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Depression

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https://www.readbyqxmd.com/read/29031217/quality-of-life-and-burden-in-caregivers-of-youth-with-obsessive-compulsive-disorder-presenting-for-intensive-treatment
#1
Monica S Wu, Rebecca Hamblin, Joshua Nadeau, Jessica Simmons, Ashley Smith, Meredith Wilson, Stephanie Eken, Brent Small, Vicky Phares, Eric A Storch
BACKGROUND: Pediatric obsessive-compulsive disorder (OCD) is associated with deleterious familial effects; caregivers are often enmeshed in the disorder and can experience considerable burden and decreased quality of life (QoL). Consequently, this study examined burden and QoL in caregivers of youth with OCD enrolled in an intensive outpatient or partial hospitalization program. METHOD: The relationships between caregiver QoL and burden and the following variables were investigated: OCD symptom severity, functioning (youth functional impairment, general family functioning), family (family accommodation, parental relationship satisfaction, positive aspects of caregiving), and comorbid psychopathology (caregiver anxiety and depressive symptoms, youth internalizing and externalizing behaviors)...
August 30, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29031186/family-functioning-as-perceived-by-parents-and-young-offspring-at-high-and-low-risk-for-depression
#2
Shimrit Daches, Vera Vine, Kathryn M Layendecker, Charles J George, Maria Kovacs
BACKGROUND: Family dysfunction has been proposed as one of the environmental mechanisms whereby risk of depression is transmitted from mothers to their children. Using our sample of offspring at high and low familial risk for depression, we hypothesized that: a) high-risk offspring (n = 79) and their mothers will report more extensive family dysfunction than low-risk offspring (n = 82) and their mothers, b) family dysfunction will predict the extent of offspring's depressive symptoms, and c) family dysfunction will mediate the impact of mother's depression on offspring's depressive symptoms...
September 24, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29031185/diet-quality-and-depression-risk-a-systematic-review-and-dose-response-meta-analysis-of-prospective-studies
#3
REVIEW
Marc Molendijk, Patricio Molero, Felipe Ortuño Sánchez-Pedreño, Willem Van der Does, Miguel Angel Martínez-González
BACKGROUND: It has been claimed that the quality of a diet is associated with the incidence of depressive disorders. We sought to investigate the evidence for this claim. METHODS: Systematic searches were performed up to March 6th, 2017 in order to identify prospective cohort studies that reported on exposure to dietary patterns or food groups and the incidence of depression/depressive symptoms. Data from 24 independent cohorts (totalling 1,959,217 person-years) were pooled in random-effects meta-analyses...
September 23, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29031184/gene-environment-interactions-between-stress-and-5-httlpr-in-depression-a-meta-analytic-update
#4
REVIEW
Dries Bleys, Patrick Luyten, Bart Soenens, Stephan Claes
BACKGROUND: Meta-analyses have yielded contradictory findings concerning the role of 5-HTTLPR in interaction with stress (GxE) in depression. The current meta-analysis investigates if these contradictory findings are a result of differences between studies in methodological approaches towards the assessment of stress and depression. METHODS: After performing a systematic database search (February to December 2016), first, a meta-analysis was used to investigate the total effect size and publication bias...
October 3, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29031183/childhood-hunger-and-depressive-symptoms-in-adulthood-findings-from-a-population-based-study
#5
Andrew Stickley, Mall Leinsalu
BACKGROUND: Several studies have linked childhood hunger to an increased risk for later depression. However, as yet, there has been little research on this relation in adults of all ages or whether there are sex differences in this association. The current study examined these issues using data from a national population-based sample. METHODS: Data were analyzed from 5095 adults aged 25-84 collected during the Estonian Health Interview Survey 2006. Information was obtained on the frequency of going to bed hungry in childhood and on depressive symptoms using the Emotional State Questionnaire (EST-Q)...
September 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29031182/translating-the-ham-d-into-the-madrs-and-vice-versa-with-equipercentile-linking
#6
Stefan Leucht, Hein Fennema, Rolf R Engel, Marion Kaspers-Janssen, Armin Szegedi
BACKGROUND: The Hamilton Depression Rating Scale (HAM-D) and the Montgomery Asberg Depression Rating Scale (MADRS) are scales used frequently to rate the symptoms of depression. There are many situations in which it is important to know what a given total score or a percent reduction from baseline score of one scale means in relation to the other scale. METHOD: We used the equipercentile linking method to identify corresponding scores of simultaneous HAM-D and MADRS ratings in 4388 patients from 31 mirtazapine trials in major depressive disorder...
September 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29031167/impaired-central-coherence-in-patients-with-anorexia-nervosa
#7
Sayo Hamatani, Masahito Tomotake, Tomoya Takeda, Naomi Kameoka, Masashi Kawabata, Hiroko Kubo, Masashi Ohta, Yukio Tada, Yukiko Tomioka, Shinya Watanabe, Masatoshi Inoshita, Makoto Kinoshita, Tetsuro Ohmori
The purpose of this study was to investigate the characteristics of central coherence in patients with anorexia nervosa (AN). 22 female patients with AN (median age = 31.50 (QD = 8.13) years) and 33 female healthy controls (HC) (median age = 28.00 (QD = 8.50) years) participated in the study. Their central coherence was assessed with the Rey Complex Figure Task (RCFT). Clinical symptoms were evaluated with the Beck Depression Inventory-II and the State-Trait Anxiety Inventory-Form JYZ. The results showed that AN patients' Central Coherence Index and accuracy scores in copy, 3-min delayed recall and 30-min delayed recall tasks of the RCFT were significantly lower than those of HC...
September 30, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29031144/senegenin-exerts-anti-depression-effect-in-mice-induced-by-chronic-un-predictable-mild-stress-via-inhibition-of-nf-%C3%AE%C2%BAb-regulating-nlrp3-signal-pathway
#8
Hongwei Li, Shiyi Lin, Tingting Qin, Hongyan Li, Zhanqiang Ma, Shiping Ma
Depressive disorder is a kind of affective disturbance disease. Emerging evidence has suggested that inflammation may contribute to the pathologic process of depressive disorder. Senegenin (SEN), a major bioactive constituent in Polygala tenuifolia Willd, has much bioactivity including anti-inflammatory and neuroprotection effects. However, the mechanism of its anti-depressant effect in mice remains unknown. This study aimed to explore the anti-depressant effects of SEN on behavioral changes and inflammatory responses in mice induced by chronic un-predictable mild stress (CUMS)...
October 11, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/29031131/depression-sleep-problems-and-perceived-stress-among-informal-caregivers-in-58-low-middle-and-high-income-countries-a-cross-sectional-analysis-of-community-based-surveys
#9
Ai Koyanagi, Jordan E DeVylder, Brendon Stubbs, André F Carvalho, Nicola Veronese, Josep M Haro, Ziggi I Santini
Caregiving has been associated with adverse health outcomes. However, there is a paucity of multi-country, population-based studies on mental health outcomes of caregivers especially from low- and middle-income countries (LMICs). Thus, we assessed the association of caregiving with depression, sleep problems, and perceived stress in 10 high-, 27 middle-, and 21 low-income countries. Cross-sectional community-based data of the World Health Survey including 258,793 adults aged ≥18 years were analyzed. Multivariable logistic and linear regression analyses were conducted to explore the association of past 12-month caregiving with past 12-month DSM-IV depression, and past 30-day perceived stress [range 0 (low)-100 (high)] and severe/extreme sleep problems...
October 5, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29031084/moving-towards-the-benign-automatic-interpretation-bias-modification-in-dysphoria
#10
Alexandra H Cowden Hindash, Jonathan A Rottenberg
Automatic cognitive biases are important to theories of depression and reducing such biases may contribute to therapeutic gains. The present study examined (1) whether it was possible to reduce automatic interpretation biases (AIB) in a single session among dysphoric subjects and (2) whether the effects of modifying AIB generalized to other measures of cognition and emotion. 76 dysphoric students completed a modified semantic association paradigm in which they were randomized to receive active or random-feedback-based training...
September 21, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29029215/child-sexual-abuse-and-depression-in-late-life-for-men-a-population-based-longitudinal-analysis
#11
Scott D Easton, Jooyoung Kong, Matt C Gregas, Ce Shen, Kevin Shafer
Objective: Research investigating long-term effects of childhood sexual abuse (CSA) on mental health for men is vastly underdeveloped. This study strengthened the knowledge base by examining: (a) long-term trajectories of depressive symptoms for men with and without a history of CSA, and (b) moderating effects of social support over time. Method: We analyzed multiple waves of data from the Wisconsin Longitudinal Study. The sample (N = 2,451) consisted of men with histories of CSA and a stratified, randomly sampled comparison group...
September 27, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29029169/a-family-affair-family-typologies-of-problems-and-midlife-well-being
#12
Karen L Fingerman, Meng Huo, Jamie L Graham, Kyungmin Kim, Kira S Birditt
Background and Objectives: Midlife adults are a "pivot" generation, responding to parents' and grown children's problems. Yet, some midlife adults may have families where multiple members suffer sorrows, whereas other midlife adults may have families with few problems. This study examined: (a) typologies of problems across generations and (b) associations between profiles of problems and midlife adults' well-being. Research Design and Methods: Midlife adults (N = 633) reported their own, each parent's (n = 868), and grown child's (n = 1,785) physical (e...
September 23, 2017: Gerontologist
https://www.readbyqxmd.com/read/29029015/an-experimental-study-comparing-the-respiratory-effects-of-tapentadol-and-oxycodone-in-healthy-volunteers
#13
R van der Schrier, K Jonkman, M van Velzen, E Olofsen, A M Drewes, A Dahan, M Niesters
Background: There is a clinical need for potent opioids that produce little or no respiratory depression. In the current study we compared the respiratory effects of tapentadol, a mu-opioid receptor agonist and noradrenaline reuptake inhibitor, and oxycodone, a selective mu-opioid receptor agonist. We hypothesize that tapentadol 100 mg has a lesser effect on the control of breathing than oxycodone 20 mg. Methods: Fifteen healthy volunteers were randomized to receive oral tapentadol (100 and 150 mg), oxycodone 20 mg or placebo immediate release tablets in a crossover double-blind randomized design...
October 4, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29028996/cold-tolerance-of-megacopta-cribraria-hemiptera-plataspidae-an-invasive-pest-of-soybeans
#14
Jessica I Grant, William O Lamp
Kudzu bug, Megacopta cribraria Fabricius (Hemiptera: Plataspidae), first discovered in the United States in 2009, is an invasive pest of soybeans. From 2013 to 2016, Maryland has been the northern limit of its distribution in the United States. We sought to determine the physiological cold temperature limits, timing of movement to overwintering locations, and to characterize overwintering microhabitat temperature. We measured supercooling point (SCP) on three populations from distinct USDA plant hardiness zones in Maryland and Virginia between October and December of 2015...
September 23, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/29028908/negative-affect-is-associated-with-higher-risk-of-incident-cognitive-impairment-in-nondepressed-postmenopausal-women
#15
Laura E Korthauer, Joseph Goveas, Mark A Espeland, Sally A Shumaker, Katelyn R Garcia, Hilary Tindle, Elena Salmoirago-Blotcher, Kaycee M Sink, Leslie Vaughan, Stephen R Rapp, Susan M Resnick, Ira Driscoll
BACKGROUND: Positive affect (PA) and negative affect (NA) reflect subjective emotional experiences. Although related to depression and anxiety, these dimensions are distinct constructs representing affective states and patterns. Prior studies suggest that elevated depressive symptoms are associated with risk of mild cognitive impairment (MCI) and probable dementia, but whether affective states are associated with cognitive impairment is still unknown. The present study examined relationships between baseline affective states and cognitive impairment (MCI, probable dementia) in non-depressed women...
September 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29028834/validation-of-a-theoretically-motivated-approach-to-measuring-childhood-socioeconomic-circumstances-in-the-health-and-retirement-study
#16
Anusha M Vable, Paola Gilsanz, Thu T Nguyen, Ichiro Kawachi, M Maria Glymour
Childhood socioeconomic status (cSES) is a powerful predictor of adult health, but its operationalization and measurement varies across studies. Using Health and Retirement Study data (HRS, which is nationally representative of community-residing United States adults aged 50+ years), we specified theoretically-motivated cSES measures, evaluated their reliability and validity, and compared their performance to other cSES indices. HRS respondent data (N = 31,169, interviewed 1992-2010) were used to construct a cSES index reflecting childhood social capital (cSC), childhood financial capital (cFC), and childhood human capital (cHC), using retrospective reports from when the respondent was <16 years (at least 34 years prior)...
2017: PloS One
https://www.readbyqxmd.com/read/29028778/essential-oils-and-gastroparesis-power-for-transforming-health-hope-and-quality-of-life
#17
Chalyce Macoskey, Dorothy J Dunn
This study explored how essential oils for persons with gastroparesis symptoms affect the quality of life. Gastroparesis is a chronic delayed gastric motility disorder characterized by postprandial fullness, early satiety, nausea, vomiting, abdominal discomfort, bloating, depression, and anxiety. The aim of this study was to determine how essential oils support digestion and eliminate inflammation in the body as evidenced by self-reporting a decrease in symptoms, thereby improving quality of life. A qualitative descriptive methodology using Barrette's Theory of Power as Knowing Participation in Change thematic framework was used...
November 2017: Holistic Nursing Practice
https://www.readbyqxmd.com/read/29028757/patient-experience-based-value-sets-are-they-stable
#18
A Simon Pickard, Yu-Ting Hung, Fang-Ju Lin, Todd A Lee
BACKGROUND: Although societal preference weights are desirable to inform resource-allocation decision-making, patient experienced health state-based value sets can be useful for clinical decision-making, but context may matter. OBJECTIVE: To estimate EQ-5D value sets using visual analog scale (VAS) ratings for patients undergoing knee replacement surgery and compare the estimates before and after surgery. METHODS: We used the Patient Reported Outcome Measures data collected by the UK National Health Service on patients undergoing knee replacement from 2009 to 2012...
November 2017: Medical Care
https://www.readbyqxmd.com/read/29028735/inflammatory-bowel-disease-the-hospital-anxiety-and-depression-scale-and-criterion-contamination
#19
Christopher W P Hopkins
No abstract text is available yet for this article.
October 11, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29028692/the-relationship-of-anxiety-depression-and-quality-of-life-in-adults-with-left-ventricular-assist-devices
#20
Jesus M Casida, Martha Abshire, Bidisha Ghosh, James Y Yang
Psychological distress, including anxiety and depression, is commonly reported by patients with implantable left ventricular assist devices (LVADs). Still, the influence of anxiety and depression on global quality of life (QOL) is unknown. Moreover, the empirical data of LVAD patients' QOL is limited to 24 months. This study examined the differences in anxiety, depression, and QOL based on 3 LVAD implant duration groups (≤12, 13-24, and ≥25 months). We also examined the influence of anxiety and depression on QOL...
October 7, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
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