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https://www.readbyqxmd.com/read/29049947/3d-spongy-graphene-modified-screen-printed-sensors-for-the-voltammetric-determination-of-the-narcotic-drug-codeine
#1
Mona A Mohamed, Dalia M El-Gendy, Nashaat Ahmed, Craig E Banks, Nageh K Allam
Adenine-functionalized spongy graphene (FSG) composite, fabricated via a facile and green synthetic method, has been explored as a potential electrocatalyst toward the electroanalytical sensing of codeine phosphate (COD). The synthesized composite is characterized using Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, X-ray powder diffraction, UV-vis absorption spectroscopy, scanning electron microscopy, high resolution transmission electron microscopy (HRTEM), and thermogravimetric analysis...
October 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29049784/hormonal-manipulation-after-surgery-for-catamenial-pneumothorax
#2
Megan Garner, Eltayeb Ahmed, Sarah Gatiss, Douglas West
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was whether hormonal manipulation with gonadotrophin-releasing hormone analogues reduces the risk of recurrent catamenial pneumothorax after surgery, compared with surgery alone. Altogether 819 papers were found using the reported search, of which 7 represented the best evidence to answer the clinical question. The authors, date, journal, country of publication, study type, level of evidence, patient group studied, relevant outcomes and results of these papers are tabulated...
September 28, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049735/clinical-and-biological-evaluations-of-biodegradable-collagen-matrices-for-glaucoma-drainage-device-implantation
#3
Minjung Song, Seunghyun Lee, Deokyeong Choe, Sera Kim, Young Hoon Roh, Seungsoo Rho
Purpose: To characterize the clinical and biological properties of biodegradable collagen matrices (BCMs) for possible glaucoma drainage device implantation. Methods: A total of 68 refractory glaucoma eyes, followed up postoperatively for at least 6 months, were consecutively enrolled after retrospective chart review. The BCM-augmented Ahmed valve implantations (BAAVI) using our Ologen-6 and Ologen-7 valves were performed and compared with a conventional method...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29049702/aortic-root-and-hemiarch-replacement-in-a-patient-with-loeys-dietz-and-hypoplastic-left-heart-syndromes
#4
Eltayeb Mohamed Ahmed, Alexandru Ciprian Visan, Graham Stuart, Serban Stoica
A 15-year-old patient with hypoplastic left heart syndrome underwent 3-stage palliation by the age of 3 years. He was later diagnosed with Loeys-Dietz syndrome. On follow-up imaging, the neoaorta was dilated at 50 mm in diameter. He underwent aortic root replacement with a composite valve conduit and hemiarch replacement, using a boat-shaped Dacron graft. The uncertainty of how univentricular circulation would tolerate long bypass time steered us away from a total arch replacement. His postoperative recovery was uneventful...
October 11, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049537/bilateral-bidirectional-glenn-outcome-of-off-pump-technique
#5
Ashraf A H El Midany, Ezzeldin A Mostafa, Sherif A Mansour, Mohammed Saffan, Mahmoud Zalat, Ismail N El-Sokkary, Ahmed M E Aletreby
OBJECTIVES: Off-pump bilateral bidirectional Glenn (b-BDG) poses a surgical challenge and may add complexity to the postoperative outcome especially regarding uniformity of the anastomosis and central pulmonary artery growth. Herein, we report early- and mid-term outcomes after off-pump b-BDG without using superior vena cava decompression techniques. METHODS: Ninety-seven consecutive patients, between 2009 and 2014, were included in this prospective study. All patients had complete pre- and postoperative clinical and detailed neurological assessments...
June 13, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049516/making-a-case-for-sanctuary-hospitals
#6
Altaf Saadi, Sameer Ahmed, Mitchell H Katz
No abstract text is available yet for this article.
October 16, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29049354/inverse-association-of-marijuana-use-with-nonalcoholic-fatty-liver-disease-among-adults-in-the-united-states
#7
Donghee Kim, Won Kim, Min-Sun Kwak, Goh Eun Chung, Jeong Yoon Yim, Aijaz Ahmed
BACKGROUND & AIMS: The impact of marijuana on nonalcoholic fatty liver disease (NAFLD) is largely unknown. We studied the association between marijuana and NAFLD utilizing cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) from 2005-2014 and NHANES III (1988-1994). METHODS: Suspected NAFLD was diagnosed if serum alanine aminotransferase (ALT) was > 30 IU/L for men and > 19 IU/L for women in the absence of other liver diseases (NHANES 2005-2014)...
2017: PloS One
https://www.readbyqxmd.com/read/29049253/clinical-efficacy-analysis-of-ahmed-glaucoma-valve-implantation-in-neovascular-glaucoma-and-influencing-factors-a-strobe-compliant-article
#8
Ye He, Ying Tian, Weitao Song, Ting Su, Haibo Jiang, Xiaobo Xia
This study aimed to evaluate the efficacy of Ahmed glaucoma valve (AGV) implantation in treating neovascular glaucoma (NVG) and to analyze the factors influencing the surgical success rate.This is a retrospective review of 40 eyes of 40 NVG patients who underwent AGV implantation at Xiangya Hospital of Central South University, China, between January 2014 and December 2016. Pre- and postoperative intraocular pressure (IOP), visual acuity, surgical success rate, medications, and complications were observed. Surgical success criteria were defined as IOP ≤21 and >6 mm Hg with or without additional medications...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29048873/insights-into-mycobacteria-interactions-with-the-host-innate-immune-system-from-a-novel-array-of-synthetic-mycobacterial-glycans
#9
Ruixiang Blake Zheng, Sabine A F Jégouzo, Maju Joe, Yu Bai, Huu-Anh Tran, Ke Shen, Jörn Saupe, Li Xia, Md Faiaz Ahmed, Yu-Hsuan Liu, Pratap Subhashrao Patil, Ashish Tripathi, Shang-Cheng Hung, Maureen E Taylor, Todd L Lowary, Kurt Drickamer
An array of homogenous glycans representing all the major carbohydrate structures present in the cell wall of the human pathogen Mycobacterium tuberculosis and other mycobacteria has been probed with a panel of glycan-binding receptors expressed on cells of the mammalian innate immune system. The results provide an overview of interactions between mycobacterial glycans and receptors that mediate uptake and survival in macrophages, dendritic cells and sinusoidal endothelial cells. A subset of the wide variety of glycan structures present on mycobacterial surfaces interact with cells of the innate immune system through the receptors tested...
October 19, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/29048754/randomized-controlled-trial-of-the-effect-of-endometrial-injury-on-implantation-and-clinical-pregnancy-rates-during-the-first-icsi-cycle
#10
Ahmed M Maged, Hamsa Rashwan, Suzy AbdelAziz, Wafaa Ramadan, Walaa Ai Mostafa, Ahmed A Metwally, Maha Katta
OBJECTIVE: To assess whether endometrial injury in the cycle preceding controlled ovarian hyperstimulation during intracytoplasmic sperm injection (ICSI) improves the implantation and pregnancy rates. METHODS: Between January 1, 2016, and March 31, 2017, a randomized controlled trial was conducted at a center in Egypt among 300 women who met inclusion criteria (first ICSI cycle, aged <40 years, day-3 follicle-stimulating hormone <10 IU/L, normal serum prolactin, no uterine cavity abnormality)...
October 19, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29048556/deep-brain-stimulation-related-infections-analysis-of-rates-timing-and-seasonality
#11
Fran A Hardaway, Ahmed M Raslan, Kim J Burchiel
BACKGROUND: Infection is one of the most common complications of deep brain stimulation (DBS). Long-term infection rates beyond the immediate postoperative period are rarely evaluated. OBJECTIVE: To study short- and long-term DBS-related infection rates; to evaluate any potential seasonality associated with DBS-related infections. METHODS: We retrospectively reviewed all DBS surgeries performed in a 5-yr period at 1 hospital by a single surgeon...
October 18, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29048527/the-evolution-of-dark-matter-in-the-mitogenome-of-seed-beetles
#12
Ahmed Sayadi, Elina Immonen, Christian Tellgren-Roth, Göran Arnqvist
Animal mitogenomes are generally thought of as being economic and optimized for rapid replication and transcription. We use long-read sequencing technology to assemble the remarkable mitogenomes of four species of seed beetles. These are the largest circular mitogenomes ever assembled in insects, ranging from 24,496 to 26,613 bp in total length, and are exceptional in that some 40% consists of non-coding DNA. The size expansion is due to two very long intergenic spacers (LIGSs), rich in tandem repeats. The two LIGSs are present in all species but vary greatly in length (114-10,408 bp), show very low sequence similarity, divergent tandem repeat motifs, a very high AT content and concerted length evolution...
October 1, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29048289/outbreak-of-zika-virus-infections-dominica-2016
#13
Sadie J Ryan, Colin J Carlson, Anna M Stewart-Ibarra, Mercy J Borbor-Cordova, Moory M Romero, Shelly-Ann Cox, Roché Mahon, Adrian Trotman, Sylvester St Ville, Shalauddin Ahmed
In February 2016, the World Health Organization declared the pandemic of Zika virus a public health emergency. On March 4, 2016, Dominica reported its first autochthonous Zika virus disease case; subsequently, 1,263 cases were reported. We describe the outbreak through November 2016, when the last known case was reported.
November 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29048214/validation-of-a-full-immersion-simulation-platform-for-percutaneous-nephrolithotomy-using-3d-printing-technology
#14
Ahmed Ghazi, Timothy Campbell, Rachel Melnyk, Changyong Feng, Alex Andrusco, Jonathan Stone, Erdal Erturk
INTRODUCTION AND OBJECTIVES: The restriction of resident hours with an increasing focus on patient safety and a reduced caseload has impacted surgical training. A complex and complication prone procedure such as percutaneous nephrolithotomy (PCNL) with a steep learning curve may create an unsafe environment for hands-on resident training. In this study, we validate a high fidelity, inanimate PCNL model within a full immersion simulation environment. METHODS: Anatomically correct models of the human pelvicalyceal system (PCS), kidney, and relevant adjacent structures were created using poly-vinyl alcohol (PVA) hydrogels and 3D-printed injection molds...
October 19, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29047909/fiber-integrated-spectroscopy-device-for-hot-alkali-vapor
#15
Josephine Gutekunst, Daniel Weller, Harald Kübler, Jan-Philipp Negel, Marwan Abdou Ahmed, Thomas Graf, Robert Löw
We introduce an all-glass, vacuum tight, fiber-integrated and alkali compatible spectroscopy device consisting of two conventional optical fibers spliced to each end of a capillary. This is mainly realized through a decentered splicing method allowing refilling of the capillary and controlling the vapor density inside. We analyze the light guidance of the setup through simulations and measurements of the transmission efficiency at different wavelengths and show that filling it with highly reactive alkali metals is possible, and that the vapor density can be controlled reliably...
July 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/29047519/dbpsk-and-dqpsk-crosstalk-in-single-span-wdm-systems-using-dra
#16
Emadeldeen Morsy, Heba A Fayed, Ahmed Abd El-Aziz, Moustafa H Aly
A closed-loop formula is derived for the nonlinear crosstalk degradation due to self-phase modulation and cross-phase modulation in a wavelength-division multiplexing system. The crosstalk is investigated in differential binary phase-shift keying (DBPSK) and differential quadrature phase-shift keying (DQPSK) schemes. The system under consideration is standard single-mode fiber with a single-span distributed Raman amplifier. The backward DBPSK shows a better performance with minimum crosstalk performance of 71%, as compared to backward DQPSK...
July 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29047406/loss-of-mkp-5-promotes-myofiber-survival-by-activating-stat3-bcl-2-signaling-during-regenerative-myogenesis
#17
Kisuk Min, Ahmed Lawan, Anton M Bennett
BACKGROUND: The mitogen-activated protein kinases (MAPKs) have been shown to be involved in regulating myofiber survival. In skeletal muscle, p38 MAPK and JNK are negatively regulated by MAPK phosphatase-5 (MKP-5). During muscle regeneration, MKP-5 is downregulated, thereby promoting p38 MAPK/JNK signaling, and subsequent repair of damaged muscle. Mice lacking MKP-5 expression exhibit enhanced regenerative myogenesis. However, the effect of MKP-5 on myofiber survival during regeneration is unclear...
October 18, 2017: Skeletal Muscle
https://www.readbyqxmd.com/read/29046668/characterization-of-anti-bacterial-compounds-from-the-seed-coat-of-chinese-windmill-palm-tree-trachycarpus-fortunei
#18
Shakeel Ahmed, Huimin Liu, Aqeel Ahmad, Waheed Akram, Eman K N Abdelrahman, Fengming Ran, Wuling Ou, Shuang Dong, Qian Cai, Qiyun Zhang, Xiaohua Li, Sheng Hu, Xuebo Hu
The increasing of multidrug resistance in bacterial associated infections has impaired the current antimicrobial therapy and it forces the search for other alternatives. In this study, we aimed to find the in vitro antibacterial activity of seed coat of Trachycarpus fortunei against a panel of clinically important bacterial species. Ethanolic extracts of target tissues were fractionated through macro porous resin by column chromatography, using ethanol as an organic solvent with a concentration gradient of 0-100%, each along with 20% concentration increment...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29046441/structure-function-dissection-of-the-pseudorabies-virus-glycoprotein-b-fusion-loops
#19
Melina Vallbracht, Delphine Brun, Matteo Tassinari, Marie-Christine Vaney, Gérard Pehau-Arnaudet, Pablo Guardado-Calvo, Ahmed Haouz, Barbara G Klupp, Thomas C Mettenleiter, Felix A Rey, Marija Backovic
Conserved across the Herpesviridae family, glycoprotein B (gB) is responsible for driving fusion of the viral envelope with the host cell membrane for entry upon receptor binding and activation by the viral gH/gL complex. Although crystal structures of the gB ectodomain of several herpesviruses have been reported, the membrane fusion mechanism has remained elusive. Here, we report the X-ray structure of the Pseudorabies virus (PrV) gB ectodomain, revealing a typical class III post-fusion trimer that binds membranes via its fusion loops (FLs) in a cholesterol-dependent manner...
October 18, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29046352/the-lignan-manassantin-is-a-potent-and-specific-inhibitor-of-mitochondrial-complex-i-and-bioenergetic-activity-in-mammals
#20
Yibao Ma, Hae-Ki Min, Unsong Oh, Adam M Hawkridge, Wei Wang, Ahmed A Mohsin, Qun Chen, Arun Sanyal, Edward J Lesnefsky, Xianjun Fang
Dineolignans manassantin A and B from the plant Saururus cernuus are used in traditional medicine to manage a wide range of ailments such as edema, jaundice, and gonorrhea. Cell-based studies have identified several molecular target candidates of manassantin including NF-kappaB, MAPK, STAT3 and hypoxia-inducible factor 1 alpha (HIF-1alpha). It is unclear whether or how these structurally diverse proteins or pathways mediate any of the medical benefits of manassantin in vivo. Moreover, it has been recently reported that manassantin causes developmental arrest in zebrafish by inhibiting the mitochondrial complex I, but it is unknown whether manassantin inhibits mitochondrial respiration in intact mammalian cells and live animals...
October 18, 2017: Journal of Biological Chemistry
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