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https://www.readbyqxmd.com/read/29793053/aggressive-fluid-and-sodium-restriction-in-decompensated-heart-failure-with-preserved-ejection-fraction-results-from-a-randomized-clinical-trial
#1
Karina Sanches Machado d'Almeida, Eneida Rejane Rabelo-Silva, Gabriela Corrêa Souza, Melina Maria Trojahn, Sofia Louise Santin Barilli, Graziella Aliti, Luís Eduardo Rohde, Andreia Biolo, Luís Beck-da-Silva
OBJECTIVES: Sodium and fluid restriction is commonly prescribed for heart failure patients. However, its role in the treatment of heart failure with preserved ejection fraction (HFpEF) remains unclear. The aim of this study was to compare the effect of a diet with sodium and fluid restriction with an unrestricted diet in patients admitted for decompensated HFpEF. METHODS: Patients were randomized to a diet with sodium (0.8 g/d) and fluid (800 mL/d) restriction (intervention group [IG]) or an unrestricted diet (control group [CG]) and followed for 7 d or hospital discharge...
March 21, 2018: Nutrition
https://www.readbyqxmd.com/read/29792395/how-are-patients-with-heart-failure-treated-in-primary-care
#2
Hélène Vaillant-Roussel, Bruno Pereira, Sylvaine Gibot-Boeuf, Romain Eschalier, Claude Dubray, Rémy Boussageon, Philippe Vorilhon
OBJECTIVE: The aim of this study was to assess the adherence of general practitioners (GPs) to guidelines in patients with heart failure with reduced ejection fraction (HFrEF) and to describe GPs' prescribing behavior regarding patients with heart failure with preserved ejection fraction (HFpEF). MATERIALS AND METHODS: Cross-sectional study as part of the ETIC trial. Five classes of drugs were described: angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs); β-blockers (BBs); mineralocorticoid receptor antagonists (MRAs); diuretics (thiazide or loop diuretics); and digoxin...
May 24, 2018: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29792299/a-simple-evidence-based-approach-to-help-guide-diagnosis-of-heart-failure-with-preserved-ejection-fraction
#3
Yogesh N V Reddy, Rickey E Carter, Masaru Obokata, Margaret M Redfield, Barry A Borlaug
Background -Diagnosis of heart failure with preserved ejection fraction (HFpEF) is challenging in euvolemic patients with dyspnea, and no evidence-based criteria are available. We sought to develop and then validate non-invasive diagnostic criteria that could be used to estimate the likelihood that HFpEF is present among patients with unexplained dyspnea in order to guide further testing. Methods -Consecutive patients with unexplained dyspnea referred for invasive hemodynamic exercise testing were retrospectively evaluated...
May 23, 2018: Circulation
https://www.readbyqxmd.com/read/29792284/influence-of-large-hiatus-hernia-on-cardiac-volumes-a-prospective-observational-cohort-study-by-cardiovascular-magnetic-resonance
#4
Pamela Milito, Massimo Lombardi, Emanuele Asti, Gianluca Bonitta, Dario Fina, Francesco Bandera, Luigi Bonavina
BACKGROUND: Large hiatus hernia (LHH) is often associated with post-prandial dyspnea, palpitations or chest discomfort, but its effect on cardiac volumes and performance is still debated. METHODS AND RESULTS: Before and 3-months after laparoscopic repair, 35 patients underwent cardiovascular magnetic resonance (CMR) in the fasting state and after a standardized meal. Preoperatively, LHH size increased significantly after meal (p < 0.010). Compared to the fasting state, a systematic trend of volume reduction of the cardiac chambers was observed...
May 9, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29790109/value-of-three-dimensional-speckle-tracking-echocardiography-to-assess-left-ventricular-function-in-hyperuricemia-patients
#5
Xiaojie Zhang, Qing Lu, Zhuojun Zhang, Yongle Chen, Yanan Wang, Youngshi Wang, Zheng Li, Lindi Jiang
To assess the value of three-dimensional speckle tracking echocardiography (3D STE) in evaluating the left ventricular (LV) function in hyperuricemia patients. We enrolled 15 healthy controls and 40 hyperuricemia patients and collected and analyzed full-volume 3D STE images of the left ventricle in the apical four-chamber heart view. Laboratory tests and 3D STE parameters, including left ventricular ejection fraction, left ventricular end-diastolic volume, left ventricular end-systolic volume, stroke volume (SV), global longitudinal strain (GLS), and global circumferential strain (GCS), were compared between hyperuricemia patients and healthy controls...
May 22, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29790034/left-atrial-myocardial-dysfunction-after-chronic-abuse-of-anabolic-androgenic-steroids-a-speckle-tracking-echocardiography-analysis
#6
Antonello D'Andrea, Juri Radmilovic, Stefano Caselli, Andreina Carbone, Raffaella Scarafile, Simona Sperlongano, Gianpaolo Tocci, Tiziana Formisano, Francesca Martone, Biagio Liccardo, Michele D'Alto, Eduardo Bossone, Maurizio Galderisi, Paolo Golino
Anabolic-androgenic steroids (AAS) are used by power athletes to improve performance. However, the real effects of the chronic consumption of AAS on cardiovascular structures are subjects of intense debate. To detect by speckle tracking echocardiography (STE) underlying left atrial (LA) dysfunction in athletes abusing AAS and assess possible correlation between LA myocardial function and exercise capacity during cardiopulmonary stress test. 65 top-level competitive bodybuilders were selected (45 males), including 35 athletes misusing AAS for at least 5 years (users), 30 anabolic-free bodybuilders (non-users), compared to 40 age- and sex-matched healthy sedentary controls...
May 22, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29789900/associations-of-sensitive-cardiac-troponin-i-with-left-ventricular-morphology-function-and-prognosis-in-end-stage-renal-disease-patients-with-preserved-ejection-fraction
#7
Kenichiro Otsuka, Koki Nakanishi, Kenei Shimada, Haruo Nakamura, Hitoshi Inanami, Hiroki Nishioka, Kohei Fujimoto, Noriaki Kasayuki, Minoru Yoshiyama
Sensitive cardiac troponin I (cTnI) predicts all-cause and cardiovascular mortality in various clinical settings. However, its clinical significance in hemodialysis (HD) patients with preserved left ventricular ejection fraction (LVEF) has not been fully elucidated. This study investigated the association of cTnI with LV morphology and function, and its long-term outcome in HD patients with preserved LVEF. This prospective study consists of 96 HD patients with preserved LVEF (69 ± 8 years and 63% male) who underwent two-dimensional echocardiographic examination and biomarker tests including cTnI, brain natriuretic peptide, and high-sensitive C-reactive protein...
May 22, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29789662/spraying-dynamics-in-continuous-wave-laser-printing-of-conductive-inks
#8
Pol Sopeña, Sergio González-Torres, Juan Marcos Fernández-Pradas, Pere Serra
Laser-induced forward transfer (LIFT), though usually associated with pulsed lasers, has been recently shown to be feasible for printing liquid inks with continuous wave (CW) lasers. This is remarkable not only because of the advantages that the new approach presents in terms of cost, but also because of the surprising transfer dynamics associated with it. In this work we carry out a study of CW-LIFT aimed at understanding the new transfer dynamics and its correlation with the printing outcomes. The CW-LIFT of lines of Ag ink at different laser powers and scan speeds revealed a range of conditions that allowed printing conductive lines with good electrical properties...
May 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29789184/infused-cardioplegia-index-a-new-tool-to-improve-myocardial-protection-a-cohort-study
#9
J J Jiménez Rivera, C Llanos Jorge, J L Iribarren Sarrías, M Brouard Martín, J Lacalzada Almeida, J L Pérez Vela, R Avalos Pinto, R Pérez Hernández, S Ramos de la Rosa, G Yanes Bowden, R Martínez Sanz
BACKGROUND: Strategies for cardio-protection are essential in coronary artery bypass graft surgery. The authors explored the relationship between cardioplegia volume, left ventricular mass index and ischemia time by means of the infused cardioplegia index and its relationship with post-operative low cardiac output syndrome. DESIGN: All patients undergoing coronary artery bypass graft surgery between January 2013 and December 2015 were included. Low cardiac output syndrome was defined according to criteria of the SEMICYUC's consensus document...
May 19, 2018: Medicina Intensiva
https://www.readbyqxmd.com/read/29788842/veno-arterio-venous-ecmo-for-septic-cardiomyopathy-a-single-centre-experience
#10
Dominik J Vogel, Josie Murray, Adam Z Czapran, Luigi Camporota, Nicholas Ioannou, Chris I S Meadows, Peter B Sherren, Kathleen Daly, Nigel Gooby, Nicholas Barrett
INTRODUCTION: The role of extracorporeal support for patients with septic shock remains unclear. METHODS: We conducted a retrospective analysis of our single-centre experience with veno-arterio-venous extracorporeal membrane oxygenation (VAV ECMO) in adult patients with severe respiratory failure and septic cardiomyopathy. Clinical data was extracted from electronic medical records including a dedicated ECMO referral and follow-up database. RESULTS: Twelve patients were commenced on VAV ECMO for septic cardiomyopathy for a median of four days (IQR 3...
May 2018: Perfusion
https://www.readbyqxmd.com/read/29788101/left-ventricular-stroke-volume-in-severe-aortic-stenosis-and-preserved-left-ventricular-ejection-fraction-prognostic-relevance
#11
Victoria Delgado, Jeroen J Bax
No abstract text is available yet for this article.
May 16, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29788059/impact-of-right-ventricular-volume-and-function-evaluated-using-cardiovascular-magnetic-resonance-imaging-on-outcomes-after-surgical-ventricular-reconstruction
#12
Sachiko Yamazaki, Satoshi Numata, Tomoya Inoue, Keiichi Itatani, Kazuki Morimoto, Suguru Ohira, Kaichiro Manabe, Isao Yokota, Hitoshi Yaku
OBJECTIVES: This study aimed to evaluate whether cardiac magnetic resonance imaging (MRI)-derived right ventricular (RV) assessment can facilitate risk stratification among patients with ischaemic cardiomyopathy who underwent surgical ventricular reconstruction (SVR). METHODS: We retrospectively analysed 53 patients who underwent SVR. The patients were preoperatively evaluated using cardiac MRI. Cine-MRI was acquired for left ventricular (LV) and RV volume. Gadolinium-enhanced MRI was performed to evaluate LV scarring...
May 17, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29788047/haemodynamics-dyspnoea-and-pulmonary-reserve-in-heart-failure-with-preserved-ejection-fraction
#13
Masaru Obokata, Thomas P Olson, Yogesh N V Reddy, Vojtech Melenovsky, Garvan C Kane, Barry A Borlaug
Aims: Increases in left ventricular filling pressure are a fundamental haemodynamic abnormality in heart failure with preserved ejection fraction (HFpEF). However, very little is known regarding how elevated filling pressures cause pulmonary abnormalities or symptoms of dyspnoea. We sought to determine the relationships between simultaneously measured central haemodynamics, symptoms, and lung ventilatory and gas exchange abnormalities during exercise in HFpEF. Methods and results: Subjects with invasively-proven HFpEF (n = 50) and non-cardiac causes of dyspnoea (controls, n = 24) underwent cardiac catheterization at rest and during exercise with simultaneous expired gas analysis...
May 19, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29787998/repeated-superovulation-increases-the-risk-of-osteoporosis-and-cardiovascular-diseases-by-accelerating-ovarian-aging-in-mice
#14
Jinjin Zhang, Zhiwen Lai, Liangyan Shi, Yong Tian, Aiyue Luo, Zheyuan Xu, Xiangyi Ma, Shixuan Wang
Superovulation procedures and assisted reproductive technologies have been widely used to treat couples who have infertility problems. Although generally safe, the superovulation procedures are associated with a series of complications, such as ovarian hyper-stimulation syndrome, thromboembolism, and adnexal torsion. The role of long-term repeated superovulation in ovarian aging and especially in associated disorders such as osteoporosis and cardiovascular diseases is still unclear. In this study, we sought to determine if repeated superovulation by ten cycles of treatment with pregnant mare serum gonadotropin/human chorionic gonadotropin could affect ovarian reserve, ovarian function, bone density and heart function...
May 22, 2018: Aging
https://www.readbyqxmd.com/read/29787691/the-influence-of-spinal-cord-injury-on-breastfeeding-ability-and-behavior
#15
Theodor Holmgren, Amanda H X Lee, Shea Hocaloski, Lynsey J Hamilton, Iris Hellsing, Stacy Elliott, Claes Hultling, Andrei V Krassioukov
BACKGROUND: Lactation dysfunction following spinal cord injury has been noted in the literature. However, researchers have often grouped together all women of physical disability or do not account for injury level. The extent of lactation dysfunction and influence of spinal cord injury on breastfeeding ability and behavior is not well understood. Research aim: This study aimed to identify major barriers to lactation and breastfeeding related to spinal cord injury, specifically comparing high- and low-level injuries...
May 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29786682/-the-implementation-of-the-method-of-enhanced-external-counter-pulsation-for-the-treatment-of-cardiovascular-diseases
#16
V A Badtieva, D N Voroshilova
The cardiovascular diseases occupy a leading place in the structure of overall morbidity affecting the population not only of Russia but also of the majority of the developed countries throughout the world; they thus impose the heavy social and economic burden on both the public healthcare services and the modern society in general. At the same time, systemic atherosclerosis is considered to be one of the most common, severe, and life-threatening condition. Despite the presence of a large number of pharmaceutical and surgical methods for the treatment of this pathology, they are not infrequently lacking the desired effectiveness...
May 21, 2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29786039/role-of-soluble-st2-levels-and-beta-blockers-dosage-on-cardiovascular-events-of-patients-with-unselected-st-segment-elevation-myocardial-infarction
#17
Wei-Ping Huang, Xuan Zheng, Lei He, Xi Su, Cheng-Wei Liu, Ming-Xiang Wu
Background: Serum soluble ST2 (sST2) levels are elevated early after acute myocardial infarction and are related to adverse left ventricular (LV) remodeling and cardiovascular outcomes in ST-segment elevation myocardial infarction (STEMI). Beta-blockers (BB) have been shown to improve LV remodeling and survival. However, the relationship between sST2, final therapeutic BB dose, and cardiovascular outcomes in STEMI patients remains unknown. Methods: A total of 186 STEMI patients were enrolled at the Wuhan Asia Heart Hospital between January 2015 and June 2015...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29785884/morphological-changes-and-myocardial-function-assessed-by-traditional-and-novel-echocardiographic-methods-in-preadolescent-athlete-s-heart
#18
Anders W Bjerring, Hege Ew Landgraff, Svein Leirstein, Anette Aaeng, Hamza Z Ansari, Jørg Saberniak, Klaus Murbræch, Henrik Bruun, Thomas M Stokke, Kristina H Haugaa, Jostein Hallén, Thor Edvardsen, Sebastian I Sarvari
Background Athlete's heart is a term used to describe the morphological and functional changes in the hearts of athletes. Recent studies suggest that these changes may occur even in preadolescent athletes. This study aims to improve our understanding of the changes occurring in the preadolescent athlete's heart. Design and methods Cardiac morphology and function in 76 preadolescent cross-country skiers (aged 12.1 ± 0.2 years) were compared with 25 age-matched non-competing preadolescents. Echocardiography was performed in all subjects, including 2D speckle-tracking strain echocardiography and 3D echocardiography...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29785765/water-molecules-gating-a-photoinduced-one-electron-two-protons-transfer-in-a-tyr-his-model-of-photosystem-ii
#19
Georgios Chararalambidis, Syamal Das, Adelais Trapali, Annamaria Quaranta, Maylis Orio, Zakaria Halime, Pierre Fertey, Régis Guillot, Athanassios Coutsolelos, Winfried Leibl, Ally Aukauloo, Marie Sircoglou
In this report, we investigate on a biomimetic model of a H-bonded TyrZ/His190 pair covalently attached to a porphyrin sensitizer. Laser flash photolysis in presence of an external electron acceptor reveals the need of water molecules to unlock the light-induced oxidation of the phenol through an intramolecular pathway. Kinetics monitoring encompasses two fast phases with distinct spectral properties. The first phase is related to one-electron transfer from the phenol to the porphyrin radical cation coupled with a domino two-proton transfer leading to the ejection of a proton from the imidazole-phenol pair...
May 22, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29785733/left-ventricular-strain-analysis-using-cardiac-mri-in-patients-undergoing-in-centre-nocturnal-hemodialysis
#20
Jann Patrick Ong, Ron Wald, Marc B Goldstein, Jonathon Leipsic, Mercedeh Kiaii, Djeven P Deva, Anish Kirpalani, Laura Jimenez-Juan, Olugbenga Bello, Paymon M Azizi, Rachel M Wald, Graham A Wright, Ziv Harel, Kim A Connelly, Andrew T Yan
AIM: Intensified haemodialysis is associated with regression of left ventricular (LV) mass. Compared to LV ejection fraction, LV strain allows more direct assessment of LV function. We sought to assess the impact of in-centre nocturnal haemodialysis (INHD) on global LV strain (radial, circumferential, and longitudinal) and torsion by cardiac MRI (CMR). METHODS: In this prospective, 2-centre cohort study, 37 participants on conventional haemodialysis (CHD, 3-4 hours/session for 3 sessions/week) converted to INHD (7-8 hours/session for 3 sessions/week) and 30 participants continued CHD...
May 21, 2018: Nephrology
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