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Surgical prophylaxis

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https://www.readbyqxmd.com/read/29773260/mechanical-bowel-preparation-and-oral-antibiotic-prophylaxis-in-colorectal-surgery-analysis-of-evidence-and-narrative-review
#1
Josep M Badia, Nares Arroyo-García
The role of oral antibiotic prophylaxis and mechanical bowel preparation in colorectal surgery remains controversial. The lack of efficacy of mechanical preparation to improve infection rates, its adverse effects, and multimodal rehabilitation programs have led to a decline in its use. This review aims to evaluate current evidence on antegrade colonic cleansing combined with oral antibiotics for the prevention of surgical site infections. In experimental studies, oral antibiotics decrease the bacterial inoculum, both in the bowel lumen and surgical field...
May 14, 2018: Cirugía Española
https://www.readbyqxmd.com/read/29772370/does-nasal-carriage-of-staphylococcus-aureus-increase-the-risk-of-post-operative-infections-after-elective-spine-surgery-do-most-infections-occur-in-carriers
#2
Owoicho Adogwa, Victoria D Vuong, Aladine A Elsamadicy, Daniel T Lilly, Shyam A Desai, Syed Khalid, Joseph Cheng, Carlos A Bagley
BACKGROUND: Wound infections following adult spinal deformity surgery place a high toll on patients, providers, and the healthcare system. Staphylococcus aureus is a common cause of postoperative wound infections, and nasal colonization by this organism may be an important factor development of surgical site infections (SSI's). The aim is to investigate whether post-operative surgical site infections after elective spine surgery occur at a higher rate in patients with Methicillin-Resistant Staphylococcus Aureus (MRSA) nasal colonization...
May 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29771900/inappropriate-prescribing-of-antibiotics-following-discharge-after-major-surgery-an-area-for-improvement
#3
Mary De Almeida, Catherine Gerrard, Joshua T Freeman, Eamon Duffy, Sally A Roberts
AIM: This study aims to determine the indications for antibiotic use in patients discharged following major surgery at Auckland City Hospital (ACH); to determine if the indications were appropriate and to identify opportunities where antimicrobial stewardship interventions would be beneficial. METHODS: This was a retrospective study of adult patients who were dispensed an antibiotic within the first two days of discharge after major surgery at ACH between 1 January 2013 and 31 December 2013...
May 18, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29766305/evaluation-of-vte-prophylaxis-and-the-impact-of-alternate-regimens-on-post-operative-bleeding-and-thrombotic-complications-following-bariatric-procedures
#4
Maria S Altieri, Jie Yang, Janos Hajagos, Konstantinos Spaniolas, Jihye Park, Antonios P Gasparis, Andrew T Bates, Salvatore Docimo, Mark Talamini, A Laurie Shroyer, Aurora D Pryor
BACKGROUND: Studies examining utilization and impact of venous thromboembolism (VTE) chemoprophylaxis for patients undergoing bariatric surgery are limited. Determination of the optimal prophylactic regimen to minimize complications is crucial. METHODS: The Cerner Health Facts database from 2003 to 2013 was queried using ICD-9 codes to identify patients undergoing laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (RYGB). VTE chemoprophylaxis regimens were divided into pre-operative alone (PreP), post-operative alone (PostP), both pre-operative and post-operative (PPP), or no prophylaxis (NP)...
May 15, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29765828/a-cross-sectional-survey-of-the-north-american-skull-base-society-on-vestibular-schwannoma-part-2-perioperative-practice-patterns-of-vestibular-schwannoma-in-north-america
#5
Jamie J Van Gompel, Matthew L Carlson, R Mark Wiet, Nicole M Tombers, Anand K Devaiah M, Devyani Lal, Jacques J Morcos, Michael J Link
Introduction  Perioperative care of vestibular schwannoma (VS) patients is extremely variable across surgeons and institutions making practice patterns difficult to standardize. No data currently exist detailing this practice variability. Methods  The North American Skull Base Society membership was electronically surveyed regarding perioperative care of surgically operated VS patients. Results  There were 87 respondents to the survey. Surgical positioning, surgical approach utilized, and perioperative medical adjuncts are quite variable...
June 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29765440/prevalence-of-bacteria-and-fungi-in-samples-of-cornea-preservation-fluid
#6
Grażyna Broniek, Ewa Langwińska-Wośko, Małgorzata Sybilska, Jerzy Szaflik, Jacek P Szaflik, Marta Wróblewska
Introduction: Recipients of corneal transplants are at risk of healthcare-associated infections, which, apart from other causes of surgical site infections, may also occur as a result of the transfer of infected corneal tissue. In this study we assessed the risk of bacterial and fungal infections based on the results of routine microbiological testing of cornea preservation fluid samples. Material and methods: We examined a total of 725 samples of corneal preservation fluid, obtained during a period of 3 years (2011-2013)...
April 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29764228/anti-infective-chemoprophylaxis-after-solid-organ-transplantation
#7
Paul J Deziel, Raymund Razonable
Solid organ transplant recipients are at high risk of opportunistic infections due to bacterial, viral, fungal and parasitic pathogens. Anti-infective prophylaxis is a time-tested proven strategy for the prevention of these infections after solid organ transplantation. Areas covered: The current recommendations for the prevention of surgical site infections, herpes simplex, cytomegalovirus, invasive fungal infections, and selected parasitic diseases are highlighted. Recent peer-reviewed publications on the prevention of infection after solid organ transplantation were reviewed and their significance was discussed in the context of the current recommendations for preventing infectious complications...
May 15, 2018: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/29760826/best-prophylactic-strategy-in-groups-at-risk-of-intraoperative-floppy-iris-syndrome-development-comparison-between-atropine-instillation-and-adrenaline-intracameral-injection
#8
Raffaele Nuzzi, Paolo Arnoffi, Federico Tridico
Background: Intraoperative Floppy Iris Syndrome (IFIS) is an important cause of surgical complications and iris defects in patients undergoing phacoemulsification that were treated with selective subtype α1A receptor antagonists for a long period of time. To date, no definitive preventive strategy has emerged, yet. The need of prophylaxis is dictated by the high prevalence of males affected by benign prostatic hyperplasia undergoing cataract surgery. Objective: To identify the best prophylactic strategy in groups at risk of IFIS development by comparing two mydriatic treatments in course of phacoemulsification surgery...
2018: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/29757897/coagulation-defects-in-the-cirrhotic-patient-undergoing-liver-transplantation
#9
Arabesque Parker, Constantine J Karvellas
Patients with cirrhosis undergoing liver transplantation have unique challenges with regard to the prevention and management of thrombosis and hemorrhage. Patients with cirrhosis have an unstable balance of the coagulation system due to defects in both prothrombotic and antithrombotic components. These changes make laboratory monitoring challenging, prophylaxis against bleeding and thrombosis controversial, and therapy for the same uncertain. When cirrhotic patients undergo liver transplantation they frequently have significant transfusion requirements...
May 7, 2018: Transplantation
https://www.readbyqxmd.com/read/29757781/misconceptions-surrounding-penicillin-allergy-implications-for-anesthesiologists
#10
Leon Vorobeichik, Elizabeth A Weber, Jordan Tarshis
Administration of preoperative antimicrobial prophylaxis, often with a cephalosporin, is the mainstay of surgical site infection prevention guidelines. Unfortunately, due to prevalent misconceptions, patients labeled as having a penicillin allergy often receive alternate and less-effective antibiotics, placing them at risk of a variety of adverse effects including increased morbidity and higher risk of surgical site infection. The perioperative physician should ascertain the nature of previous reactions to aid in determining the probability of the prevalence of a true allergy...
May 10, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29756330/postoperative-prophylactic-antibiotics-for-facial-fractures-a-systematic-review-and-meta-analysis
#11
REVIEW
Andy M Habib, Alexander D Wong, Geoffrey C Schreiner, Komal F Satti, Natalie B Riblet, Heather A Johnson, Jacob P Ossoff
OBJECTIVE: Perioperative antibiotic prophylaxis in patients undergoing surgery for maxillofacial fractures is standard practice. However, the use of postoperative antibiotic prophylaxis remains controversial. This systematic review and meta-analysis sought to evaluate the effect of postoperative antibiotic therapy on the incidence of surgical site infection (SSI) in patients with maxillofacial fractures. METHODS: MEDLINE, Embase, and the Cochrane Library were searched from inception through October 2017...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29745099/incidence-and-risk-assessment-of-venous-thromboembolism-in-cancer-patients-admitted-to-intensive-care-unit-for-postoperative-care
#12
Jia-Xuan Xu, Jun Dong, Hong Ren, Xiao-Jie Chen, Yong Yang, Ren-Xiong Chen, Guo-Dong Wang, Hong-Zhi Wang
PURPOSE: Cancer patients undergoing surgery are at high risk of venous thromboembolism (VTE). The occurrence of VTE in Chinese cancer patients admitted to intensive care unit (ICU) for postoperative care is poorly characterized. This study was designed to investigate the incidence of VTE in this population and to evaluate the utility of the Caprini score in risk stratification. METHODS: 2127 consecutive adult patients admitted to a 10-bed surgical ICU (SICU) in a tertiary care academic hospital during a 4-year period (January 1, 2013 - December 31, 2016) were enrolled...
January 2018: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29741289/grommets-ventilation-tubes-for-recurrent-acute-otitis-media-in-children
#13
REVIEW
Roderick P Venekamp, Paul Mick, Anne Gm Schilder, Desmond A Nunez
BACKGROUND: Acute otitis media (AOM) is one of the most common childhood illnesses. While many children experience sporadic AOM episodes, an important group suffer from recurrent AOM (rAOM), defined as three or more episodes in six months, or four or more in one year. In this subset of children AOM poses a true burden through frequent episodes of ear pain, general illness, sleepless nights and time lost from nursery or school. Grommets, also called ventilation or tympanostomy tubes, can be offered for rAOM...
May 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29735820/-fusarium-the-versatile-pathogen
#14
REVIEW
Ananya Tupaki-Sreepurna, Anupma Jyoti Kindo
Fusarium is an emerging human opportunistic pathogen of growing importance, especially among immunosuppressed haematology patients due to an increased incidence of disseminated infections over the past two decades. This trend is expected only to continue due to the advances in medical and surgical technologies that will prolong the lives of the severely ill, making these patients susceptible to rare opportunistic infections. Production of mycotoxins, enzymes such as proteases, angio-invasive property and an intrinsically resistant nature, makes this genus very difficult to treat...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29727872/postoperative-complications-in-equine-elective-clean-orthopaedic-surgery-with-without-antibiotic-prophylaxis
#15
Sabita Diana Stöckle, Klaus Failing, Marc Koene, Kerstin Fey
OBJECTIVE: Retrospective analysis of postoperative complications in equines after clean, orthopaedic surgical procedures in order to detect differences between animals treated with antibiotics and horses without receiving these drugs. MATERIAL AND METHODS: Details on 652 patients, surgical procedures and surgery-associated complications were compiled from horses being operated between June 2011 and January 2015. Antibiotic-receiving patients (n = 259) were tested for differences in complication rates and characteristics to controls (n = 393)...
April 2018: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/29726801/reduction-in-surgical-site-infection-with-suprafascial-intrawound-application-of-vancomycin-powder-in-instrumented-posterior-spinal-fusion-a-retrospective-case-control-study
#16
Shoichi Haimoto, Ralph T Schär, Yusuke Nishimura, Masahito Hara, Toshihiko Wakabayashi, Howard J Ginsberg
OBJECTIVE Recent studies have demonstrated the efficacy of subfascial intrawound application of vancomycin powder in spine surgery in reducing the rate of surgical site infections (SSIs). However, to date no study has evaluated the efficacy and safety of suprafascial application of vancomycin powder in spine surgery. The purpose of this study was to quantify the rate of SSIs after open instrumented posterior spinal fusion with and without application of suprafascial vancomycin powder and to evaluate the rate of vancomycin powder-related local adverse effects...
May 4, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29724214/multiple-challenges-of-antibiotic-use-in-a-large-hospital-in-ethiopia-a-ward-specific-study-showing-high-rates-of-hospital-acquired-infections-and-ineffective-prophylaxis
#17
Girma Gutema, Helle Håkonsen, Ephrem Engidawork, Else-Lydia Toverud
BACKGROUND: This project aims to study the use of antibiotics in three clinical wards in the largest tertiary teaching hospital in Ethiopia for a period of 1 year. The specific aims were to assess the prevalence of patients on antibiotics, quantify the antibiotic consumption and identify the main indications of use. METHOD: The material was all the medical charts (n = 2231) retrieved from three clinical wards (internal medicine, gynecology/obstetrics and surgery) in Tikur Anbessa Specialized Hospital (TASH) in Addis Ababa between September 2013 and September 2014...
May 3, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29722891/management-of-crohn-s-disease-and-complications-in-patients-with-ostomies
#18
Xinying Wang, Bo Shen
Fecal diversion with ostomy construction can be a temporary or definitive surgical measure for the treatment of refractory inflammatory bowel disease (IBD). However, the fecal diversion surgery is associated with various stoma, peristomal complications, and recurrence or occurrence of de novo small bowel Crohn's disease (CD). Stoma complications often need enterostomal therapy or surgical revision. Peristomal cutaneous lesions, such as pyoderma gangrenosum, usually require immunomodulator or biological therapy...
May 2, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29720238/two-versus-five-days-of-antibiotics-after-appendectomy-for-complex-acute-appendicitis-appic-study-protocol-for-a-randomized-controlled-trial
#19
Anne Loes van den Boom, Elisabeth M L de Wijkerslooth, Joost van Rosmalen, Frédérique H Beverdam, Evert-Jan G Boerma, Marja A Boermeester, Joanna W A M Bosmans, Thijs A Burghgraef, Esther C J Consten, Imro Dawson, Jan Willem T Dekker, Marloes Emous, Anna A W van Geloven, Peter M N Y H Go, Luc A Heijnen, Sander A Huisman, Dayanara Jean Pierre, Joske de Jonge, Jurian H Kloeze, Marc A Koopmanschap, Hester R Langeveld, Misha D P Luyer, Damian C Melles, Johan W Mouton, Augustinus P T van der Ploeg, Floris B Poelmann, Jeroen E H Ponten, Charles C van Rossem, Wilhelmina H Schreurs, Joël Shapiro, Pascal Steenvoorde, Boudewijn R Toorenvliet, Joost Verhelst, Hendt P Versteegh, Rene M H Wijnen, Bas P L Wijnhoven
BACKGROUND: Acute appendicitis is one of the most common indications for emergency surgery. In patients with a complex appendicitis, prolonged antibiotic prophylaxis is recommended after appendectomy. There is no consensus regarding the optimum duration of antibiotics. Guidelines propose 3 to 7 days of treatment, but shorter courses may be as effective in the prevention of infectious complications. At the same time, the global issue of increasing antimicrobial resistance urges for optimization of antibiotic strategies...
May 2, 2018: Trials
https://www.readbyqxmd.com/read/29719833/a-survey-of-enhanced-recovery-after-surgery-protocols-for-cesarean-delivery-in-serbia
#20
Borislava Pujic, Mirjana Kendrisic, Matthew Shotwell, Yaping Shi, Curtis L Baysinger
Enhanced recovery after surgery (ERAS) protocols have been described for patients undergoing colon surgery. Similar protocols for cesarean delivery (CD) have been developed recently. CD is one of the most commonly performed surgical procedures, and adoption of ERAS protocols following CD might benefit patients and the health-care system. We aimed to determine which Serbian hospitals reported ERAS protocols, which elements of ERAS protocols were used in CD patients, and whether ERAS and non-ERAS hospitals differed...
2018: Frontiers in Medicine
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