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https://www.readbyqxmd.com/read/28749618/radiation-induced-second-cancer-risk-from-external-beam-photon-radiotherapy-for-head-and-neck-cancer-impact-on-in-field-and-out-of-field-organs
#1
Vasanthan Sakthivel, Ganesh Kadirampatti Mani, Sunil Mani, Raghavendiran Boopathy
The purpose of this paper is to provide data on development of second primary cancers within or adjacent to tissue irradiated in the treatment of primary head and neck cancers using different techniques and modalities. Materials and methods: We selected five patients with HandN tumors located in base of the tongue for risk assessment. In order to examine the impact of choices of various planning techniques, numbers of beams and beam energy used in treatment plans - 7 and 9 field Intensity modulated radiotherapy (IMRT) plans using 6MV and 10 MV beam energies and a 6MV Volumetric modulated arc therapy (VMAT) plans were planned...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28749282/oronasal-squamous-cell-carcinomas-in-fran%C3%A3-ois-langurs-trachypithecus-francoisi
#2
John A Flanders, Michelle E Thompson, Mitzi J Palazzolo, Michael M Garner, Matthew Reed, Donna M Ialeggio, Matti Kiupel, William H Westra, Kathryn C Gamble
Squamous cell carcinomas (SCCs) are common oronasal tumors in nonhuman primates. In this study, 11 cases of oronasal SCC in François' langurs ( Trachypithecus francoisi ) are described. Five initial cases were discovered on review of the North American François' langur studbook, with a potential familial pattern observed. The studbook was used to identify related individuals, and records were requested for review. Six additional cases were documented, and samples from all cases were submitted for microscopic review, as well as polymerase chain reaction (PCR), immunohistochemistry (IHC), and in situ hybridization (ISH), for generic papillomaviruses and PCR for herpesviruses because either virus may cause SCC in humans and other nonhuman primates...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749266/epidemiologic-evaluation-of-elephant-endotheliotropic-herpesvirus-3b-infection-in-an-african-elephant-loxodonta-africana
#3
Ellen Bronson, Michael McClure, Jennifer Sohl, Ellen Wiedner, Sherry Cox, Erin M Latimer, Virginia R Pearson, Gary S Hayward, Angela Fuery, Paul D Ling
This epidemiologic study follows a 5-yr-old male African elephant ( Loxodonta africana ) during an episode of hemorrhagic disease (HD) due to elephant endotheliotropic herpesvirus 3B (EEHV3B) utilizing data from complete blood counts, electrophoresis and acute phase protein analysis, and polymerase chain reaction (PCR) of multiple body fluids during and after the clinical episode. The elephant presented with sudden onset of marked lethargy and inappetence followed by hypersalivation, hyperemia of the conjunctivae and focally on the tongue, and swellings on the head and ventrum...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28748261/long-term-functional-outcomes-after-resection-of-tongue-cancer-determining-the-optimal-reconstruction-method
#4
Yong Bae Ji, Yong Hee Cho, Chang Myeon Song, Youn Hwan Kim, Jeong Tae Kim, Hee Chang Ahn, Kyung Tae
The appropriate tongue reconstruction method is critical for better functional outcomes. The aim of this study was to determine the optimal reconstructive method for restoring postoperative function based on the extent of resection. We retrospectively reviewed 43 patients with lateral oral tongue cancer who underwent glossectomy between January 2010 and October 2014. Tongue mobility, articulation, verbal diadochokinesis, speech intelligibility and swallowing outcomes were assessed 2-3 years postoperative and were analyzed according to resected tongue volume and the method of reconstruction...
July 26, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28747140/mitochondrial-assembly-receptor-expression-is-an-independent-prognosticator-for-patients-with-oral-tongue-squamous-cell-carcinoma
#5
Yan-Ye Su, Chang-Han Chen, Chih-Yen Chien, Wei-Che Lin, Wan-Ting Huang, Shau-Hsuan Li
INTRODUCTION: Recent evidence suggests that the local renin-angiotensin system has been implicated in various malignancies. The mitochondrial assembly receptor is a newly identified receptor for angiotensin peptides, angiotensin-(1-7), and has an important role in the renin-angiotensin system. However, the role of the mitochondrial assembly receptor in the prognosis of cancer patients remains unclear. The aim of this study was to evaluate the significance of mitochondrial assembly receptor signaling in the prognosis of oral tongue squamous cell carcinoma...
July 2017: Journal of the Renin-angiotensin-aldosterone System: JRAAS
https://www.readbyqxmd.com/read/28746560/developing-and-validating-the-perioperative-thirst-discomfort-scale
#6
Pamela Rafaela Martins, Lígia Fahl Fonseca, Edilaine Giovanini Rossetto
OBJECTIVE: Developing and validating a scale to assess perioperative thirst discomfort. METHOD: A methodological research conducted in 2014 and 2015 at the surgical center of a public hospital in the north of Paraná, Brazil. The scale was developed after literature review, followed by face and content validation, and reliability assessment through its internal consistency and inter-observer equivalence. RESULTS: Seven items make up the scale: dry mouth; dry lips; thick tongue; thick saliva; dry throat, bad taste and desire to drink water...
July 20, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28746528/simple-motor-tasks-independently-predict-extubation-failure-in-critically-ill-neurological-patients
#7
Fernanda Machado Kutchak, Marcelo de Mello Rieder, Josué Almeida Victorino, Carla Meneguzzi, Karla Poersch, Luiz Alberto Forgiarini, Marino Muxfeldt Bianchin
Objective: To evaluate the usefulness of simple motor tasks such as hand grasping and tongue protrusion as predictors of extubation failure in critically ill neurological patients. Methods: This was a prospective cohort study conducted in the neurological ICU of a tertiary care hospital in the city of Porto Alegre, Brazil. Adult patients who had been intubated for neurological reasons and were eligible for weaning were included in the study. The ability of patients to perform simple motor tasks such as hand grasping and tongue protrusion was evaluated as a predictor of extubation failure...
May 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28746465/orofacial-characteristics-of-functionally-independent-elders
#8
Danielle Nunes Moura Silva, Erica de Araújo Brandão Couto, Helena Maria Gonçalves Becker, Maria Aparecida Camargos Bicalho
Purpose: to understand the main orofacial characteristics of functionally independent elderly individuals and to investigate their association with age, gender, socioeconomic level, and dental status. Methods: an observational, cross-sectional, and analytical study was carried out with a non-probabilistic sample. Inclusion criteria: minimum age of 60 years, individual in good health conditions according to a pre-established protocol published by the health care service...
July 20, 2017: CoDAS
https://www.readbyqxmd.com/read/28745929/molecular-and-cellular-mechanisms-of-palate-development
#9
C Li, Y Lan, R Jiang
Development of the mammalian secondary palate involves highly dynamic morphogenetic processes, including outgrowth of palatal shelves from the oral side of the embryonic maxillary prominences, elevation of the initially vertically oriented palatal shelves to the horizontal position above the embryonic tongue, and subsequently adhesion and fusion of the paired palatal shelves at the midline to separate the oral cavity from the nasal cavity. Perturbation of any of these processes could cause cleft palate, a common birth defect that significantly affects patients' quality of life even after surgical treatment...
April 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28745413/a-simple-optoelectronic-tongue-discriminates-amino-acids
#10
Uwe Heiko Bunz, Benhua Wang, Jinsong Han, Chao Ma, Markus Bender, Kai Seehafer, Andreas Herrmann
A self-assembled nine-element optoelectronic tongue consisting of a po¬sitively charged water soluble poly(para-phenyleneethynylene) and three metal ions (Fe2+, Co2+ and Cu2+) at three different pH-values (pH 7, 10 and 13) discriminates all of the 20 natural amino acids in water. Unknown identification was not ideal. Addition of a highly positively charged green fluorescent protein in the presence of Fe2+, Co2+ and Cu2+ increased the unknown identification to above 86%. Li¬near discriminant analysis (LDA) orders the responses ac¬cording to the amino acid type, i...
July 26, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28744898/effect-of-chewing-or-compressing-food-on-autonomic-nervous-activity-in-older-adults
#11
Midori Ohta, Takayuki Ueda, Kaoru Sakurai
OBJECTIVE: To determine if autonomic nervous activity increases in older people during mastication and how this activity is related to the softness of food. We hypothesised that the coefficient of variation of R-R intervals (CVRR), high-frequency (HF) power, low-frequency (LF) power, LF/HF ratio and total power increase during chewing foods within the range of softness from moderate food to extremely soft food in older adults. MATERIALS AND METHODS: Participants were 20 older volunteers (71-90 year old)...
July 26, 2017: Gerodontology
https://www.readbyqxmd.com/read/28744047/effects-of-lingual-strength-training-on-lingual-strength-and-articulator-function-in-stroke-patients-with-dysarthria
#12
Jong Hoon Moon, Deok Gi Hong, Kye Ho Kim, Yo An Park, Suk-Chan Hahm, Sung-Jin Kim, Young Sik Won, Hwi-Young Cho
[Purpose] This study investigated the effects of lingual strength training (LST) on lingual strength and articulator function in stroke patients with dysarthria. [Subjects and Methods] 16 stroke patients with dysarthria were randomly assigned into two groups: the experimental group (n=8) or the control group (n=8). Both groups received the conventional rehabilitation therapy at 30 min/day, 5 times for week, and during 4 weeks, and the experimental group received an additional 30 min of LST using the Iowa Oral Performance Instrument (IOPI)...
July 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28742994/unusual-case-of-a-massive-macroglossia-secondary-to-myxedema-a-case-report-and-literature-review
#13
James C Melville, Kelsey D Menegotto, Timothy C Woernley, Blake D Maida, Ibrahim Alava
Macroglossia is classified as true macroglossia, which exhibits abnormal histology with clinical findings, and relative macroglossia, in which normal histology does not correlate with pathologic enlargement. This report describes an atypical case of morbidity with massive macroglossia secondary to myxedema; the macroglossia enlarged over a 3-month period before being presented to the Department of Oral and Maxillofacial Surgery, University of Texas Health Sciences Center at Houston (Houston, TX). Substantial enlargement of the tongue (16 cm long × 10 cm wide) was first attributed to angioedema, which was refractory to the discontinuation of lisinopril and a C1 esterase inhibitor...
June 30, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28742057/effect-of-photodynamic-therapy-in-the-reduction-of-halitosis-in-patients-with-multiple-sclerosis-clinical-trial
#14
Marcela Leticia Leal Gonçalves, Sandra Kalil Bussadori, Yara Dadalti Fragoso, Vinícius Vieira Belarmino da Silva, Alessandro M Deana, Ana Carolina Ciarcia, Erika Horácio Pinto, Anna Carolina Ratto Tempestini Horliana, Cristiane Miranda França
Smell and odours play a vital role in social interaction. Halitosis is a social problem that affects one-third of the population causing a negative impact in the quality of life. There is little knowledge on the prevalence and management of halitosis in Multiple Sclerosis (MS) patients. The present study aimed to evaluate the presence of halitosis in patients with MS when compared to a control group and the treatment with antimicrobial photodynamic therapy (aPDT) against halitosis. This is a case-control clinical study where 60 patients were evaluated: 30 MS patients in treatment at the Specialties Clinic School of Medicine, and 30 healthy patients, matched in age and gender, for the control group...
July 25, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28741231/large-cell-transformation-of-oral-mycosis-fungoides
#15
Ahmed S Sultan, Behzad Mostoufi, John C Papadimitriou, Rima Koka, John Basile, Rania H Younis
Mycosis fungoides (MF) accounts for approximately 50% of all primary cutaneous lymphomas. MF occurrence in the oral cavity is extremely rare with approximately 45 cases reported to date. We present a case of a 68 year-old man with a raised nodular lesion of the ventral tongue with clinical impression of irritational fibroma. Histopathologic and immunohistochemical (IHC) examination revealed a phenotype consistent with MF with large cell transformation in the context of Sezary syndrome. The histological diagnosis of oral MF requires a high index of suspicion and IHC panel to rule out large cell transformation...
July 24, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28741124/characterization-of-a-low-density-lipoprotein-receptor-lrp13-in-chinese-tongue-sole-cynoglossus-semilaevis-and-medaka-oryzias-latipes
#16
Na Wang, Ruoqing Wang, Qiaomu Hu, Wenteng Xu, Ying Zhu, Fang Yan, Songlin Chen
As an important economic marine species cultured in China, Chinese tongue sole (Cynoglossus semilaevis) has interested us due to its sexual dimorphism and ZW/ZZ sex determination system. In a previous study, dmrt1 was identified as a dosage-dependent male-determining gene. In the present study, a female-specific expressed gene, cse0440, initially annotated as lrp1b-like, was identified from chromosome W of C. semilaevis. In view of the differences between cse0440 and lrp1b in terms of expression pattern, a phylogenetic analysis containing 85 LRP proteins was constructed and provided an evidence to re-annotate cse0440 as cseLRP13...
July 24, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28739712/total-glossectomy-without-laryngectomy-for-advanced-squamous-cell-cancer-of-the-tongue-functional-and-oncological-results
#17
Maximilian Reiter, Ulrich Harréus
BACKGROUND/AIM: Total glossectomy without laryngectomy for large tongue carcinomas still remains controversial, as these defects may go along with dramatic effects on respiration, speech and swallowing. As a consequence, these procedures significantly impact quality of life. Therefore, larger case series are rare. Nevertheless, with the development of free tissue transfer, functional reconstruction has become increasingly popular and encouraging results are reported in the literature...
August 2017: Anticancer Research
https://www.readbyqxmd.com/read/28738388/updated-friedman-staging-system-for-obstructive-sleep-apnea
#18
Michael Friedman, Anna M Salapatas, Lauren B Bonzelaar
In the practice of sleep medicine, the first step is identification of those patients at high risk for sleep apnea. Nearly every physician and every hospital has preferred methods of screening. Many patient questionnaires or surveys as well as some objective physical measurements have been suggested to predict the presence of sleep apnea. Screening is well established, and laboratory and home testing are widely available. An early assessment with a physical examination can help direct treatment planning. The Friedman tongue position, lingual tonsil hypertrophy grading, and the effects of oral positioning on the hypopharynx should be used in early assessment for treatment planning, and as screening tools to assess the sight of obstruction...
2017: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28738371/robotic-obstructive-sleep-apnea-surgery
#19
Song Tar Toh, Pon Poh Hsu
Since the first report of the use of the da Vinci robotic system (Intuitive Surgical, Sunnyvale, CA, USA) in transoral robotic tongue base reduction for obstructive sleep apnea (OSA) was published in 2010, this surgical tool and technique has been used worldwide for the resection of tongue base tissue in the multilevel surgical treatment of OSA. The combined knowledge of the published literature on its use has enlightened sleep surgeons worldwide on this new yet evolving surgical tool. Here we will discuss the use of the da Vinci robotic system in the treatment of OSA, the pertinent surgical anatomy for a safe surgical procedure, the primary and secondary outcomes to expect in the multilevel and primary use of this technology in treating the tongue base, the predictors for success or failure, and the complications associated with this technique...
2017: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28738368/updated-minimally-invasive-surgery-for-sleep-related-breathing-disorders
#20
Bhik Kotecha
Sleep-related breathing disorders (SRBD) consist of a variety of clinical entities, ranging from primary snoring to severe obstructive sleep apnoea at the opposite extreme. Although it has no official definition, minimally invasive surgery infers surgery where the procedure is clinically less aggressive and may involve a much smaller incision or none at all. It also implies that such procedures may result in a quicker recovery and reduced morbidity, and that they are often conducted under local anaesthesia as day cases...
2017: Advances in Oto-rhino-laryngology
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