keyword
MENU ▼
Read by QxMD icon Read
search

Non-tuberculous mycobacteria

keyword
https://www.readbyqxmd.com/read/29134263/diminished-susceptibility-of-african-americans-to-non-tuberculous-mycobacterial-disease
#1
Jerome M Reich, Jong S Kim
The incidence of three granulomatous response diseases-sarcoidosis, tuberculosis, and non-tuberculous mycobacterial pulmonary disease-differ markedly in African-Americans versus Caucasians. In reviewing a large compendium of non-cystic-fibrosis bronchiectasis, we noted that complicating infection with non-tuberculous mycobacteria was relatively infrequent among individuals of African-American descent, confirming previous observations of their inherent resistance. Disease-specific variance among African-Americans in the efficacy of their granulomatous response suggests a nexus, a mediating, immunological mechanism...
November 13, 2017: Lung
https://www.readbyqxmd.com/read/29109708/differential-identification-of-mycobacterial-species-using-high-resolution-melting-analysis
#2
Azar D Khosravi, Mohammad Hashemzadeh, Abdolrazagh Hashemi Shahraki, Ali Teimoori
Infections caused by non-tuberculous mycobacteria (NTM) is increasing wordwide. Due to the difference in treatment of NTM infections and tuberculosis, rapid species identification of mycobacterial clinical isolates is necessary for the effective management of mycobacterial diseases treatment and their control strategy. In this study, a cost-effective technique, real-time PCR coupled with high-resolution melting (HRM) analysis, was developed for the differentiation of Mycobacterial species using a novel rpoBC sequence...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29098128/hot-tub-lung-a-diagnostic-challenge
#3
Hassaan Yasin, William E Mangano, Paras Malhotra, Ali Farooq, Hesham Mohamed
Hot tub lung (HTL) is a granulomatous lung disease thought to occur as a result of a hypersensitivity response to non-tuberculous mycobacteria (NTM). Typical radiographic findings are diffuse micronodular and/or ground glass opacities. We report an interesting case of HTL that presented with unique radiographic features, making its diagnosis a predicament. A 56-year-old immunocompetent female with chronic dyspnea and dry cough was found to have subcentimeter cavitary nodules, predominantly in the upper lung zones...
August 27, 2017: Curēus
https://www.readbyqxmd.com/read/29067624/are-guidelines-on-the-management-of-non-tuberculous-mycobacteria-lung-infections-respected-and-what-are-the-consequences-for-patients-a-french-retrospective-study-from-2007-to-2014
#4
N El-Zeenni, S Chanoine, C Recule, J-P Stahl, M Maurin, B Camara
Diagnosis and treatment of lung infections caused by non-tuberculous mycobacteria (NTM) remain challenging. Adherence of the clinicians to the American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA) 2007 guidelines is often incomplete. Between 2007 and 2014, in Grenoble Alpes University Hospital, France, 132 patients had NTM-positive cultures from lower respiratory tract (LRT) samples. We retrospectively collected diagnosis, treatment, and outcome data of patients, and evaluated the adherence of clinicians to ATS/IDSA guidelines and the consequences of patients' prognoses...
October 24, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29045552/non-tuberculous-mycobacteria-infection-following-autologous-fat-grafting-on-the-face
#5
Chih-Hao Chang, Yao-Yu Chang, Pei-Hsuan Lu
HASH(0x3b7c1d8)
October 13, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29030167/turnaround-time-of-whole-genome-sequencing-for-mycobacterial-identification-and-drug-susceptibility-testing-in-routine-practice
#6
Ioana D Olaru, Hemu Patel, Katharina Kranzer, Nelun Perera
OBJECTIVES: Until recently whole genome sequencing (WGS) for mycobacteria has been restricted mostly to the research setting. However, in 2017 Public Health England has implemented WGS for routine mycobacterial identification and susceptibility testing for Mycobacterium tuberculosis. Our objective was to evaluate the impact of this change on the laboratory turnaround times and availability of results. METHODS: Over the years 2016 and 2017, the period January 1(st) to April 30(th) was selected to represent before and after implementation of WGS...
October 10, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28990320/non-tuberculosis-mycobacterium-speciation-using-hplc-under-revised-national-tb-control-programme-rntcp-in-india
#7
George Sebastian, Sharath Burugina Nagaraja, Telagi Vishwanatha, Mamatha Voderhobli, Narayana Vijayalakshmi, Prahlad Kumar
AIMS: Non-Tuberculous Mycobacteria (NTM) are ubiquitous in nature. The data on prevalence of NTM under the RNTCP is scarce. Many NTM species have clinical significance, and hence their identification and speciation are important. METHODS AND RESULT: It is a cross-sectional study conducted at the five RNTCP accredited culture and drug susceptibility testing (CDST) laboratory. The culture isolates from AFB positive but Immunochromatographic test negative samples were taken for identification and speciation using HPLC...
October 9, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28971307/non-tuberculous-mycobacterium-bacteraemia-in-a-pregnant-systemic-lupus-erythematosus-sle-patient-a-case-review-and-pooled-case-analysis
#8
REVIEW
Syahrul Sazliyana Shaharir, Narisa Sulaiman Sahari, Zeena Mohamed Fuad, Wan Zul Haikal Wan Zukiman, Nurul Hafizah Mohd Yusof, Anita Sulong, Petrick Periasamy
Non-tuberculous mycobacteria (NTM) are recognized as an important cause of human diseases and infections. It is commonly known to cause infections of the skin, soft tissue infections, and pulmonary infection as well as bacteraemia. We report a challenging case of severe mycobacterium abscessus bacteraemia in a pregnant lady with active systemic lupus erythematous (SLE). A comprehensive literature review of NTM infection among SLE patients was also performed, and pooled analysis of the reported cases, including our case, was done to determine the clinical characteristics and factors associated with poor outcome of NTM infection...
October 3, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28967797/pulmonary-disease-by-non-tuberculous-mycobacteria-clinical-management-unmet-needs-and-future-perspectives
#9
Lars-Olof Larsson, Eva Polverino, Wouter Hoefsloot, Luigi R Codecasa, Roland Diel, Stephen G Jenkins, Michael R Loebinger
The number of patients with pulmonary disease caused by non-tuberculous mycobacteria (NTM) is increasing globally. Poor resistance against infections, for example, due to pre-existing lung diseases, immune deficiency and immune-modulating treatment, predisposes the population to developing pulmonary NTM disease. The incidence of pre-existing lung diseases such as chronic obstructive pulmonary disease and bronchiectasis has also increased. NTM disease diagnosis is often delayed due to non-specific symptoms. The therapeutic arsenal is limited and adherence to treatment guidelines is often low since the treatment regimens are complex, lengthy and side effects are common...
October 10, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28961864/biological-evaluation-of-diphenyleneiodonium-chloride-dpic-as-a-potential-drug-candidate-for-treatment-of-non-tuberculous-mycobacterial-infections
#10
Alok Kumar Singh, Ritesh Thakare, Pratiksha Karaulia, Swetarka Das, Isha Soni, Manitosh Pandey, Amit Kumar Pandey, Sidharth Chopra, Arunava Dasgupta
Background: Novel drug discovery against non-tuberculous mycobacteria is beset with a large number of challenges including the existence of myriad innate drug resistance mechanisms as well as a lack of suitable animal models, which hinders effective translation. In order to identify molecules acting via novel mechanisms of action, we screened the Library of Pharmacologically Active Compounds against non-tuberculous mycobacteria to identify such compounds. Methods: Whole-cell growth inhibition assays were used to screen and identify novel inhibitors...
November 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28957340/body-habitus-in-patients-with-and-without-bronchiectasis-and-non-tuberculous-mycobacteria
#11
Michael D Schweitzer, Oriana Salamo, Michael Campos, Dean E Schraufnagel, Ruxana Sadikot, Mehdi Mirsaeidi
BACKGROUND: Female gender, tall stature, presence of bronchiectasis are associated with pulmonary nontuberculous mycobacterial (NTM) infections. The biologic relationship between the body habitus and NTM infection is not well defined and the body habitus profile of the patients with NTM and concurrent bronchiectasis is completely unknown. METHODS: We conducted a case control study at the Miami VA Healthcare System and the University of Illinois Medical Center on patients with pulmonary NTM infections between 2010 and 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28955087/mycobacterium-abscessus-lymphadenitis-in-bone-marrow-transplant-patient
#12
Muhammad Khalid, Syed Asad Ali
Non-tuberculous mycobacteria (NTM) are acid-fast bacteria categorized into rapidly growing and slow growing mycobacteria. NTM are more common in transplant patients who are immunocompromised. Here we report the case of a post- bone marrow transplant adolescent male presenting with submandibular swelling and fever. The gland was excised and the histopathology showed chronic granulomatous inflammation. Culture grew Mycobacterium abscessus which was sensitive to amikacin, linezolid and clarithromycin. A good response was achieved on therapy...
October 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28943571/mycobacterium-wolinskyi-peritonitis-after-peritoneal-catheter-embedment-surgery
#13
Hiroyuki Fujikura, Kei Kasahara, Yoshihiko Ogawa, Nobuyasu Hirai, Seiya Yoshii, Shingo Yoshihara, Taku Ogawa, Shinsuke Yonekawa, Natsuko Imakita, Yuichi Nishioka, Tatsuo Yoneda, Katsunori Yoshida, Ken-Ichi Samejima, Kaori Tanabe, Yoshihiko Saito, Hisakazu Yano, Keiichi Mikasa
Mycobacterium wolinskyi belongs to the Mycobacterium smegmatis group, which comprises rapidly growing non-tuberculous mycobacteria. The number of case reports on M. wolinskyi infections associated with postoperative wounds has increased in recent years. We herein report a case of peritonitis due to M. wolinskyi after peritoneal catheter embedment surgery. Identification was achieved based on 16S ribosomal RNA and rpoB gene sequencing of the isolate. The patient recovered following catheter removal and treatment with levofloxacin and minocycline for one month...
September 25, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28931915/non-tuberculous-mycobacteria-isolated-from-pulmonary-samples-in-sub-saharan-africa-a-systematic-review-and-meta-analyses
#14
Catherine Okoi, Suzanne T B Anderson, Martin Antonio, Sarah N Mulwa, Florian Gehre, Ifedayo M O Adetifa
Pulmonary non-tuberculous mycobacterial (NTM) disease epidemiology in sub-Saharan Africa is not as well described as for pulmonary tuberculosis. Earlier reviews of global NTM epidemiology only included subject-level data from one sub-Saharan Africa country. We systematically reviewed the literature and searched PubMed, Embase, Popline, OVID and Africa Wide Information for articles on prevalence and clinical relevance of NTM detection in pulmonary samples in sub-Saharan Africa. We applied the American Thoracic Society/Infectious Disease Society of America criteria to differentiate between colonisation and disease...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28924121/pleuritis-caused-by-mycobacterium-kyorinense-without-pulmonary-involvement
#15
Tatsuyoshi Ikeue, Hiroshi Yoshida, Eiichiro Tanaka, Issei Ohi, Susumu Noguchi, Akari Fukao, Satoshi Terashita, Sadao Horikawa, Takakazu Sugita
We herein describe the first known case of pleuritis caused by Mycobacterium kyorinense without pulmonary involvement. A 48-year-old man undergoing immunosuppressant therapy presented with cough and dyspnea. An accumulation of pleural fluid was noted; however, computed tomography revealed no pulmonary lesions. Cultures of the fluid yielded non-tuberculous mycobacteria, which was identified as Mycobacterium kyorinense. The patient recovered after 6 months of therapy with clarithromycin and moxifloxacin. Clinicians should be aware that Mycobacterium kyorinense can cause pleuritis without pulmonary involvement...
October 15, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28919618/molecular-detection-and-differentiation-of-mycobacterium-tuberculosis-complex-and-non-tuberculous-mycobacterium-in-the-clinical-specimens-by-real-time-pcr
#16
M M Rahman, M R Rahim, A Khaled, T A Nasir, F Nasrin, M A Hasan
Mycobacteria are subdivided into three groups: the Mycobacterium tuberculosis complex, the non-tuberculous mycobacteria called NTM or MOTT (Mycobacteria Other Than Tuberculosis) and Mycobacterium leprae. Over the past few decades, the incidence of infections caused by NTM has increased world wide. The differentiation of Mycobacterium tuberculosis complex from NTM is of primary importance for infection control and choice of antimicrobial therapy. However, there is so far no report in Bangladesh about the detection of NTM and hence differentiation of MTB and NTM...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28911363/bronchial-angles-are-associated-with-nodular-bronchiectatic-non-tuberculous-mycobacteria-lung-disease
#17
T Lee, J Y Park, H Y Lee, H-J Lim, J S Park, Y-J Cho, T J Kim, K W Lee, J H Lee, C-T Lee, H I Yoon
BACKGROUND: The nodular bronchiectatic (NB) form of non-tuberculous mycobacteria (NTM) lung disease usually involves the right middle lobe (RML) and the left upper lobe lingular segment. However, the reason underlying this preference is not known. METHODS: Fifty patients with NB NTM lung disease who had both positive NTM culture(s) and NB lesions in the RML or lingular segment on computed tomography (CT) of the chest, and 100 healthy subjects matched for sex, age, height and body weight with normal chest CT, were randomly selected...
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28886145/application-of-a-whole-blood-mycobacterial-growth-inhibition-assay-to-study-immunity-against-mycobacterium-tuberculosis-in-a-high-tuberculosis-burden-population
#18
Richard Baguma, Adam Penn-Nicholson, Erica Smit, Mzwandile Erasmus, Jonathan Day, Lebohang Makhethe, Marwou de Kock, E Jane Hughes, Michele van Rooyen, Bernadette Pienaar, Lynnett Stone, Willem Hanekom, Michael J Brennan, Robert S Wallis, Mark Hatherill, Thomas J Scriba
The determinants of immunological protection against Mycobacterium tuberculosis (M.tb) infection in humans are not known. Mycobacterial growth inhibition assays have potential utility as in vitro surrogates of in vivo immunological control of M.tb. We evaluated a whole blood growth inhibition assay in a setting with high burden of TB and aimed to identify immune responses that correlate with control of mycobacterial growth. We hypothesized that individuals with underlying M.tb infection will exhibit greater M...
2017: PloS One
https://www.readbyqxmd.com/read/28879160/performance-of-xpert-%C3%A2-mtb-rif-among-tuberculosis-outpatients-in-lilongwe-malawi
#19
Tarsizio Chikaonda, Nelson Nguluwe, Brian Barnett, Runa H Gokhale, Robert Krysiak, Isaac Thengolose, Nora E Rosenberg, Christopher Stanley, James Mpunga, Irving F Hoffman, Mina Hosseinipour, Lesley Scott, Wendy Stevens
BACKGROUND: Xpert(®) MTB/RIF is a molecular test for the detection of Mycobacterium tuberculosis and rifampicin resistance. It is considered to be a great advance over smear microscopy and culture. However, there is very little information regarding the performance characteristics of Xpert MTB/RIF in Malawi. OBJECTIVE: We aimed to evaluate the performance of Xpert MTB/RIF in a Malawian setting. METHODS: Stored sputum pellets were processed on Xpert MTB/RIF between June 2012 and May 2014...
2017: African Journal of Laboratory Medicine
https://www.readbyqxmd.com/read/28879157/evaluation-of-the-sd-bioline-tb-ag-mpt64-test-for-identification-of-mycobacterium-tuberculosis-complex-from-liquid-cultures-in-southwestern-uganda
#20
Patrick Orikiriza, Dan Nyehangane, Daniel Atwine, John J Kisakye, Kennedy Kassaza, Juliet-Mwanga Amumpaire, Yap Boum
BACKGROUND: To confirm presence of Mycobacterium tuberculosis complex, some tuberculosis culture laboratories still rely on para-nitrobenzoic acid (PNB), a traditional technique that requires sub-culturing of clinical isolates and two to three weeks to give results. Rapid identification tests have improved turnaround times for mycobacterial culture results. Considering the challenges of the PNB method, we assessed the performance of the SD Bioline TB Ag MPT64 assay by using PNB as gold standard to detect M...
2017: African Journal of Laboratory Medicine
keyword
keyword
2832
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"