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https://www.readbyqxmd.com/read/28432958/membrane-fusion-between-baculovirus-budded-virus-enveloped-particles-and-giant-liposomes-generated-using-a-droplet-transfer-method-for-the-incorporation-of-recombinant-membrane-proteins
#1
Misako Nishigami, Takaaki Mori, Masahiro Tomita, Kingo Takiguchi, Kanta Tsumoto
Giant proteoliposomes are generally useful as artificial cell membranes in biochemical and biophysical studies, and various procedures for their preparation have been reported. We present here a novel preparation technique that involves the combination of i) cell-sized lipid vesicles (giant unilamellar vesicles, GUVs) that are generated using the droplet-transfer method, where lipid monolayer-coated water-in-oil microemulsion droplets interact with oil/water interfaces to form enclosed bilayer vesicles, and ii) budded viruses (BVs) of baculovirus (Autographa californica nucleopolyhedrovirus) that express recombinant transmembrane proteins on their envelopes...
April 13, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28432888/removal-of-arsenate-and-dichromate-ions-from-different-aqueous-media-by-amine-based-p-taea-co-gde-microgels
#2
Saif Ur Rehman, Abdur Rahman Khan, Mehtap Sahiner, Sultan B Sengel, Nahit Aktas, Muhammad Siddiq, Nurettin Sahiner
In this work, microgels based on tris(2-aminoethyl) amine (TAEA) and glycerol diglycidyl ether (GDE) via simple microemulsion polymerization was prepared as p(TAEA-co-GDE) microgels were used as adsorbent for removal of dichromate (Cr (VI)) and arsenate (As (V)) ions from different aqueous environments. The p(TAEA-co-GDE) microgels were demonstrated very efficient adsorption capacity for Cr (VI), and As (V) that are 164.98 mg/g, and 123.64 mg/g from distilled (DI) water, respectively. The effect of the medium pH on the adsorption capacity of p(TAEA-co-GDE) microgels for Cr (VI) and As (V) ions were investigated...
April 19, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28420311/exploring-the-effect-of-formulation-parameters-on-the-particle-size-of-carboxymethyl-chitosan-nanoparticles-prepared-via-reverse-micellar-crosslinking
#3
Zeinab Sadat Sheikholeslami, Hamed Salimi-Kenari, Mohammad Imani, Mohammad Atai, Azizollah Nodehi
Carboxymethyl chitosan (CMCh), as a non-toxic, biocompatible and biodegradable semi-synthetic biopolymer with mucoadhesive properties is widely investigated for targeting drug or gene delivery applications. Here, fabrication of CMCh nanoparticles will be reported using a reverse (w/o) micellar system to provide particles with tunable mean sizes. Reverse microemulsions was prepared by dispersing aqueous solution of CMCh in n-hexane using sodium-bis(ethylhexyl)-sulfosuccinate (AOT) and glutaraldehyde (GA) as an emulsifier and a crosslinking agent, respectively...
April 19, 2017: Journal of Microencapsulation
https://www.readbyqxmd.com/read/28420288/microemulsion-loaded-hydrogel-as-a-promising-vehicle-for-dermal-delivery-of-the-antifungal-sertaconazole-design-optimization-and-ex-vivo-evaluation
#4
Shaimaa Ali Ali Radwan, Aliaa Nabil ElMeshad, Raguia Aly Shoukri
The purpose of the present study was to develop and optimize sertaconazole microemulsion-loaded hydrogel (STZ ME G) to enhance the dermal delivery and skin retention of the drug. Following screening of various oils for maximum drug solubility, twelve pseudoternary phase diagrams were constructed using oils (Peceol®, Capryol(®) 90), surfactants (Tween(®) 80, Cremophor(®) EL), a cosurfactant (Transcutol(®) P) and water. A 2(1)x 3(1)x 2(1)x 3(1) full factorial design was employed to optimize a ME of desirable characteristics...
April 19, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28415543/facile-synthesis-of-a-silver-nanoparticles-polypyrrole-nanocomposite-for-non-enzymatic-glucose-determination
#5
Maurício A Poletti Papi, Fabio R Caetano, Márcio F Bergamini, Luiz H Marcolino-Junior
The present work describes the synthesis of a new conductive nanocomposite based on polypyrrole (PPy) and silver nanoparticles (PPy-AgNP) based on a facile reverse microemulsion method and its application as a non-enzymatic electrochemical sensor for glucose detection. Focusing on the best sensor performance, all experimental parameters used in the synthesis of nanocomposite were optimized based on its electrochemical response for glucose. Characterization of the optimized material by FT-IR, cyclic voltammetry, and DRX measurements and TEM images showed good monodispersion of semispherical Ag nanoparticles capped by PPy structure, with size average of 12±5nm...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28415411/quality-by-design-approach-for-an-in-situ-gelling-microemulsion-of-lorazepam-via-intranasal-route
#6
Vidhi Shah, Mukesh Sharma, Radhika Pandya, Rajesh K Parikh, Bhavesh Bharatiya, Atindra Shukla, Hsieh-Chih Tsai
The present study illustrates the application of the concept of Quality by Design for development, optimization and evaluation of Lorazepam loaded microemulsion containing ion responsive In situ gelator gellan gum and carbopol 934. A novel approach involving interactions between surfactant and polymer was employed to achieve controlled drug release and reduced mucociliary clearance. Microemulsion formulated using preliminary solubility study and pseudo ternary phase diagrams showed significantly improved solubilization capacity of Lorazepam with 54...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28414245/interfacial-properties-and-monolayer-collapse-of-alkyl-benzene-sulfonate-surfactant-monolayers-at-the-decane-water-interface-from-molecular-dynamics-simulations
#7
Jacqueline S J Tan, Liping Zhang, Freda C H Lim, Daniel Wee Loong Cheong
The molecular structure of a surfactant molecule is known to have a great effect on the interfacial properties and the type of nanostructures formed. In this work, we have performed molecular dynamics simulations on six isomers of an alkyl benzene sulfonate surfactant to investigate the effect of the degree and position of aromatic substitution on the interfacial properties and on the collapse of the surfactant monolayer at a decane-water interface. The surface pressure of the monolayers were shown to increase with increasing surface coverage, until some of the monolayers become mechanically unstable and form large undulations...
April 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28411538/formulation-of-crude-oil-spill-dispersants-based-on-the-hld-concept-and-using-a-lipopeptide-biosurfactant
#8
Witchaya Rongsayamanont, Suwat Soonglerdsongpha, Nichakorn Khondee, Onruthai Pinyakong, Chantra Tongcumpou, David A Sabatini, Ekawan Luepromchai
Solvent-free dispersants for crude oil spills were formulated based on the hydrophilic-lipophilic deviation (HLD) concept and using lipopeptides from Bacillus sp. GY19. The lipopeptides were recovered and concentrated from cell-free broth by foam fractionation and freeze-drying. They had good surface activity under varying temperatures, pH and NaCl levels. Moreover, the lipopeptides had low toxicity to copepods (LC50 1174mg/L) and whiteleg shrimp (LC50 1050mg/L). The characteristic curvature (Cc) of the lipopeptides showed that they were more hydrophobic (Cc 4...
April 4, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28411057/microwave-assisted-microemulsion-technique-for-production-of-miconazole-nitrate-and-econazole-nitrate-loaded-solid-lipid-nanoparticles
#9
Rohan M Shah, Daniel S Eldridge, Enzo A Palombo, Ian H Harding
The microwave-assisted production of solid lipid nanoparticles (SLNs) is a novel technique reported recently by our group. The small particle size, solid nature and use of physiologically well-tolerated lipid materials make SLNs an interesting and potentially efficacious drug carrier. The main purpose of this research work was to investigate the suitability of microwave-assisted microemulsion technique to encapsulate selected ionic drug substances such as miconazole nitrate and econazole nitrate. The microwave-produced SLNs had a small size (250-300 nm), low polydispersity (<0...
April 11, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28403666/enhanced-acyclovir-delivery-using-w-o-type-microemulsion-preclinical-assessment-of-antiviral-activity-using-murine-model-of-zosteriform-cutaneous-hsv-1-infection
#10
Amanpreet Kaur, Gajanand Sharma, Vishal Gupta, Radha Kanta Ratho, Om Prakash Katare
The present study was aimed to develop and evaluate a microemulsion-based dermal drug delivery of an antiviral agent, acyclovir. A water-in-oil microemulsion was prepared using isopropyl myristate, Tween 20, Span 20, water and dimethylsulphoxide. It was characterized for drug content, stability, globule size, pH, viscosity and ex vivo permeation through mice skin. In vivo antiviral efficacy of optimized formulation was assessed in female Balb/c mice against herpes simplex virus-I (HSV-I)-induced infection. It was observed that optimized formulation when applied 24-h post-infection could completely inhibit the development of cutaneous herpetic lesions vis-à-vis marketed cream...
April 12, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28398647/synthesis-characterization-and-electrophoretic-concentration-of-titanium-dioxide-nanoparticles-in-aot-microemulsions
#11
Alexander I Bulavchenko, Nikita O Shaparenko, Marina G Demidova
Stable organosols of TiO2 nanoparticles were prepared by hydrolysis of titanium tetraisopropoxide (TTIP) in microemulsions of sodium bis(2-ethylhexyl)sulfoxynate (АОТ) in n-decane with increasing the content of aqueous pseudophase from 0.15 to 0.85 vol.%. As the water content increased, the hydrodynamic diameter of nanoparticles grew from 10 to 225 nm, and the  ζ-potential, from -6 to 18 mV (the surface of TiO2 nanoparticles was recharged when the water content was 0.45 vol.%). Nonaqueous electrophoresis in a capacitor-type cell made it possible to concentrate nanoparticles with a diameter of 60 to 225 nm (concentration factor was 10), separate 20 nm and 225 nm particles, and decrease the content of АОТ in organosol by an order of magnitude...
April 11, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28397267/stability-assessment-of-lycopene-microemulsion-prepared-using-tomato-industrial-waste-against-various-processing-conditions
#12
Atefeh Amiri-Rigi, Soleiman Abbasi
BACKGROUND: Green separation techniques are growing at a greater rate than solvent extraction owing to the constant consumer drive to "go natural". Considering the increasing evidences of the health benefits of lycopene and massive tomato industrial waste, in the present study, using microemulsion technique the lycopene was extracted from tomato industrial waste and its mean droplet size and size distribution was determined. Moreover, the effects of pasteurization, sterilization, freeze-thaw cycles and UV irradiation on the thermodynamic stability, turbidity and lycopene concentration of the lycopene microemulsion were monitored...
April 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28393764/highly-luminescent-silica-coated-cds-cdse-cds-nanoparticles-with-strong-chemical-robustness-and-excellent-thermal-stability
#13
Nianfang Wang, Sungjun Koh, Byeong Guk Jeong, Dongkyu Lee, Whi Dong Kim, Kyoungwon Park, Min Ki Nam, Kangha Lee, Yewon Kim, Baek-Hee Lee, Kangtaek Lee, Wan Ki Bae, Doh C Lee
We present facile synthesis of bright CdS/CdSe/CdS@SiO2 nanoparticles with 72% of quantum yields (QYs) retaining ca 80% of the original QYs. The main innovative point is the utilization of the highly luminescent CdS/CdSe/CdS seed/spherical quantum well/shell (SQW) as silica coating seeds. The significance of inorganic semiconductor shell passivation and structure design of quantum dots (QDs) for obtaining bright QD@SiO2 is demonstrated by applying silica encapsulation via reverse microemulsion method to three kinds of QDs with different structure: CdSe core and 2 nm CdS shell (CdSe/CdS-thin); CdSe core and 6 nm CdS shell (CdSe/CdS-thick); and CdS core, CdSe intermediate shell and 5 nm CdS outer shell (CdS/CdSe/CdS-SQW)...
May 5, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28391836/fluorescence-growth-of-self-polymerized-fluorescence-polydopamine-for-ratiometric-visual-detection-of-da
#14
Miao Yu, Yang Lu, Zhenjiang Tan
In this work, a novel and facile ratiometric fluorescence probe was prepared for the visual detection of dopamine (DA). In this detection system, red-emission CdTe@SiO2 (r-QDs@SiO2) was used as steady core of the probe and inverse microemulsion method was applied to synthesize uniform r-QDs@SiO2, this step could protect CdTe from contacting with human skin directly. Polydopamine (PDA) acted as response signal to detect DA, a very handy method which just combined polyethyleneimine (PEI) with DA together to synthesize PDA, this way for synthesis of PDA was much time-saving and non-toxic than any other methods...
June 1, 2017: Talanta
https://www.readbyqxmd.com/read/28390669/analysis-of-phenolic-acids-by-ionic-liquid-in-water-microemulsion-liquid-chromatography-coupled-with-ultraviolet-and-electrochemical-detector
#15
Li-Qing Peng, Jun Cao, Li-Jing Du, Qi-Dong Zhang, Yu-Tin Shi, Jing-Jing Xu
An environmentally friendly ionic liquid-in-water (IL/W) microemulsion was established and applied as mobile phase in microemulsion liquid chromatography (MELC) with ultraviolet (UV) detection or electrochemical detector (ECD) for analysis of phenolic compounds in real samples. The optimal condition of the method was using the best composition of microemulsion (0.2% w/v [HMIM]PF6, 1.0% w/v SDS, 3.0% w/v n-butanol, 95.8% v/v water, pH 2.5) with UV detection. The validation results indicated that the method provided high degree of sensitivity, precision and accuracy with the low limit of detections ranged from 17...
April 1, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28390344/interface-formation-during-silica-encapsulation-of-colloidal-cdse-cds-quantum-dots-observed-by-in-situ-raman-spectroscopy
#16
Amelie Biermann, Tangi Aubert, Philipp Baumeister, Emile Drijvers, Zeger Hens, Janina Maultzsch
We investigate the encapsulation of CdSe/CdS quantum dots (QDs) in a silica shell by in situ Raman spectroscopy and find a distinct shift of the CdS Raman signal during the first hours of the synthesis. This shift does not depend on the final silica shell thickness but on the properties of the initial core-shell QD. We find a correlation between the Raman shift rate and the speed of the silica formation and attribute this to the changing configuration of the outermost layers of the QD shell, where an interface to the newly formed silica is created...
April 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28388160/modeling-micelle-formation-and-interfacial-properties-with-isaft-classical-density-functional-theory
#17
Le Wang, Amin Haghmoradi, Jinlu Liu, Shun Xi, George J Hirasaki, Clarence A Miller, Walter G Chapman
Surfactants reduce the interfacial tension between phases, making them an important additive in a number of industrial and commercial applications from enhanced oil recovery to personal care products (e.g., shampoo and detergents). To help obtain a better understanding of the dependence of surfactantproperties on molecular structure, a classical density functional theory, also known as interfacial statistical associating fluid theory, has been applied to study the effects of surfactant architecture on micelle formation and interfacial properties for model nonionic surfactant/water/oil systems...
March 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28384538/study-on-the-applicability-of-dynamic-light-scattering-dls-to-microemulsions-including-supercritical-carbon-dioxide-swollen-micelles
#18
Shane Patrick Cadogan, Christian Joachim Hahn, Michael Heinrich Rausch, Andreas Paul Fröba
The applicability of dynamic light scattering (DLS) for the characterization of the size of supercritical carbon dioxide (sc-CO2)-swollen micelles in a polyester polyol-based multicomponent microemulsion with nonionic surfactant has been thoroughly proved for the first time in this work. Systematic experiments confirming that a hydrodynamic mode is observable in either a homodyne or a heterodyne detection scheme as well as the evaluation of the influence of the laser power applied to the slightly colored microemulsion have ensured an accurate implementation of this technique for a technically relevant system...
March 30, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28378606/efficacy-of-nano-and-microemulsion-based-topical-gels-in-delivery-of-ibuprofen-an-in-vivo-study
#19
Mosayeb Azizi, Fariba Esmaeili, Ali Reza Partoazar, Shahram Ejtemaei Mehr, Amir Amani
AIM: Nanoemulsion have shown many advantages in drug delivery systems. In this study, for the first time, analgesic and anti-inflammatory properties of a nanomelusion of almond oil with and without ibuprofen was compared with corresponding microemulsion and commercial topical gel of the drug using formalin and carrageenan tests, respectively. METHOD: Almond oil (oil phase) was mixed with Tween 80 and Span 80 (surfactants), and ethanol (co-surfactant) and them distilled water (aqueous phase) was then added to the mixture at once...
April 5, 2017: Journal of Microencapsulation
https://www.readbyqxmd.com/read/28378308/current-advancements-of-magnetic-nanoparticles-in-adsorption-and-degradation-of-organic-pollutants
#20
Mazhar Ul-Islam, Muhammad Wajid Ullah, Shaukat Khan, Shehrish Manan, Waleed Ahmad Khattak, Wasi Ahmad, Nasrullah Shah, Joong Kon Park
Nanotechnology is a fast-emerging field and has received applications in almost every field of life. Exploration of new synthetic technologies for size and shape control of nanomaterials is getting immense consideration owing to their exceptional properties and applications. Magnetic nanoparticles (MNPs) are among the most important group of nanoparticles thanks to their diverse applications in medical, electronic, environmental, and industrial sectors. There have been numerous synthetic routes of MNPs including thermal decomposition, co-precipitation, microemulsion, microwave assisted, chemical vapor deposition, combustion synthesis, and laser pyrolysis synthesis...
April 4, 2017: Environmental Science and Pollution Research International
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