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https://www.readbyqxmd.com/read/29155041/epidemiological-and-clinical-characteristics-of-coronavirus-and-bocavirus-respiratory-infections-after-allogeneic-stem-cell-transplantation-a-prospective-single-center-study
#1
José Luis Piñana, Silvia Madrid, Ariadna Pérez, Juan Carlos Hernández-Boluda, Estela Giménez, María José Terol, Marisa Calabuig, David Navarro, Carlos Solano
Epidemiological data about coronaviruses (CoVs) and human bocavirus (HBoV) in the setting of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is scarce. METHODS: We conducted a prospective longitudinal study on respiratory viral infections (RVIs) in allo-HSCT recipients having respiratory symptoms from December 2013 until June 2016. Respiratory virus in upper and/or lower respiratory tract (URT and LRT) specimens were tested using Luminex xTAG RVP Fast v1 assay. RESULTS: Seventy-nine consecutive allo-HSCT recipients developed a total of 192 virologically documented RVI episodes over 30 months...
November 15, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29154408/chemokine-c-c-motif-ligand-25-expressed-by-trophoblast-cells-and-leukocytes-bearing-its-receptor-ccr9-an-alliance-during-embryo-implantation
#2
Rodrigo Barbano Weingrill, Mara S Hoshida, Ciro Dresch Martinhago, Simone Correa-Silva, Elaine Cardoso, Patrícia Palmeira, Claudio Romero Farias Marinho, Estela Bevilacqua
PROBLEM: We hypothesized that trophoblast expression of Ccl25 attracts a specific leukocyte cell population to the implantation site for local regulation. METHOD OF STUDY: Mice blastocysts, ectoplacental cones, and decidua at gestational days 3.5-7.5 were evaluated for Ccl25 and Ccr9 expressions. Peripheral availability and characterization of Ccr9+ leukocytes were determined by flow cytometry. Leukocyte chemotaxis was assessed in the presence of Ccl25 recombinant protein and embryos using antisense oligomers (ODNs) to Ccl25 and Ccr9 neutralizing antibody...
November 20, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29150103/body-composition-of-fanconi-anemia-patients-after-hematopoietic-stem-cell-transplantation
#3
Priscilla Peixoto Policarpo da Silva, Daniella Schmit, Carmem Bonfim, Denise Johnsson Campos, Estela Iraci Rabito, Regina Maria Vilela
INTRODUCTION: Fanconi anemia is a rare genetic disease linked to bone marrow failure; a possible treatment is hematopoietic stem cell transplantation. Changes in the nutritional status of Fanconi anemia patients are not very well known. This study aimed to characterize body composition of adult, children and adolescent patients with Fanconi anemia who were submitted to hematopoietic stem cell transplantation or not. METHODS: This cross-sectional study enrolled 63 patients (29 adults and 34 children and adolescents)...
October 2017: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/29149021/using-gamma-and-quantile-regressions-to-explore-the-association-between-job-strain-and-adiposity-in-the-elsa-brasil-study-does-gender-matter
#4
Maria de Jesus Mendes da Fonseca, Leidjaira Lopes Juvanhol, Lúcia Rotenberg, Aline Araújo Nobre, Rosane Härter Griep, Márcia Guimarães de Mello Alves, Letícia de Oliveira Cardoso, Luana Giatti, Maria Angélica Nunes, Estela M L Aquino, Dóra Chor
This paper explores the association between job strain and adiposity, using two statistical analysis approaches and considering the role of gender. The research evaluated 11,960 active baseline participants (2008-2010) in the ELSA-Brasil study. Job strain was evaluated through a demand-control questionnaire, while body mass index (BMI) and waist circumference (WC) were evaluated in continuous form. The associations were estimated using gamma regression models with an identity link function. Quantile regression models were also estimated from the final set of co-variables established by gamma regression...
November 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29145817/family-context-and-individual-situation-of-teens-before-during-and-after-pregnancy-in-mexico-city
#5
Reyna Sámano, Hugo Martínez-Rojano, David Robichaux, Ana Lilia Rodríguez-Ventura, Bernarda Sánchez-Jiménez, Maria de la Luz Hoyuela, Estela Godínez, Selene Segovia
BACKGROUND: In the last 20 years, adolescent pregnancy has become one of the most critical problems affecting women in Latin America and the Caribbean. METHODS: This qualitative study was based on in-depth interviews with 29 teen mothers. All of the pregnant teens were from low- to lower-middle-class social strata in the Mexico City metropolitan area. The family (living with the girl) and the individual context of pregnant teens were analysed on the basis of data from at least three interviews: during pregnancy and at approximately 6 and 24 months following delivery...
November 16, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29145474/long-3-utr-of-nurr1-mrnas-is-targeted-by-mirnas-in-mesencephalic-dopamine-neurons
#6
Luis Alberto Pereira, Roberto Munita, Marcela Paz González, María Estela Andrés
The development of mesencephalic dopamine neurons and their survival later in life requires the continuous presence of the transcription factor Nurr1 (NR4A2). Nurr1 belongs to the nuclear receptors superfamily. However, it is an orphan member that does not require a ligand to regulate the transcription of its target genes. Therefore, controlling the expression of Nurr1 is an important manner to control its function. Several reports have shown that microRNAs (miRNAs) regulate Nurr1 expression. However, Nurr1 has several splicing variants, posing the question what variants are subjected to miRNA regulation...
2017: PloS One
https://www.readbyqxmd.com/read/29138300/high-zika-virus-seroprevalence-in-salvador-northeastern-brazil-limits-the-potential-for-further-outbreaks
#7
Eduardo Martins Netto, Andres Moreira-Soto, Celia Pedroso, Christoph Höser, Sebastian Funk, Adam J Kucharski, Alexandra Rockstroh, Beate M Kümmerer, Gilmara Souza Sampaio, Estela Luz, Sara Nunes Vaz, Juarez Pereira Dias, Fernanda Anjos Bastos, Renata Cabral, Thomas Kistemann, Sebastian Ulbert, Xavier de Lamballerie, Thomas Jaenisch, Oliver J Brady, Christian Drosten, Manoel Sarno, Carlos Brites, Jan Felix Drexler
During 2015 to 2016, Brazil reported more Zika virus (ZIKV) cases than any other country, yet population exposure remains unknown. Serological studies of ZIKV are hampered by cross-reactive immune responses against heterologous viruses. We conducted serosurveys for ZIKV, dengue virus (DENV), and Chikungunya virus (CHIKV) in 633 individuals prospectively sampled during 2015 to 2016, including microcephaly and non-microcephaly pregnancies, HIV-infected patients, tuberculosis patients, and university staff in Salvador in northeastern Brazil using enzyme-linked immunosorbent assays (ELISAs) and plaque reduction neutralization tests...
November 14, 2017: MBio
https://www.readbyqxmd.com/read/29134938/short-term-incubation-of-positive-blood-cultures-in-brain-heart-infusion-broth-accelerates-identification-of-bacteria-by-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry
#8
Ignacio Torres, Estela Gimenez, Tania Pascual, Felipe Bueno, Dixie Huntley, Mireia Martínez, David Navarro
PURPOSE: Fast identification of bacteria directly from positive blood cultures (BCs) by matrix-assisted laser desorption/ionization time-of-flight mass-spectrometry (MALDI-TOF MS) can be achieved either using the MALDI Sepsityper kit (protein extraction method) or after a short-term pre-cultivation step on solid medium. We developed a new method that involves short-term enrichment of positive BCs in brain-heart infusion broth (BHI) prior to MALDI-TOF MS analysis. METHODOLOGY: Eighty-four BCs flagged as positive were included in this study; these were processed in parallel either directly using the MALDI Sepsityper kit or following a short-term culture either in BHI or on Columbia blood agar with 5 % sheep blood (CBA)...
November 14, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29127045/the-myogenic-regulatory-factors-determinants-of-muscle-development-cell-identity-and-regeneration
#9
REVIEW
J Manuel Hernández-Hernández, Estela G García-González, Caroline E Brun, Michael A Rudnicki
The Myogenic Regulatory Factors (MRFs) Myf5, MyoD, myogenin and MRF4 are members of the basic helix-loop-helix family of transcription factors that control the determination and differentiation of skeletal muscle cells during embryogenesis and postnatal myogenesis. The dynamics of their temporal and spatial expression as well as their biochemical properties have allowed the identification of a precise and hierarchical relationship between the four MRFs. This relationship establishes the myogenic lineage as well as the maintenance of the terminal myogenic phenotype...
November 7, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/29122230/cognitive-stimulation-of-elderly-residents-in-social-protection-centers-in-cartagena-2014
#10
Estela Melguizo Herrera, Anyel Bertel De La Hoz, Diego Paternina Osorio, Yurani Felfle Fuentes, Leidy Porto Osorio
OBJECTIVE: To determine the effectiveness of a program of cognitive stimulation of the elderly residents in Social Protection Centers in Cartagena, 2014. METHODS: Quasi-experimental study with pre and post tests in control and experimental groups. A sample of 37 elderly residents in Social Protection Centers participated: 23 in the experimental group and 14 in the control group. A survey and a mental evaluation test (Pfeiffer) were applied. The experimental group participated in 10 sessions of cognitive stimulation...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29121794/what-factors-explain-bicycling-and-walking-for-commuting-by-elsa-brasil-participants
#11
Sheila Maria Alvim de Matos, Francisco José Gondim Pitanga, Maria da Conceição C Almeida, Ciro Oliveira Queiroz, Clarice Alves Dos Santos, Rogerio Tosta de Almeida, Ianne Tayrine Martins da Silva, Rosane Harter Griep, Leila Denise Alves Ferreira Amorim, Ana Luísa Patrão, Estela M L Aquino
PURPOSE: To analyze the factors associated with commuting by bicycling and walking in adult participants from ELSA-Brasil (Longitudinal Study of Adult Health). DESIGN: Cross-sectional. SETTING: Six teaching/research institutions throughout Brazil. PARTICIPANTS: A total of 15 105 civil servants. MEASURES: Commuting by bicycling and walking was analyzed using the long-form International Physical Activity Questionnaire...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29115663/endogenous-annexin-a1-anxa1-modulates-early-phase-gestation-and-offspring-sex-ratio-skewing
#12
Cristina Bichels Hebeda, Isabel Daufenback Machado, Isadora Reif-Silva, Jusciele Brogin Moreli, Sonia Maria Oliani, Suchita Nadkarni, Mauro Perretti, Estela Bevilacqua, Sandra H P Farsky
Annexin A1 (AnxA1) is a glucocorticoid-regulated anti-inflammatory protein secreted by phagocytes and other specialised cells. In the endocrine system, AnxA1 controls secretion of steroid hormones and it is abundantly expressed in the testis, ovaries, placenta and seminal fluid, yet its potential modulation of fertility has not been described. Here we observed that AnxA1 knockout (KO) mice delivered a higher number of pups, with a higher percentage of female offsprings. This profile was not dependent on the male features, as sperm from KO male mice did not present functional alterations, and had an equal proportion of Y and X chromosomes, comparable to wild type (WT) male mice...
November 8, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29114855/panel%C3%A2-report-ipa-congress-buenos-aires-2017-intimacy-las-experiencias-traumaticas-no-representadas-unrepresented-traumatic-experiences
#13
Estela Rubinstein Gloger
No abstract text is available yet for this article.
November 8, 2017: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/29108028/decreased-plasma-concentrations-of-bdnf-and-igf-1-in-abstinent-patients-with-alcohol-use-disorders
#14
Nuria García-Marchena, Daniel Silva-Peña, Ana Isabel Martín-Velasco, María Ángeles Villanúa, Pedro Araos, María Pedraz, Rosa Maza-Quiroga, Pablo Romero-Sanchiz, Gabriel Rubio, Estela Castilla-Ortega, Juan Suárez, Fernando Rodríguez de Fonseca, Antonia Serrano, Francisco Javier Pavón
The identification of growth factors as potential biomarkers in alcohol addiction may help to understand underlying mechanisms associated with the pathogenesis of alcohol use disorders (AUDs). Previous studies have linked growth factors to neural plasticity in neurocognitive impairment and mental disorders. In order to further clarify the impact of chronic alcohol consumption on circulating growth factors, a cross-sectional study was performed in abstinent AUD patients (alcohol group, N = 91) and healthy control subjects (control group, N = 55) to examine plasma concentrations of brain-derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1) and IGF-1 binding protein-3 (IGFBP-3)...
2017: PloS One
https://www.readbyqxmd.com/read/29105360/pseudoprogression-as-an-adverse-event-of-glioblastoma-therapy
#15
Carmen Balaña, Jaume Capellades, Estela Pineda, Anna Estival, Josep Puig, Sira Domenech, Eugenia Verger, Teresa Pujol, Maria Martinez-García, Laura Oleaga, JoseMaria Velarde, Carlos Mesia, Rafael Fuentes, Jordi Marruecos, Sonia Del Barco, Salvador Villà, Cristina Carrato, Oscar Gallego, Miguel Gil-Gil, Jordi Craven-Bartle, Francesc Alameda
We explored predictive factors of pseudoprogression (PsP) and its impact on prognosis in a retrospective series of uniformly treated glioblastoma patients. Patients were classified as having PsP, early progression (eP) or neither (nP). We examined potential associations with clinical, molecular, and basal imaging characteristics and compared overall survival (OS), progression-free survival (PFS), post-progression survival (PPS) as well as the relationship between PFS and PPS in the three groups. Of the 256 patients studied, 56 (21...
November 3, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/29104876/psychopathological-symptoms-and-psychological-wellbeing-in-mexican-undergraduate-students
#16
Mariel Contreras, Ana Mariela de León, Estela Martínez, Elsa Melissa Peña, Luana Marques, Julia Gallegos
College life involves a process of adaptation to changes that have an impact on the psycho-emotional development of students. Successful adaptation to this stage involves the balance between managing personal resources and potential stressors that generate distress. This epidemiological descriptive and transversal study estimates the prevalence of psychopathological symptomatology and psychological well-being among 516 college students, 378 (73.26%) women and 138 (26.74%) men, ages between 17 and 24, from the city of Monterrey in Mexico...
June 2017: International Journal of Social Science Studies
https://www.readbyqxmd.com/read/29096390/epstein-barr-virus-dna-load-kinetics-analysis-in-allogeneic-hematopoietic-stem-cell-transplant-recipients-is-it-of-any-clinical-usefulness
#17
Carlos Solano, Eva María Mateo, Ariadna Pérez, Alberto Talaya, María José Terol, Eliseo Albert, Estela Giménez, Víctor Vinuesa, José Luis Piñana, Juan Carlos Hernández Boluda, David Navarro
BACKGROUND: There is a lack of clinical information regarding the usefulness of plasma Epstein-Barr virus (EBV) DNA load kinetics analyses in the management of EBV infections in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. Namely, it remains unknown whether this type of analysis can help physicians to anticipate the development of high-level EBV DNAemia episodes requiring rituximab treatment or predict the risk of recurrent EBV DNAemia or post-transplant lymphoproliferative disorders (PTLDs)...
October 27, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29084140/dna-damage-repair-system-in-plants-a-worldwide-research-update
#18
REVIEW
Estela Gimenez, Francisco Manzano-Agugliaro
Living organisms are usually exposed to various DNA damaging agents so the mechanisms to detect and repair diverse DNA lesions have developed in all organisms with the result of maintaining genome integrity. Defects in DNA repair machinery contribute to cancer, certain diseases, and aging. Therefore, conserving the genomic sequence in organisms is key for the perpetuation of life. The machinery of DNA damage repair (DDR) in prokaryotes and eukaryotes is similar. Plants also share mechanisms for DNA repair with animals, although they differ in other important details...
October 30, 2017: Genes
https://www.readbyqxmd.com/read/29077503/radiographic-assessment-of-lower-limb-discrepancy
#19
Maria Reina-Bueno, Guillermo Lafuente-Sotillos, Jose M Castillo-Lopez, Estela Gomez-Aguilar, Pedro V Munuera-Martinez
BACKGROUND: This study compares different lower-limb length measurements using tests of lower-limb upright full-length radiography and anteroposterior radiography of load-bearing hips. METHODS: Forty-seven consecutive individuals aged 17 to 61 years (mean ± SD, 31.47 ± 11.42 years) voluntarily took part in the study; 23 (48.9%) were women and 24 (51.1%) were men. All individuals presenting a difference of 5 mm or greater between both lower limbs quantified with a tape measure were included...
September 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/29069199/on-integrated-residency-in-health-with-emphasis-on-health-surveillance
#20
Andrei Fernandes da Rocha, Anelise Breier, Bianca de Souza, Camila Neves de Almeida, Caroline Mello Dos Santos, Claudia Cristina Rohloff, Estela Lopes Scariot, João Vinicius Ribeiro Azambuja, Joaquim Basso Cartana, Natalia Canal, Niura Massário Dos Santos, Simone Gonçalves Menegotto Reinher
Taking into account the four underpinning areas of Health Surveillance (environmental, epidemiological, health and worker's health), the performance of professionals in this area requires a broad and complex set of information from many fields of knowledge, including that which is not classified as health. Considering the need to prepare professionals to work in Health Surveillance in the Unified Health System (SUS), integrating the four fields of knowledge, the Public Health School of Rio Grande do Sul (ESP/RS) and the surveillance areas of the municipality of Porto Alegre and Rio Grande do Sul State have established a new emphasis in the traditional residency of ESP/RS...
October 2017: Ciência & Saúde Coletiva
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