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https://www.readbyqxmd.com/read/28931192/markers-of-proliferation-and-cytokeratins-in-the-differential-diagnosis-of-jaw-cysts
#1
Nikola D Živković, Dragan S Mihailović, Miloš S Kostić, Ana S Cvetanović, Žaklina Ž Mijović, Maja V Milentijević, Tijana V Denčić
We conducted a retrospective study to analyze the histologic and immunohistochemical findings in three main types of odontogenic cyst. We studied 90 archived cystic jaw lesions: 30 dentigerous cysts, 30 keratocystic odontogenic tumors, and 30 radicular cysts. The cyst types were identified on the basis of clinical, radiologic, and histopathologic findings. Immunohistochemical analyses included staining with Ki-67, p53, epidermal growth factor receptor (EGFR), cytokeratin (CK) 8, CK14, CK17, and CK18. Cell immunopositivity was evaluated for the entire epithelium...
September 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28930927/oral-behaviors-and-parafunctions-comparison-of-temporomandibular-dysfunction-patients-and-controls
#2
Marijus Leketas, Viktoras Šaferis, Ričardas Kubilius, Gabriele Cervino, Ennio Bramanti, Marco Cicciù
The aim of this study is to evaluate the frequency of oral behaviors in patients with temporomandibular disorders (TMD) and a control group without TMD.In this baseline case-control study, 260 controls and 260 subjects with TMD completed the oral behaviors checklist defined as a "self-report scale for identifying and quantifying the frequency of jaw overuse behavior" and underwent clinical examinations using the DC/TMJ international examination form (version May 12, 2013). Relationships of oral parafunctions' frequencies between groups were examined...
September 19, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28929308/influence-of-obesity-on-experimental-periodontitis-in-rats-histopathological-histometric-and-immunohistochemical-study
#3
Elizangela Partata Zuza, Valdir Gouveia Garcia, Letícia Helena Theodoro, Edilson Ervolino, Luiz Fernando Veloso Favero, Mariéllen Longo, Fernando Salimon Ribeiro, Alex Tadeu Martins, Luís Carlos Spolidorio, José Antônio Sampaio Zuanon, Benedicto Egbert Corrêa de Toledo, Juliana Rico Pires
OBJECTIVES: This study assessed the influence of obesity on the progression of ligature-induced periodontitis in rats. MATERIALS AND METHODS: Forty-eight adult Wistar rats were randomly divided into two groups: the HL group (n = 24) was fed high-fat animal food to induce obesity, and the NL group (n = 24) was fed normolipidic animal food. Obesity was induced within a period of 120 days, and the induction of experimental periodontitis (EP) was subsequently performed for 30 days...
September 19, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28929117/histological-evidence-of-the-osseointegration-of-fractured-direct-metal-laser-sintering-implants-retrieved-after-5-years-of-function
#4
Francesco Mangano, Carlo Mangano, Adriano Piattelli, Giovanna Iezzi
BACKGROUND: Direct metal laser sintering (DMLS) is an additive manufacturing technique that allows the fabrication of dental implants layer by layer through the laser fusion of titanium microparticles. The surface of DMLS implants is characterized by a high open porosity with interconnected pores of different sizes; therefore, it has the potential to enhance and accelerate bone healing. To date, however, there are no histologic/histomorphometric studies in the literature evaluating the interface between bone and DMLS implants in the long-term...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28928654/adenosine-receptor-stimulation-improves-glucocorticoid-induced-osteoporosis-in-a-rat-model
#5
Gabriele Pizzino, Natasha Irrera, Federica Galfo, Giacomo Oteri, Marco Atteritano, Giovanni Pallio, Federica Mannino, Angelica D'Amore, Enrica Pellegrino, Federica Aliquò, Giuseppe P Anastasi, Giuseppina Cutroneo, Francesco Squadrito, Domenica Altavilla, Alessandra Bitto
Glucocorticoid-induced osteoporosis (GIO) is a secondary cause of bone loss. Bisphosphonates approved for GIO, might induce jaw osteonecrosis; thus additional therapeutics are required. Adenosine receptor agonists are positive regulators of bone remodeling, thus the efficacy of adenosine receptor stimulation for treating GIO was tested. In a preventive study GIO was induced in Sprague-Dawley rats by methylprednisolone (MP) for 60 days. Animals were randomly assigned to receive polydeoxyribonucleotide (PDRN), an adenosine A2 receptor agonist, or PDRN and DMPX (3,7-dimethyl-1-propargylxanthine, an A2 antagonist), or vehicle (0...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28927924/digital-immediate-denture-a-clinical-report
#6
Jing-Huan Fang, Xueyin An, Seung-Mi Jeong, Byung-Ho Choi
Fabricating an immediate complete denture in the conventional manner may be complicated and difficult. The purpose of this article was to describe a fully digital workflow used to fabricate an immediate complete denture before removing the teeth and without the use of conventional impressions or stone casts. The digital data for the workflow were acquired using an intraoral scanner and were then used to design the denture base and teeth after deleting any remaining tooth images from the virtual 3-dimensional image of the jaw...
September 16, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28922248/maxillary-corticotomies-with-bone-to-bone-retraction-and-mandibular-segmental-osteotomy-for-correcting-an-anterior-double-protrusion
#7
Kyung A Kim, Baek-Soo Lee, Ayse Selenge Akbulut, Seong-Hun Kim, Gerald Nelson
BACKGROUNDS: This article presents maxillary corticotomies with bone-to-bone retraction and anterior segmental osteotomy (ASO) as an alternative to 2-jaw orthognathics in the bimaxilary protrusion patient with partially anchylosed maxillary anterior tooth. METHODS: The 18-year-old male, complaining of anterior protrusion, with a trauma history to the maxillary central incisor, and requesting rapid treatment, was treated with maxillary corticotomies in 2 stages and ASO in the mandible...
September 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28921912/fate-of-worn-out-functional-teeth-in-the-upper-jaw-dentition-of-sicyopterus-japonicus-gobioidei-sicydiinae-during-tooth-replacement
#8
Noriyuki Sahara, Keita Moriyama, Midori Iida, Shun Watanabe
Mochizuki and Fukui (1983) studied the development and replacement of the upper jaw teeth in a Japanese fish species, Sicyopterus japonicus (Gobioidei: Sicydiinae), and they reported that worn-out functional teeth in the upper jaw were not shed outside the skin but were taken into the soft tissue of the upper jaw and completely resorbed there. To date, however, this phenomenon appears poorly documented. Furthermore, the mechanism for the resorption of these teeth remains to be determined. In the present study, we examined this phenomenon by using 3D micro-computed tomography (m-CT), scanning electron microscopy (SEM), and various techniques of light (LM) and electron (EM) microcopy...
September 16, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28920136/jaw-pain-in-a-pemphigus-patient-on-prednisolone-mycophenolate-mofetil-and-denosumab
#9
Pei Ming Yeo, Chia Chun Ang
No abstract text is available yet for this article.
August 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28920035/anesthesia-management-of-a-patient-with-papillon-lefevre-syndrome-a-case-report
#10
Afshin Iranpour, Ata Mahmoodpoor
INTRODUCTION: Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive trait; it often requires some interventions with general anesthesia because of the accompanied complications. CASE PRESENTATION: We report a 19-year-old girl with palmoplantar hyperkeratosis who presented total loss of her teeth. She was candidate to mandibular bone graft and lower jaw dental implants under general anesthesia. CONCLUSIONS: There are only a few studies about perioperative management of these patients; however, the anesthesiologists should consider a few important issues during pre-operative and intra-operative management...
February 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/28919696/potential-of-pomegranate-fruit-extract-punica-granatum-linn-to-increase-vascular-endothelial-growth-factor-and-platelet-derived-growth-factor-expressions-on-the-post-tooth-extraction-wound-of-cavia-cobaya
#11
Intan Nirwana, Priyawan Rachmadi, Devi Rianti
BACKGROUND: Pomegranates fruit extracts have several activities, among others, anti-inflammatory, antibacterial, and antioxidants that have the main content punicalagin and ellagic acid. Pomegranate has the ability of various therapies through different mechanisms. Vascular endothelial growth factor (VEGF) function was to form new blood vessels produced by various cells one of them was macrophages. Platelet-derived growth factor (PDGF) was a growth factor proven chemotactic, increased fibroblast proliferation and collagen matrix production...
August 2017: Veterinary World
https://www.readbyqxmd.com/read/28918879/axitinib-related-osteonecrosis-of-the-jaw
#12
Vinod Patel, Chris Sproat, Jerry Kwok, Nikki Tanna
Tyrosine kinase inhibitors (TKIs) are oral chemotherapy drugs used primarily to treat leukemias, renal cell carcinomas, gastrointestinal stromal tumors, and neuroendocrine tumors. Within this group, a number of drugs have already been implicated in jaw necrosis. Axitinib (Inlyta) is a novel TKI currently licensed for the treatment of renal cell carcinoma. We report the first case, to our knowledge, of jaw necrosis solely related to this medication and review the literature surrounding TKIs and their implication in osteonecrosis of the jaw...
August 18, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28916952/air-electron-stream-interactions-during-magnetic-resonance-igrt-skin-irradiation-outside-the-treatment-field-during-accelerated-partial-breast-irradiation
#13
Jong Min Park, Kyung Hwan Shin, Jung-In Kim, So-Yeon Park, Seung Hyuck Jeon, Noorie Choi, Jin Ho Kim, Hong-Gyun Wu
PURPOSE: To investigate and to prevent irradiation outside the treatment field caused by an electron stream in the air generated by the magnetic field during magnetic resonance image-guided accelerated partial breast irradiation (APBI). MATERIALS AND METHODS: In all, 20 patients who received APBI with a magnetic resonance image-guided radiation therapy (MR-IGRT) system were prospectively studied. The prescription dose was 38.5 Gy in 10 fractions of 3.85 Gy and delivered with a tri-cobalt system (the ViewRay system)...
September 15, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28916324/in%C3%A2-vitro-investigation-of-the-antimicrobial-effect-of-three-bisphosphonates-against-different-bacterial-strains
#14
Michael A Ermer, Simon C Kottmann, Jörg-Elard Otten, Annette Wittmer, Philipp Poxleitner, Klaus Pelz
PURPOSE: Since the first descriptions of medication-related osteonecrosis of the jaw (MRONJ) in 2003, the pathogenesis has remained unanswered. Recent histomorphometric studies have found several microorganisms, including Actinomyces, Bacillus, Fusobacterium, Staphylococcus, Streptococcus, Selenomonas, Treponema, and Candida albicans in necrotic bone. Polymerase chain reaction studies have recently confirmed the occurrence of 48 genera. Only a few studies have examined the antimicrobial effect of bisphosphonates (BPs)...
August 31, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28915955/implications-of-bisphosphonate-calcium-ion-depletion-interfering-with-desmosome-epithelial-seal-in-osseointegrated-implants-and-pressure-ulcers
#15
Louis Z G Touyz, Kelvin I Afrashtehfar
Osteoporosis (OP) is a global bone disease prevalent in aging in humans, especially in older women. Bisphosphonates (BPs) are commonly used as therapy for OP as it influences hard and soft tissues calcium metabolism. Mucosal and dermal ulceration with exposure of underlying bone arises from incomplete epithelial recovery due to reduced desmosome formation deriving from lack of available calcium. Pathological situations such as bisphosphonate-related osteonecrosis of the jaw have been described. This hypothesis states other situations which demand intact functional desmosomes such as healing skin over chronic pressure points leading to pressure ulcers (as well-known as bedsores, pressure sores, pressure injuries, decubitus ulcers), and hemidesmosomes such as epithelial seals in contact with titanium surfaces will have a higher prevalence of breakdown among patients being treated with BPs...
September 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28911792/facial-profile-and-frontal-changes-after-bimaxillary-surgery-in-patients-with-mandibular-prognathism
#16
Chun-Ming Chen, Michael Yuan-Chien Chen, Jung-Hsuan Cheng, Kwei-Jing Chen, Yu-Chuan Tseng
BACKGROUND/PURPOSE: Patients are always concerned about their postoperative appearance before surgery for facial deformity correction. The present study investigated the facial profile and frontal changes following two-jaw surgery. METHODS: Forty patients who underwent two-jaw surgery were divided by the amount of mandibular setback (group I: ≤8 mm and group II: >8 mm). Cephalometric radiograms (lateral and frontal) were collected and analyzed at three intervals: preoperatively (T1), immediately postoperatively (T2), and final follow-up (T3)...
September 11, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28906331/mandibular-surgical-navigation-an-innovative-guiding-method
#17
Vincenzo Abbate, Giovanni Dell' Aversana Orabona, Domenico Solari, Paola Bonavolontà, Giorgio Iaconetta, Luigi Califano
Mandibular osteotomies are usually required to treat craniomaxillofacial disorders. Losses of mandibular continuity result in esthetic and functional deficiency. During the past 30 years, the spread of the computer-assisted surgery techniques, rapid prototyping, and surgical navigation technique has improved the reliability and the outcomes of mandibular resections and reconstructions, by providing realtime feedback to surgeon. Recent studies reported the feasibility and the precision of surgical navigation applied to mandibular surgical resection and reconstruction with fibula flap but none of them describes a method to navigate the jaw allowing its full motility during the operation...
September 12, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28904311/retrospective-cohort-clinical-investigation-of-a-dental-implant-with-a-narrow-diameter-and-short-length-for-the-partial-rehabilitation-of-extremely-atrophic-jaws
#18
Paulo S Maló, Miguel A de Araújo Nobre, Armando V Lopes, Ana S Ferro
We investigated the short-term clinical outcomes of narrow-diameter short-length implants for the fixed-prosthetic partial rehabilitation of extremely resorbed jaws. Twenty-three patients requiring partial rehabilitations with narrow-platform short-length implants in any jaw were included in this study. In total, 30 implants 3.3 mm in diameter and 7 (n = 15 implants) or 8.5 (n = 15 implants) mm in length were inserted. The primary outcome measure was implant cumulative survival rate (CSR); the secondary outcome measures were marginal bone resorption at 1 and 3 years and the incidence of biologic and mechanical complications...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28903740/erratum-to-large-intragenic-deletion-of-cdc73-exons-4-10-in-a-three-generation-hyperparathyroidism-jaw-tumor-hpt-jt-syndrome-family
#19
Vito Guarnieri, Raewyn M Seaberg, Catherine Kelly, M Jean Davidson, Simon Raphael, Andrew Y Shuen, Filomena Baorda, Orazio Palumbo, Alfredo Scillitani, Geoffrey N Hendy, David E C Cole
No abstract text is available yet for this article.
September 13, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28902456/safety-and-efficacy-of-hydroxyapatite-scaffold-in-the-prevention-of-jaw-osteonecrosis-in-vivo
#20
Adriana Duarte de Almeida, Fernanda Gomes Leite, Marco Vinícius Chaud, Márcia de Araújo Rebelo, Liliane Cristine Ferreira de Souza Borges, Fabia Judice Marques Viroel, Alessandre Hataka, Denise Grotto
Two scaffolds of chitosan/sodium alginate/hydroxyapatite (Ch/NaAlg/Hap) 1:1:0.2 and 1:1:0.6 were evaluated in the prevention of bisphosphonate-induced jaw osteonecrosis. Two groups of rats (n = 24, according to the euthanasia time: 15 or 30 days after the last Zoledronic acid (ZA) administration) were subdivided in four subgroups (n = 6): I - Control (saline + teeth extraction); II - ZA 0.6 mg/kg + teeth extraction; III - ZA + teeth extraction + scaffold 1:1:0.2; IV - ZA + teeth extraction + scaffold 1:1:0...
September 13, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
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