keyword
MENU ▼
Read by QxMD icon Read
search

Neonatal abstinence syndrome

keyword
https://www.readbyqxmd.com/read/29130600/opioid-dependence-and-pregnancy-in-early-twentieth-century-america
#1
Nathan Tauger
BACKGROUND AND AIMS: Research on Neonatal Abstinence Syndrome has prompted discussion over how to ensure best outcomes for pregnant women who use drugs and for drug-dependent newborns. Before Neonatal Abstinence Syndrome and the 1980s panic of "crack babies," turn-of-the-century American medical journals discussed infants born to drug-using mothers. This paper aimed to determine whether women who used drugs while pregnant in early twentieth-century America were subject to the stigma many face today...
November 11, 2017: Addiction
https://www.readbyqxmd.com/read/29112997/comparison-of-neonatal-abstinence-syndrome-treatment-with-sublingual-buprenorphine-versus-conventional-opioids
#2
Eric S Hall, Ward R Rice, Alonzo T Folger, Scott L Wexelblatt
No abstract text is available yet for this article.
November 7, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/29112519/methadone-versus-buprenorphine-for-opioid-use-dependence-and-risk-of-neonatal-abstinence-syndrome
#3
Lara S Lemon, Steve N Caritis, Raman Venkataramanan, Robert W Platt, Lisa M Bodnar
BACKGROUND: Our objective was to estimate the association between methadone and neonatal abstinence syndrome compared with buprenorphine using a probabilistic bias analysis to account for unmeasured confounding by severity of addiction. METHODS: We used a cohort of live-born infants exposed in utero to methadone or buprenorphine for maternal opioid maintenance therapy at Magee-Womens Hospital in Pittsburgh, PA from 2013-2015 (n=716). We determined exposure and outcome status using pharmacy billing claims...
November 6, 2017: Epidemiology
https://www.readbyqxmd.com/read/29105752/buprenorphine-in-the-neonatal-abstinence-syndrome
#4
REVIEW
Walter K Kraft
No abstract text is available yet for this article.
November 6, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29094858/neonatal-abstinence-syndrome-and-maternal-substance-use-in-wisconsin-2009-2014
#5
Karina A Atwell, Harold B Weiss, Crystal Gibson, Richard Miller, Timothy E Corden
INTRODUCTION: Increasing rates of neonatal abstinence syndrome (NAS), most commonly linked to maternal opioid use, are a growing concern within clinical and public health domains. OBJECTIVES: The study aims to describe the statewide burden of NAS and maternal substance use, focusing on opioids in Wisconsin from 2009 to 2014. METHODS: Trends in NAS and maternal substance use diagnosis rates were calculated using Wisconsin’s Hospital Discharge Data...
December 2016: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29070156/born-into-addiction-neonatal-abstinence-syndrome-and-pediatric-dentistry
#6
Jennifer L Cully
Drug overdose and opioid-involved deaths continue to increase across the United States. An end-condition related to opioid abuse is neonatal abstinence syndrome (NAS). The implications for pregnant or post-partum women using an opioid, whether prescribed or illicit, can have significant effects on their infant. First described in the 1970s, NAS is defined as a postnatal drug withdrawal syndrome that primarily occurs in opioid-exposed infants. There are no nationally accepted, evidence-based treatment protocols for these infants...
September 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29068826/opioid-addiction-in-pregnancy-does-depression-negatively-impact-adherence-with-prenatal-care
#7
Lauren Hensley, Suela Sulo, Sarah Kozmic, Barbara V Parilla
OBJECTIVE: We aimed to evaluate whether depression in pregnancy in women with opioid dependency negatively impacts adherence with prenatal care. METHODS: This was a retrospective chart analysis of opioid-dependent pregnant women over a 6-year period at 2 large referral and tertiary care centers. The primary outcome was adherence with prenatal care based on the concurrent diagnosis of depression. Adherence was assessed by looking at the number of observed versus expected prenatal visits...
October 24, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29067285/decreasing-total-medication-exposure-and-length-of-stay-while-completing-withdrawal-for-neonatal-abstinence-syndrome-during-the-neonatal-hospital-stay
#8
Lori A Devlin, Timothy Lau, Paula G Radmacher
INTRODUCTION: Neonatal abstinence syndrome (NAS) is a rapidly growing public health concern that has considerably increased health-care utilization and health-care costs. In an effort to curtail costs, attempts have been made to complete withdrawal as an outpatient. Outpatient therapy has been shown to prolong exposure to medications, which may negatively impact neurodevelopmental and behavioral outcomes. We hypothesized that the implementation of a modified NAS protocol would decrease total drug exposure and length of stay while allowing for complete acute drug withdrawal during the neonatal hospital stay...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29048415/antenatal-methadone-vs-buprenorphine-exposure-and-length-of-hospital-stay-in-infants-admitted-to-the-intensive-care-unit-with-neonatal-abstinence-syndrome
#9
V N Tolia, K Murthy, M M Bennett, E S Miller, D K Benjamin, P B Smith, R H Clark
OBJECTIVE: Antenatal exposure to methadone or buprenorphine often causes neonatal abstinence syndrome (NAS) in newborns. However, comparative effects on affected infants' hospital courses are inconclusive. We sought to estimate the relationship of antenatal exposure with methadone or buprenorphine and infants' length of stay among hospitalized infants with NAS. STUDY DESIGN: This was a retrospective cohort study of hospitalized infants with NAS with either maternal exposure...
October 19, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29046872/swallow-breath-interaction-and-phase-of-respiration-with-swallow-during-non-nutritive-suck-in-infants-affected-by-neonatal-abstinence-syndrome
#10
Eric W Reynolds, Debbie Grider, Cynthia S Bell
BACKGROUND: The development of suck-swallow-breath rhythms during non-nutritive suck (NNS) may be an indicator of neurologic integrity. We have described swallow-breath (SwBr) interaction and phase of respiration (POR) with swallow during NNS in low-risk preterm (LRP) infants. NNS in infants with neonatal abstinence syndrome (NAS) has not been described with our method. METHOD: Suckle, swallow, thoracic motion, and nasal airflow were measured during NNS in 10 infants with NAS and 12 unaffected infants (control)...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29045256/a-quality-improvement-initiative-to-increase-scoring-consistency-and-accuracy-of-the-finnegan-tool-challenges-in-obtaining-reliable-assessments-of-drug-withdrawal-in-neonatal-abstinence-syndrome
#11
Wendy Timpson, Cheryl Killoran, Louise Maranda, Alan Picarillo, Elisabeth Bloch-Salisbury
BACKGROUND: Current practice for diagnosing neonatal abstinence syndrome and guiding pharmacological management of neonatal drug withdrawal is dependent on nursing assessments and repeated evaluation of clinical signs. PURPOSE: This single-center quality improvement initiative was designed to improve accuracy and consistency of Finnegan scores among neonatal nurses. METHODS: One-hundred seventy neonatal nurses participated in a single-session withdrawal-assessment program that incorporated education, scoring guidelines, and a restructured Finnegan scale...
October 17, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28990851/stability-study-of-a-clonidine-oral-solution-in-a-novel-vehicle-designed-for-pediatric-patients
#12
Arnaud Potier, Julien Voyat, Alain Nicolas
Clonidine hydrochloride is administered to opioid-addicted mothers' neonates to reduce neonatal abstinence syndrome. It is prescribed off-label to neonates at 0.5-1 µg/kg/6 h, alone or in combination. The commercially injectable form of clonidine-Catapressan(®) 0.15 mg/mL-is being orally given after an appropriate dilution in water. However, this practice is not suitable for a perfectly safe and accurate administration. The objectives were to design a 10 µg/mL oral solution of clonidine hydrochloride in Inorpha(®) and to study the stability of this solution by a validated stability-indicating liquid chromatography (LC) method...
October 24, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28979894/judging-the-neonatal-abstinence-syndrome-assessment-tools-to-guide-future-tool-development-the-use-of-clinimetrics-as-opposed-to-psychometrics
#13
REVIEW
Philip M Westgate, Enrique Gomez-Pomar
In the face of the current Neonatal Abstinence Syndrome (NAS) epidemic, there is considerable variability in the assessment and management of infants with NAS. In this manuscript, we particularly focus on NAS assessment, with special attention given to the popular Finnegan Neonatal Abstinence Score (FNAS). A major instigator of the problem of variable practices is that multiple modified versions of the FNAS exist and continue to be proposed, including shortened versions. Furthermore, the validity of such assessment tools has been questioned, and as a result, the need for better tools has been suggested...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28963285/simplification-of-the-finnegan-neonatal-abstinence-scoring-system-retrospective-study-of-two-institutions-in-the-usa
#14
Enrique Gomez Pomar, Loretta P Finnegan, Lori Devlin, Henrietta Bada, Vanessa A Concina, Katrina T Ibonia, Philip M Westgate
OBJECTIVE: To develop a simplified Finnegan Neonatal Abstinence Scoring System (sFNAS) that will highly correlate with scores ≥8 and ≥12 in infants being assessed with the FNAS. DESIGN, SETTING AND PARTICIPANTS: This is a retrospective analysis involving 367 patients admitted to two level IV neonatal intensive care units with a total of 40 294 observations. Inclusion criteria included neonates with gestational age ≥37 0/7 weeks, who are being assessed for neonatal abstinence syndrome (NAS) using the FNAS...
September 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28949409/the-effect-of-morphine-dosing-on-length-of-stay-in-neonatal-abstinence-syndrome-an-alternative-viewpoint
#15
Kirsten H Ohler, Jennifer T Pham
No abstract text is available yet for this article.
September 26, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28941590/method-performance-and-clinical-workflow-outcomes-associated-with-meconium-and-umbilical-cord-toxicology-testing
#16
Ruth M Labardee, Jaime R Swartzwelder, Karen E Gebhardt, Justine A Pardi, Anna C Dawsey, R Brent Dixon, Steven W Cotten
OBJECTIVE: Neonatal abstinence syndrome (NAS) is a rising concern with unknown long-term effects. It is apparent that higher cost of care, impact on the community and reduced quality of life are associated with similar etiologies (e.g., fetal alcohol syndrome). Detection of drug exposure in utero allows for earlier intervention to potentially reduce undesired outcomes. Umbilical cord tissue (UCT) has been documented as a readily accessible specimen for detection of drug exposure and has emerged as an alternative specimen to meconium...
September 21, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28917206/maternal-and-infant-outcomes-following-third-trimester-exposure-to-marijuana-in-opioid-dependent-pregnant-women-maintained-on-buprenorphine
#17
Alane B O'Connor, Brandon K Kelly, Liam M O'Brien
BACKGROUND: To determine whether maternal and infant outcomes are associated with exposure to marijuana during the third trimester in a population of opioid dependent pregnant women maintained on buprenorphine. METHODS: This retrospective cohort study of 191 maternal-infant dyads exposed to buprenorphine during pregnancy examines a variety of variables including gestational age, birthweight, method of delivery, Apgar scores at one and five minutes, duration of infant hospital stay, peak neonatal abstinence syndrome (NAS) score, duration of NAS and incidence of pharmacologic treatment of NAS in infants exposed to marijuana during the third trimester as compared to infants not exposed to marijuana during the third trimester...
November 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28891099/opioid-and-benzodiazepine-weaning-in-pediatric-patients-review-of-current-literature
#18
Norman E Fenn, Kimberly S Plake
Pediatric opioid and benzodiazepine withdrawal are avoidable complications of pain and sedation management that is well described in the literature. To prevent withdrawal from occurring, practitioners regularly use a steady decrease of pain and sedation medications, also known as a weaning or tapering schedule. The weaning schedule is highly variable based on clinician preference and is usually dependent on the clinician. The purposes of this review are to evaluate the current literature on the process of opioid and benzodiazepine weaning in pediatric patients and to assess the various standardized protocols used to decrease withdrawal occurrences...
September 11, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28879171/the-genomics-of-neonatal-abstinence-syndrome
#19
REVIEW
F Sessions Cole, Daniel J Wegner, Jonathan M Davis
Significant variability has been observed in the development and severity of neonatal abstinence syndrome (NAS) among neonates exposed to prenatal opioids. Since maternal opioid dose does not appear to correlate directly with neonatal outcome, maternal, placental, and fetal genomic variants may play important roles in NAS. Previous studies in small cohorts have demonstrated associations of variants in maternal and infant genes that encode the μ-opioid receptor (OPRM1), catechol-O-methyltransferase (COMT), and prepronociceptin (PNOC) with a shorter length of hospital stay and less need for treatment in neonates exposed to opioids in utero...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28877016/buprenorphine-for-the-neonatal-abstinence-syndrome
#20
LETTER
Walter K Kraft, Susan C Adeniyi-Jones, Michelle E Ehrlich
New England Journal of Medicine, Volume 377, Issue 10, Page 996-998, September 2017.
September 7, 2017: New England Journal of Medicine
keyword
keyword
2833
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"