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https://www.readbyqxmd.com/read/29245114/subacromial-impingement-syndrome-an-electromyographic-study-of-shoulder-girdle-muscle-fatigue
#1
Omid Alizadehkhaiyat, Margaret M Roebuck, Ahmed T Makki, Simon P Frostick
Muscle fatigue affecting glenohumeral and/or scapular muscles is suggested as one of the contributing factors to the development of subacromial impingement syndrome (SAIS). Nonetheless, the fatigability of shoulder girdle muscles in association with the pathomechanics of SAIS has not been reported. This study aimed to measure and compare fatigue progression within the shoulder girdle musculature of patients and healthy controls. 75 participants including 39 patients (20 females; 19 males) and 36 healthy controls (15 females; 21 males) participated in the study...
December 7, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29245012/visualizing-the-assembly-pathway-of-nucleolar-pre-60s-ribosomes
#2
Lukas Kater, Matthias Thoms, Clara Barrio-Garcia, Jingdong Cheng, Sherif Ismail, Yasar Luqman Ahmed, Gert Bange, Dieter Kressler, Otto Berninghausen, Irmgard Sinning, Ed Hurt, Roland Beckmann
Eukaryotic 60S ribosomal subunits are comprised of three rRNAs and ∼50 ribosomal proteins. The initial steps of their formation take place in the nucleolus, but, owing to a lack of structural information, this process is poorly understood. Using cryo-EM, we solved structures of early 60S biogenesis intermediates at 3.3 Å to 4.5 Å resolution, thereby providing insights into their sequential folding and assembly pathway. Besides revealing distinct immature rRNA conformations, we map 25 assembly factors in six different assembly states...
December 14, 2017: Cell
https://www.readbyqxmd.com/read/29244902/feasibility-of-predicting-tumor-motion-using-online-data-acquired-during-treatment-and-a-generalized-neural-network-optimized-with-offline-patient-tumor-trajectories
#3
Troy Teo, Syed Bilal Ahmed, Nadia Alayoubi, Neil Bruce, Ethan Lyn, Stephen Pistorius
PURPOSE: The accurate prediction of intra-fraction lung tumor motion is required to compensate for system latency in image-guided adaptive radiotherapy systems. The goal of this study was to identify an optimal prediction model that has a short learning period so that prediction and adaptation can commence soon after treatment begins, and requires minimal re-optimization for individual patients. Specifically, the feasibility of predicting tumor position using a combination of a generalized (i...
December 15, 2017: Medical Physics
https://www.readbyqxmd.com/read/29244266/patients-with-alcohol-use-disorder-co-occurring-with-depression-and-anxiety-symptoms-diagnostic-and-treatment-initiation-recommendations
#4
Ahmed N Hassan
No abstract text is available yet for this article.
December 12, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29244229/transoral-robotic-surgery-for-residual-and-recurrent-oropharyngeal-cancers-exploratory-study-of-surgical-innovation-using-the-ideal-framework-for-early-phase-surgical-studies
#5
Vinidh Paleri, Hannah Fox, Sarah Coward, Maniram Ragbir, Andrew McQueen, Omar Ahmed, David Meikle, Daniel Saleh, James O'Hara, Max Robinson
BACKGROUND: The purpose of this study was to identify the role of transoral robotic surgery (TORS) in the management of residual and recurrent oropharyngeal cancer. METHODS: IDEAL (Idea, Development, Exploration, Assessment, Long-term Follow-up) 2a framework. RESULTS: Of 26 patients assessed for TORS, 21 underwent the procedure, 5 underwent open resection (4 due to unsuitable anatomy/tumor extent and 1 on the basis of patient choice). Three patients underwent intraoperative ultrasound-assisted robotic resection, and 3 received robotic-assisted free flap inset...
December 15, 2017: Head & Neck
https://www.readbyqxmd.com/read/29244212/detection-of-enteric-and-non-enteric-adenoviruses-in-gastroenteritis-patients-bangladesh-2012-2015
#6
Mokibul Hassan Afrad, Tasnuva Avzun, Jahurul Haque, Warda Haque, Mohammad Enayet Hossain, Afm Rajibur Rahman, Shahnawaz Ahmed, Abu Syed Golam Faruque, Mohammed Ziaur Rahman, Mustafizur Rahman
BACKGROUND: Human adenoviruses (HAdVs) are common cause of nonbacterial acute gastroenteritis worldwide. Limited data exist on HAdVs molecular epidemiology associated with acute gastroenteritis in Bangladesh. OBJECTIVE: We describe the genetic diversity and epidemiology of HAdVs among hospitalized diarrhea patients, including HAdV genotypes, clinical symptoms and co-infecting enteric pathogens. STUDY DESIGN: Stool samples were collected from ongoing diarrhea surveillance during 2012-2015...
December 15, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29243941/critical-success-factors-in-implementing-an-e-rostering-system-in-a-healthcare-organisation
#7
Zahoor A Soomro, Javed Ahmed, Raza Muhammad, Dawn Hayes, Mahmood H Shah
Effective and efficient staff scheduling has always been a challenging issue, especially in health service organisations. Both the extremes of staff shortage and overage have an adverse impact on the performance of healthcare organisations. In this case, an electronic and systematic staff scheduling (e-rostering) system is the often seen as the best solution. Unless an organisation has an effective implementation of such a system, possible cost savings, efficiency, and benefits could be minimal. This study is aimed to research key success factors for the successful effective implementation of an electronic rostering system, especially at healthcare organisations...
January 1, 2017: Health Services Management Research
https://www.readbyqxmd.com/read/29243845/fc%C3%AE%C2%B5r1%C3%AE-gene-polymorphism-shows-association-with-high-ige-and-anti-fc%C3%AE%C2%B5r1%C3%AE-in-chronic-rhinosinusitis-with-nasal-polyposis
#8
Sajad Ahmad Dar, Gargi Rai, Mohammad Ahmed Ansari, Naseem Akhter, Neelima Gupta, Sonal Sharma, Shafiul Haque, Vishnampettai Ganapathysubramanian Ramachandran, Mohd Wahid, M Rudramurthy Shivprakash, Arunaloke Chakrabarti, Shukla Das
Despite large number of investigations, the etiology of chronic rhinosinusitis (CRS) remains unclear. Several factors are likely involved in its onset. The genetic susceptibility of IgE-responsiveness likely caused by polymorphism(s) in high affinity receptor for IgE (FcεR1α) gene can help in understanding the pathophysiology of CRS with nasal polyposis (CRSwNP). A population-based case-control association analysis was conducted to assess the risk of CRSwNP conferred by single nucleotide polymorphisms (SNPs) in FcεR1α gene in a North Indian cohort...
December 15, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29243754/recycling-of-zincite-zno-via-uptake-of-hydrogen-halides
#9
Oday H Ahmed, Mohammednoor Altarawneh, Mohammad Al-Harahsheh, Zhong-Tao Jiang, Bogdan Z Dlugogorski
Hydrogen halides (HCl/HBr) represent major halogen fragments from the thermal decomposition of halogen laden materials, most notably PVC and brominated flame retardants (BFRs). Co-pyrolysis of halogen-containing solid waste with metal oxides is currently deployed as a mainstream strategy to treat halogen content as well as to recycle the valuable metallic fraction embedded in electric arc furnace dust (EAFD) and e-waste. However, designing an industrial-scale recycling facility necessitates accurate knowledge on mechanistic and thermo-kinetic parameters dictating the interaction between metal oxides and hydrogen halides...
December 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29243149/ferulic-acid-protects-against-radiation-induced-testicular-damage-in-male-rats-impact-on-sirt1-and-parp1
#10
Hala O El-Mesallamy, Rania A Gawish, Al-Aliaa M Sallam, Hanan A Fahmy, Ahmed S Nada
Ionizing radiation is a major contributor to male infertility by destroying spermatogenesis. Therefore, the need for an effective radio-protective agent is evident. The objective of the present study was to investigate the potential radio-protective effect of ferulic acid (FA) on radiation-induced testicular damage. Mature male Sprague-Dawley rats were either exposed to a single-dose gamma radiation (5 Gy) and/or treated with FA (50 mg/kg), daily for 7 days before irradiation. Sirtuin1 (SIRT1), poly (ADP-ribose) polymerase 1 (PARP1), cytosolic calcium content, and the male reproductive functions (sperm head abnormality) as well as oxidative stress markers were assessed 7 days after irradiation...
December 14, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29242974/effect-of-intramural-fibroid-on-uterine-and-endometrial-vascularity-in-infertile-women-scheduled-for-in-vitro-fertilization
#11
Ahmed Kamel, Akmal El-Mazny, Wafaa Ramadan, Suzy Abdelaziz, Sherine Gad-Allah, Hany Saad, Ahmed M Hussein, Emad Salah
PURPOSE: To study the effect of intramural fibroids on uterine and endometrial vascularity in infertile women scheduled for in-vitro fertilization (IVF). METHODS: 3D power Doppler was used to measure the endometrial volume and blood flow indices in 182 women with intramural fibroids not affecting the uterine cavity and compared them to a matched control group without fibroids. RESULTS: There was significantly increased vascularity in the endometrium of the fibroid group as denoted by higher endometrial VI (p = 0...
December 14, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29242736/inguinal-herniation-of-urinary-bladder-on-f-18-sodium-fluoride-naf-pet-ct
#12
Sharjeel Usmani, Fahad Marafi, Najeeb Ahmed, Nafisah Kazem
Inguinal herniation of urinary bladder is uncommon and usually an incidental finding in asymptomatic patients. In some of these patients, residual urine volume and consequently, urinary tracer activity can be higher in the herniated bladder than the native bladder, in which case interpretation can be challenging on conventional planar imaging. We describe an interesting case of physiological activity in a herniated bladder simulating a "tear-drop". This case serves an important reminder that whilst F-18 NaF PET-CT has a similar spectrum of urinary activity to conventional bone scintigraphy; morphological correlation on hybrid imaging is invaluable in ensuring the physiological nature of uptake...
December 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29242444/the-current-status-of-neocnus-arredondo-1961-mammalia-edentata-pilosa-megalonichidae-and-a-replacement-name-for-its-junior-homonym-in-the-sea-cucumber-family-cucumariidae-echinodermata-holothuroidea-dendrochirotida-cucumariidae
#13
Ahmed S Thandar, Lazaro W V Vinola
This short communication addresses the problem associated with the current taxonomic status of the prehistoric edentate genus Neocnus Arredondo, 1961 (with type species Micronocnus gliriformis Matthew, 1931) which has long been considered a senior homonym of the dendrochirotid sea cucumber genus Neocnus Cherbonnier, 1972 (type species Neocnus incubans Cherbonnier, 1972) and replaces the latter (junior homonym) with Incubocnus n.g. The diagnosis of the new genus is the same as the cucumariid Neocnus as amended by O'Loughlin & O'Hara (1992)...
October 17, 2017: Zootaxa
https://www.readbyqxmd.com/read/29242360/imaging-of-anaplastic-thyroid-carcinoma
#14
S Ahmed, M P Ghazarian, M E Cabanillas, M E Zafereo, M D Williams, T Vu, D F Schomer, J M Debnam
Anaplastic thyroid carcinoma is fatal if unresectable. However, improved survival has been reported after gross total resection and multimodality therapy. In this report, we describe the contrast-enhanced high-resolution CT characteristics of anaplastic thyroid carcinoma in 57 patients. Anaplastic thyroid carcinoma presented as a large neck mass with necrosis in 82% of cases. The tumors demonstrated common extrathyroidal extension (91%). Sixty-two percent of tumors demonstrated calcification. Visceral space invasion involved the esophagus (62%), trachea (57%), and larynx (29%)...
December 14, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29242240/persistence-of-infarct-zone-t2-hyperintensity-at-6-months-after-acute-st-segment-elevation-myocardial-infarction-incidence-pathophysiology-and-prognostic-implications
#15
Jaclyn Carberry, David Carrick, Caroline Haig, Nadeem Ahmed, Ify Mordi, Margaret McEntegart, Mark C Petrie, Hany Eteiba, Stuart Hood, Stuart Watkins, Mitchell Lindsay, Andrew Davie, Ahmed Mahrous, Ian Ford, Naveed Sattar, Paul Welsh, Aleksandra Radjenovic, Keith G Oldroyd, Colin Berry
BACKGROUND: The incidence and clinical significance of persistent T2 hyperintensity after acute ST-segment-elevation myocardial infarction (STEMI) is uncertain. METHODS AND RESULTS: Patients who sustained an acute STEMI were enrolled in a cohort study (BHF MR-MI: NCT02072850). Two hundred eighty-three STEMI patients (mean age, 59±12 years; 75% male) had cardiac magnetic resonance with T2 mapping performed at 2 days and 6 months post-STEMI. Persisting T2 hyperintensity was defined as infarct T2 >2 SDs from remote T2 at 6 months...
December 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29242177/implementing-a-mental-health-care-program-and-home-based-training-for-mothers-of-children-with-autism-spectrum-disorder-in-an-urban-population-in-bangladesh-protocol-for-a-feasibility-assessment-study
#16
Aliya Naheed, Kamrun Nahar Koly, Helal Uddin Ahmed, Shaheen Akhter, M M Jalal Uddin, Mary C Smith Fawzi, Subhash Chandir, Muzharul Mannan, Saima Hossain, Charles Nelson, Kerim Munir
BACKGROUND: Mothers of children with autism spectrum disorder (ASD) have reported a higher level of depression than mothers of children with other neurodevelopmental disorders in both developed and developing countries. Mothers are the lifetime caregivers of children with ASD, and a high burden of depression can negatively impact their ability to provide care. However, access to mental health services in primary care is limited, given the scarcity of qualified providers in Bangladesh...
December 14, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29242111/autologous-transplantation-in-follicular-lymphoma-with-early-therapy-failure-a-nlcs-and-cibmtr-analysis
#17
Carla Casulo, Jonathan W Friedberg, Kwang Woo Ahn, Christopher Flowers, Alyssa DiGilio, Sonali M Smith, Sairah Ahmed, David Inwards, Mahmoud Aljurf, Andy I Chen, Hannah Choe, Jonathon Cohen, Edward Copelan, Umar Farooq, Timothy S Fenske, Cesar Freytes, Sameh Gaballa, Siddhartha Ganguly, Yogesh Jethava, Rammurti T Kamble, Vaishalee P Kenkre, Hillard Lazarus, Aleksandr Lazaryan, Richard F Olsson, Andrew R Rezvani, David Rizzieri, Sachiko Seo, Gunjan L Shah, Nina Shah, Melham Solh, Anna Sureda, Basem William, Aaron Cumpston, Andrew D Zelenetz, Brian K Link, Mehdi Hamadani
Patients with follicular lymphoma (FL) experiencing early therapy failure (ETF) within two years of frontline chemoimmunotherapy have poor overall survival (OS). We analyzed data from the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National LymphoCare Study (NLCS) to determine whether autologous hematopoietic cell transplant (autoHCT) can improve outcomes in this high-risk FL subgroup.ETF was defined as failure to achieve at least partial response after frontline chemoimmunotherapy or lymphoma progression within two years of frontline chemoimmunotherapy...
December 11, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29242013/blink-and-you-will-miss-it-an-important-consideration-in-facial-burns
#18
Abdulla Ibrahim, Devvrat Katechia, Ahmed Elfaki, Thomas Cobley, Sankhya Kapil Sen
No abstract text is available yet for this article.
December 11, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29241997/quadrilateral-plate-fractures-of-the-acetabulum-proposition-for-a-novel-classification-system
#19
Walid A ElNahal, Mahmoud Abdel Karim, Sherif A Khaled, Ahmed Hazem Abdelazeem, Hazem Abdelazeem
BACKGROUND: Currently, there is no definition or classification system for quadrilateral plate (QLP) fractures; the aim was to anatomically and radiologically characterise the QLP, propose a definition and classify QLP fractures. METHODS: This study included an anatomical component and a radiological component. The anatomical study aimed at defining the characteristics of the QLP; the QLP was identified using four articulating bony pelvis specimens. A titanium mesh was placed on the specimens' quadrilateral surface; standard anteroposterior and oblique views were obtained, and axial CT images, to determine the radiological landmarks...
December 1, 2017: Injury
https://www.readbyqxmd.com/read/29241979/acalabrutinib-in-relapsed-or-refractory-mantle-cell-lymphoma-ace-ly-004-a-single-arm-multicentre-phase-2-trial
#20
Michael Wang, Simon Rule, Pier Luigi Zinzani, Andre Goy, Olivier Casasnovas, Stephen D Smith, Gandhi Damaj, Jeanette Doorduijn, Thierry Lamy, Franck Morschhauser, Carlos Panizo, Bijal Shah, Andrew Davies, Richard Eek, Jehan Dupuis, Eric Jacobsen, Arnon P Kater, Steven Le Gouill, Lucie Oberic, Taduesz Robak, Todd Covey, Richa Dua, Ahmed Hamdy, Xin Huang, Raquel Izumi, Priti Patel, Wayne Rothbaum, J Greg Slatter, Wojciech Jurczak
BACKGROUND: Bruton tyrosine kinase is a clinically validated target in mantle cell lymphoma. Acalabrutinib (ACP-196) is a highly selective, potent Bruton tyrosine kinase inhibitor developed to minimise off-target activity. METHODS: In this open-label, phase 2 study, oral acalabrutinib (100 mg twice per day) was given to patients with relapsed or refractory mantle cell lymphoma, until disease progression or unacceptable toxicity. The primary endpoint was overall response assessed according to the Lugano classification, and safety analyses were done in all participants...
December 11, 2017: Lancet
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