study were to evaluate the prevalence and infection intensity of intestinal parasites in different dog and cat populations in Crete, Greece, estimate the zoonotic risk and identify risk factors. METHODS: Faecal samples from shelter, household and shepherd dogs and shelter and household cats were analyzed using sedimentation/flotation techniques. Giardia and Cryptosporidium were detected by a quantitative direct immunofluorescence assay (IFA)...
January 25, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28115668/improved-detection-of-strongyloides-stercoralis-in-modified-agar-plate-cultures
#9
Leonor A Pocaterra, Giuseppe Ferrara, Rosaura Peñaranda, Elsy Rojas, Gladymar Pérez-Chacón, Aurora Hernán, Gabriela Certad, Carlos Goldstein, Luz Núñez
A modification of Koga agar plate culture was performed, consisting of a 2 × 2-cm cellophane paper centered on the agar plate to prevent bacterial contamination of the agar and daily dish examinations (days 2-5). Between January 2000 and July 2005, we examined 1,708 infection-suspected patients, of which 147 (8.6%) harbored S. stercoralis Single modified agar plate cultures exhibited superior sensitivity (93.2%), compared with different three-sample screening methods (sensitivity-Baermann: 76.6%, formalin-ethyl acetate: 22%, and direct smear: 15...
January 23, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28114314/diagnosing-polyparasitism-in-a-high-prevalence-setting-in-beira-mozambique-detection-of-intestinal-parasites-in-fecal-samples-by-microscopy-and-real-time-pcr
#10
Lynn Meurs, Anton M Polderman, Natalie V S Vinkeles Melchers, Eric A T Brienen, Jaco J Verweij, Bernhard Groosjohan, Felisberto Mendes, Manito Mechendura, Dagmar H Hepp, Marijke C C Langenberg, Rosanne Edelenbosch, Katja Polman, Lisette van Lieshout
BACKGROUND: Many different intestinal parasite species can co-occur in the same population. However, classic diagnostic tools can only frame a particular group of intestinal parasite species. Hence, one or two tests do not suffice to provide a complete picture of infecting parasite species in a given population. The present study investigated intestinal parasitic infections in Beira, Mozambique, i.e. in the informal settlement of Inhamudima. Diagnostic accuracy of five classical microscopy techniques and real-time PCR for the detection of a broad spectrum of parasites was compared...
January 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28112346/-strongyloidiasis-as-cause-of-lower-gastrointestinal-bleeding
#11
Patricia Paredes, Janeth Atiaja, Santiago Lanas
Intestinal parasites are a common pathology in the pediatric practice, constituting a major public health problem. Currently their epidemiology, especially in countries like Ecuador where there are populations and communities where health services are scarce or difficult to access. We report the case of a child with chronic grade 3 malnutrition, from Sarayacu province of Pastaza, Ecuador an endemic area in several parasitosis. The clinical features were lower gastrointestinal bleeding added to chronic anemia and eosinophilia...
October 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28112345/-pulmonary-strongyloidiasis
#12
Heiler Lozada, Jorge E Daza
Strongyloidiasis is an infection caused by the parasite Strongyloides stercoralis, which can be asymptomatic and means a high morbidity and mortality in immunocompromised hosts, severe malnutrition and coinfection with HTLV-1 virus. The parasite has the potential to produce and multiply internal autoinfection in humans, thus an hyperinfection can be developed. A case of pulmonary infection by this parasite is presented in this study, infection which advanced into a respiratory failure and required mechanical ventilation and hemodynamic support in an intensive care unit...
October 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28112060/parasitological-versus-molecular-diagnosis-of-strongyloidiasis-in-serial-stool-samples-how-many
#13
E Dacal, J M Saugar, T Soler, J M Azcárate, M S Jiménez, F J Merino, E Rodríguez
Strongyloidiasis is usually an asymptomatic disease in immunocompetent patients, caused by Strongyloides stercoralis. However, in immunocompromised patients it can produce a severe clinical profile. Therefore, a correct diagnosis is necessary in these cases and in those chronic asymptomatic patients. The low sensitivity of classical parasitological techniques requires the analysis of multiple serial stool samples. Molecular diagnostic techniques represent an improvement in the detection of the parasite. The objective of this study was to evaluate the minimum number of samples necessary to achieve maximum sensitivity by real-time polymerase chain reaction (PCR)...
January 23, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28096866/disseminated-strongyloidiasis-in-an-iranian-immunocompromised-patient-a-case-report
#14
Narges Najafi, Eissa Soleymani, Shahabeddin Sarvi, Amirkeivan Marofi, Anahita Nosrati, Alireza Davoodi
Strongyloides stercoralis is a soil-transmitted helminth (STH) widespread in various part of the world. A 78-yr-old peasant diabetic female from Mazandaran Province northern Iran, was admitted to Infection Department of the Razi Hospital in city of Qaemshahr, north of Iran complaining about abdominal skin rash, pruritus, itching, anorexia, nausea, vomiting, dysuria and cough. This patient had cutaneous migration effects of S. stercoralis larvae in her abdominal skin (larva currents and urticaria). Lung CT without contrast demonstrate s bilateral diffuse ground glass opacity draws attention...
April 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28093424/strongyloides-hyperinfection-syndrome-and-vre-pneumonia
#15
Mohannad Abu Omar, Mouhanna Abu Ghanimeh, Sola Kim, Gregory Howell
Immunocompromised patients have high risk of infections from bacteria, viruses, fungi and parasites. One of these infections is those caused by Strongyloides stercoralis Immunocompromised patients are at risk of hyperinfection syndrome which is characterised with more systemic manifestation and a higher risk of morbidity and mortality. This can be complicated by coinfection with enteric organisms, specifically Gram-negative. Enterococci are Gram-positive cocci which are inhabitants of the human gastrointestinal tract...
January 16, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28074315/the-roundworm-strongyloides-stercoralis-in-children-dogs-and-soil-inside-and-outside-a-segregated-settlement-in-eastern-slovakia-frequent-but-hardly-detectable-parasite
#16
G Štrkolcová, M Goldová, E Bocková, J Mojžišová
A comparative study was carried out to evaluate the Strongyloides stercoralis infections in children and dogs inside and outside the segregated settlement in Medzev, Eastern Slovakia, and a survey of the soil within the settlement was included. Applying the Koga agar plate (KAP) culture method and microscopy examination of stool samples collected from 60 Roma and 21 nonRoma children, no larvae of S. stercoralis were detected but eggs of three nematodes (Ascaris lumbricoides, Trichuris trichiura, and Enterobius vermicularis) and cysts of two protozoan endoparasites (Giardia duodenalis and Cryptosporidium spp...
January 10, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28073382/a-retrospective-study-comparing-agar-plate-culture-indirect-immunofluorescence-and-real-time-pcr-for-the-diagnosis-of-strongyloides-stercoralis-infection
#17
Dora Buonfrate, Francesca Perandin, Fabio Formenti, Zeno Bisoffi
Strongyloides stercoralis is a parasite that can cause death in immunocompromised people. A proper diagnosis is hence essential. The real-time polymerase-chain reaction (RT-PCR) is a novel, promising diagnostic method, that detects the DNA of the parasite in stool samples. In this retrospective study, we compared the sensitivity of agar plate coproculture (APC), an in-house immunofluorescence test (IFAT) and an in-house RT-PCR for the diagnosis of S. stercoralis infection. The study sample was composed by 223 samples...
January 11, 2017: Parasitology
https://www.readbyqxmd.com/read/28033376/genome-wide-analyses-of-individual-strongyloides-stercoralis-nematoda-rhabditoidea-provide-insights-into-population-structure-and-reproductive-life-cycles
#18
Taisei Kikuchi, Akina Hino, Teruhisa Tanaka, Myo Pa Pa Thet Hnin Htwe Aung, Tanzila Afrin, Eiji Nagayasu, Ryusei Tanaka, Miwa Higashiarakawa, Kyu Kyu Win, Tetsuo Hirata, Wah Win Htike, Jiro Fujita, Haruhiko Maruyama
The helminth Strongyloides stercoralis, which is transmitted through soil, infects 30-100 million people worldwide. S. stercoralis reproduces sexually outside the host as well as asexually within the host, which causes a life-long infection. To understand the population structure and transmission patterns of this parasite, we re-sequenced the genomes of 33 individual S. stercoralis nematodes collected in Myanmar (prevalent region) and Japan (non-prevalent region). We utilised a method combining whole genome amplification and next-generation sequencing techniques to detect 298,202 variant positions (0...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28024666/strongyloides-stercoralis-infection-with-a-diffuse-miliary-pattern
#19
Bruno Hochhegger, Gláucia Zanetti, Edson Marchiori
No abstract text is available yet for this article.
December 23, 2016: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28007484/diagnosis-of-intestinal-parasites-in-a-rural-community-of-venezuela-advantages-and-disadvantages-of-using-microscopy-or-rt-pcr
#20
Renzo Nino Incani, Elizabeth Ferrer, Denise Hoek, Robbert Ramak, Jeroen Roelfsema, Lapo Mughini-Gras, Titia Kortbeek, Elena Pinelli
A cross-sectional study was carried out to determine the prevalence and diagnostic performance of microscopy and real time PCR (RT-PCR) for 14 intestinal parasites in a Venezuelan rural community with a long history of persistent intestinal parasitic infections despite the implementation of regular anthelminthic treatments. A total of 228 participants were included in this study. A multiplex RT-PCR was used for the detection of Dientamoeba fragilis, Giardia intestinalis, Cryptosporidium sp. and a monoplex RT-PCR for Entamoeba histolytica...
March 2017: Acta Tropica
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