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https://www.readbyqxmd.com/read/27920856/tongue-base-schwannoma-differential-diagnosis-and-imaging-features-with-a-case-presentation
#1
Zain Badar, Zerwa Farooq, Daniel Zaccarini, Sajeev R Ezhapilli
Schwannomas are slow growing, encapsulated neoplasms that arise from the nerve sheath. A vast majority of these benign neoplasms occur in the head and neck region, most commonly involving the 8th cranial nerve. Schwannomas arising from the base of tongue are very rare and, thus, can easily escape the list of differential diagnosis for a posterior tongue mass. A systematic approach is recommended for diagnosis of a posterior tongue mass, with neoplastic, infectious, and congenital categories. We report a case of a 24-year-old female, who presented with pressure sensation in the throat...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27920681/a-rare-case-of-mycosis-fungoides-in-the-oral-cavity-and-small-intestine-complicated-by-perforation
#2
Drew Arthur Emge, Juri Bassuner, Daniel J Lewis, Madeleine Duvic
Extracutaneous involvement in mycosis fungoides (MF) carries a poor prognosis. Oral and gastrointestinal (GI) tract lesions are both rare locations of disease. We describe the clinical findings of one case with oral and GI MF complicated by perforation after systemic antineoplastic treatment, and review the relevant literature. The patient had a 1-year history of MF before development of tongue and palate tumors. He was treated with local electron beam radiation, but re-presented to the hospital after what was found to be small intestine perforation following systemic antineoplastic therapy...
September 2016: Case Reports in Dermatology
https://www.readbyqxmd.com/read/27920287/teaching-neuroimages-hemigeographic-tongue-following-an-acute-ischemic-stroke
#3
Gregory Youngnam Chang, Montserrat G Delgado, Sergio Calleja
No abstract text is available yet for this article.
December 6, 2016: Neurology
https://www.readbyqxmd.com/read/27920027/sodium-taste-during-sodium-appetite
#4
Ralph Norgren
Sodium appetite appears to be an excellent model to study the neural mechanisms of motivation. In this issue of Chemical Senses, experiments by St John (2016) challenge 2 hypotheses for how a systemic sodium deficit guides an animal to find and ingest more Na ions in the environment. Both hypotheses deal with modifications of the sensory neural code produced by Na(+) ions on the tongue. One envisions a change in the Na(+) signal amplitude. A reduction could make the strong Na(+) signals less aversive; an increase, weak signals more noticeable...
December 5, 2016: Chemical Senses
https://www.readbyqxmd.com/read/27919991/homotypic-interaction-of-stabilin-2-plays-a-critical-role-in-lymph-node-metastasis-of-tongue-cancer
#5
Myung Woul Han, Jong Cheol Lee, Seung-Yoon Park, Young Min Kim, Kyung-Ja Cho, Seong Who Kim, Myungjin Lee, Soon Yuhl Nam, In-San Kim, Sang Yoon Kim
BACKGROUND/AIM: Lymph node (LN) metastasis of solid types of tumors has important clinical significance and it is therefore critical to identify molecular biomarkers that would enable the selection of patients with LN metastases. PATIENTS AND METHODS: We evaluated the expression of stabilin-2 in primary oral tongue tumors and metastatic LNs using immunohistochemical staining. The correlation between risk factors and nodal metastasis was assessed and disease-free survival was analyzed...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27919662/squamous-cell-carcinoma-of-the-anterior-tongue-is-tumour-thickness-an-indicator-for-cervical-metastasis
#6
P Loganathan, A Sayan, D W K Hsu, S Paraneetharan, V Ilankovan
The incidence of squamous cell carcinoma (SCC) of the tongue accounts for 90% of all malignancies affecting the oral cavity and oropharynx. The distribution between the anterior and posterior tongue is equal. Nodal metastasis is dependent on various factors including tumour thickness, site, size, differentiation, and perineural and perivascular invasion. There is increasing evidence of a close correlation between tumour thickness and metastasis. A retrospective study covering the 16-year period from 2000 to 2016 was performed...
December 2, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27918739/extra-tongue-oral-granular-cell-tumor-histological-and-immunohistochemical-aspect
#7
P-L Tobouti, F-M Pigatti, M-C Martins-Mussi, B-T Sedassari, S-C Orsini-Machado de Sousa
BACKGROUND: Granular cell tumor (GCT) is an uncommon benign tumor founded in any part of the body but mainly in the tongue. Extra-tongue oral granular cell tumor (ETOGCT) is rare with few cases reported. Here we describe seven cases of oral GCT located in sites other then the tongue and discuss histopathological and immunohistochemical differences between differential diagnoses Material and Methods: We retrieved all cases diagnosed with oral granular cell tumor, from the Oral Pathology Service at the School of Dentistry/ University of São Paulo, and excluded the ones sited in the tongue...
December 6, 2016: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/27917797/investigation-of-macc1-gene-expression-in-head-and-neck-cancer-and-cancer-stem-cells
#8
Ebu Evran, Hilal Şahin, Kübra Akbaş, Sadik Çiğdem, Esra Gündüz
PURPOSE: By investigating the MACC1 gene (metastasis-associated in colon cancer 1) in cancer stem cells (CSC) resistant to chemotherapy and in cancer stem cells (CSC) resistant to chemotherapy and in cancer cells (CS) sensitive to chemotherapy we determineda steady expression in both types of cells in head and neck cancer. In conformity with the result we examined if this gene could be a competitor gene for chemotherapy. According to literature, the MACC1 gene shows a clear expression in head and neck cancer cells [1]...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27916172/neck-dissection-versus-watchful-waiting-in-early-squamous-cell-carcinoma-of-the-tongue-our-experience-on-127-cases
#9
Giovanni Dell'Aversana Orabona, Paola Bonavolontà, Fabio Maglitto, Marco Friscia, Giorgio Iaconetta, Luigi Califano
BACKGROUND: Early oral squamous cell carcinoma (EOSCC) represents about 90% of the oral cancers especially in older males. The etiology is multifactorial, strongly related to tobacco and alcohol abuse, but also infective agents, Human papillomaviruses (HPV16-18), genetic factors and pre-neoplastic lesions seem to be implicated. There is no consensus in the literature for the treatment of early squamous cell carcinoma of the tongue (stages I-II); both an elective neck dissection policy and a watchful-waiting policy have their proponents in the different centers...
December 2016: Surgical Oncology
https://www.readbyqxmd.com/read/27915244/antifungal-activity-in-vitro-and-in-vivo-of-a-salmon-protamine-peptide-and-its-derived-cyclic-peptide-against-candida-albicans
#10
Jun-Ichi Nagao, Tamaki Cho, Makoto Mitarai, Keishi Iohara, Kazumi Hayama, Shigeru Abe, Yoshihiko Tanaka
Protamine peptides (PP) derived from salmon are 14-mer consisting of 10 arginine residues. We investigated the in vitro and in vivo antifungal activity of PP against Candida albicans PP showed the concentration-dependent dual mode of action; fungicidal activity and inhibitory activity of hyphal development in vitro. At lethal concentration of PP, intracellular accumulation of PP was energy-dependent but independent of endocytosis that resulted in ATP efflux and the generation of reactive oxygen species in the cells...
December 2, 2016: FEMS Yeast Research
https://www.readbyqxmd.com/read/27914206/is-ultrasound-a-valid-and-reliable-imaging-modality-for-airway-evaluation-an-observational-computed-tomographic-validation-study-using-submandibular-scanning-of-the-mouth-and-oropharynx
#11
Faraj W Abdallah, Eugene Yu, Phantila Cholvisudhi, Ahtsham U Niazi, Ki J Chin, Sherif Abbas, Vincent W Chan
OBJECTIVES: Ultrasound (US) imaging of the airway may be useful in predicting difficulty of airway management (DAM); but its use is limited by lack of proof of its validity and reliability. We sought to validate US imaging of the airway by comparison to CT-scan, and to assess its inter- and intra-observer reliability. We used submandibular sonographic imaging of the mouth and oropharynx to examine how well the ratio of tongue thickness to oral cavity height correlates with the ratio of tongue volume to oral cavity volume, an established tomographic measure of DAM...
December 3, 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27914100/transient-immunological-and-clinical-effectiveness-of-treating-mice-bearing-premalignant-oral-lesions-with-pd-1-antibodies
#12
Corinne A Levingston, M Rita I Young
A carcinogen-induced premalignant oral lesion model that progresses to oral cancer was used to examine the impact of blocking PD-1 on cytokine expression and on progression of lesions to cancer. The results of this study show increased production of IL-2 and the inflammatory cytokines IL-6, IL-17 and TNF-α by spleen cells of lesion-bearing mice that were treated with PD-1 antibody for one week compared to cytokine production by spleen cells of lesion-bearing mice treated with control antibody. Production of IFN-γ increased at 3 weeks of PD-1 antibody treatment, although production of the other Th1 and inflammatory mediators declined...
December 3, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27913971/myofunctional-therapy-improves-adherence-to-continuous-positive-airway-pressure-treatment
#13
Giovana Diaféria, Rogerio Santos-Silva, Eveli Truksinas, Fernanda L M Haddad, Renata Santos, Silvana Bommarito, Luiz C Gregório, Sergio Tufik, Lia Bittencourt
PURPOSE: Few studies have investigated myofunctional therapy in patients with obstructive sleep apnea syndrome (OSAS). The objective of this study was to evaluate the effect of myofunctional therapy on continuous positive airway pressure (CPAP) adherence. METHODS: The study was registered at ClinicalTrials.gov (NCT01289405). Male patients with OSAS were randomly divided into four treatment groups: placebo, patients undergoing placebo myofunctional therapy (N = 24); myofunctional therapy, undergoing myofunctional therapy (N = 27); CPAP, undergoing treatment with CPAP (N = 27); and combined, undergoing CPAP therapy and myofunctional therapy (N = 22)...
December 2, 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27913866/communicating-branches-between-lingual-and-hypoglossal-nerve-observation-using-sihler-s-staining-technique
#14
Joe Iwanaga, Koichi Watanabe, Tsuyoshi Saga, Yoko Tabira, Moriyoshi Nakamura, Christian Fisahn, R Shane Tubbs, Jingo Kusukawa, Koh-Ichi Yamaki
PURPOSE: Many dental procedures are at risk of injuring the lingual nerve. We performed this study to better elucidate the microanatomy that exists between the ipsilateral lingual and hypoglossal nerves so that iatrogenic injury can be avoided. METHODS: Adult human cadaveric tongues (ten sides) underwent Sihler's staining to identify the microanatomy between the lingual and hypoglossal nerves. RESULTS: The lingual nerve entered the middle part of the anterior two-thirds of the tongue from its lateral side and divided into two to four thick branches...
December 2, 2016: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/27913306/effect-of-bradykinin-receptor-antagonism-on-ace-inhibitor-associated-angioedema
#15
Brittany T Straka, Claudia E Ramirez, James B Byrd, Elizabeth Stone, Alencia Woodard-Grice, Hui Nian, Chang Yu, Aleena Banerji, Nancy J Brown
BACKGROUND: The B2 receptor antagonist icatibant is approved for treatment of attacks of hereditary angioedema. Icatibant has been reported to decrease time-to-resolution of angiotensin-converting enzyme (ACE) inhibitor-associated angioedema in one study of European patients. METHODS: Patients with ACE inhibitor-associated angioedema (defined as swelling of lips, tongue, pharynx or face during ACE inhibitor use and no swelling in the absence of ACE inhibitor use) were enrolled at Vanderbilt University Medical Center from October 2007 through September 2015 and at Massachusetts General Hospital in 2012...
November 29, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27909594/knowledge-of-the-research-assistants-regarding-local-anaesthetics-and-toxicity
#16
Derya Karasu, Canan Yılmaz, Şeyda Efsun Özgünay, Mürüvvet Dayıoğlu, Çağdaş Baytar, Gülsen Korfalı
OBJECTIVE: Cardiovascular system depression, respiratory arrest, coma, convulsions, loss of consciousness, muscle twitching, blurred vision, vertigo, dizziness and numbness of the tongue can be seen in local anaesthetic toxicity. Treatment includes 20% lipid solutions, airway control, symptomatic treatment for arrhythmia and convulsions. The aim of this study is to present the knowledge of research assistants, who used local anaesthetics in daily practice, regarding these medications and toxicity treatment and to raise awareness...
August 2016: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/27908710/prognosis-of-oral-squamous-cell-carcinoma-patients-with-level-iv-v-metastasis-an-observational-study
#17
Takumi Hasegawa, Yasuyuki Shibuya, Daisuke Takeda, Eiji Iwata, Izumi Saito, Yasumasa Kakei, Akiko Sakakibara, Masaya Akashi, Tsutomu Minamikawa, Takahide Komori
PURPOSE: The objectives of this study were to retrospectively describe the characteristics and outcomes of patients with oral squamous cell carcinoma (OSCC) with level IV/V metastases, and to evaluate the multivariate relationships among potential risk factors for metastasis and prognosis. MATERIALS AND METHODS: We evaluated 291 patients (178 men and 113 women; mean age, 65.9 ± 13.5 years). Clinicopathological data, time of development of level IV/V metastases, and clinical course were investigated...
October 29, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27908069/associations-between-tongue-movement-pattern-consistency-and-formant-movement-pattern-consistency-in-response-to-speech-behavioral-modifications
#18
Antje S Mefferd
The degree of speech movement pattern consistency can provide information about speech motor control. Although tongue motor control is particularly important because of the tongue's primary contribution to the speech acoustic signal, capturing tongue movements during speech remains difficult and costly. This study sought to determine if formant movements could be used to estimate tongue movement pattern consistency indirectly. Two age groups (seven young adults and seven older adults) and six speech conditions (typical, slow, loud, clear, fast, bite block speech) were selected to elicit an age- and task-dependent performance range in tongue movement pattern consistency...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27906850/isolated-hypoglossal-nerve-palsy-mimicking-a-base-of-tongue-tumor
#19
Daniela Francesca Nestola, Mariangela Lombardi, Matteo Brucoli, Francesco Pia, Paolo Aluffi
Isolated paralysis of hypoglossal nerve is uncommon, generally being associated with other neuropathies. A careful differential diagnosis is necessary to recognize the underlying diseases, some of which can be life-threatening. The authors report a patient of an 80-year-old woman presenting with an isolated hypoglossal palsy, mimicking a tongue neoplasm. Through a careful clinical workup and thanks to the aid of the imaging, it was possible to identify the presence of signal alterations due to a subacute denervation of the affected hemitongue and to exclude the presence of a tumor...
November 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27906519/can-newborn-infants-imitate
#20
REVIEW
Susan Jones
For several decades, scientists have held that newborn human infants can imitate adult behaviors like mouth opening, tongue protruding, and finger movements. This has been difficult to explain. In particular, it is not clear how newborn infants could know enough about their own bodies and movements, and how these map onto the bodies and movements of others, to be able to match their own felt movements to the seen movements of others. Prominent theories posit the existence of inborn mechanisms that automatically link visual input from the movements of others to the infant's already existing motor programs to produce the same movements...
December 1, 2016: Wiley Interdisciplinary Reviews. Cognitive Science
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