Anja Holz, Nadia Obi, Wolfgang Ahrens, Klaus Berger, Barbara Bohn, Hermann Brenner, Beate Fischer, Julia Fricke, Amand Führer, Sylvia Gastell, Karin Halina Greiser, Volker Harth, Jana-Kristin Heise, Bernd Holleczek, Thomas Keil, Carolina J Klett-Tammen, Michael Leitzmann, Wolfgang Lieb, Claudia Meinke-Franze, Karin B Michels, Rafael Mikolajczyk, Katharina Nimptsch, Annette Peters, Tobias Pischon, Oliver Riedel, Tamara Schikowski, Sabine Schipf, Börge Schmidt, Matthias B Schulze, Andreas Stang, Kerstin Hellwig, Karin Riemann-Lorenz, Christoph Heesen, Heiko Becher
BACKGROUND: Multiple Sclerosis (MS) represents the most common inflammatory neurological disease causing disability in early adulthood. Childhood and adolescence factors might be of relevance in the development of MS. We aimed to investigate the association between various factors (e.g., prematurity, breastfeeding, daycare attendance, weight history) and MS risk. METHODS: Data from the baseline assessment of the German National Cohort (NAKO) were used to calculate adjusted hazard ratios (HR) and 95% confidence intervals (CI) for the association between childhood and adolescence factors and risk of MS...
April 13, 2024: BMC Neurology