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https://www.readbyqxmd.com/read/29166722/-value-of-bedside-echocardiography-in-diagnosis-and-risk-assessment-of-in-hospital-death-for-patients-with-stanford-type-a-aortic-dissection
#1
H J Wang, Z Y Xiao, G R Gu, Y Xue, M Shao, Z Deng, Z G Tao, C L Yao, C Y Tong
Objective: To investigate the value of bedside echocardiography in diagnosis and risk assessment of in-hospital death of patients with Stanford type A aortic dissection. Methods: The clinical data of 229 patients with Stanford type A aortic dissection diagnosed by CT angiography in Zhongshan Hospital affiliated to Fudan University between January 2009 and January 2016 were retrospectively analyzed. The patients were divided into survival group(191 cases)and non-survival group(38 cases)according to presence or absence of in-hospital death...
November 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29166709/-effects-of-dexmedetomidine-on-myocardium-of-rats-with-severe-burn-at-early-stage
#2
D Wang, P L Yang, X Zhang, Y Liu
Objective: To investigate the effects of dexmedetomidine on myocardium of rats at early stage after severe burn. Methods: Twenty specific pathogen free male SD rats were immersed in 90 ℃ hot water for 20 s, causing 30% total body surface area (TBSA) full-thickness scald (hereafter referred to as burn) on the back. And then they were divided into burn resuscitation group (BR) and burn resuscitation+ dexmedetomidine group (BRD) according to the random number table, with 10 rats in each group. Sodium lactate Ringer's solution (2 mL·kg(-1)·%TBSA(-1)) were intraperitoneally injected into rats of both groups after burn...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166455/progression-and-prognosis-of-paravalvular-regurgitation-after-transcatheter-aortic-valve-implantation
#3
Rafael Alexandre Meneguz-Moreno, Antônio de Castro-Filho, Auristela Isabel de Oliveira Ramos, Mayra Zumarraga, David Le Bihan, Rodrigo Barretto, Dimytri Alexandre de Alvim Siqueira, Alexandre Antonio Cunha Abizaid, Amanda Guerra de Moraes Rego Sousa, J Eduardo Sousa
BACKGROUND: The impact of paravalvular regurgitation (PVR) following transcatheter aortic valve implantation (TAVI) remains uncertain. OBJECTIVE: To evaluate the impact of PVR on mortality and hospital readmission one year after TAVI. METHODS: Between January 2009 and June 2015, a total of 251 patients underwent TAVI with three different prostheses at two cardiology centers. Patients were assessed according to PVR severity after the procedure...
November 13, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29164946/chronic-heart-failure-management-in-primary-healthcare-in-poland-results-of-a-nationwide-cross-sectional-study
#4
Barbara Wizner, Małgorzata Fedyk-Łukasik, Grzegorz Opolski, Tomasz Zdrojewski, Adam Windak, Marcin Czech, Jacek S Dubiel, Michał Marchel, Krzysztof Rewiuk, Tomasz Rywik, Jerzy Korewicki, Tomasz Grodzicki
BACKGROUND: Organizational and educational activities in primary care in Poland have been introduced to improve the chronic heart failure (CHF) management. OBJECTIVES: To assess the use of diagnostic procedures, pharmacotherapy and referrals of CHF in primary care in Poland. METHODS: The cross-sectional survey was conducted in 2013, involving 390 primary care centres randomly selected from a national database. Trained nurses contacted primary care physicians who retrospectively filled out the study questionnaires on the previous year's CHF management in the last five patients who had recently visited their office...
November 22, 2017: European Journal of General Practice
https://www.readbyqxmd.com/read/29164920/cardiac-structure-and-function-predicts-functional-decline-in-the-oldest-old
#5
David Leibowitz, Jeremy M Jacobs, Irit Lande-Stessman, Dan Gilon, Jochanan Stessman
Background This study examined the association between cardiac structure and function and the deterioration in activities of daily living (ADLs) in an age-homogenous, community-dwelling population of patients born in 1920-1921 over a five-year follow-up period. Design Longitudinal cohort study. Methods Patients were recruited from the Jerusalem Longitudinal Cohort Study, which has followed an age-homogenous cohort of Jerusalem residents born in 1920-1921. Patients underwent home echocardiography and were followed up for five years...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29164849/an-emulsion-hydrogel-soft-motor-actuated-by-thermal-stimulation
#6
Hui Wang, Yuling Liang, Wei Gao, Renfeng Dong, Chaoyang Wang
An emulsion hydrogel motor (E-H-motor) constituted by low-boiling oil fuel and hydrogel matrix, is prepared through a simple yet versatile oil-in-water (O/W) emulsion template method. The E-H-motor can be efficiently propelled by the bubbles generated under thermal stimulus. As thermal-inducted explosion occurs inside the E-H-motor (diameter ~4.0 mm, length ~6.0 mm), the gas bubbles resulting from thermotropic phase transition are violently ejected from one side, leading to a fast speed of 14.78 ± 4.82 mm s-1 in a 60 oC aqueous solution...
November 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29164840/correlations-between-anterior-wall-motion-velocity-of-ascending-aorta-measured-by-quantitative-tissue-velocity-image-and-left-ventricular-geometry-as-well-as-left-heart-function-in-hypertension-patients
#7
Chunyue Luo, Yan Liu, Zuojia Li, Jianying Lin, Ru Chen, Tieshan Zhang, Ying Hu, Guanxun Cheng
BACKGROUD: This study aimed to analyze the correlations between anterior wall motion velocity of ascending aorta measured by quantitative tissue velocity image (QTVI) technique and left ventricular geometry as well as left heart function to evaluate its value of clinical application. METHODS: 110 hypertension patients and 35 healthy controls were included. left ventricular concentric remodeling group and left ventricular hypertrophy group. The QTVI technique was used to obtain the velocity curve of anterior wall of ascending aorta, the peak systolic velocity (Vs), peak velocity of early diastolic motion (Ve) and peak velocity of late diastolic motion (Va)...
November 22, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29164797/impact-of-systolic-blood-pressure-on-the-safety-and-tolerability-of-initiating-and-up-titrating-sacubitril-valsartan-in-patients-with-heart-failure-and-reduced-ejection-fraction-insights-from-the-titration-study
#8
Michele Senni, John J V McMurray, Rolf Wachter, Hugh F McIntyre, Inder S Anand, Vincenzo Duino, Arnab Sarkar, Victor Shi, Alan Charney
AIMS: The TITRATION trial investigated two strategies to initiate and up-titrate sacubitril/valsartan (LCZ696) to the same target dose, over a condensed (3-week) or conservative (6-week) period, in patients with heart failure with reduced ejection fraction (HFrEF) and systolic blood pressure (SBP) of ≥100 mmHg. This post hoc analysis examined the relationship between baseline SBP at screening and achievement of the target dose of sacubitril/valsartan of 97 mg/103 mg (also termed 'LCZ696 200 mg') twice per day during the study...
November 22, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29164753/prevalence-of-left-ventricular-systolic-dysfunction-in-pre-dialysis-and-dialysis-patients-with-preserved-left-ventricular-ejection-fraction
#9
Liselotte C R Hensen, Kathleen Goossens, Victoria Delgado, Rachid Abou, Joris I Rotmans, J Wouter Jukema, Jeroen J Bax
AIMS: Patients with chronic kidney disease (CKD) have an excess of cardiovascular morbidity and mortality, with heart failure (HF) being particularly frequent. Reduced left ventricular ejection fraction (LVEF) defines left ventricular (LV) systolic dysfunction and is associated with poor prognosis. However, CKD patients may have HF symptoms with preserved LVEF. In this subgroup of patients, two-dimensional speckle tracking echocardiography can detect LV systolic dysfunction by analysing LV myocardial deformation...
November 21, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29164397/factors-for-time-to-trastuzumab-induced-cardiotoxicity-in-breast-cancer-patients
#10
Mi Hyung Lee, Jeong Yee, Young Ju Kim, Jin Young Moon, Joo Hee Kim, Sandy Jeong Rhie, Hye Sun Gwak
Trastuzumab is a drug used for the treatment of metastatic breast cancer patients. Due to blockage of the human epidermal growth factor receptor 2 signaling in cardiac myocytes, cardiotoxicity has been observed. There are many studies that investigated risk factors for trastuzumab-induced cardiotoxicity, but no study has been published for factors on the time to cardiotoxicity. This study aimed to investigate the factors for the time to occur trastuzumab-induced cardiotoxicity. From January 2014 to December 2015, a retrospective study was performed with breast cancer patients who were treated with trastuzumab...
November 21, 2017: Medical Oncology
https://www.readbyqxmd.com/read/29164390/nutrition-and-mobility-predict-all-cause-mortality-in-patients-12%C3%A2-months-after-transcatheter-aortic-valve-implantation
#11
Sarah Eichler, Annett Salzwedel, Axel Harnath, Christian Butter, Karl Wegscheider, Mihai Chiorean, Heinz Völler, Rona Reibis
BACKGROUND: The aim of the study was to determine pre-interventional predictors for all-cause mortality in patients after transcatheter aortic valve implantation (TAVI) with a 12-month follow-up. METHODS: From 10/2013 to 07/2015, 344 patients (80.9 ± 5.0 years, 44.5% male) with an elective TAVI were consecutively enrolled prospectively in a multicentre cohort study. Prior to the intervention, sociodemographic parameters, echocardiographic data and comorbidities were documented...
November 21, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29164200/visualizing-rotational-wave-functions-of-electronically-excited-nitric-oxide-molecules-by-using-an-ion-imaging-technique
#12
Kenta Mizuse, Nao Chizuwa, Dai Ikeda, Takashi Imajo, Yasuhiro Ohshima
Here we report the dissociative ionization imaging of electronically excited nitric oxide (NO) molecules to visualize rotational wave functions in the electronic excited state (A (2)Σ(+)). The NO molecules were excited to a single rotational energy eigenstate in the first electronic excited state by a resonant nanosecond ultraviolet pulse. The molecules were then irradiated by a strong, circularly polarized femtosecond imaging pulse. Spatial distribution of the ejected N(+) and O(+) fragment ions from the dissociative NO(2+) was recorded as a direct measure of the molecular axis distribution using a high-resolution slice ion imaging apparatus...
November 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29163163/guanxin-danshen-formulation-protects-against-myocardial-ischemia-reperfusion-injury-induced-left-ventricular-remodeling-by-upregulating-estrogen-receptor-%C3%AE
#13
Xuehong Deng, Xiaoyan Xing, Guibo Sun, Xudong Xu, Haifeng Wu, Guang Li, Xiaobo Sun
Background: Guanxin Danshen formulation (GXDSF) is a traditional Chinese herbal recipe recorded in the Chinese Pharmacopeia since 1995 edition, which consists of Salviae miltiorrhizae Radix et Rhizoma, Notoginseng Radix et Rhizoma and Dalbergiae odoriferae Lignum. Our previous research suggested GXDSF had positive effect on cardiovascular disease. Therefore, the aim of this study was to elucidate the effects of GXDSF on myocardial ischemia reperfusion injury-induced left ventricular remodelling (MIRI-LVR). Methods: The effects of GXDSF on cardiac function were detected by haemodynamics and echocardiograms...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29162360/sleep-disordered-breathing-in-heart-failure-the-state-of-the-art-after-the-serve-hf-trial
#14
REVIEW
João Carmo, Inês Araújo, Filipa Marques, Cândida Fonseca
Heart failure (HF) is one of the most prevalent conditions worldwide and despite therapeutic advances, its prognosis remains poor. Among the multiple comorbidities in HF, sleep-disordered breathing (SDB) is frequent and worsens the prognosis. Preliminary observational studies suggested that treatment of SDB could modify the prognosis of HF, and the issue has gained importance in recent years. The diagnosis of SDB is expensive, slow and suboptimal, and there is thus a need for screening devices that are easier to use and validated in this population...
November 18, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29161956/percutaneous-repair-of-mitral-valve-regurgitation-in-patients-with-severe-heart-failure-comparison-with-optimal-medical-treatment
#15
Nicolas Geis, Philip Raake, Markus Lewening, Derliz Mereles, Emmanuel Chorianopoulos, Lutz Frankenstein, Hugo A Katus, Raffi Bekeredjian, Sven T Pleger
BACKGROUND: Occurrence of severe mitral valve (MV) regurgitation (MR) is an independent negative predictor of mortality in patients with severe systolic heart failure (HF). This study examines clinical effects and cardiac reverse remodelling in patients with severe systolic HF receiving percutaneous mitral valve repair (PMVR) using MitraClip in comparison to patients receiving optimal medical therapy only. METHODS: Between 2010 and 2014, 86 patients (Society of Thoracic Surgeons score: 10...
November 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/29161389/innovations-in-management-of-cardiac-disease-drugs-treatment-strategies-and-technology
#16
P Foëx
Within the last generation, the management of patients with heart disease has been transformed by advances in drug treatments, interventions and diagnostic technologies. The management of arterial hypertension saw beta-blockers demoted from first- to third-line treatment. Recent studies suggest that the goal of treatment may have to change to lower systolic blood pressures to prevent long-term organ damage. Today less than 15% of coronary revascularizations are surgical and more than 85% are done by interventional cardiologists inserting coronary stents...
December 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29160305/a-brief-visit-from-a-red-and-extremely-elongated-interstellar-asteroid
#17
Karen J Meech, Robert Weryk, Marco Micheli, Jan T Kleyna, Olivier R Hainaut, Robert Jedicke, Richard J Wainscoat, Kenneth C Chambers, Jacqueline V Keane, Andreea Petric, Larry Denneau, Eugene Magnier, Travis Berger, Mark E Huber, Heather Flewelling, Chris Waters, Eva Schunova-Lilly, Serge Chastel
None of the approximately 750,000 known asteroids and comets is thought to have originated outside our Solar System, but formation models suggest that orbital migration of the giant planets ejected a large fraction of the original planetesimals into interstellar space(1). The predicted interstellar number density(2) of icy interstellar objects of 2.4 × 10(-4) au(-3) suggested that these should have been detected by surveys, yet hitherto none had been seen. Many decades of asteroid and comet characterization have yielded formation models that explain the mass distribution, chemical abundances and planetary configuration of today's Solar System, but until now there has been no way to tell if our Solar System is typical...
November 20, 2017: Nature
https://www.readbyqxmd.com/read/29159270/the-circular-rna-micra-for-risk-stratification-after-myocardial-infarction
#18
Antonio Salgado-Somoza, Lu Zhang, Melanie Vausort, Yvan Devaux
Background: A significant proportion of patients develop heart failure (HF) after acute myocardial infarction (MI). Predicting this development with novel biomarkers would allow tailoring healthcare to each individual. We recently identified a circular RNA called MICRA which was associated with HF development after MI. Here, we tested whether MICRA was able to risk stratify MI patients. Methods: MICRA was assessed in whole blood samples collected at reperfusion in 472 patients with acute MI...
December 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/29158846/subcellular-localization-of-survivin-determines-its-function-in-cardiomyocytes
#19
Tien-Jui Tsang, Ying-Chang Hsueh, Erika I Wei, David J Lundy, Bill Cheng, You-Tzung Chen, Shoei-Shen Wang, Patrick C H Hsieh
Rationale: Reducing cardiomyocyte death and enhancing their proliferation after myocardial infarction is perhaps the single largest challenge for cardiac tissue regeneration. Survivin (SVV) is the smallest member of the inhibitor of apoptosis (IAP) family but plays two important roles; inhibiting caspase-9 activation in the intrinsic apoptosis pathway, and regulating microtubule dynamics and chromosome segregation during cell division. Genetic depletion of cardiac SVV leads to incomplete cardiomyocyte division and abnormal heart development...
2017: Theranostics
https://www.readbyqxmd.com/read/29158839/characterization-of-cardiac-dynamics-in-an-acute-myocardial-infarction-model-by-four-dimensional-optoacoustic-and-magnetic-resonance-imaging
#20
Hsiao-Chun Amy Lin, Xosé Luís Déan-Ben, Ivana Ivankovic, Melanie A Kimm, Katja Kosanke, Helena Haas, Reinhard Meier, Fabian Lohöfer, Moritz Wildgruber, Daniel Razansky
Extraction of murine cardiac functional parameters on a beat-by-beat basis is limited with the existing imaging modalities due to insufficient three-dimensional temporal resolution. Faster volumetric imaging methods enabling in vivo characterization of functional parameters are poised to advance cardiovascular research and provide a better understanding of the mechanisms underlying cardiac diseases. We present a new approach based on analyzing contrast-enhanced optoacoustic (OA) images acquired at high volumetric frame rate without using cardiac gating or other approaches for motion correction...
2017: Theranostics
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