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https://www.readbyqxmd.com/read/28905239/expression-and-distribution-of-three-transient-receptor-potential-vanilloid-trpv-channel-proteins-in-human-odontoblast-like-cells
#1
Wen Wen, Kehua Que, Chengcheng Zang, Jing Wen, Guangxu Sun, Zhiying Zhao, Yanzhong Li
Odontoblasts have been suggested to contribute to nociceptive sensation in the tooth via expression of the transient receptor potential (TRP) channels. The TRP channels as a family of nonselective cation permeable channels play an important role in sensory transduction of human. In this study, we examined the expression of transient receptor potential vanilloid-1 (TRPV1), transient receptor potential vanilloid-2 (TRPV2) and transient receptor potential vanilloid-3 (TRPV3) channels in native human odontoblasts (HODs) and long-term cultured human dental pulp cells with odontoblast phenotyoe (LHOPs) obtained from healthy wisdom teeth with the use of immunohistochemistry (IHC), immunofluorescence (IF), quantitative real-time polymerase chain reaction (qRT-PCR),western blotting (WB) and immunoelectron microscopy (IEM) assay...
September 13, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/28880060/comparison-of-orthopantomography-opg-and-computed-tomography-ct-accuracy-in-predicting-inferior-alveolar-nerve-injury-following-lower-third-molar-surgical-extraction
#2
Fulvio Fusaro, Fulvia Costantinides, Michele Maglione, Domenico Dalessadri, Erica Vettori, Roberto DI Lenarda
BACKGROUND: The aim of this study was to compare OPG and CT accuracy in predicting inferior alveolar nerve (IAN) injury after lower wisdom teeth extraction. METHODS: 23 patients with completely impacted lower third molar were enrolled in this study and OPG and CT exams were obtained before surgical intervention. Finally, a total of 26 lower third molars were extracted and cases of paresthesia following a IAN lesion have been registered. Then, OPG and CT images of the same patients have been randomly submitted to four experienced oral surgeons (with a seniority of at least 5 years) who were required to predict the possibility of a IAN injury by only evaluating the radiological exams...
September 5, 2017: Minerva Stomatologica
https://www.readbyqxmd.com/read/28736906/dental-pulp-stem-cells-and-the-management-of-neurological-diseases-an-update
#3
REVIEW
Ibrahim Mortada, Rola Mortada, Mohamad Al Bazzal
Medical research in regenerative medicine has brought promising perspectives for the use of stem cells in clinical trials. Stem cells are undifferentiated cells capable of multilineage differentiation and available in numerous sources in the human body. Dental pulp constitutes an attractive source of these cells since collecting mesenchymal stem cells from this site is a noninvasive practice that can be performed after a common surgical extraction of supernumerary or wisdom teeth. Thus, tissue sacrifice is very low and several cytotypes can be obtained owing to these cells' multipotency, in addition to the fact that they can be cryopreserved and stored for long periods...
July 24, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/28687960/dental-pulp-stem-cells-and-neurogenesis
#4
Ibrahim Mortada, Rola Mortada, Mohamad Al Bazzal
Recent advances in regenerative medicine and cell-based therapy are bringing promising perspectives for the use of stem cells in clinical trials. Stem cells are undifferentiated cells capable of multilineage differentiation and available in numerous sources in the human body. Dental pulp constitutes an attractive source of these cells since collecting mesenchymal stem cells from this site is a noninvasive procedure which can be done following a common surgical extraction of supernumerary or wisdom teeth. Thus tissue sacrifice is very low and several cytotypes can be obtained owing to these cells' multipotency, in addition to the fact that they can be cryopreserved and stored for long periods...
July 8, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28657463/transplantation-of-human-dental-pulp-derived-stem-cells-or-differentiated-neuronal-cells-from-human-dental-pulp-derived-stem-cells-identically-enhances-regeneration-of-the-injured-peripheral-nerve
#5
Imran Ullah, Ju-Mi Park, Young-Hoon Kang, June-Ho Byun, Dae-Geon Kim, Joo-Heon Kim, Dong-Ho Kang, Gyu-Jin Rho, Bong-Wook Park
Human dental mesenchymal stem cells isolated from the dental follicle, pulp, and root apical papilla of extracted wisdom teeth have been known to exhibit successful and potent neurogenic differentiation capacity. In particular, human dental pulp-derived stem cells (hDPSCs) stand out as the most prominent source for in vitro neuronal differentiation. In this study, to evaluate the in vivo peripheral nerve regeneration potential of hDPSCs and differentiated neuronal cells from DPSCs (DF-DPSCs), a total of 1 × 10(6) hDPSCs or DF-hDPSCs labeled with PKH26 tracking dye and supplemented with fibrin glue scaffold and collagen tubulization were transplanted into the sciatic nerve resection (5-mm gap) of rat models...
July 25, 2017: Stem Cells and Development
https://www.readbyqxmd.com/read/28635381/provoked-eagle-syndrome-after-dental-procedure-a-review-of-the-literature
#6
Shuo Li, Neeraj Blatt, Jubin Jacob, Nishant Gupta, Yogesh Kumar, Scott Smith
Eagle syndrome is an uncommon condition caused by an elongated ossified styloid process. The majority of individuals with an elongated ossified styloid process are asymptomatic. Therefore, this condition is diagnosed based on clinical presentation, with radiologic imaging serving to confirm the diagnosis. The styloid process is considered elongated if measuring greater than 3 cm, but there is little correlation between length of the styloid process and severity of symptoms. This syndrome was originally described in post-tonsillectomy patients, but has since been seen in other clinical settings...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28604375/retained-upper-third-molars-during-le-fort-i-osteotomy-with-downfracture
#7
Marco Friscia, Marzia Petrocelli, Carolina Sbordone, Raffaele Corvino, Fabio Maglitto, Francesco Maria Cassandro, Giorgio Iaconetta, Luigi Califano
AIM: The aim of our study is to demonstrate that the presence of upper wisdom teeth must be evaluated before and during Le Fort I osteotomy because attention must be focused to the disadvantages or facilitations of surgery depending on molar presence. MATERIALS OF STUDY: Our study has analyzed two groups, each one including 20 patients, 10 males and 10 females, with an age between 16-30 years. The first group was treated with le Fort I osteotomy leaving in situ the wisdom upper third molars...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28593907/opioid-induced-hyponatremia-in-a-patient-with-central-diabetes-insipidus-independence-from-adh
#8
Nandini Bhat, Erjola Balliu, Jennifer Osipoff, Andrew Lane, Thomas Wilson
Hyponatremia can be a complication of opioid therapy, which has been postulated to occur secondary to inappropriate antidiuretic hormone secretion (syndrome of inappropriate antidiuretic hormone secretion [SIADH]). We report severe hyponatremia following wisdom teeth extraction with opioid analgesia in a 19-year-old female with diabetes insipidus (DI) and acquired panhypopituitarism that challenges this theory. As this patient has DI, we believe opioid treatment caused severe hyponatremia by the following mechanisms: (1) Opioids have a direct antidiuretic effect independent of changes in ADH, as demonstrated in Brattleboro rats with central DI...
May 24, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28567142/clinical-analysis-of-analgesics-and-steroids-use-for-extraction-of-teeth-in-patients-with-intellectual-disability-under-general-anesthesia
#9
Shigeru Maeda, Yuka Honda, Hiroshi Tanimura, Yumiko Tomoyasu, Hitoshi Higuchi, Naomichi Murata, Masahiko Egusa, Takuya Miyawaki
BACKGROUND: The extraction of lower wisdom teeth is often performed under general anesthesia in patients with intellectual disabilities. However, the choice of analgesics has not yet been investigated. OBJECTIVE: To analyze the use of analgesics during general anesthesia for extraction including lower wisdom teeth in patients with intellectual disabilities. METHODS: This research is a retrospective observational study. The study population was composed of all patients presenting for extraction of lower wisdom teeth under ambulatory general anesthesia in the clinic of Special Needs Dentistry in Okayama University Hospital from April 2011 to March 2016...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28541393/adrenomedullin-promotes-the-odontogenic-differentiation-of-dental-pulp-stem-cells-through-creb-bmp2-signaling-pathway
#10
Qiang Zhu, Jianyong Gao, Gang Tian, Zhen Tang, Yinghui Tan
Adrenomedullin (AM) could promote the proliferation, the odontogenic differentiation and inhibit the apoptosis of dental pulp stem cells (DPSCs). AM in combination with DPSCs may be an effective strategy for pulp repair. However, there was no report on the mechanisms of AM in the odontogenic differentiation of DPSCs. The aim of this study is to investigate the molecular mechanisms through which AM promotes the odontogenic differentiation of DPSCs. Freshly extracted wisdom teeth were obtained from 27 patients...
July 1, 2017: Acta Biochimica et Biophysica Sinica
https://www.readbyqxmd.com/read/28525303/low-level-laser-therapy-after-wisdom-teeth-surgery-evaluation-of-immunologic-markers-secretory-immunoglobulin-a-and-lysozyme-levels-and-thermographic-examination-placebo-controlled-study
#11
Tatjana Dostalova, Veronika Kroulikova, Stepan Podzimek, Helena Jelinková
OBJECTIVE: The goal of this investigation is to analyze the effect of therapeutic low-level laser therapy (LLLT) to have a possibility to check pain and inflammation connected with surgical removal of impacted lower third molars in general anesthesia or even phobia [not accompanied by pain or fear of dental treatment, using immunologic markers-secretory immunoglobulin A (sIgA) and lysozyme]. The healing process was also monitored by infrared thermography. BACKGROUND DATA: LLLT can accelerate the proliferation phase of healing and decrease the inflammatory reaction, but the effect is not really clear...
May 16, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28498604/postoperative-interventions-to-reduce-inflammatory-complications-after-third-molar-surgery-review-of-the-current-evidence
#12
REVIEW
H Cho, A J Lynham, E Hsu
Inflammatory complications such as pain, swelling, trismus, infection and alveolar osteitis have an adverse affect on the quality of life of patients after third molar removal. This review presents the current evidence on postoperative strategies to reduce these complications. A literature search was performed to identify articles published in English between 2000 to 2016 using the following keywords: third molar(s), wisdom tooth/teeth, pain, swelling, trismus, infection, alveolar osteitis and dry socket. In total, 221 papers were reviewed...
May 12, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28453949/replacing-heavily-damaged-teeth-by-third-molar-autotransplantation-with-the-use-of-cone-beam-computed-tomography-and-rapid-prototyping
#13
Jop P Verweij, David Anssari Moin, Daniel Wismeijer, J P Richard van Merkesteyn
This article describes the autotransplantation of third molars to replace heavily damaged premolars and molars. Specifically, this article reports on the use of preoperative cone-beam computed tomographic planning and 3-dimensional (3D) printed replicas of donor teeth to prepare artificial tooth sockets. In the present case, an 18-year-old patient underwent autotransplantation of 3 third molars to replace 1 premolar and 2 molars that were heavily damaged after trauma. Approximately 1 year after the traumatic incident, autotransplantation with the help of 3D planning and rapid prototyping was performed...
September 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28372881/compliance-of-referral-and-hospital-documentation-with-national-institute-of-health-and-care-excellence-guidelines-for-the-extraction-of-third-molars-a-comparative-analysis-of-two-nhs-trusts
#14
D G Gray, J L Franklin, M K Nicholls, K A Eaton, A W Barrett
To find out whether documentation for the extraction of wisdom teeth complies with National Institute of Health and Care Excellence (NICE) guidelines, we reviewed the referral letters and hospital notes of patients treated at the maxillofacial unit of two NHS Trusts (A: 314 records and B: 280) over 12 months (1 September 2012 to 31 August 2013). Compliance was assessed as unsatisfactory ("indication for extraction not mentioned", "incorrect indication", "indication unclear") or satisfactory ("correct indication implied", "correct indication explicit")...
July 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28343833/-consequences-of-impacted-wisdom-teeth-extraction-on-the-periodontal-environment-of-second-molars-a-pilot-study
#15
R Martin, A Louvrier, E Weber, B Chatelain, C Meyer
INTRODUCTION: Wisdom teeth extraction is a common procedure, generally considered as safe by patients. However, complications are possible, especially periodontal ones. The aim of this study was to evaluate the frequency and the consequences of periodontal complications at the level the 2nd molars after extraction of the wisdom teeth. MATERIAL AND METHODS: A single-center retrospective observational multi-operator study was conducted at the university hospital of Besançon - France...
April 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28316922/miracle-cells-for-natural-dentistry-a-review
#16
REVIEW
Rani Somani, Shipra Jaidka, Neeti Bajaj, Sameksha Arora
Stem cells are undifferentiated cells that can differentiate into specialized cells. Recently, enormous growth has been seen in the recognition of stem cell-based therapies, which have the potential to ameliorate the life of patients with conditions that span from Parkinson's disease to cardiac ischemia to bone or tooth loss. This research has produced new but unexplored possibilities in the regeneration of different organs and tissues. Presently, research is focused on the proficiency of stem cells and their utilization in dentistry, which is gaining interest...
January 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28261914/corrigendum-perioperative-bromelain-therapy-after-wisdom-teeth-extraction-a-randomized-placebo-controlled-double-blinded-three-armed-cross-over-dose-finding-study
#17
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28205161/bilateral-supplemental-maxillary-central-incisors-with-double-tooth-like-appearance
#18
R P Anthonappa, S Sudhakar, N M King
BACKGROUND: Supplemental teeth refer to extra teeth that resemble the normal tooth series. Bilateral supplemental central incisors in a healthy individual are rare and bilateral supplemental incisors with double-tooth like appearance are exceptionally rare and has not been previously reported in the dental literature. CASE REPORT: This clinical report describes an 8-year old healthy Indian boy referred for the management of delayed eruption of his permanent maxillary incisor teeth...
February 15, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28166063/eruption-pattern-of-dentition-and-its-medico-legal-significance
#19
R K Karki
Background The eruption pattern of temporary and permanent teeth are fairly constant with the growing age. So the age determination of an individual by examination of teeth is one of the accepted methods in legal system. A review of the literature shows there are differences in eruption pattern between different populations mainly due to variations in the constitutions and environment, so highlighting the importance of this study to the Nepalese population. Objective To assess the eruption age of temporary and permanent teeth in Nepalese population and compared the eruption age with other groups...
April 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/28097682/evaluation-of-perforated-demineralized-dentin-scaffold-on-bone-regeneration-in-critical-size-sheep-iliac-defects
#20
Md Arafat Kabir, Masaru Murata, Toshiyuki Akazawa, Kaoru Kusano, Katsuhisa Yamada, Manabu Ito
OBJECTIVES: Regenerating critical-size bone injury is a major problem that continues to inspire the design of new graft materials. Therefore, tissue engineering has become a novel approach for targeting bone regeneration applications. Human teeth are a rich source of stem cells, matrix, trace metal ions, and growth factors. A vital tooth-derived demineralized dentin matrix is acid-insoluble and composed of cross-linked collagen with growth factors. In this study, we recycled human non-functional tooth into a unique geometric dentin scaffold, entitled perforated root-demineralized dentin matrix (PR-DDM)...
January 17, 2017: Clinical Oral Implants Research
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