keyword
MENU ▼
Read by QxMD icon Read
search

Vitiligo treatment

keyword
https://www.readbyqxmd.com/read/28925103/autoimmune-diseases-involving-skin-and-intestinal-mucosa-are-more-frequent-in-adolescents-and-young-adults-suffering-from-atopic-dermatitis
#1
REVIEW
Francesca Cipriani, Alice Marzatico, Giampaolo Ricci
Evidence has emerged about the relationship between atopic dermatitis (AD) and autoimmune diseases, but the underlying mechanism of this association is complex and still unclear. Recent epidemiological data from the published work suggest a positive correlation. The aim of this review is to analyze the frequency of co-occurrence of AD and autoimmune diseases. Our systematic review included 22 articles from PubMed describing the reciprocal association between AD and autoimmune diseases. Although not all the studies achieved statistically significant results, patients suffering from autoimmune diseases involving skin and intestinal mucosa, such as vitiligo, alopecia areata, celiac disease and inflammatory bowel diseases, showed a higher risk to have AD as comorbidity...
September 19, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28906087/phototherapy-for-vitiligo-what-s-new
#2
Andrea Paro Vidolin, Caterina Aurizi, Giovanni Leone
Vitiligo is a disorder characterized by the development of depigmented macules and patches. Existing treatments include topical and systemic immunosuppressants, topical vitamin D analogues in monotherapy or in association with phototherapy, phototherapy and surgical techniques, which together may serve to halt disease progression, stabilize depigmented lesions, and encourage repigmentation. Narrow-band UVB (NB-UVB 310-315 nm) radiation is now considered as the "gold standard" for the treatment of diffuse vitiligo...
October 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28904532/the-use-of-adipose-derived-stem-cells-in-selected-skin-diseases-vitiligo-alopecia-and-nonhealing-wounds
#3
REVIEW
Agnieszka Owczarczyk-Saczonek, Anna Wociór, Waldemar Placek, Wojciech Maksymowicz, Joanna Wojtkiewicz
The promising results derived from the use of adipose-derived stem cells (ADSCs) in many diseases are a subject of observation in preclinical studies. ADSCs seem to be the ideal cell population for the use in regenerative medicine due to their easy isolation, nonimmunogenic properties, multipotential nature, possibilities for differentiation into various cell lines, and potential for angiogenesis. This article reviews the current data on the use of ADSCs in the treatment of vitiligo, various types of hair loss, and the healing of chronic wounds...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28894436/serum-thyroid-hormone-antibodies-are-frequent-in-patients-with-polyglandular-autoimmune-syndrome-type-3-particularly-in-those-who-require-thyroxine-treatment
#4
Roberto Vita, Maria Giulia Santaguida, Camilla Virili, Maria Segni, Marina Galletti, Mattia Mandolfino, Flavia Di Bari, Marco Centanni, Salvatore Benvenga
Polyglandular autoimmune syndrome (PAS) type 3 consists of autoimmune thyroid disease (AITD) coexisting with ≥1 non-thyroidal autoimmune disease (NTAID) other than Addison's disease and hypoparathyroidism. We evaluated the prevalence and repertoire of thyroid hormones antibodies (THAb) in PAS-3 patients. Using a radioimmunoprecipation technique, we measured THAb (T3IgM, T3IgG, T4IgM, and T4IgG) in 107 PAS-3 patients and 88 controls (patients with AITD without any NTAID). Based on the selective coexistence of AITD with one NTAID (chronic autoimmune gastritis, non-segmental vitiligo or celiac disease), patients were divided into group 1 (chronic autoimmune gastritis positive, n = 64), group 2 (non-segmental vitiligo positive, n = 24), and group 3 (celiac disease positive, n = 15)...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28881630/protective-effect-of-madecassoside-on-h2o2-induced-oxidative-stress-and-autophagy-activation-in-human-melanocytes
#5
Yuting Ling, Qingli Gong, Xixi Xiong, Li Sun, Wene Zhao, Wenyuan Zhu, Yan Lu
BACKGROUND: Centella asiatica (L.) Urb. is a traditional Chinese medicine that has many medical applications, including wound healing and anti-oxidation. Some traditional Chinese Medicine doctors have found that it has therapeutic effects for external use in the repigmentation of vitiligo and post-inflammatory hypopigmentation. This study was designed to evaluate the effects of madecassoside, a major bioactive component of C. asiatica, on oxidative stress in human melanocytes and its possible mechanism of action...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28836394/reduced-nrf2-activation-in-pi3k-phosphorylation-impaired-vitiliginous-keratinocytes-increases-susceptibility-to-ros-generating-chemical-induced-apoptosis
#6
Hyangmi Kim, Chang Seo Park, Ai-Young Lee
Keratinocytes in affected epidermis of vitiligo patients are known to have impaired activation of the PI3K/AKT pathway. Based on critical roles of keratinocytes and oxidative stress in vitiligo development, this study examined whether keratinocytes with impaired PI3K activation were more vulnerable to apoptosis caused by oxidative stress from phenolic compounds, p-tert-butylphenol (4-TBP) and hydroquinone (HQ). Cell viability assay, FACS analysis, ELISA for TNF-α or IL-1a, ROS assay, Western blot analysis for Nrf2 expression, and confocal microscopy with anti-Nrf2 and phospho-PI3K antibodies were done on primary cultured normal human keratinocytes with or without PI3K knockdown in the presence or absence of chemical treatment or antioxidant...
August 24, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28834191/combined-treatment-with-fractional-carbon-dioxide-laser-autologous-platelet-rich-plasma-and-narrow-band-ultraviolet-b-for-vitiligo-in-different-body-sites-a-prospective-randomized-comparative-trial
#7
Rania Abdelghani, Naglaa A Ahmed, Hanan M Darwish
BACKGROUND: Multiple treatment options are introduced in treatment of vitiligo but the response is unsatisfactory. OBJECTIVE: In this prospective, randomized, comparative trial, we studied the effect of combined treatment with fractional carbon dioxide (CO2 ) laser, platelet-rich plasma (PRP) injection, and narrowband ultraviolet B (NB-UVB) for stable nonsegmental vitiligo regarding repigmentation grade, patient's satisfaction, and side effects. METHODS: Eighty adult patients with localized nonsegmental vitiligo were enrolled in this study...
August 20, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28761302/reactivation-of-herpes-simplex-virus-secondary-to-excimer-laser-treatment-in-a-patient-with-vitiligo
#8
Yu Seok Jung, Ji Hae Lee, Gyong Moon Kim, Jung Min Bae
No abstract text is available yet for this article.
August 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28753523/development-and-in-vitro-assessment-of-psoralen-and-resveratrol-co-loaded-ultradeformable-liposomes-for-the-treatment-of-vitiligo
#9
Sindhu Doppalapudi, Shaheen Mahira, Wahid Khan
Vitiligo is a de-pigmenting skin disorder characterized by white patches on skin due to partial or complete loss of melanocytes. Psoralen in combination with ultraviolet-A (PUVA) acts by stimulation of melanin content and tyrosinase activity in melanocytes. Resveratrol, a sirtuin activator and a potential anti-oxidant reduce oxidative stress which is one of the triggering factors for initiation of vitiligo. Despite their therapeutic activity, weak percutaneous permeability of psoralen and poor solubility of resveratrol hinders their effective topical administration...
July 12, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28748302/effect-of-combination-of-fractional-co2-laser-and-narrow-band-ultraviolet-b-versus-narrow-band-ultraviolet-b-in-the-treatment-of-non-segmental-vitiligo
#10
Mohamed Bakr El-Zawahry, Naglaa Sameh Zaki, Marian Youssry Wissa, Marwah Adly Saleh
The present study was designed to evaluate the effect of combining fractional CO2 laser with narrow-band ultraviolet B (NB-UVB) versus NB-UVB in the treatment of non-segmental vitiligo. The study included 20 patients with non-segmental stable vitiligo. They were divided into two groups. Group I received a single session of fractional CO2 laser therapy on the right side of the body followed by NB-UVB phototherapy twice per week for 8 weeks. Group II received a second session of fractional CO2 laser therapy after 4 weeks from starting treatment with NB-UVB...
July 26, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28724115/the-efficacy-of-a-gain-switched-311-nm-titanium-sapphire-laser-in-the-treatment-of-vitiligo-a-pilot-study-of-14-patients
#11
Jung Min Bae, Ji Hae Lee, Yu Seok Jung, Gyong Moon Kim
No abstract text is available yet for this article.
July 19, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28722334/potential-emerging-treatment-in-vitiligo-using-er-yag-in-combination-with-5fu-and-clobetasol
#12
Fatemeh Mokhtari, Anis Bostakian, Zabihollah Shahmoradi, Tohid Jafari-Koshki, Fariba Iraji, Gita Faghihi, Sayed Mohsen Hosseini, Behzad Bafandeh
BACKGROUND: Vitiligo is a pigmentary disorder of skin affecting at least 1% of the world population of all races in both sexes. Its importance is mainly due to subsequent social and psychological problems rather than clinical complications. Various treatment choices are available for vitiligo; however, laser-based courses have shown to give more acceptable results. OBJECTIVE: The aim of this trial was to evaluate the efficacy of Er:YAG laser as a supplementary medicine to topical 5FU and clobetasol in vitiligo patients...
July 19, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28718676/selenium-zinc-copper-cu-zn-ratio-and-total-antioxidant-status-in-the-serum-of-vitiligo-patients-treated-by-narrow-band-ultraviolet-b-phototherapy
#13
Marta Wacewicz, Katarzyna Socha, Jolanta Soroczyńska, Marek Niczyporuk, Piotr Aleksiejczuk, Jolanta Ostrowska, Maria H Borawska
BACKGROUND: Vitiligo is a chronic, depigmenting skin disorder, whose pathogenesis is still unknown. Narrow band ultraviolet-B (NB-UVB) is now one of the most widely used treatment of vitiligo. It was suggested that trace elements may play a role in pathogenesis of vitiligo. AIM: The aim of this study was to estimate the concentration of selenium (Se), zinc (Zn), copper (Cu) and Cu/Zn ratio as well as total antioxidant status (TAS) in the serum of patients with vitiligo...
August 1, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28710660/fractional-er-yag-laser-assisting-topical-betamethasone-solution-in-combination-with-nb-uvb-for-resistant-non-segmental-vitiligo
#14
Ru Yan, Jinping Yuan, Hongqiang Chen, Yuan-Hong Li, Yan Wu, Xing-Hua Gao, Hong-Duo Chen
Resistant non-segmental vitiligo is difficult to be treated. Ablative erbium-YAG (Er:YAG) laser has been used in the treatment of vitiligo, but the ablation of entire epidermis frustrated the compliance of patients. The purpose of this study is to investigate the effects of fractional Er:YAG laser followed by topical betamethasone and narrow band ultraviolet B (NB-UVB) therapy in the treatment of resistant non-segmental vitiligo. The vitiligo lesions of each enrolled patient were divided into four treatment parts, which were all irradiated with NB-UVB...
July 14, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28708646/modified-technique-of-cultured-epithelial-cells-transplantation-on-facial-segmental-vitiligo
#15
Ke-Jia Wu, Lu-Yan Tang, Jian Li, Shu-Jun Chen, Jin-Ran Lin, Qin-Yuan Zhu, Wen-Wen Fu, Jin-Hua Xu, Wen-Yu Wu
BACKGROUND: Cultured epithelial cells transplantation is a known surgical technique for vitiligo. OBJECTIVE: To evaluate the factors influencing efficacy and safety of cultured epithelial cells transplantation in 9-month follow-up. METHODS: Demographic, clinical, and repigmentation outcomes were reviewed for patients with facial segmental vitiligo who had undergone cultured epithelial cells transplantation from November 2013 to July 2015 at the clinic of the Department of Dermatology, Huashan Hospital, China...
September 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28700789/hair-repigmentation-during-immunotherapy-treatment-with-an-anti-programmed-cell-death-1-and-anti-programmed-cell-death-ligand-1-agent-for-lung-cancer
#16
Noelia Rivera, Aram Boada, M Isabel Bielsa, M Teresa Fernández-Figueras, Enric Carcereny, M Teresa Moran, Carlos Ferrándiz
Importance: New targeted therapies for cancer have been released in recent years, opening new horizons in the treatment of patients with cancer. However, their related adverse events (AE) are not fully characterized. Hair repigmentation (HR) is a nondescribed effect secondary to anti-programmed cell death 1 (anti-PD-1) and anti-programmed cell death ligand 1 (anti-PD-L1 ) therapy for treatment of lung cancer (LC), in opposition to the vitiligo reactions that develop during melanoma treatment...
July 12, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28697225/low-dose-methotrexate-for-vitiligo
#17
Anna Cristina Garza-Mayers, Daniela Kroshinsky
<p>BACKGROUND: Treatment of vitiligo is aimed at repigmentation and often consists of multiple modalities, none of which are universally or rapidly successful. Extensive cases are most often treated with ultraviolet light therapy, which can be both costly and time-consuming. Though vitiligo is an autoimmune disease, there is no current data to support systemic immunosuppressive monotherapy.</p> <p>CASE SUMMARY: Here we present a case series of 3 patients with vitiligo treated for 11-16 months with low-dose methotrexate (12...
July 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28691067/mimicking-melanosomes-polydopamine-nanoparticles-as-artificial-microparasols
#18
Yuran Huang, Yiwen Li, Ziying Hu, Xiujun Yue, Maria T Proetto, Ying Jones, Nathan C Gianneschi
A primary role of melanin in skin is the prevention of UV-induced nuclear DNA damage to human skin cells, where it serves to screen out harmful UV radiation. Melanin is delivered to keratinocytes in the skin after being excreted as melanosomes from melanocytes. Defects in melanin production in humans can cause diseases, many of which currently lack effective treatments due to their genetic origins (e.g., skin cancer, vitiligo, and albinism). The widespread prevalence of melanin-related diseases and an increasing interest in the performance of various polymeric materials related to melanin necessitates novel synthetic routes for preparing melanin-like materials...
June 28, 2017: ACS Central Science
https://www.readbyqxmd.com/read/28689294/cerebellar-disease-associated-with-anti-glutamic-acid-decarboxylase-antibodies-review
#19
REVIEW
José Fidel Baizabal-Carvallo, Marlene Alonso-Juarez
Several neurological syndromes have been recognized associated to GAD antibodies. Among those disorders, cerebellar ataxia (CA) is one of the most common, along with stiff-person syndrome. Patients with GAD associated CA present with a progressive pancerebellar syndrome, with a subacute or chronic evolution, along with other neurological manifestations such as stiffness, oculomotor dysfunction, epilepsy, and cognitive dysfunction. These symptoms may be preceded by the so-called "brainstem attacks", where manifestations consistent with transient dysfunction of the brainstem may be observed...
July 8, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28685247/vitiligo-focus-on-clinical-aspects-immunopathogenesis-and-therapy
#20
REVIEW
Katia Boniface, Julien Seneschal, Mauro Picardo, Alain Taïeb
Vitiligo is an acquired chronic depigmenting disorder of the skin, with an estimated prevalence of 0.5% of the general population, characterized by the development of white macules resulting from a loss of epidermal melanocytes. The nomenclature has been revised after an extensive international work within the vitiligo global issues consensus conference, and vitiligo (formerly non-segmental vitiligo) is now a consensus umbrella term for all forms of generalized vitiligo. Two other subsets of vitiligo are segmental vitiligo and unclassified/undetermined vitiligo, which corresponds to focal disease and rare variants...
July 6, 2017: Clinical Reviews in Allergy & Immunology
keyword
keyword
28314
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"