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https://www.readbyqxmd.com/read/29245173/patient-perception-of-disease-related-symptoms-and-complications-in-relapsing-polychondritis
#1
Marcela A Ferrada, Peter C Grayson, Shubhasree Banerjee, Keith Sikora, Robert Colbert, Ninet Sinaii, James D Katz
OBJECTIVE: To assess patient-reported symptoms and burden of disease in relapsing polychondritis (RP). METHODS: Patients with RP completed a disease-specific online survey to identify symptoms attributed to illness. Patients were divided into subgroups based upon presence or absence of ear/nose, airway, or joint involvement. Pathway to diagnosis, treatment, and disease-related complications were assessed within each subgroup. RESULTS: Data from 304 respondents were included in this analysis...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245125/delayed-type-hypersensitivity-to-metals-in-connective-tissue-diseases-and-fibromyalgia
#2
REVIEW
Geir Bjørklund, Maryam Dadar, Jan Aaseth
Rheumatic diseases include a group of autoimmune disorders with environmental and genetic etiology that are characterized as a subgroup of connective tissue diseases (CTD). Rheumatoid arthritis (RA) often involves the small joints of the hands in a symmetrical fashion that can lead to loss of joint function, and RA, as well as Sjögren's syndrome (SS) and other rheumatic diseases, are often accompanied by sensitivity to metals. Numerous investigations on metal sensitivity were evaluated in this review. A detailed metal exposure history was collected by different evaluation of studies...
December 12, 2017: Environmental Research
https://www.readbyqxmd.com/read/29235496/involvement-of-trpm2-and-trpv1-channels-on-hyperalgesia-apoptosis-and-oxidative-stress-in-rat-fibromyalgia-model-protective-role-of-selenium
#3
Esra Yüksel, Mustafa Nazıroğlu, Mehmet Şahin, Bilal Çiğ
Fibromyalgia (FM) results in pain characterized by low selenium (Se) levels, excessive Ca2+ influx, reactive oxygen species (ROS) production, and acidic pH. TRPM2 and TRPV1 are activated by ROS and acid; nevertheless, their roles have not been elucidated in FM. Therefore, we investigated the contribution of TRPM2 and TRPV1 to pain, oxidative stress, and apoptosis in a rat model of FM and the therapeutic potential of Se. Thirty-six rats were divided into four groups: control, Se, FM, and FM + Se. The Se treatment reduced the FM-induced increase in TRPM2 and TRPV1 currents, pain intensity, intracellular free Ca2+, ROS, and mitochondrial membrane depolarization in the sciatic (SciN) and dorsal root ganglion (DRGN) neurons...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29232329/cortisol-and-subjective-stress-responses-to-acute-psychosocial-stress-in-fibromyalgia-patients-and-control-participants
#4
Eline Coppens, Stefan Kempke, Peter Van Wambeke, Stephan Claes, Bart Morlion, Patrick Luyten, Lukas Van Oudenhove
OBJECTIVE: Hypothalamic-pituitary-adrenal (HPA) axis dysfunction may play a role in fibromyalgia (FM) pathogenesis, but remains understudied in this disorder. Furthermore, early childhood adversities (ECA) are common in FM, but whether they moderate stress reactivity is unknown. Hence, we investigated cortisol and subjective responses to acute psychosocial stress in FM and controls, while adjusting for ECA. METHODS: Twenty-seven female FM patients and 24 age-matched female controls were recruited in a tertiary care center and through advertisements, respectively...
December 11, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29223727/urodynamic-characteristics-might-be-variable-in-bladder-pain-syndrome-interstitial-cystitis-patients-with-different-non-bladder-co-morbid-conditions
#5
Wei-Ming Cheng, Yu-Hua Fan, Alex T L Lin
BACKGROUND: The aim of the study was to identify the impact of non-bladder co-morbid conditions on the urodynamic characteristics of patients with bladder pain syndrome/interstitial cystitis. METHODS: Patients with bladder pain syndrome/interstitial cystitis completed the screening questionnaires for chronic fatigue syndrome, irritable bowel syndrome, fibromyalgia, temporo-mandibular disorders, multiple chemical sensitivities, tension/migraine headache, and localized myofascial pain disorder...
December 6, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29222936/role-of-central-oxytocin-and-dopamine-systems-in-nociception-and-their-possible-interactions-suggested-hypotheses
#6
Mohammed Gamal-Eltrabily, Alfredo Manzano-García
Central oxytocin and dopamine have an important role in the process of nociception at the spinal level as well as supraspinal structures, e.g. anterior cingulate cortex, insular cortex, amygdala, nucleus accumbens, and hypothalamus. Many studies have pointed out the importance of both systems in the pain descending modulatory system and in pain-related symptoms in some chronic disorders, e.g. Parkinson disease and fibromyalgia. The interaction between oxytocin and dopamine systems has been addressed in some motivational behaviors, e...
December 9, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/29220534/effects-of-acupuncture-treatment-on-fibromyalgia-symptoms-serotonin-and-substance-p-levels-a-randomized-sham-and-placebo-controlled-clinical-trial
#7
Saliha Karatay, Sibel Caglar Okur, Hulya Uzkeser, Kadir Yildirim, Fatih Akcay
Objective: The aim of this study was to evaluate the effects of acupuncture treatment on serum levels of serotonin and substance P (SP) as well as on clinical parameters in patients with fibromyalgia (FM). Methods: This is a randomized controlled clinical trial. Seventy-five women with FM were randomized into one of three kinds of acupuncture treatment: real acupuncture group (AcG), sham acupuncture group (ShG), and simulated acupuncture group (SiG). Treatments were applied semiweekly for four weeks...
December 6, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29214470/clinical-and-anti-aging-effect-of-mud-bathing-therapy-for-patients-with-fibromyalgia
#8
Toyoki Maeda, Yoshihiro Kudo, Takahiko Horiuchi, Naoki Makino
Spa bathing is known as a medical treatment for certain diseases causing chronic pains. Spa water contains mineral components which lower the specific heat of the water, resulting in a higher efficiency to warm body-core temperature. This phenomenon yields pain-relieving effect for rheumatoid arthritis, low back pain, sciatic neuralgia, fibromyalgia, etc. Here we introduce medical and biological effects of mud-spa-bathing therapy for fibromyalgia other than pain relief, the changes of blood examination data, and the telomere length of circulating leukocytes...
December 6, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/29210612/association-of-fine-motor-loss-and-allodynia-in-fibromyalgia-an-fnirs-study
#9
Aykut Eken, Didem Gökçay, Cemre Yılmaz, Bora Baskak, Ayşegül Baltacı, Murat Kara
Recent studies showed that fine motor control dysfunction was observed in fibromyalgia (FM) syndrome as well as allodynia. However, brain signatures of this association still remain unclear. In this study, finger tapping task (FTT) and median nerve stimulation (MNS) were applied to both hands of 15 FM patients and healthy controls (HC) to understand this relationship. Hemodynamic activity was measured simultaneously using functional near-infrared spectroscopy (fNIRS). Experiments were analyzed separately by using 2x2 repeated measures ANOVA...
December 6, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/29209204/reward-circuitry-plasticity-in-pain-perception-and-modulation
#10
REVIEW
Marcos F DosSantos, Brenda de Souza Moura, Alexandre F DaSilva
Although pain is a widely known phenomenon and an important clinical symptom that occurs in numerous diseases, its mechanisms are still barely understood. Owing to the scarce information concerning its pathophysiology, particularly what is involved in the transition from an acute state to a chronic condition, pain treatment is frequently unsatisfactory, therefore contributing to the amplification of the chronic pain burden. In fact, pain is an extremely complex experience that demands the recruitment of an intricate set of central nervous system components...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29204760/the-detection-of-arthritis-in-inflammatory-bowel-diseases-detail-questionnaire-development-and-preliminary-testing-of-a-new-tool-to-screen-patients-with-inflammatory-bowel-disease-for-the-presence-of-spondyloarthritis
#11
Marco Di Carlo, Michele Maria Luchetti, Devis Benfaremo, Eleonora Di Donato, Piergiorgio Mosca, Stefania Maltoni, Antonio Benedetti, Armando Gabrielli, Walter Grassi, Fausto Salaffi
To develop and to test in a preliminary way a new self-administered screening tool, called DETection of Arthritis in Inflammatory boweL diseases (DETAIL) questionnaire, in patients suffering from inflammatory bowel disease (IBD) not previously diagnosed as having a spondyloarthritis (SpA). DETAIL questionnaire was realized through the interrogation of 95 experts. They were asked to rate the importance of a list of items, derived from a review of the referral models of SpA, to detect the SpA manifestations in IBD patients...
December 4, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29199761/difference-in-regional-brain-volume-between-fibromyalgia-patients-and-long-term-meditators
#12
Nicolás Fayed, Gracián García-Martí, Roberto Sanz-Requena, Luis Marti-Bonmatí, Javier Garcia-Campayo
BACKGROUND: The practice of meditation has been shown to improve pain-related quality of life and also to alter brain activity. To assess brain volumetry in fibromyalgia (FM) patients, healthy meditators and healthy non-meditator control groups, and to elucidate the possible association between brain changes in meditators and years of meditation practice. METHODS: Twelve patients diagnosed with FM, eleven long-term Zen meditators and ten healthy control subjects closely matched for sex and age were recruited...
November 2017: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/29197121/the-clinical-anatomy-of-fibromyalgia
#13
REVIEW
Shehzad Khalid, Emily Simonds, Marios Loukas, R Shane Tubbs
INTRODUCTION: Fibromyalgia is a disorder characterized by pain and a spectrum of psychological comorbidities, rendering treatment difficult and often a financial burden. Findings regarding diagnosis, prevalence, comorbidities, and potential pathophysiological links are discussed herein. Fibromyalgia is a complex disorder and there are specific criteria that patients must meet for diagnosis, including scores on fibromyalgia questionnaires, commonalities of age, gender, menopause status, sleep disturbances, and mood symptoms...
December 2, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/29185967/increased-aortic-stiffness-in-patients-with-fibromyalgia-results-of-a-prospective-study-on-carotid-femoral-pulse-wave-velocity
#14
Konstantinos Triantafyllias, Marco Stortz, Michele de Blasi, Christian Leistner, Julia Weinmann-Menke, Andreas Schwarting
No abstract text is available yet for this article.
November 20, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29185675/muscle-stretching-exercises-and-resistance-training-in-fibromyalgia-which-is-better-a-three-arm-randomized-controlled-trial
#15
Ana Assumpção, Luciana A Matsutani, Susan L Yuan, Adriana S Santo, Juliana Sauer, Pamela Mango, Amelia P Marques
BACKGROUND: Exercise therapy is an effective component of fibromyalgia (FM) treatment. However, it is important to know the effects and specificities of the different types of exercise: muscle stretching and resistance training. AIM: To verify and compare the effectiveness of muscle stretching exercise and resistance training for symptoms and quality of life in FM patients. DESIGN: Randomized controlled trial. SETTING: Physical therapy service, FM outpatient clinic...
November 29, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29185281/ankylosing-spondylitis-and-neck-pain-mri-evidence-for-joint-and-entheses-inflammation-at-the-craniocervial-junction
#16
Cheri Korb, Abid Awisat, Doron Rimar, Itzhak Rosner, Arsen Schpigelman, Daniela Militianu, Gleb Slobodin
BACKGROUND: Magnetic resonance imaging (MRI), which has recently become the leading imaging modality in the study of ankylosing spondylitis (AS), has not been evaluated in the assessment of disease-specific changes at the craniocervical junction (CCJ) in patients with AS. OBJECTIVES: To describe the spectrum of active inflammatory lesions at the CCJ using MRI in a cohort of patients with AS and neck pain. METHODS: The study included 18 patients with AS presenting with neck pain and a control group of 9 fibromyalgia patients matched for age and levels of neck pain...
November 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29183878/evaluation-of-the-impact-of-concomitant-fibromyalgia-on-tnf-alpha-blockers-effectiveness-in-axial-spondyloarthritis-results-of-a-prospective-multicentre-study
#17
Anna Moltó, Adrien Etcheto, Laure Gossec, Nadia Boudersa, Pascal Claudepierre, Nicolas Roux, Lucie Lemeunier, Antoine Martin, Lartitia Sparsa, Pascal Coquerelle, Martin Soubrier, Serge Perrot, Maxime Dougados
OBJECTIVE: To describe the prevalence of fibromyalgia (FM) in an axial spondyloarthritis (axSpA) population and to confirm that concomitant FM had a negative impact on tumour necrosis factor blockers' (TNFb) response. DESIGN: Prospective observational study with two visits 3 months apart. PATIENTS: Adult patients with AxSpa initiating a TNFb. STUDY GROUPS: FM was defined by the Fibromyalgia Rapid Screening Tool (FiRST) at baseline and also by a sustained positive FiRST (both visits) and by a fulfilment of the 1990 American College of Rheumatology criteria for FM...
November 28, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29178378/prevalence-of-arthritis-revisited
#18
EDITORIAL
Jeffrey N Katz
Estimates of disease prevalence have far-reaching consequences. By providing a baseline understanding of a disease's impact, these estimates are used to justify investment in research, prevention and treatment. For years, estimates of arthritis prevalence have been derived from a single screening question on the National Health Interview Survey (NHIS): "Have you ever been told by a doctor or other health professional that you have some form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia?" This question alone grounds the prevailing estimates of about 54 million US adults living with arthritis...
November 27, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29177458/a-survey-of-physicians-knowledge-and-adherence-to-the-diagnostic-criteria-for-fibromyalgia
#19
Dinesh Kumbhare, Sara Ahmed, Tori Sander, Liza Grosman-Rimon, John Srbely
Objective: In 2010, Wolfe et al. demonstrated poor physician use of the 1990 fibromyalgia diagnostic criteria and proposed the 2010 criteria to address physician shortcomings. No follow-up studies have investigated whether physicians are using these criteria. The purpose of this study was to provide seminal data on physician knowledge and use of the fibromyalgia diagnostic criteria. Methods: This was an observational study. A questionnaire was distributed to a convenience sample of physicians who diagnose chronic pain conditions...
November 21, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29172038/musculoskeletal-pain-and-musculoskeletal-syndromes-in-adolescents-are-related-to-electronic-devices
#20
Lígia Bruni Queiroz, Benito Lourenço, Luiz Eduardo Vargas Silva, Daniela Mencaroni Rodrigues Lourenço, Clovis Artur Silva
OBJECTIVE: To evaluate television and simultaneous electronic devices use in adolescents with musculoskeletal pain and musculoskeletal pain syndromes. METHODS: A cross-sectional study was performed in 299 healthy adolescents of a private school. All students completed a self-administered questionnaire, including: demographic data, physical activities, musculoskeletal pain symptoms, and use of simultaneous television/electronic devices (computer, internet, electronic games, and cell phones)...
November 21, 2017: Jornal de Pediatria
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