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https://www.readbyqxmd.com/read/28636983/the-influence-of-marital-status-on-survival-in-patients-with-oral-tongue-squamous-cell-carcinoma
#1
Wei Sun, Zeting Qiu, Wulin Tan, Zhongqi Liu, Zhongxing Wang, Wenqi Huang, Minghui Cao
Marital status was found to be an independent prognostic factor for survival in several cancers. However related researches of oral tongue squamous cell carcinoma (OTSCC) are still rare. We explored the Surveillance, Epidemiology, and End Results (SEER) program and finally identified 14,194 patients with OTSCC. Kaplan-Meier analysis and multivariate Cox regression models were used to distinguish risk factors for overall survival (OS) and tumor cause-specific survival (TCSS). Widowed patients had the highest percentage of female, highest average ages and more prevalence with localized SEER Stage significantly, while patients in the single group were younger than other groups...
June 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28634864/diagnostic-indicators-for-blood-stasis-syndrome-patients-with-gynaecological-diseases
#2
Jeeyoun Jung, Mi Mi Ko, Myeong Soo Lee, So Min Lee, Ju Ah Lee
OBJECTIVE: To investigate the important diagnostic indicators for blood stasis syndrome (BSS) in patients of childbearing age with gynaecological diseases. METHODS: A partial least squared-discriminant analysis (PLS-DA) were applied to BSS symptoms data of patients with gynaecological diseases, and the diagnostic indicators used by doctors of Korean medicine (DKMs) among BSS patients with gynaecological diseases were also investigated. RESULTS: A total of 103 patients of childbearing age with gynaecological diseases and 40 healthy controls were enrolled...
June 20, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28634310/-a-case-of-coexistent-glossopharyngeal-neuralgia-and-hemifacial-spasm-successfully-treated-with-transposition-of-the-vertebral-artery
#3
Takashi Fujii, Naoki Otani, Yohei Otsuka, Takashi Matsumoto, Shunsuke Tanoue, Hideaki Ueno, Satoshi Tomura, Arata Tomiyama, Terushige Toyooka, Kojiro Wada, Kentaro Mori
A case of coexistent glossopharyngeal neuralgia and hemifacial spasm was treated by transposition of the vertebral artery. A 60-year-old man was referred to our hospital due to pain in the left posterior part of the tongue that was difficult to control with oral medication at a local hospital. The diagnosis was left glossopharyngeal neuralgia based on the symptoms, imaging findings, and lidocaine test results. Moreover, the patient had left hemifacial spasm. Microvascular decompression was performed, which confirmed that the vertebral artery was compressing the lower cranial nerve and the posterior inferior cerebellar artery was compressing the root exit zone of the facial nerve...
June 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28633657/patient-safety-culture-in-norwegian-nursing-homes
#4
Gunnar Tschudi Bondevik, Dag Hofoss, Bettina Sandgathe Husebø, Ellen Catharina Tveter Deilkås
BACKGROUND: Patient safety culture concerns leader and staff interaction, attitudes, routines, awareness and practices that impinge on the risk of patient-adverse events. Due to their complex multiple diseases, nursing home patients are at particularly high risk of adverse events. Studies have found an association between patient safety culture and the risk of adverse events. This study aimed to investigate safety attitudes among healthcare providers in Norwegian nursing homes, using the Safety Attitudes Questionnaire - Ambulatory Version (SAQ-AV)...
June 20, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28633143/tumor-associated-macrophages-in-the-development-of-4-nitroquinoline-1-oxide-induced-tongue-squamous-cell-carcinoma-in-a-mouse-model
#5
Kentaro Miki, Yorihisa Orita, Yuka Gion, Soshi Takao, Kyotaro Ohno, Mai Takeuchi, Toshihiro Ito, Akira Minoura, Tomoyasu Tachibana, Hidenori Marunaka, Takuma Makino, Akihiro Matsukawa, Kazunori Nishizaki, Tadashi Yoshino, Yasuharu Sato
OBJECTIVE: We aimed to determine the distribution of tumor-associated macrophages (TAMs) in the development of tongue squamous cell carcinoma (SCC) and to elucidate the role of TAMs in the progression of tongue SCC. METHODS: The expression of the macrophage markers nitric oxide synthase, Retnla, and mannose receptor 1 in the development of tongue SCC was longitudinally observed using real-time quantitative polymerase chain reaction. Additionally, an immunohistochemical study using an anti-mannose receptor (MR) antibody was performed...
June 21, 2017: Oncology
https://www.readbyqxmd.com/read/28632936/peritumoral-cuffing-by-t-cell-tumor-infiltrating-lymphocytes-distinguishes-hpv-related-oropharyngeal-squamous-cell-carcinoma-from-oral-cavity-squamous-cell-carcinoma
#6
Kate Poropatich, David Hernandez, Joel Fontanarosa, Koshonna Brown, Gayle Woloschak, Ajit Paintal, Kirtee Raparia, Sandeep Samant
BACKGROUND: It is unclear why human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) has improved clinical behavior compared to HPV-negative HNSCC. We sought to better characterize the immune microenvironment of tongue cancers by examining the CD3 and CD8 TIL pattern in HPV-positive and -negative tumors. METHODS: Histologic sections from 40 oral tongue and oropharyngeal cases were analyzed (n= 21 HPV DNA-positive, n= 19 HPV DNA-negative)...
June 20, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28632881/clinically-available-assessment-measures-for-lingual-and-labial-somatosensation-in-healthy-adults-normative-data-and-test-reliability
#7
Nicole M Etter, Olivia M Miller, Kirrie J Ballard
Purpose: High-quality orofacial somatosensory inputs are essential for achieving rapid and accurate motor outputs. Little somatosensory testing is currently being completed in clinical settings. The purpose of this study is to assess the feasibility and test-retest reliability of clinical assessment tools for orofacial somatosensory testing in healthy young adults. Method: A total of 45 healthy young adults (ages 20-41 years) was recruited. Participants reported basic health information, completed pure-tone hearing thresholds, and were assessed using two-point discrimination discs and Von Frey hair detection and discrimination thresholds for bilateral lip and tongue...
June 20, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28631912/-results-of-urethral-reconstruction-in-adults-after-multiple-hypospadias-repairs
#8
S I Gamidov, M G Shneiderman, D Yu Pushkar, A O Vasil'ev, A V Govorov, R I Ovchinnikov, A Yu Popova, R D Dusmukhamedov
AIM: To improve treatment results in patients after multiple hypospadias repairs by optimizing the postoperative management. MATERIALS AND METHODS: Eighty-two patients (mean age 48.1+/-15.3 years) with urethral strictures secondary to failed hypospadias repairs underwent staged graft urethroplasty using oral mucosa (cheek, lip, tongue) as a grafting material. In 62 patients, at the end of surgery the bladder was drained with a standard Foley catheter. In twenty patients the bladder was drained with a modified silicone urethral catheter, which had an additional channel for delivering drugs and removing the urethral wound effluent, and a second additional channel for inflating a balloon fixed to the catheter tube at different parts of the catheter...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28631549/comparison-of-histological-and-proliferation-features-of-canine-oral-squamous-cell-carcinoma-based-on-intraoral-location-36-cases
#9
Lisa A Mestrinho, Hugo Pissarra, Sandra Carvalho, Maria C Peleteiro, Jerzy Gawor, Maria M R E Niza
Grade and labeling indices for immunohistochemical tumor proliferation markers Ki-67 and proliferating cell nuclear antigen (PCNA) were evaluated in 36 cases of canine oral squamous cell carcinoma (OSCC) based upon intraoral location. Grade was significantly associated with location ( P = .035). Grade II tumors were most frequently diagnosed. Grade I tumors were identified in the gingiva and the buccal mucosa, and grade III tumors were seen in the gingiva and the tonsillar region. Animals with tumors arising from the tonsils and of the tongue tended to be older ( P = ...
June 2017: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28631315/a-two-year-study-of-%C3%AE-9-tetrahydrocannabinol-concentrations-in-drivers-part-2-physiological-signs-on-drug-recognition-expert-dre-and-non-dre-examinations
#10
Kari Declues, Shelli Perez, Ariana Figueroa
Whole blood samples were examined for ∆(9) -Tetrahydrocannabinol (THC) over 2 years in drivers suspected of driving under the influence. Part one of the study examined the link between [THC] and performance on field sobriety tests. This portion examined objective signs, eye examinations and physiological indicators; and their relationship to the presence of THC. Several objective signs were excellent indicators of the presence of THC: red eyes (94%), droopy eyelids (85.6%), affected speech (87.6%), tongue coating (96...
June 20, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28631205/chemical-tongues-and-noses-based-upon-conjugated-polymers
#11
REVIEW
Jan Freudenberg, Felix Hinkel, Daniel Jänsch, Uwe H F Bunz
We report the uses of conjugated polymers in multisensory applications and in chemical and optoelectronic tongues. We look at the potential of single polymers to discriminate multiple analytes and into small libraries of conjugated polymers that represent sensors. These small libraries combine several barely selective, promiscuous sensor elements and react with the analytes in a fairly non-selective fashion by change of color, emission wavelength, or emission intensity. In such optoelectronic noses and tongues, response of a single element is not specific or particularly useful at all, but the response pattern after the combination of several sensor elements is often specific for an analyte and allows discrimination and identification without any problem...
August 2017: Topics in Current Chemistry (Journal)
https://www.readbyqxmd.com/read/28631164/studies-on-vertical-transmission-of-trichinella-spiralis-in-experimentally-infected-guinea-pigs-cavia-porcellus
#12
Eliana Riva, Cesar Fiel, Gisele Bernat, Sebastián Muchiut, Pedro Steffan
An experimental study to enhance knowledge on the capability of Trichenella spiralis to pass from guinea pigs to progeny at different periods of pregnancy or lactation was performed. For this purpose, 18 female adult guinea pigs were inoculated with 100 or 1000 T. spiralis muscle larvae (ML) during early, late gestation and during lactation period. The presence of T. spiralis (ML) in mothers and newborns was studied through enzymatic digestion from muscle samples. ML were observed in 9 of 42 newborn guinea pigs and levels of infection were significantly higher when infections of mothers were done during late gestation (p = 0...
June 19, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28628432/black-hairy-tongue-cured-concurrently-with-respiratory-infection
#13
Fátima Tous-Romero, Sara Burillo-Martínez, Marta Prieto-Barrios, Lidia Maroñas-Jiménez
No abstract text is available yet for this article.
June 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28628354/soft-tissue-enhancement-and-implant-placement-following-partial-mandibulectomy-due-to-squamous-cell-carcinoma
#14
Fabio Bernardello, Giampietro Bertasi, Ralph Mackey Powers, Sergio Spinato, Andrea Viaggi, Jimmie Bullock, Pietro Felice
Many dental procedures allow for implant placement in partially or totally edentulous patients. Despite the availability of various implant and abutment types on the market, it often becomes quite challenging to achieve the biological and esthetic goals in a patient who has ridge deficiencies. Where problems will arise is from the lack of adequate bone quality and quantity.1,2 Soft tissue form and maintenance is also a consideration to evaluate.3 Primary reconstructive techniques following segmental mandibulectomy is evolving and improves quality of life...
June 19, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28628162/-distant-metastases-of-malignant-salivary-gland-carcinoma-after-treated-by-125-i
#15
(no author information available yet)
OBJECTIVE: To investigate clinical features of distant metastases from malignant salivary gland carcinomas after treated by (125)I internal brachy therapy alone. METHODS: Between 2002 and 2010, 43 patients with locally advanced unresectable or recurrent malignant salivary gland carcinomas were treated by (125)I internal brachy therapy alone at Peking University School and Hospital of Stomatology. All of them had been follow-up at least 2 years. The primary sites of malignant salivary gland carcinomas were the parotid for 12 patients, infratemporal fossa for 9 patients, tongue for 7 patients, maxilla for 6 patients, parapharyngeal for 4 patients, floor of months for 3 patients, submandibular gland for 1 patient, and lip for 1 patient...
June 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28626254/the-maximum-standardized-uptake-value-increment-calculated-by-dual-time-point-18-f-fluorodeoxyglucose-positron-emission-tomography-predicts-survival-in-patients-with-oral-tongue-squamous-cell-carcinoma
#16
Natsuki Yonezawa, Tsutomu Minamikawa, Kazuhiro Kitajima, Yusuke Takahashi, Ryohei Sasaki, Ken-Ichi Nibu, Takahide Komori
The aim of this study was to investigate the prognostic value of dual-time-point (DTP) (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) imaging in primary oral tongue squamous cell carcinoma (OTSCC). The study included 52 patients who underwent preoperative (18)F-FDG PET scans at two time points, namely 1 h and 2 h after injection. The following PET parameters were calculated: maximum standardized uptake value (SUVmax) for both time points (SUV early, SUV delayed); retention index (RI); and SUVmax increment (ΔSUVmax)...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28625010/treatment-of-tongue-base-masses-in-children-by-transoral-robotic-surgery
#17
Fatma Tulin Kayhan, Ayse Pelin Yigider, Arzu Karaman Koc, Kamil Hakan Kaya, Ibrahim Erdim
The feasibility and effectiveness of transoral robotic surgery (TORS) in children with tongue base masses (TBMs) were evaluated. Eight pediatric patients who were treated with TORS for TBMs between January 2010 and January 2016 at a tertiary hospital included in the study. All pathologies were congenital lesions: four were lingual thyroglossal ductus cysts (LTGDCs), one was a minor salivary gland tumor, one was a vallecular cyst, one was a bronchogenic cyst, and one was an ectopic thyroid tissue. TORS was performed successfully in all cases...
June 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28624163/simultaneous-congenital-mucocoele-of-the-blandin-n%C3%A3-hn-glands-and-teratoma-of-the-tongue-early-management-and-follow-up-at-one-year
#18
Nathalie Pham Dang, Anne-Claire Melka, Hélène Laurichesse Delmas, Isabelle Barthélémy
Mucocoele of the Blandin-Nühn glands and teratomas of the tongue are rare in newborn babies. We present what is to our knowledge the first documented case of both at the same time, and describe management and follow up over 12 months after the birth. Prenatal diagnosis defined the treatment plan during delivery to establish an airway for the baby promptly. A normal delivery is possible if the cyst is anterior, and can be punctured during delivery. Delayed excision reduces the possibility of oedema and obstruction of the airway, ensures complete resection, avoids recurrence, and confirms the diagnosis...
June 14, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28623555/goldenhar-syndrome-current-perspectives
#19
REVIEW
Katarzyna Bogusiak, Aleksandra Puch, Piotr Arkuszewski
BACKGROUND: Progress in medical branches that has taken place since the first child with Goldenhare syndrome (GS) had been described in 1952 by Maurice Goldenhar, facilitated better understanding of this congenital defect. It also gave new perspectives and the opportunity to achieve satisfactory treatment results, mainly due to development of surgical techniques. DATA SOURCES: Based on the literature and own experience, we discussed the phenotype of presentation of GS, ethiopathogenesis, genetic counselling and treatment with particular emphasis on surgery correction of hemifacial microsomia...
June 15, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28623290/tcrp1-transcriptionally-regulated-by-c-myc-confers-cancer-chemoresistance-in-tongue-and-lung-cancer
#20
Xiaoting Jia, Zhijie Zhang, Kai Luo, Guopei Zheng, Minying Lu, Ying Song, Hao Liu, Huisi Qiu, Zhimin He
Previously, we cloned a new gene termed 'tongue cancer resistance-associated protein 1' (TCRP1), which modulates tumorigenesis, enhances cisplatin (cDDP) resistance in cancers, and may be a potential target for reversing drug resistance. However, the mechanisms for regulating TCRP1 expression remain unclear. Herein, we combined bioinformatics analysis with luciferase reporter assay and ChIP assay to determine that c-Myc could directly bind to TCRP1 promoter to upregulate its expression. TCRP1 upregulation in multidrug resistant tongue cancer cells (Tca8113/PYM) and cisplatin-resistant A549 lung cancer cells (A549/DDP) was accompanied by c-Myc upregulation, compared to respective parental cells...
June 16, 2017: Scientific Reports
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