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Classification of acute pancreatitis

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https://www.readbyqxmd.com/read/28643979/-acute-pancreatitis-new-aspects-for-the-management
#1
Olivier Windisch, Toni Raffoul, Catrina Hansen, Jean-Louis Frossard, Philippe Morel, Léo Bühler
Acute pancreatitis is a frequent disease, with a simple course in 80 % of the cases but a high morbidity and mortality in its severe form. Biliary origin and alcohol represent 80 % of the etiologies. Except endoscopic removal of gallstone for biliary origin, treatment remains symptomatic and focuses on fluid resuscitation, effective antalgia and adapted management of nutrition. This article focuses on the novelties introduced by the revision of the Classification of Atlanta in 2012 and details current guidelines for the management of the disease...
June 14, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28639336/classification-of-pancreaticobiliary-maljunction-and-clinical-features-in-children
#2
Naoto Urushihara, Yoshinori Hamada, Terumi Kamisawa, Hideki Fujii, Tsugumichi Koshinaga, Yoshiki Morotomi, Takeshi Saito, Takao Itoi, Kenitiro Kaneko, Hiroaki Fukuzawa, Hisami Ando
PURPOSE: In 2015, the Committee on Diagnostic Criteria of the Japanese Study Group on Pancreaticobiliary Maljunction (PBM) proposed a classification of PBM into four types: (A) stenotic type, (B) non-stenotic type, (C) dilated channel type, and (D) complex type. To validate this classification and clarify the clinical features of the four types of PBM, a retrospective multicenter study was conducted. METHODS: We divided the study group of 317 children with PBM into the four types of PBM...
June 21, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28622243/fulminant-or-early-severe-acute-pancreatitis-is-overlooked-by-classifications-of-severity
#3
Wei Huang, John A Windsor
No abstract text is available yet for this article.
July 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28613246/serum-uromodulin-levels-in-prediction-of-acute-kidney-injury-in-the-early-phase-of-acute-pancreatitis
#4
Beata Kuśnierz-Cabala, Agnieszka Gala-Błądzińska, Małgorzata Mazur-Laskowska, Paulina Dumnicka, Mateusz Sporek, Aleksandra Matuszyk, Krzysztof Gil, Piotr Ceranowicz, Jerzy Walocha, Jakub Kucharz, Michał Pędziwiatr, Krzysztof Bartuś, Rafał Trąbka, Marek Kuźniewski
In health, uromodulin is the main protein of urine. Serum uromodulin concentrations (sUMOD) have been shown to correlate with kidney function. Acute kidney injury (AKI) is among the main complications of severe acute pancreatitis (AP). No reports exist on sUMOD in patients with AP, including the diagnostic usefulness for early prediction of AP severity. We measured sUMOD during first 72 h of AP. Sixty-six adult patients with AP were recruited at the surgical ward of the District Hospital in Sucha Beskidzka, Poland...
June 14, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28610827/il-6-and-crp-are-superior-in-early-differentiation-between-mild-and-non-mild-acute-pancreatitis
#5
Hanna Sternby, Hannes Hartman, Dorthe Johansen, Henrik Thorlacius, Sara Regnér
BACKGROUND: The revised Atlanta classification on acute pancreatitis (AP) presents distinct criteria for severity categorization. Due to the lack of reliable prognostic markers, a majority of patients with AP are currently hospitalized and initially managed identically. As incidence and financial costs are rising the need for early severity differentiation will increase. This study aimed to investigate the capacity of biomarkers to stratify AP patients during the initial course of the disease...
May 30, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28604838/effect-of-acute-pancreatitis-on-the-risk-of-developing-osteoporosis-a-nationwide-cohort-study
#6
Shih-Yi Lin, Wu-Huei Hsu, Cheng-Chieh Lin, Cheng-Li Lin, Chung-Hao Tsai, Chia-Hung Kao
PURPOSE: Chronic exocrine pancreatic insufficiency can lead to osteoporosis. However, the incidence and risk of osteoporosis after acute inflammation of pancreas remained known. Thus, we conducted a population-based cohort study to clarify the association between acute pancreatitis (AP) and osteoporosis. METHODS: Patients newly diagnosed with AP with index date between 2000 and 2011 were identified from the National Health Insurance Research Database. Osteoporosis were defined according to the International Classification of Diseases, Ninth Revision, Clinical Modification codes...
2017: PloS One
https://www.readbyqxmd.com/read/28591817/efficacy-of-radiotherapy-for-primary-tumor-in-patients-with-unresectable-pancreatic-neuroendocrine-tumors
#7
Tomoyuki Iwata, Hideki Ueno, Jun Itami, Yoshinori Ito, Koji Inaba, Chigusa Morizane, Shunsuke Kondo, Yasunari Sakamoto, Satoshi Shiba, Mitsuhito Sasaki, Futa Koga, Takuji Okusaka
Background: Detailed information regarding the clinical efficacy of radiotherapy (RT) for primary tumor in patients with unresectable pancreatic neuroendocrine tumors (pNETs) is unknown. We therefore performed a retrospective study to evaluate the efficacy and safety of RT for primary pancreatic tumors in patients with pNETs. Methods: We investigated 11 patients with pNETs who received RT to the primary site between January 1997 and June 2015. Seven patients had Grade 2 neuroendocrine tumors (NET-G2) and four had neuroendocrine carcinoma (NEC) according to the 2010 WHO histopathological classification...
June 7, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28579182/acute-pancreatitis-has-long-term-deleterious-effect-on-physical-quality-of-life
#8
Jorge D Machicado, Amir Gougol, Kimberly Stello, Gong Tang, Yongseok Park, Adam Slivka, David C Whitcomb, Dhiraj Yadav, Georgios I Papachristou
BACKGROUND & AIMS: It is not clear how acute pancreatitis (AP) affects quality of life (QOL). We aimed to determine the long-term independent effect of AP on physical and mental QOL. METHODS: We analyzed data from 91 patients (mean age, 52 year; 54% female) admitted with AP to the University of Pittsburgh Medical Center from 2011 through 2015 who responded to telephone surveys at a median of 14 months after hospital discharge (interquartile range, 12-16 months)...
June 1, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28538626/the-capacity-of-icd-10-cm-pcs-to-characterize-surgical-care
#9
Garth H Utter, Kevin M Schuster, Preston R Miller, Nathan T Mowery, Suresh K Agarwal, Robert J Winchell, Marie L Crandall
The International Classification of Diseases, 10th edition, Clinical Modification and Procedure Coding System (ICD-10-CM/PCS) have been in effect since October 1, 2015 and offer much greater capacity than previous classifications to characterize the nature and treatment of surgical conditions. However, the diagnosis codes of ICD-10-CM are unevenly specific across the spectrum of surgical conditions and currently do not adequately allow description of important distinctions in disease severity for many common surgical conditions...
May 22, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28507751/validation-of-the-efficacy-of-the-prognostic-factor-score-in-the-japanese-severity-criteria-for-severe-acute-pancreatitis-a-large-multicenter-study
#10
Tsukasa Ikeura, Masayasu Horibe, Masamitsu Sanui, Mitsuhito Sasaki, Yasuyuki Kuwagata, Kenichiro Nishi, Shuji Kariya, Hirotaka Sawano, Takashi Goto, Tsuyoshi Hamada, Takuya Oda, Hideto Yasuda, Yuki Ogura, Dai Miyazaki, Kaoru Hirose, Katsuya Kitamura, Nobutaka Chiba, Tetsu Ozaki, Takahiro Yamashita, Toshitaka Koinuma, Taku Oshima, Tomonori Yamamoto, Morihisa Hirota, Satoshi Yamamoto, Kyoji Oe, Tetsuya Ito, Eisuke Iwasaki, Takanori Kanai, Kazuichi Okazaki, Toshihiko Mayumi
BACKGROUND: The Japanese severity criteria for acute pancreatitis (AP), which consist of a prognostic factor score and contrast-enhanced computed tomography grade, have been widely used in Japan. OBJECTIVE: This large multicenter retrospective study was conducted to validate the predictive value of the prognostic factor score for mortality and complications in severe AP patients in comparison to the Acute Physiology and Chronic Health Evaluation II (APACHE II) score...
April 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28494574/endoscopic-management-of-peri-pancreatic-fluid-collections
#11
REVIEW
Hon Chi Yip, Anthony Yuen Bun Teoh
In the past decade, there has been a progressive paradigm shift in the management of peri-pancreatic fluid collections after acute pancreatitis. Refinements in the definitions of fluid collections from the updated Atlanta classification have enabled better communication amongst physicians in an effort to formulate optimal treatments. Endoscopic ultrasound (EUS)-guided drainage of pancreatic pseudocysts has emerged as the procedure of choice over surgical cystogastrostomy. The approach provides similar success rates with low complications and better quality of life compared with surgery...
May 12, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28487729/severity-treatment-and-outcome-of-acute-pancreatitis-in-thailand-the-first-comprehensive-review-using-revised-atlanta-classification
#12
Supot Pongprasobchai, Peeradon Vibhatavata, Piyaporn Apisarnthanarak
Background. Severity and outcome of acute pancreatitis (AP) in Thailand are unknown. Methods. A retrospective study of 250 patients with AP during 2011-2014 was performed. Severity, treatment, and outcome were evaluated. Severity was classified by revised Atlanta classification. Results. The mean age was 58 years and 56% were men. Etiologies were gallstones (45%), alcohol (16%), postendoscopic retrograde cholangiopancreatography (14%), and idiopathic (15%). Overall, 72%, 16%, and 12% of patients had mild, moderately severe, and severe AP, respectively...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28487129/identification-of-potential-diagnostic-biomarkers-of-acute-pancreatitis-by-serum-metabolomic-profiles
#13
Hong Xiao, Jian-Hua Huang, Xing-Wen Zhang, Rida Ahmed, Qing-Ling Xie, Bin Li, Yi-Ming Zhu, Xiong Cai, Qing-Hua Peng, Yu-Hui Qin, Hui-Yong Huang, Wei Wang
Acute pancreatitis (AP) is defined as an acute inflammation of pancreas that may cause damage to other tissues and organs depending upon the severity of symptoms. The diagnosis of AP is usually made by detection of raised circulating pancreatic enzyme levels, but there are occasional false positive and false negative diagnoses and such tests are often normal in delayed presentations. More accurate biomarkers would help in such situations. In this study, the global metabolites' changes of AP patients (APP) were profiled by using gas chromatography-mass spectrometry (GC-MS)...
May 3, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28480730/choledochocele-as-an-atypical-cause-of-relapsing-acute-pancreatitis-diagnosis-and-endoscopic-treatment
#14
Cristina Saldaña Dueñas, Juan José Vila Costa, Ignacio Fernández-Urién
The choledochocele is a cystic dilatation of the intraduodenal portion of the bile duct and corresponds to the type III biliary cysts in the Todani ´s classification. Eventhough the majority of patients remain asymptomatic they can be an atypical cause of abdominal pain or relapsing acute pancreatitis events. The risk of malignancy is lower than other choledochal cyst (<2,5%). The treatment is based on surgical or new endoscopic techniques of resection. In some of the cases an endoscopic sphincterotomy is the first approach...
May 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28436602/accuracy-of-circulating-histones-in-predicting-persistent-organ-failure-and-mortality-in-patients-with-acute-pancreatitis
#15
T Liu, W Huang, P Szatmary, S T Abrams, Y Alhamdi, Z Lin, W Greenhalf, G Wang, R Sutton, C H Toh
BACKGROUND: Early prediction of acute pancreatitis severity remains a challenge. Circulating levels of histones are raised early in mouse models and correlate with disease severity. It was hypothesized that circulating histones predict persistent organ failure in patients with acute pancreatitis. METHODS: Consecutive patients with acute pancreatitis fulfilling inclusion criteria admitted to Royal Liverpool University Hospital were enrolled prospectively between June 2010 and March 2014...
April 24, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28434059/early-warning-score-independently-predicts-adverse-outcome-and-mortality-in-patients-with-acute-pancreatitis
#16
Michael J Jones, Christopher P Neal, Wee Sing Ngu, Ashley R Dennison, Giuseppe Garcea
PURPOSE: The aim of this study was to compare the prognostic value of established scoring systems with early warning scores in a large cohort of patients with acute pancreatitis. METHODS: In patients presenting with acute pancreatitis, age, sex, American Society of Anaesthesiologists (ASA) grade, Modified Glasgow Score, Ranson criteria, APACHE II scores and early warning score (EWS) were recorded for the first 72 h following admission. These variables were compared between survivors and non-survivors, between patients with mild/moderate and severe pancreatitis (based on the 2012 Atlanta Classification) and between patients with a favourable or adverse outcome...
April 22, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28425682/mild-acute-biliary-pancreatitis-the-timing-of-cholecystectomy-should-not-exceed-index-admission
#17
Luca Degrate, Davide P Bernasconi, Paola Meroni, Mattia Garancini, Daniele Macchini, Fabrizio Romano, Fabio Uggeri, Luca Gianotti
BACKGROUND: Laparoscopic cholecystectomy (LC) to treat mild biliary acute pancreatitis (MBAP) during index admission is recommended. However, the optimal surgical timing is controversial, considering that patients are actually often discharged from hospital and readmitted for elective cholecystectomy. Moreover, previous studies showed an uneven patients' stratification for pancreatitis severity. The aim of this study was to determine the outcome of patients homogenously categorised for MBAP according to the newest pancreatitis classifications, undergoing cholecystectomy with different timing...
April 19, 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/28419583/a-comparison-of-multi-factor-scoring-systems-and-single-serum-markers-for-the-early-prediction-of-the-severity-of-acute-pancreatitis
#18
Wen-Hua He, Yin Zhu, Yong Zhu, Qi Jin, Hong-Rong Xu, Zhi-Juan Xion, Min Yu, Liang Xia, Pi Liu, Nong-Hua Lu
BACKGROUND: The purpose of this study was to clarify whether the current scoring systems and single serum markers used in pancreatitis remain applicable for the early prediction of infected pancreatic necrosis (IPN), the severity and mortality of acute pancreatitis (AP) in accordance with the revised Atlanta and determinant-based classifications. METHODS: Demographic, clinical, and laboratory data from 708 consecutive patients with AP were prospectively collected between January 2011 and December 2012...
April 17, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28405150/comparing-acid-steatocrit-and-faecal-elastase-estimations-for-use-in-m-annheim-staging-for-pancreatitis
#19
M Ganesh Kamath, C Ganesh Pai, Asha Kamath, Annamma Kurien
AIM: To compare two tests for exocrine pancreatic function (EPF) for use in M-ANNHEIM staging for pancreatitis. METHODS: One hundred and ninety four consecutive patients with acute pancreatitis (AP; n = 13), recurrent acute pancreatitis (RAP; n = 65) and chronic pancreatitis (CP; n = 116) were enrolled. EPF was assessed by faecal elastase-1 (FE-1) estimation and stool fat excretion by the acid steatocrit method. Patients were classified as per M-ANNHEIM stages separately based on the results of the two tests for comparison...
March 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28403081/evaluation-of-extrapancreatic-inflammation-on-abdominal-computed-tomography-as-an-early-predictor-of-organ-failure-in-acute-pancreatitis-as-defined-by-the-revised-atlanta-classification
#20
Chenyang Chen, Zixing Huang, Hang Li, Bin Song, Fang Yuan
The aim of the study was to determine whether extrapancreatic inflammation on computed tomography (EPIC) is helpful in predicting organ failure in the early phase of acute pancreatitis (AP) as defined by the 2012 revised Atlanta classification.Patients (n = 208) who underwent abdominal computed tomography (CT) within 24 hours after AP onset and admission were retrospectively identified. Each patient's EPIC score, Balthazar score, bedside index of severity in acute pancreatitis (BISAP), and systemic inflammatory response syndrome (SIRS) score were obtained...
April 2017: Medicine (Baltimore)
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