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https://www.readbyqxmd.com/read/29433996/gelatin-thoracic-paravertebral-teaching-model-for-placement-of-a-continuous-infusion-catheter-in-the-extrathoracic-paravertebral-space
#1
Shruti Sevak, Ashley Woodfin, Zachary Hothem, Rose Callahan, James Robbins, Kathryn Ziegler
OBJECTIVE: Our aim was to develop an ultrasound-guided training curriculum for continuous infusion catheter placement in the paravertebral space and to create a gelatin thoracic spine-rib model for use in this training. We sought to create a model that was inexpensive and reusable such that multiple participants could use one model during training. DESIGN: The model was prepared by embedding a firm foam thoracic spine replica with bilateral attached ribs into an opaque gelatin mixture...
February 9, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29432343/clinical-impact-of-radioguided-localization-in-the-treatment-of-solitary-pulmonary-nodule-a-20-year-retrospective-analysis
#2
Gianpiero Manca, Federico Davini, Elisa Tardelli, Annalisa De Liperi, Fabio Falaschi, Franca Melfi, Patrick M Colletti, Domenico Rubello, Duccio Volterrani, Giuseppe Boni
PURPOSE: Incidental solitary pulmonary nodules (SPNs) have become an increasingly common CT finding worldwide. Although there are currently many imaging strategies for evaluating SPNs, the differential diagnosis and management of SPNs remains complex because of overlap between benign and malignant processes. Moreover, transbronchial or percutaneous CT-guided biopsies do not always allow definitive diagnoses. In such cases, video-assisted thoracic surgery (VATS) has become the preferred surgical procedure for diagnosis and, in selected cases, for treatment of indeterminate SPNs...
February 9, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29423312/epidemiological-profile-of-spinal-cord-injuries-at-a-tertiary-rehabilitation-center-in-kuwait
#3
L Prasad, S Al Kandari, U Ramachandran, D Shehab, S Alghunaim
Study design: Retrospective, descriptive study. Objective: To describe the epidemiological profile of patients with spinal cord injury (SCI) in Kuwait. Setting: Physical Medicine and Rehabilitation Hospital, Kuwait. Methods: Review of medical records of 241 adult patients with SCI admitted during the period 2010-2015. The data collected included gender, age, etiology, neurological and vertebral level of injury and American Spinal Injury Association impairment scale (AIS)...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29420109/vasodilation-and-antihypertensive-activities-of-swietenia-macrophylla-mahogany-seed-extract
#4
Yung Sing Ch'ng, Yean Chun Loh, Chu Shan Tan, Mariam Ahmad, Mohd Zaini Asmawi, Wan Maznah Wan Omar, Mun Fei Yam
The seeds of Swietenia macrophylla King (SM) (Meliaceae) are used as a folk medicine for the treatment of hypertension in Malaysia. However, the antihypertensive and vasorelaxant effects of SM seeds are still not widely studied. Thus, this study was designed to investigate the in vivo antihypertensive effects and in vitro mechanism of vasorelaxation of a 50% ethanolic SM seed extract (SM50) and the fingerprint of SM50 was developed through tri-step Fourier transform infrared (FTIR) spectroscopy. The vasorelaxant activity and the underlying mechanisms of SM50 were evaluated on thoracic aortic rings isolated from Sprague-Dawley rats in the presence of antagonists...
February 8, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29405770/liquid-biopsy-and-its-role-in-an-advanced-clinical-trial-for-lung-cancer
#5
Donald J Johann, Mathew Steliga, Ik J Shin, Donghoon Yoon, Konstantinos Arnaoutakis, Laura Hutchins, Meeiyueh Liu, Jason Liem, Karl Walker, Andy Pereira, Mary Yang, Susanne K Jeffus, Erich Peterson, Joshua Xu
Liquid biopsy methodologies, for the purpose of plasma genotyping of cell-free DNA (cfDNA) of solid tumors, are a new class of novel molecular assays. Such assays are rapidly entering the clinical sphere of research-based monitoring in translational oncology, especially for thoracic malignancies. Potential applications for these blood-based cfDNA assays include: (i) initial diagnosis, (ii) response to therapy and follow-up, (iii) tumor evolution, and (iv) minimal residual disease evaluation. Precision medicine will benefit from cutting-edge molecular diagnostics, especially regarding treatment decisions in the adjuvant setting, where avoiding over-treatment and unnecessary toxicity are paramount...
February 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29404162/the-view-of-the-turkish-thoracic-society-on-the-report-of-the-gold-2017-global-strategy-for-the-diagnosis-management-and-prevention-of-copd
#6
Nurdan Köktürk, Alev Gürgün, Elif Şen, Ali Kocabaş, Mehmet Polatlı, Sibel Atış Naycı, Lütfi Çöplü, Emel Tellioğlu, Funda Elmas, Ertürk Erdinç
Since the Global Initiative for Obstructive Lung Disease (GOLD) published its first guidelines on chronic obstructive pulmonary disease (COPD) in 2001, much has changed till 2017. Previous versions of GOLD guidelines mentioned the forced expiratory volume in one second (FEV1)-based approach for staging and treatment modalities. Since 2011, a composite multi-dimensional approach has been introduced to cover various aspects of the disease. Unfortunately, this approach was not found to be correlated with mortality as well as the FEV1-based approach, despite the fact that it was better for estimating exacerbation rates...
April 2017: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/29388824/research-priorities-in-pathophysiology-for-sleep-disordered-breathing-in-patients-with-chronic-obstructive-pulmonary-disease-an-official-american-thoracic-society-research-statement
#7
Atul Malhotra, Alan R Schwartz, Hartmut Schneider, Robert L Owens, Pamela DeYoung, MeiLan K Han, Jadwiga A Wedzicha, Nadia N Hansel, Michelle R Zeidler, Kevin C Wilson, M Safwan Badr
BACKGROUND: Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) are common conditions; the co-occurrence of these diseases, called the overlap syndrome (OVS), has been associated with poor health outcomes. PURPOSE: The purpose of this Official American Thoracic Society Research Statement is to describe pathophysiology, epidemiology, outcomes, diagnostic metrics, and treatment of OVS, as well as to identify important gaps in knowledge and make recommendations for future research...
February 1, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29388810/knowledge-gaps-in-the-perioperative-management-of-adults-with-obstructive-sleep-apnea-and-obesity-hypoventilation-syndrome-an-official-american-thoracic-society-workshop-report
#8
Najib T Ayas, Cheryl R Laratta, John M Coleman, Anthony G Doufas, Matthias Eikermann, Peter C Gay, Daniel J Gottlieb, Indira Gurubhagavatula, David R Hillman, Roop Kaw, Atul Malhotra, Babak Mokhlesi, Timothy I Morgenthaler, Sairam Parthasarathy, Satya Krishna Ramachandran, Kingman P Strohl, Patrick J Strollo, Michael J Twery, Phyllis C Zee, Frances F Chung
The purpose of this workshop was to identify knowledge gaps in the perioperative management of obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS). A single-day meeting was held at the American Thoracic Society Conference in May, 2016, with representation from many specialties, including anesthesiology, perioperative medicine, sleep, and respiratory medicine. Further research is urgently needed as we look to improve health outcomes for these patients and reduce health care costs. There is currently insufficient evidence to guide screening and optimization of OSA and OHS in the perioperative setting to achieve these objectives...
February 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29380427/real-time-correction-of-respiration-induced-distortions-in-the-human-spinal-cord-using-a-24-channel-shim-array
#9
Ryan Topfer, Alexandru Foias, Nikola Stikov, Julien Cohen-Adad
PURPOSE: To reduce respiration-induced magnetic field distortions and the attendant image artifacts in echo-planar imaging (EPI) of the human spinal cord. METHODS: Using a custom-designed 24-channel shim array, shim updates were issued in real time based on a concurrently monitored respiratory trace and a pair of gradient echo (GRE) field maps acquired during an initial training phase. Proof-of-concept application in GRE-EPI was conducted in 6 subjects. RESULTS: Over the thoracic spinal cord, real-time shimming reduced respiration-induced distortions in the EPI by 48...
January 29, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29368030/influence-of-family-on-expected-benefits-of-complementary-and-alternative-medicine-cam-in-cancer-patients
#10
Shelly Latte-Naor, Robert Sidlow, Lingyun Sun, Qing S Li, Jun J Mao
BACKGROUND: Cancer patients often use complementary and alternative medicine (CAM) based on recommendations from family. However, the relationship between family endorsement of CAM and the patient's expectation of its benefits has never been quantified. METHODS: Between 2010 and 2011, we conducted a cross-sectional survey study among patients with a diagnosis of cancer recruited from thoracic, breast, and gastrointestinal medical oncology clinics at a single academic cancer center...
January 24, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29362176/the-society-of-thoracic-surgeons-the-society-of-cardiovascular-anesthesiologists-and-the-american-society-of-extracorporeal-technology-clinical-practice-guidelines-anticoagulation-during-cardiopulmonary-bypass
#11
Linda Shore-Lesserson, Robert A Baker, Victor A Ferraris, Philip E Greilich, David Fitzgerald, Philip Roman, John W Hammon
Despite more than a half century of "safe" cardiopulmonary bypass (CPB), the evidence base surrounding the conduct of anticoagulation therapy for CPB has not been organized into a succinct guideline. For this and other reasons, there is enormous practice variability relating to the use and dosing of heparin, monitoring heparin anticoagulation, reversal of anticoagulation, and the use of alternative anticoagulants. To address this and other gaps, The Society of Thoracic Surgeons, the Society of Cardiovascular Anesthesiologists, and the American Society of Extracorporeal Technology developed an Evidence Based Workgroup...
February 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29352416/point-of-care-ultrasound-in-pediatric-anesthesiology-and-critical-care-medicine
#12
REVIEW
Erik Su, Nicholas Dalesio, Aliaksei Pustavoitau
Ultrasound has increasingly become a clinical asset in the hands of the anesthesiologist and intensivist who cares for children. Though many applications for ultrasound parallel adult modalities, children as always are not simply small adults and benefit from the application of ultrasound to their management in various ways. Body composition and size are important factors that affect ultrasound performance in the child, as are the pathologies that may uniquely afflict children and aspects of procedures unique to this patient population...
January 19, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29346209/the-society-of-thoracic-surgeons-the-society-of-cardiovascular-anesthesiologists-and-the-american-society-of-extracorporeal-technology-clinical-practice-guidelines-anticoagulation-during-cardiopulmonary-bypass
#13
Linda Shore-Lesserson, Robert A Baker, Victor A Ferraris, Philip E Greilich, David Fitzgerald, Philip Roman, John W Hammon
Despite more than a half century of "safe" cardiopulmonary bypass (CPB), the evidence base surrounding the conduct of anticoagulation therapy for CPB has not been organized into a succinct guideline. For this and other reasons, there is enormous practice variability relating to the use and dosing of heparin, monitoring heparin anticoagulation, reversal of anticoagulation, and the use of alternative anticoagulants. To address this and other gaps, The Society of Thoracic Surgeons, the Society of Cardiovascular Anesthesiologists, and the American Society of Extracorporeal Technology developed an Evidence Based Workgroup...
February 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29345550/an-anatomy-pre-course-predicts-student-performance-in-a-professional-veterinary-anatomy-curriculum
#14
Margaret A McNulty, Michelle D Lazarus
Little to no correlation has been identified between previous related undergraduate coursework or outcomes on standardized tests and performance in a veterinary curriculum, including anatomy coursework. Therefore, a relatively simplistic method to predict student performance before entrance would be advantageous to many. The purpose of this study was to evaluate whether there is a correlation between performance in a veterinary anatomy pre-course and subsequent performance within a professional anatomy curriculum...
January 18, 2018: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/29337450/-emergency-medicine-update-2017
#15
Frédéric Rouyer, Fabrice Dami, Olivier Grosgurin, Valériane Rossier, Majd Ramlawi, Mathieu Pasquier, Olivier T Rutschmann
Emergency medicine is part of the current stream of efficient and qualitative medicine : 1) the modified Valsava maneuver results in the resolution of almost 50% of supra-ventricular tachycardia without any drug; 2) lung echography performed by emergency physicians is a very sensitive and specific diagnostic tool for most thoracic emergencies; 3) cardiopulmonary resuscitation initiated by lay-rescuers improves short and long-term outcome; 4) no anticoagulant treatment is warranted in distal deep vein thrombosis and 5) systematic unenhanced abdominal CT might improve evaluation of elderly patients with acute abdominal pain...
January 10, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29325842/use-of-dexmedetomidine-in-cardiothoracic-and-vascular-anesthesia
#16
REVIEW
Lucía Gallego-Ligorit, Marc Vives, Jorge Vallés-Torres, T Alberto Sanjuán-Villarreal, Azucena Pajares, Mario Iglesias
Dexmedetomidine is a highly selective α2-adrenergic agonist with analgesic and sedative properties. In the United States, the Food and Drug Administration approved the use of the drug for short-lasting sedation (24 h) in intensive care units (ICUs) in patients undergoing mechanical ventilation and endotracheal intubation. In October 2008, the Food and Drug Administration extended use of the drug for the sedation of nonintubated patients before and during surgical and nonsurgical procedures. In the European Union, the European Medicine Agency approved the use of dexmedetomidine in September 2011 with a single recognized indication: ICU adult patients requiring mild sedation and awakening in response to verbal stimulus...
December 2, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29323623/bladder-management-practices-in-spinal-cord-injury-patients-a-single-center-experience-from-a-developing-country
#17
Sahibzada Nasir Mansoor, Farooq Azam Rathore
CONTEXT/OBJECTIVE: Inadequate bladder management in spinal cord injury (SCI) patients results in significant morbidity and even mortality. Clean intermittent catheterization (CIC) is the recommended option for SCI patients. The objective of the study was to document the bladder management practices of SCI patients in a developing country. DESIGN: Questionnaire based cross sectional survey Setting: Armed Forces Institute of Rehabilitation Medicine, Rawalpindi, Pakistan Participants: All patients with SCI (irrespective of duration, level and etiology) Interventions: Data documentation included demographics, level, severity and time since injury, bladder management techniques used, details of CIC, results of Urodynamic studies (if available), complications resulting from bladder management technique and patient awareness of the yearly follow up...
January 11, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29318026/broncholithiasis-associated-with-lower-airway-inflammation-and-subsequent-pyothorax-in-a-cat
#18
Ferran Valls Sanchez, Jennifer Stewart, Catherine Bovens, Jordi Puig
Case summary: A 12-year-old female spayed domestic shorthair cat presented with history of a long-term chronic cough that had worsened during the previous 2 months. Thoracic radiographs revealed numerous mineral opacities throughout the lung fields. Multiple bronchial plugs of pale yellow material were present on bronchoscopy, consistent with broncholithiasis. Bronchoalveolar lavage cytology revealed a mild neutrophilic inflammation and bacterial culture was negative. The cat was diagnosed with chronic inflammatory lower airway disease and broncholithiasis, suspected to be due to mineralisation of secretions in the bronchial lumen...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29312778/visiting-scholarships-in-cardio-thoracic-surgery-a-valuable-experience-for-fostering-collaboration
#19
Monisha Sudarshan, Stephen D Cassivi
Visiting scholarships to other institutions have a rich history in medicine and are an exciting opportunity to exchange ideas, learn new clinical techniques and form collaborative relationships for research advancements. Such experiences are also important in fostering a well-rounded surgical education. In this article we reflect on the valuable nature of international collaboration and provide a few guidelines to optimize the experience.
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29300374/clinical-history-and-management-recommendations-of-the-smooth-muscle-dysfunction-syndrome-due-to-acta2-arginine-179-alterations
#20
Ellen S Regalado, Lauren Mellor-Crummey, Julie De Backer, Alan C Braverman, Lesley Ades, Susan Benedict, Timothy J Bradley, M Elizabeth Brickner, Kathryn C Chatfield, Anne Child, Cori Feist, Kathryn W Holmes, Glen Iannucci, Birgit Lorenz, Paul Mark, Takayuki Morisaki, Hiroko Morisaki, Shaine A Morris, Anna L Mitchell, John R Ostergaard, Julie Richer, Denver Sallee, Sherene Shalhub, Mustafa Tekin, Anthony Estrera, Patricia Musolino, Anji Yetman, Reed Pyeritz, Dianna M Milewicz
PurposeSmooth muscle dysfunction syndrome (SMDS) due to heterozygous ACTA2 arginine 179 alterations is characterized by patent ductus arteriosus, vasculopathy (aneurysm and occlusive lesions), pulmonary arterial hypertension, and other complications in smooth muscle-dependent organs. We sought to define the clinical history of SMDS to develop recommendations for evaluation and management.MethodsMedical records of 33 patients with SMDS (median age 12 years) were abstracted and analyzed.ResultsAll patients had congenital mydriasis and related pupillary abnormalities at birth and presented in infancy with a patent ductus arteriosus or aortopulmonary window...
January 4, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
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