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Drinking motives

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https://www.readbyqxmd.com/read/27914226/drinking-motives-and-alcohol-outcome-expectancies-as-mediators-of-the-association-between-negative-urgency-and-alcohol-consumption
#1
Amber M Anthenien, Jordanna Lembo, Clayton Neighbors
OBJECTIVE: To determine whether the effects of negative urgency, a unique facet of impulsivity marked by engaging in potentially unhealthy and rash behaviors in order to cope with anxiety or negative moods, on drinking behavior can be explained by positive and negative alcohol outcome expectancies and specific drinking motives (i.e., coping and enhancement). METHODS: College students (N=194) completed web-based surveys in exchange for course credit. Students completed measures of negative urgency, comprehensive effects of alcohol, drinking motives, and alcohol use behaviors...
November 15, 2016: Addictive Behaviors
https://www.readbyqxmd.com/read/27906494/alcohol-dependent-molecular-adaptations-of-the-nmda-receptor-system
#2
REVIEW
Nadege Morisot, Dorit Ron
Phenotypes such as motivation to consume alcohol, goal-directed alcohol seeking and habit formation contribute to the mechanisms underlying heavy alcohol use. Learning and memory processes greatly contribute to the establishment and maintenance of these behavioral phenotypes. The N-Methyl-D-Aspartate receptor (NMDAR) is a driving force of synaptic plasticity, a key cellular hallmark of learning and memory. Here, we describe data in rodents and humans linking signaling molecules that center around the NMDARs and behaviors associated with the development and/or maintenance of alcohol abuse...
December 1, 2016: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/27902943/combat-experience-and-problem-drinking-in-veterans-exploring-the-roles-of-ptsd-coping-motives-and-perceived-stigma
#3
Stephen M Miller, Eric R Pedersen, Grant N Marshall
PURPOSE: The current investigation sought to illustrate the etiology of adverse alcohol consequences in young adult veterans using a path analytic framework. METHODS: A total of 312 veterans aged 19-34 were enrolled in a larger intervention study on alcohol use. At baseline, participants completed measures of combat severity, PTSD symptom severity, and drinking motives to cope. At one month follow-up, participants completed measures of perceived stigma of behavioral health treatment seeking and past 30-day alcohol consequences...
November 15, 2016: Addictive Behaviors
https://www.readbyqxmd.com/read/27899474/retrospective-cohort-study-of-the-south-tyneside-exercise-referral-scheme-2009-14-predictors-of-dropout-and-barriers-to-adherence
#4
Michael C Kelly, Glen C Rae, Diane Walker, Sarah Partington, Caroline J Dodd-Reynolds, Nick Caplan
BACKGROUND: Exercise Referral Schemes (ERS) are a prevalent method of increasing physical activity levels. However, they suffer from participant dropout and research predicting dropout or barriers to adherence are limited. This study aimed to focus upon the effect of referral characteristics on dropout, dropout predictors and whether self-reported barriers to exercise predict dropout. METHODS: ERS data from 2009 to 2014 were retrieved for analysis. Chi-squared and t-tests were used to investigate differences between referral characteristics, and logistic regression used to investigate dropout predictors...
November 29, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/27898499/comt-and-bdnf-gene-variants-help-to-predict-alcohol-consumption-in-alcohol-dependent-patients
#5
Anna Klimkiewicz, Anna Mach, Andrzej Jakubczyk, Jakub Klimkiewicz, Anna Wnorowska, Maciej Kopera, Sylwia Fudalej, Margit Burmeister, Kirk Brower, Marcin Wojnar
BACKGROUND: The neurobiology of alcohol dependence (AD) involves alterations in neurotransmitters and the stress response. We hypothesized that an interaction between functional variants of dopaminergic and neurotrophic genes may influence drinking in AD. METHODS: The relationship between alcohol consumption and single-nucleotide polymorphisms, Val66Met in the brain-derived neurotrophic factor (BDNF), and Val158Met in the catechol-O-methyltransferase (COMT), was analyzed among 281 alcohol-dependent individuals...
November 24, 2016: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27898498/intention-to-drive-after-drinking-among-medical-students-contributions-of-the-protection-motivation-theory
#6
Ricardo Abrantes Amaral, André Malbergier, Danielle Ruiz Lima, Verena Castellani Vitor Santos, Clarice Gorenstein, Arthur Guerra de Andrade
OBJECTIVE: The aim of this study was to investigate whether cognitive variables proposed by the protection motivation theory (PMT) were predictive of occasional and frequent intention to drive after drinking in medical students. METHODS: One hundred fifty-five students attending preclinical years at a Medical School in São Paulo, Brazil, participated in the study. They were asked about their last month substance use, history of drinking and driving, including driving after binge drinking, and risk perceptions based on a self-report questionnaire with statements about protection motivation, threat, and coping appraisals from the PMT model...
November 24, 2016: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/27876616/protocol-for-three-parallel-multi-site-stepped-care-effectiveness-studies-for-unhealthy-alcohol-use-in-hiv-positive-patients
#7
E Jennifer Edelman, Stephen A Maisto, Nathan B Hansen, Christopher J Cutter, James Dziura, Lynn E Fiellin, Patrick G O'Connor, Roger Bedimo, Cynthia Gibert, Vincent C Marconi, David Rimland, Maria C Rodriguez-Barradas, Michael S Simberkoff, Amy C Justice, Kendall J Bryant, David A Fiellin
Unhealthy alcohol use is common among HIV-positive patients, yet effective evidence-based treatments are rarely provided in clinical settings providing HIV care. Further, given patient variability in response to initial treatments, stepped care approaches may be beneficial. We describe the rationale, aims and study design for the current StartingTreatment forEthanol inPrimary care Trials (STEP Trials); three parallel randomized controlled effectiveness trials being conducted in five Infectious Disease Clinics...
November 20, 2016: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/27875802/urgency-traits-moderate-daily-relations-between-affect-and-drinking-to-intoxication-among-young-adults
#8
Krysten W Bold, Lisa M Fucito, Kelly S DeMartini, Robert F Leeman, Henry R Kranzler, William R Corbin, Stephanie S O'Malley
BACKGROUND: Young adults with higher trait urgency (i.e., a tendency to act rashly in response to heightened affect) may be especially vulnerable to heavy drinking. The current study examined 1) the influence of urgency on daily relations between affect and drinking to intoxication, and 2) whether urgency influenced the effectiveness of naltrexone (vs. placebo) for reducing alcohol use. METHODS: This study is a secondary analysis of data from 126 (n=40 female) heavy drinking young adults, ages 18-25, enrolled in a double-blind, 8-week clinical trial comparing brief motivational intervention and either naltrexone or placebo...
November 3, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27865151/effects-of-the-benzodiazepine-gabaa-%C3%AE-1-preferring-antagonist-3-isopropoxy-%C3%AE-carboline-hydrochloride-3-isopbc-on-alcohol-seeking-and-self-administration-in-baboons
#9
August F Holtyn, V V N Phani Babu Tiruveedhula, Michael Rajesh Stephen, James M Cook, Elise M Weerts
BACKGROUND: The major inhibitory neurotransmitter, gamma-aminobutyric acid (GABA), modulates many of the behavioral effects of alcohol, including sedation, tolerance, and withdrawal. The α1 subunit of the benzodiazepine GABAA receptor is the most widely expressed alpha subunit in the brain, and has been implicated in the reinforcing- and abuse-related effects of alcohol. The aim of the present study was to examine whether treatment with a benzodiazepine GABAA α1-preferring ligand, 3-isopropoxy-β-carboline hydrochloride (3-ISOPBC), selectively decreases alcohol seeking and consumption...
November 4, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27854454/p3-event-related-potential-reactivity-to-smoking-cues-relations-with-craving-tobacco-dependence-and-alcohol-sensitivity-in-young-adult-smokers
#10
Thomas M Piasecki, Kimberly A Fleming, Constantine J Trela, Bruce D Bartholow
The current study tested whether the amplitude of the P3 event-related potential (ERP) elicited by smoking cues is (a) associated with the degree of self-reported craving reactivity, and (b) moderated by degree of tobacco dependence. Because alcohol and cigarettes are frequently used together, and given recent evidence indicating that individual differences in alcohol sensitivity influence reactivity to alcohol cues, we also investigated whether alcohol sensitivity moderated neural responses to smoking cues...
November 17, 2016: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/27842940/nalmefene-for-the-management-of-alcohol-dependence-review-on-its-pharmacology-mechanism-of-action-and-meta-analysis-on-its-clinical-efficacy
#11
Karl Mann, Lars Torup, Per Sørensen, Antoni Gual, Robert Swift, Brendan Walker, Wim van den Brink
Nalmefene, a mu- and delta-opioid receptor (MOR, DOR) antagonist and a partial kappa-opioid receptor (KOR) agonist, is approved in the European Union and other countries for the reduction of alcohol consumption in alcohol dependent patients with a high drinking risk level according to WHO ("target population"). This review presents an overview of nalmefene׳s pharmacology, its mechanisms of action and a meta-analysis on its efficacy in reducing alcohol consumption. The review was based on a systematic search of the literature...
November 11, 2016: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27836830/using-alcohol-unit-marked-glasses-enhances-capacity-to-monitor-intake-evidence-from-a-mixed-method-intervention-trial
#12
Richard de Visser, Clare Brown, Richard Cooke, Greg Cooper, Anjum Memon
AIMS: In the UK, people tend to have poor knowledge of government guidelines for alcohol use, and lack the motivation and skills required to use them to monitor their drinking. The study aim was to determine whether using glasses marked with such guidelines would improve knowledge and attitudes, increase frequency of counting units and lower alcohol intake. METHODS: A total of 450 adults in the UK participated in an intervention vs control study with 1-month follow-up...
November 10, 2016: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/27829442/emerging-adults-in-substance-misuse-intervention-preintervention-characteristics-and-responses-to-a-motivation-enhancing-program
#13
Blair Beadnell, Michele A Crisafulli, Pamela A Stafford, Erin A Casey
BACKGROUND: Emerging adulthood is an age of particularly risky behavior. Substance misuse during this phase of life can be the beginning of longer-term problems, making intervention programs particularly important. This study's purposes were to identify alcohol use profile subgroups, describe the preintervention characteristics of each, and assess how many participants transitioned to lower-risk profiles during the course of the intervention. METHODS: We used latent transition analyses to categorize 1183 people court ordered to attend Prime For Life(®) (PFL), a motivation-enhancing program, into preintervention and postintervention profiles...
November 9, 2016: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/27826731/self-generated-motives-for-not-gambling-among-young-adult-non-gamblers
#14
Christina L Rash, Daniel S McGrath
Motivational models have been shown to usefully describe reasons for engaging in addictive behaviors including gambling disorder. Although most scales designed to measure motives have been derived statistically, self-generated open-ended responses have also shown utility for identifying unique motives for gambling. While the motivational structure for gambling disorder has been extensively explored, there has been a paucity of research examining motives for choosing not to gamble. This is not the case for other addictive behaviors such as alcohol use where motives for abstaining from drinking have been well defined...
November 9, 2016: Journal of Gambling Studies
https://www.readbyqxmd.com/read/27825956/psychosocial-factors-influencing-preferences-for-food-and-nutritional-supplements-among-people-living-with-hiv-in-bangkok-thailand
#15
Santiago Rodas-Moya, Supabhorn Pengnonyang, Stephen Kodish, Saskia de Pee, Praphan Phanuphak
Malnutrition and HIV are often coincident and may lead to wasting, a strong predictor of mortality. However; ready to use therapeutic foods (RUTF) are showing promising results in restoring the nutritional status of adult people living with HIV (PLHIV) in resource constrained settings but, its acceptability seems low. This study aimed to identify the psychosocial factors influencing general preferences for food and responses to five potential nutritional supplements to guide the development of novel products to treat malnutrition among PLHIV...
November 5, 2016: Appetite
https://www.readbyqxmd.com/read/27825036/combined-treatment-for-at-risk-drinking-and-smoking-cessation-among-puerto-ricans-a-randomized-clinical-trial
#16
Virmarie Correa-Fernández, Elba C Díaz-Toro, Lorraine R Reitzel, Lin Guo, Minxing Chen, Yisheng Li, William A Calo, Ya-Chen Tina Shih, David W Wetter
Tobacco and alcohol use are linked behaviors that individually and synergistically increase the risk for negative health consequences. This study was a two-group, randomized clinical trial evaluating the efficacy of a behavioral intervention, "Motivation And Problem Solving Plus" (MAPS+), designed to concurrently address smoking cessation and the reduction of at-risk drinking. Targeted interventions may promote coaction, the likelihood that changing one behavior (smoking) increases the probability of changing another behavior (alcohol use)...
October 22, 2016: Addictive Behaviors
https://www.readbyqxmd.com/read/27824231/a-parent-based-intervention-reduces-heavy-episodic-drinking-among-first-year-college-students
#17
Joseph W LaBrie, Andrew M Earle, Sarah C Boyle, Justin F Hummer, Kevin Montes, Rob Turrisi, Lucy E Napper
A randomized controlled trial tested an interactive normative feedback-based intervention-codenamed "FITSTART"-delivered to groups of 50-100 parents of matriculating college students. The 60-min session motivated parents to alter their alcohol-related communication by correcting normative misperceptions (e.g., about how approving other parents are of student drinking) with live-generated data. Then, tips were provided on discussing drinking effectively. Incoming students (N = 331; 62.2% female) completed baseline measures prior to new-student orientation...
August 2016: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/27808555/randomized-open-label-trial-of-baclofen-for-relapse-prevention-in-alcohol-dependence
#18
Manushree Gupta, Pankaj Verma, Rajesh Rastogi, Sheetal Arora, Deeksha Elwadhi
BACKGROUND: Alcohol dependence is a progressive chronic disorder characterized by narrowing of the drinking repertoire, salience of drinking, tolerance and withdrawal phenomenon, compulsion to drink, and frequent relapses. Baclofen has been shown to promote abstinence, to reduce craving, and to reduce anxiety in alcohol-dependent individuals, and it promises to be a useful agent, although clinical data are limited at present. OBJECTIVE: The current study aimed to test the utility of baclofen, a GABA agonist, in improving the relapse rates in alcohol-dependent subjects...
November 3, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27801991/short-to-midterm-effectiveness-of-a-brief-motivational-intervention-to-reduce-alcohol-use-and-related-problems-for-alcohol-intoxicated-children-and-adolescents-in-pediatric-emergency-departments-a-randomized-controlled-trial
#19
Nicolas Arnaud, Silke Diestelkamp, Lutz Wartberg, Peter-Michael Sack, Anne Daubmann, Rainer Thomasius
OBJECTIVES: The proportion of children and adolescents receiving emergency care for acute alcohol intoxication (AAI) in Germany has sharply increased over the past years. Despite this, no randomized controlled trials (RCTs) have studied guideline- and evidence-based interventions to prevent future alcohol misuse within this population. The objective of our investigation was to evaluate the effectiveness of a brief motivational intervention (b-MI) to reduce drinking and associated problems within pediatric emergency departments (PED) in Hamburg, Germany...
November 1, 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/27796078/withdrawal-from-chronic-nicotine-exposure-produces-region-specific-tolerance-to-alcohol-stimulated-glua1-phosphorylation
#20
M Adrienne McGinn, Rod I Paulsen, Christy A Itoga, Muhammad A Farooq, Jonathan E Reppel, Kimberly N Edwards, Annie M Whitaker, Nicholas W Gilpin, Scott Edwards
BACKGROUND: Nicotine use increases alcohol drinking, suggesting that the combination of these drugs may produce synergistic effects in activating reward circuitry. Alternatively, use of either of these drugs may facilitate the development of cross-tolerance to the other to promote intake escalation. METHODS: In this study, adult male Wistar rats were chronically exposed to room air or chronic, intermittent nicotine vapor, which has been shown to produce symptoms of nicotine dependence as evidenced by elevated nicotine self-administration and a host of somatic and motivational withdrawal symptoms...
December 2016: Alcoholism, Clinical and Experimental Research
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