keyword
https://read.qxmd.com/read/38617942/mortality-risk-factors-in-the-dependent-population-of-castilla-la-mancha-spain-before-and-during-the-first-covid-19-wave
#21
JOURNAL ARTICLE
Isabel Pardo-Garcia, Roberto Martinez-Lacoba, Pablo Moya-Martínez, Elisa Amo-Saus, Raúl Del Pozo-Rubio, Francisco Escribano-Sotos
The coronavirus disease pandemic has had an important impact worldwide. The population aged over 65 years and aged dependent persons are the population groups which have suffered in a highest level the consequences of the pandemic in terms of cases and death. In Spain, the situation is similar to other countries, but regional studies are needed because competencies on long-term care depend on regional public administration. Thus, the aim of this work is to analyse social and individual factors associated with the risk of mortality of legally recognised dependent people during the pandemic compared to a non-pandemic period...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38614457/deductive-care-methodology-describing-and-testing-modes-of-care-research
#22
JOURNAL ARTICLE
José María Santamaría-García, Alexandra González-Aguña, Marta Fernández-Batalla, Sara Herrero-Jaén, María Lourdes Jiménez-Rodríguez, León Atilano González-Sotos
OBJECTIVE: Define the modes of procedure of the Deductive Care Methodology (DCM) in the generation of knowledge about person's health care. METHODOLOGY: Design and test of the DCM modes based on three phases: mapping of the MDC, generation of models from this methodology and testing of the models through studies in a clinical context. RESULTS: The MDC presents five levels of abstraction with three modes broken down to 16 types. The modes are: Philosophical Mode to conceptualize and obtain generalities about reality, Mathematical Mode to operate with generalities, and Physical Mode to operationally verify, validating the results and the predictive capacity of the model...
April 11, 2024: Enfermería clínica (English Edition)
https://read.qxmd.com/read/38614374/sars-cov-2-mitochondrial-metabolic-and-epigenomic-reprogramming-in-covid-19
#23
JOURNAL ARTICLE
Joseph W Guarnieri, Jeffrey A Haltom, Yentli E Soto Albrecht, Timothy Lie, Arnold Z Olali, Gabrielle A Widjaja, Sujata S Ranshing, Alessia Angelin, Deborah Murdock, Douglas C Wallace
To determine the effects of SARS-CoV-2 infection on cellular metabolism, we conducted an exhaustive survey of the cellular metabolic pathways modulated by SARS-CoV-2 infection and confirmed their importance for SARS-CoV-2 propagation by cataloging the effects of specific pathway inhibitors. This revealed that SARS-CoV-2 strongly inhibits mitochondrial oxidative phosphorylation (OXPHOS) resulting in increased mitochondrial reactive oxygen species (mROS) production. The elevated mROS stabilizes HIF-1α which redirects carbon molecules from mitochondrial oxidation through glycolysis and the pentose phosphate pathway (PPP) to provide substrates for viral biogenesis...
April 11, 2024: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://read.qxmd.com/read/38613283/study-of-high-transverse-momentum-higgs-boson-production-in-association-with-a-vector-boson-in-the-qqbb-final-state-with-the-atlas-detector
#24
JOURNAL ARTICLE
G Aad, B Abbott, K Abeling, N J Abicht, S H Abidi, A Aboulhorma, H Abramowicz, H Abreu, Y Abulaiti, B S Acharya, C Adam Bourdarios, L Adamczyk, S V Addepalli, M J Addison, J Adelman, A Adiguzel, T Adye, A A Affolder, Y Afik, M N Agaras, J Agarwala, A Aggarwal, C Agheorghiesei, A Ahmad, F Ahmadov, W S Ahmed, S Ahuja, X Ai, G Aielli, A Aikot, M Ait Tamlihat, B Aitbenchikh, I Aizenberg, M Akbiyik, T P A Åkesson, A V Akimov, D Akiyama, N N Akolkar, S Aktas, K Al Khoury, G L Alberghi, J Albert, P Albicocco, G L Albouy, S Alderweireldt, Z L Alegria, M Aleksa, I N Aleksandrov, C Alexa, T Alexopoulos, F Alfonsi, M Algren, M Alhroob, B Ali, H M J Ali, S Ali, S W Alibocus, M Aliev, G Alimonti, W Alkakhi, C Allaire, B M M Allbrooke, J F Allen, C A Allendes Flores, P P Allport, A Aloisio, F Alonso, C Alpigiani, M Alvarez Estevez, A Alvarez Fernandez, M Alves Cardoso, M G Alviggi, M Aly, Y Amaral Coutinho, A Ambler, C Amelung, M Amerl, C G Ames, D Amidei, S P Amor Dos Santos, K R Amos, V Ananiev, C Anastopoulos, T Andeen, J K Anders, S Y Andrean, A Andreazza, S Angelidakis, A Angerami, A V Anisenkov, A Annovi, C Antel, M T Anthony, E Antipov, M Antonelli, F Anulli, M Aoki, T Aoki, J A Aparisi Pozo, M A Aparo, L Aperio Bella, C Appelt, A Apyan, N Aranzabal, S J Arbiol Val, C Arcangeletti, A T H Arce, E Arena, J-F Arguin, S Argyropoulos, J-H Arling, O Arnaez, H Arnold, G Artoni, H Asada, K Asai, S Asai, N A Asbah, K Assamagan, R Astalos, S Atashi, R J Atkin, M Atkinson, H Atmani, P A Atmasiddha, K Augsten, S Auricchio, A D Auriol, V A Austrup, G Avolio, K Axiotis, G Azuelos, D Babal, H Bachacou, K Bachas, A Bachiu, F Backman, A Badea, T M Baer, P Bagnaia, M Bahmani, D Bahner, A J Bailey, V R Bailey, J T Baines, L Baines, O K Baker, E Bakos, D Bakshi Gupta, V Balakrishnan, R Balasubramanian, E M Baldin, P Balek, E Ballabene, F Balli, L M Baltes, W K Balunas, J Balz, E Banas, M Bandieramonte, A Bandyopadhyay, S Bansal, L Barak, M Barakat, E L Barberio, D Barberis, M Barbero, M Z Barel, K N Barends, T Barillari, M-S Barisits, T Barklow, P Baron, D A Baron Moreno, A Baroncelli, G Barone, A J Barr, J D Barr, L Barranco Navarro, F Barreiro, J Barreiro Guimarães da Costa, U Barron, M G Barros Teixeira, S Barsov, F Bartels, R Bartoldus, A E Barton, P Bartos, A Basan, M Baselga, A Bassalat, M J Basso, C R Basson, R L Bates, S Batlamous, J R Batley, B Batool, M Battaglia, D Battulga, M Bauce, M Bauer, P Bauer, L T Bazzano Hurrell, J B Beacham, T Beau, J Y Beaucamp, P H Beauchemin, P Bechtle, H P Beck, K Becker, A J Beddall, V A Bednyakov, C P Bee, L J Beemster, T A Beermann, M Begalli, M Begel, A Behera, J K Behr, J F Beirer, F Beisiegel, M Belfkir, G Bella, L Bellagamba, A Bellerive, P Bellos, K Beloborodov, D Benchekroun, F Bendebba, Y Benhammou, M Benoit, S Bentvelsen, L Beresford, M Beretta, E Bergeaas Kuutmann, N Berger, B Bergmann, J Beringer, G Bernardi, C Bernius, F U Bernlochner, F Bernon, A Berrocal Guardia, T Berry, P Berta, A Berthold, I A Bertram, S Bethke, A Betti, A J Bevan, N K Bhalla, M Bhamjee, S Bhatta, D S Bhattacharya, P Bhattarai, V S Bhopatkar, R Bi, R M Bianchi, G Bianco, O Biebel, R Bielski, M Biglietti, M Bindi, A Bingul, C Bini, A Biondini, C J Birch-Sykes, G A Bird, M Birman, M Biros, S Biryukov, T Bisanz, E Bisceglie, J P Biswal, D Biswas, A Bitadze, K Bjørke, I Bloch, A Blue, U Blumenschein, J Blumenthal, G J Bobbink, V S Bobrovnikov, M Boehler, B Boehm, D Bogavac, A G Bogdanchikov, C Bohm, V Boisvert, P Bokan, T Bold, M Bomben, M Bona, M Boonekamp, C D Booth, A G Borbély, I S Bordulev, H M Borecka-Bielska, G Borissov, D Bortoletto, D Boscherini, M Bosman, J D Bossio Sola, K Bouaouda, N Bouchhar, J Boudreau, E V Bouhova-Thacker, D Boumediene, R Bouquet, A Boveia, J Boyd, D Boye, I R Boyko, J Bracinik, N Brahimi, G Brandt, O Brandt, F Braren, B Brau, J E Brau, R Brener, L Brenner, R Brenner, S Bressler, D Britton, D Britzger, I Brock, G Brooijmans, W K Brooks, E Brost, L M Brown, L E Bruce, T L Bruckler, P A Bruckman de Renstrom, B Brüers, A Bruni, G Bruni, M Bruschi, N Bruscino, T Buanes, Q Buat, D Buchin, A G Buckley, O Bulekov, B A Bullard, S Burdin, C D Burgard, A M Burger, B Burghgrave, O Burlayenko, J T P Burr, C D Burton, J C Burzynski, E L Busch, V Büscher, P J Bussey, J M Butler, C M Buttar, J M Butterworth, W Buttinger, C J Buxo Vazquez, A R Buzykaev, S Cabrera Urbán, L Cadamuro, D Caforio, H Cai, Y Cai, Y Cai, V M M Cairo, O Cakir, N Calace, P Calafiura, G Calderini, P Calfayan, G Callea, L P Caloba, D Calvet, S Calvet, M Calvetti, R Camacho Toro, S Camarda, D Camarero Munoz, P Camarri, M T Camerlingo, D Cameron, C Camincher, M Campanelli, A Camplani, V Canale, A Canesse, J Cantero, Y Cao, F Capocasa, M Capua, A Carbone, R Cardarelli, J C J Cardenas, F Cardillo, G Carducci, T Carli, G Carlino, J I Carlotto, B T Carlson, E M Carlson, L Carminati, A Carnelli, M Carnesale, S Caron, E Carquin, S Carrá, G Carratta, F Carrio Argos, J W S Carter, T M Carter, M P Casado, M Caspar, F L Castillo, L Castillo Garcia, V Castillo Gimenez, N F Castro, A Catinaccio, J R Catmore, V Cavaliere, N Cavalli, V Cavasinni, Y C Cekmecelioglu, E Celebi, F Celli, M S Centonze, V Cepaitis, K Cerny, A S Cerqueira, A Cerri, L Cerrito, F Cerutti, B Cervato, A Cervelli, G Cesarini, S A Cetin, D Chakraborty, J Chan, W Y Chan, J D Chapman, E Chapon, B Chargeishvili, D G Charlton, M Chatterjee, C Chauhan, S Chekanov, S V Chekulaev, G A Chelkov, A Chen, B Chen, B Chen, H Chen, H Chen, J Chen, J Chen, M Chen, S Chen, S J Chen, X Chen, X Chen, Y Chen, C L Cheng, H C Cheng, S Cheong, A Cheplakov, E Cheremushkina, E Cherepanova, R Cherkaoui El Moursli, E Cheu, K Cheung, L Chevalier, V Chiarella, G Chiarelli, N Chiedde, G Chiodini, A S Chisholm, A Chitan, M Chitishvili, M V Chizhov, K Choi, A R Chomont, Y Chou, E Y S Chow, T Chowdhury, K L Chu, M C Chu, X Chu, J Chudoba, J J Chwastowski, D Cieri, K M Ciesla, V Cindro, A Ciocio, F Cirotto, Z H Citron, M Citterio, D A Ciubotaru, A Clark, P J Clark, C Clarry, J M Clavijo Columbie, S E Clawson, C Clement, J Clercx, Y Coadou, M Cobal, A Coccaro, R F Coelho Barrue, R Coelho Lopes De Sa, S Coelli, A E C Coimbra, B Cole, J Collot, P Conde Muiño, M P Connell, S H Connell, I A Connelly, E I Conroy, F Conventi, H G Cooke, A M Cooper-Sarkar, A Cordeiro Oudot Choi, L D Corpe, M Corradi, F Corriveau, A Cortes-Gonzalez, M J Costa, F Costanza, D Costanzo, B M Cote, G Cowan, K Cranmer, D Cremonini, S Crépé-Renaudin, F Crescioli, M Cristinziani, M Cristoforetti, V Croft, J E Crosby, G Crosetti, A Cueto, T Cuhadar Donszelmann, H Cui, Z Cui, W R Cunningham, F Curcio, P Czodrowski, M M Czurylo, M J Da Cunha Sargedas De Sousa, J V Da Fonseca Pinto, C Da Via, W Dabrowski, T Dado, S Dahbi, T Dai, D Dal Santo, C Dallapiccola, M Dam, G D'amen, V D'Amico, J Damp, J R Dandoy, M Danninger, V Dao, G Darbo, S Darmora, S J Das, S D'Auria, C David, T Davidek, B Davis-Purcell, I Dawson, H A Day-Hall, K De, R De Asmundis, N De Biase, S De Castro, N De Groot, P de Jong, H De la Torre, A De Maria, A De Salvo, U De Sanctis, F De Santis, A De Santo, J B De Vivie De Regie, D V Dedovich, J Degens, A M Deiana, F Del Corso, J Del Peso, F Del Rio, L Delagrange, F Deliot, C M Delitzsch, M Della Pietra, D Della Volpe, A Dell'Acqua, L Dell'Asta, M Delmastro, P A Delsart, S Demers, M Demichev, S P Denisov, L D'Eramo, D Derendarz, F Derue, P Dervan, K Desch, C Deutsch, F A Di Bello, A Di Ciaccio, L Di Ciaccio, A Di Domenico, C Di Donato, A Di Girolamo, G Di Gregorio, A Di Luca, B Di Micco, R Di Nardo, C Diaconu, M Diamantopoulou, F A Dias, T Dias Do Vale, M A Diaz, F G Diaz Capriles, M Didenko, E B Diehl, L Diehl, S Díez Cornell, C Diez Pardos, C Dimitriadi, A Dimitrievska, J Dingfelder, I-M Dinu, S J Dittmeier, F Dittus, F Djama, T Djobava, C Doglioni, A Dohnalova, J Dolejsi, Z Dolezal, K M Dona, M Donadelli, B Dong, J Donini, A D'Onofrio, M D'Onofrio, J Dopke, A Doria, N Dos Santos Fernandes, P Dougan, M T Dova, A T Doyle, M A Draguet, E Dreyer, I Drivas-Koulouris, M Drnevich, A S Drobac, M Drozdova, D Du, T A du Pree, F Dubinin, M Dubovsky, E Duchovni, G Duckeck, O A Ducu, D Duda, A Dudarev, E R Duden, M D'uffizi, L Duflot, M Dührssen, A E Dumitriu, M Dunford, S Dungs, K Dunne, A Duperrin, H Duran Yildiz, M Düren, A Durglishvili, B L Dwyer, G I Dyckes, M Dyndal, B S Dziedzic, Z O Earnshaw, G H Eberwein, B Eckerova, S Eggebrecht, E Egidio Purcino De Souza, L F Ehrke, G Eigen, K Einsweiler, T Ekelof, P A Ekman, S El Farkh, Y El Ghazali, H El Jarrari, A El Moussaouy, V Ellajosyula, M Ellert, F Ellinghaus, N Ellis, J Elmsheuser, M Elsing, D Emeliyanov, Y Enari, I Ene, S Epari, P A Erland, M Errenst, M Escalier, C Escobar, E Etzion, G Evans, H Evans, L S Evans, M O Evans, A Ezhilov, S Ezzarqtouni, F Fabbri, L Fabbri, G Facini, V Fadeyev, R M Fakhrutdinov, D Fakoudis, S Falciano, L F Falda Ulhoa Coelho, P J Falke, J Faltova, C Fan, Y Fan, Y Fang, M Fanti, M Faraj, Z Farazpay, A Farbin, A Farilla, T Farooque, S M Farrington, F Fassi, D Fassouliotis, M Faucci Giannelli, W J Fawcett, L Fayard, P Federic, P Federicova, O L Fedin, G Fedotov, M Feickert, L Feligioni, D E Fellers, C Feng, M Feng, Z Feng, M J Fenton, A B Fenyuk, L Ferencz, R A M Ferguson, S I Fernandez Luengo, P Fernandez Martinez, M J V Fernoux, J Ferrando, A Ferrari, P Ferrari, R Ferrari, D Ferrere, C Ferretti, F Fiedler, P Fiedler, A Filipčič, E K Filmer, F Filthaut, M C N Fiolhais, L Fiorini, W C Fisher, T Fitschen, P M Fitzhugh, I Fleck, P Fleischmann, T Flick, M Flores, L R Flores Castillo, L Flores Sanz De Acedo, F M Follega, N Fomin, J H Foo, A Formica, A C Forti, E Fortin, A W Fortman, M G Foti, L Fountas, D Fournier, H Fox, P Francavilla, S Francescato, S Franchellucci, M Franchini, S Franchino, D Francis, L Franco, V Franco Lima, L Franconi, M Franklin, G Frattari, A C Freegard, W S Freund, Y Y Frid, J Friend, N Fritzsche, A Froch, D Froidevaux, J A Frost, Y Fu, S Fuenzalida Garrido, M Fujimoto, K Y Fung, E Furtado De Simas Filho, M Furukawa, J Fuster, A Gabrielli, A Gabrielli, P Gadow, G Gagliardi, L G Gagnon, E J Gallas, B J Gallop, K K Gan, S Ganguly, Y Gao, F M Garay Walls, B Garcia, C García, A Garcia Alonso, A G Garcia Caffaro, J E García Navarro, M Garcia-Sciveres, G L Gardner, R W Gardner, N Garelli, D Garg, R B Garg, J M Gargan, C A Garner, C M Garvey, P Gaspar, V K Gassmann, G Gaudio, V Gautam, P Gauzzi, I L Gavrilenko, A Gavrilyuk, C Gay, G Gaycken, E N Gazis, A A Geanta, C M Gee, A Gekow, C Gemme, M H Genest, S Gentile, A D Gentry, S George, W F George, T Geralis, P Gessinger-Befurt, M E Geyik, M Ghani, M Ghneimat, K Ghorbanian, A Ghosal, A Ghosh, A Ghosh, B Giacobbe, S Giagu, T Giani, P Giannetti, A Giannini, S M Gibson, M Gignac, D T Gil, A K Gilbert, B J Gilbert, D Gillberg, G Gilles, N E K Gillwald, L Ginabat, D M Gingrich, M P Giordani, P F Giraud, G Giugliarelli, D Giugni, F Giuli, I Gkialas, L K Gladilin, C Glasman, G R Gledhill, G Glemža, M Glisic, I Gnesi, Y Go, M Goblirsch-Kolb, B Gocke, D Godin, B Gokturk, S Goldfarb, T Golling, M G D Gololo, D Golubkov, J P Gombas, A Gomes, G Gomes Da Silva, A J Gomez Delegido, R Gonçalo, G Gonella, L Gonella, A Gongadze, F Gonnella, J L Gonski, R Y González Andana, S González de la Hoz, R Gonzalez Lopez, C Gonzalez Renteria, M V Gonzalez Rodrigues, R Gonzalez Suarez, S Gonzalez-Sevilla, G R Gonzalvo Rodriguez, L Goossens, B Gorini, E Gorini, A Gorišek, T C Gosart, A T Goshaw, M I Gostkin, S Goswami, C A Gottardo, S A Gotz, M Gouighri, V Goumarre, A G Goussiou, N Govender, I Grabowska-Bold, K Graham, E Gramstad, S Grancagnolo, M Grandi, C M Grant, P M Gravila, F G Gravili, H M Gray, M Greco, C Grefe, I M Gregor, P Grenier, S G Grewe, C Grieco, A A Grillo, K Grimm, S Grinstein, J-F Grivaz, E Gross, J Grosse-Knetter, C Grud, J C Grundy, L Guan, W Guan, C Gubbels, J G R Guerrero Rojas, G Guerrieri, F Guescini, R Gugel, J A M Guhit, A Guida, E Guilloton, S Guindon, F Guo, J Guo, L Guo, Y Guo, R Gupta, R Gupta, S Gurbuz, S S Gurdasani, G Gustavino, M Guth, P Gutierrez, L F Gutierrez Zagazeta, M Gutsche, C Gutschow, C Gwenlan, C B Gwilliam, E S Haaland, A Haas, M Habedank, C Haber, H K Hadavand, A Hadef, S Hadzic, A I Hagan, J J Hahn, E H Haines, M Haleem, J Haley, J J Hall, G D Hallewell, L Halser, K Hamano, M Hamer, G N Hamity, E J Hampshire, J Han, K Han, L Han, L Han, S Han, Y F Han, K Hanagaki, M Hance, D A Hangal, H Hanif, M D Hank, J B Hansen, P H Hansen, K Hara, D Harada, T Harenberg, S Harkusha, M L Harris, Y T Harris, J Harrison, N M Harrison, P F Harrison, N M Hartman, N M Hartmann, Y Hasegawa, R Hauser, C M Hawkes, R J Hawkings, Y Hayashi, S Hayashida, D Hayden, C Hayes, R L Hayes, C P Hays, J M Hays, H S Hayward, F He, M He, Y He, Y He, N B Heatley, V Hedberg, A L Heggelund, N D Hehir, C Heidegger, K K Heidegger, W D Heidorn, J Heilman, S Heim, T Heim, J G Heinlein, J J Heinrich, L Heinrich, J Hejbal, L Helary, A Held, S Hellesund, C M Helling, S Hellman, R C W Henderson, L Henkelmann, A M Henriques Correia, H Herde, Y Hernández Jiménez, L M Herrmann, T Herrmann, G Herten, R Hertenberger, L Hervas, M E Hesping, N P Hessey, H Hibi, E Hill, S J Hillier, J R Hinds, F Hinterkeuser, M Hirose, S Hirose, D Hirschbuehl, T G Hitchings, B Hiti, J Hobbs, R Hobincu, N Hod, M C Hodgkinson, B H Hodkinson, A Hoecker, D D Hofer, J Hofer, T Holm, M Holzbock, L B A H Hommels, B P Honan, J Hong, T M Hong, B H Hooberman, W H Hopkins, Y Horii, S Hou, A S Howard, J Howarth, J Hoya, M Hrabovsky, A Hrynevich, T Hryn'ova, P J Hsu, S-C Hsu, Q Hu, Y F Hu, S Huang, X Huang, X Huang, Y Huang, Y Huang, Z Huang, Z Hubacek, M Huebner, F Huegging, T B Huffman, C A Hugli, M Huhtinen, S K Huiberts, R Hulsken, N Huseynov, J Huston, J Huth, R Hyneman, G Iacobucci, G Iakovidis, I Ibragimov, L Iconomidou-Fayard, J P Iddon, P Iengo, R Iguchi, T Iizawa, Y Ikegami, N Ilic, H Imam, M Ince Lezki, T Ingebretsen Carlson, G Introzzi, M Iodice, V Ippolito, R K Irwin, M Ishino, W Islam, C Issever, S Istin, H Ito, J M Iturbe Ponce, R Iuppa, A Ivina, J M Izen, V Izzo, P Jacka, P Jackson, R M Jacobs, B P Jaeger, C S Jagfeld, G Jain, P Jain, K Jakobs, T Jakoubek, J Jamieson, K W Janas, M Javurkova, F Jeanneau, L Jeanty, J Jejelava, P Jenni, C E Jessiman, S Jézéquel, C Jia, J Jia, X Jia, X Jia, Z Jia, S Jiggins, J Jimenez Pena, S Jin, A Jinaru, O Jinnouchi, P Johansson, K A Johns, J W Johnson, D M Jones, E Jones, P Jones, R W L Jones, T J Jones, H L Joos, R Joshi, J Jovicevic, X Ju, J J Junggeburth, T Junkermann, A Juste Rozas, M K Juzek, S Kabana, A Kaczmarska, M Kado, H Kagan, M Kagan, A Kahn, A Kahn, C Kahra, T Kaji, E Kajomovitz, N Kakati, I Kalaitzidou, C W Kalderon, A Kamenshchikov, N J Kang, D Kar, K Karava, M J Kareem, E Karentzos, I Karkanias, O Karkout, S N Karpov, Z M Karpova, V Kartvelishvili, A N Karyukhin, E Kasimi, J Katzy, S Kaur, K Kawade, M P Kawale, C Kawamoto, T Kawamoto, E F Kay, F I Kaya, S Kazakos, V F Kazanin, Y Ke, J M Keaveney, R Keeler, G V Kehris, J S Keller, A S Kelly, J J Kempster, K E Kennedy, P D Kennedy, O Kepka, B P Kerridge, S Kersten, B P Kerševan, S Keshri, L Keszeghova, S Ketabchi Haghighat, R A Khan, A Khanov, A G Kharlamov, T Kharlamova, E E Khoda, M Kholodenko, T J Khoo, G Khoriauli, J Khubua, Y A R Khwaira, A Kilgallon, D W Kim, Y K Kim, N Kimura, M K Kingston, A Kirchhoff, C Kirfel, F Kirfel, J Kirk, A E Kiryunin, C Kitsaki, O Kivernyk, M Klassen, C Klein, L Klein, M H Klein, M Klein, S B Klein, U Klein, P Klimek, A Klimentov, T Klioutchnikova, P Kluit, S Kluth, E Kneringer, T M Knight, A Knue, R Kobayashi, D Kobylianskii, S F Koch, M Kocian, P Kodyš, D M Koeck, P T Koenig, T Koffas, O Kolay, I Koletsou, T Komarek, K Köneke, A X Y Kong, T Kono, N Konstantinidis, P Kontaxakis, B Konya, R Kopeliansky, S Koperny, K Korcyl, K Kordas, A Korn, S Korn, I Korolkov, N Korotkova, B Kortman, O Kortner, S Kortner, W H Kostecka, V V Kostyukhin, A Kotsokechagia, A Kotwal, A Koulouris, A Kourkoumeli-Charalampidi, C Kourkoumelis, E Kourlitis, O Kovanda, R Kowalewski, W Kozanecki, A S Kozhin, V A Kramarenko, G Kramberger, P Kramer, M W Krasny, A Krasznahorkay, J W Kraus, J A Kremer, T Kresse, J Kretzschmar, K Kreul, P Krieger, S Krishnamurthy, M Krivos, K Krizka, K Kroeninger, H Kroha, J Kroll, J Kroll, K S Krowpman, U Kruchonak, H Krüger, N Krumnack, M C Kruse, O Kuchinskaia, S Kuday, S Kuehn, R Kuesters, T Kuhl, V Kukhtin, Y Kulchitsky, S Kuleshov, M Kumar, N Kumari, P Kumari, A Kupco, T Kupfer, A Kupich, O Kuprash, H Kurashige, L L Kurchaninov, O Kurdysh, Y A Kurochkin, A Kurova, M Kuze, A K Kvam, J Kvita, T Kwan, N G Kyriacou, L A O Laatu, C Lacasta, F Lacava, H Lacker, D Lacour, N N Lad, E Ladygin, B Laforge, T Lagouri, F Z Lahbabi, S Lai, I K Lakomiec, N Lalloue, J E Lambert, S Lammers, W Lampl, C Lampoudis, A N Lancaster, E Lançon, U Landgraf, M P J Landon, V S Lang, R J Langenberg, O K B Langrekken, A J Lankford, F Lanni, K Lantzsch, A Lanza, A Lapertosa, J F Laporte, T Lari, F Lasagni Manghi, M Lassnig, V Latonova, A Laudrain, A Laurier, S D Lawlor, Z 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Virdee, A Vishwakarma, A Visibile, C Vittori, I Vivarelli, E Voevodina, F Vogel, J C Voigt, P Vokac, Yu Volkotrub, J Von Ahnen, E Von Toerne, B Vormwald, V Vorobel, K Vorobev, M Vos, K Voss, J H Vossebeld, M Vozak, L Vozdecky, N Vranjes, M Vranjes Milosavljevic, M Vreeswijk, N K Vu, R Vuillermet, O Vujinovic, I Vukotic, S Wada, C Wagner, J M Wagner, W Wagner, S Wahdan, H Wahlberg, M Wakida, J Walder, R Walker, W Walkowiak, A Wall, T Wamorkar, A Z Wang, C Wang, C Wang, H Wang, J Wang, R-J Wang, R Wang, R Wang, S M Wang, S Wang, T Wang, W T Wang, W Wang, X Wang, X Wang, X Wang, Y Wang, Y Wang, Z Wang, Z Wang, Z Wang, A Warburton, R J Ward, N Warrack, S Waterhouse, A T Watson, H Watson, M F Watson, E Watton, G Watts, B M Waugh, C Weber, H A Weber, M S Weber, S M Weber, C Wei, Y Wei, A R Weidberg, E J Weik, J Weingarten, M Weirich, C Weiser, C J Wells, T Wenaus, B Wendland, T Wengler, N S Wenke, N Wermes, M Wessels, A M Wharton, A S White, A White, M J White, D Whiteson, L Wickremasinghe, W Wiedenmann, M Wielers, C Wiglesworth, D J Wilbern, H G Wilkens, D M Williams, H H Williams, S Williams, S Willocq, B J Wilson, P J Windischhofer, F I Winkel, F Winklmeier, B T Winter, J K Winter, M Wittgen, M Wobisch, Z Wolffs, J Wollrath, M W Wolter, H Wolters, A F Wongel, E L Woodward, S D Worm, B K Wosiek, K W Woźniak, S Wozniewski, K Wraight, C Wu, J Wu, M Wu, M Wu, S L Wu, X Wu, Y Wu, Z Wu, J Wuerzinger, T R Wyatt, B M Wynne, S Xella, L Xia, M Xia, J Xiang, M Xie, X Xie, S Xin, A Xiong, J Xiong, D Xu, H Xu, L Xu, R Xu, T Xu, Y Xu, Z Xu, Z Xu, B Yabsley, S Yacoob, Y Yamaguchi, E Yamashita, H Yamauchi, T Yamazaki, Y Yamazaki, J Yan, S Yan, Z Yan, H J Yang, H T Yang, S Yang, T Yang, X Yang, X Yang, Y Yang, Y Yang, Z Yang, W-M Yao, Y C Yap, H Ye, H Ye, J Ye, S Ye, X Ye, Y Yeh, I Yeletskikh, B K Yeo, M R Yexley, P Yin, K Yorita, S Younas, C J S Young, C Young, C Yu, Y Yu, M Yuan, R Yuan, L Yue, M Zaazoua, B Zabinski, E Zaid, Z K Zak, T Zakareishvili, N Zakharchuk, S Zambito, J A Zamora Saa, J Zang, D Zanzi, O Zaplatilek, C Zeitnitz, H Zeng, J C Zeng, D T Zenger, O Zenin, T Ženiš, S Zenz, S Zerradi, D Zerwas, M Zhai, B Zhang, D F Zhang, J Zhang, J Zhang, K Zhang, L Zhang, P Zhang, R Zhang, S Zhang, S Zhang, T Zhang, X Zhang, X Zhang, Y Zhang, Y Zhang, Y Zhang, Z Zhang, Z Zhang, H Zhao, T Zhao, Y Zhao, Z Zhao, A Zhemchugov, J Zheng, K Zheng, X Zheng, Z Zheng, D Zhong, B Zhou, H Zhou, N Zhou, Y Zhou, Y Zhou, C G Zhu, J Zhu, Y Zhu, Y Zhu, X Zhuang, K Zhukov, V Zhulanov, N I Zimine, J Zinsser, M Ziolkowski, L Živković, A Zoccoli, K Zoch, T G Zorbas, O Zormpa, W Zou, L Zwalinski
This Letter presents the first study of Higgs boson production in association with a vector boson (V=W or Z) in the fully hadronic qqbb final state using data recorded by the ATLAS detector at the LHC in proton-proton collisions at sqrt[s]=13  TeV and corresponding to an integrated luminosity of 137  fb^{-1}. The vector bosons and Higgs bosons are each reconstructed as large-radius jets and tagged using jet substructure techniques. Dedicated tagging algorithms exploiting b-tagging properties are used to identify jets consistent with Higgs bosons decaying into bb[over ¯]...
March 29, 2024: Physical Review Letters
https://read.qxmd.com/read/38612511/-cu-nn-1-2-clo-4-a-copper-i-complex-as-an-antimicrobial-agent-for-the-treatment-of-piscirickettsiosis-in-atlantic-salmon
#25
JOURNAL ARTICLE
Mick Parra, Maialen Aldabaldetrecu, Pablo Arce, Sarita Soto-Aguilera, Rodrigo Vargas, Juan Guerrero, Mario Tello, Brenda Modak
Piscirickettsia salmonis is the pathogen that most affects the salmon industry in Chile. Large quantities of antibiotics have been used to control it. In search of alternatives, we have developed [Cu(NN1 )2 ]ClO4 where NN1 = 6-((quinolin-2-ylmethylene)amino)-2H-chromen-2-one. The antibacterial capacity of [Cu(NN1 )2 ]ClO4 was determined. Subsequently, the effect of the administration of [Cu(NN1 )2 ]ClO4 on the growth of S. salar , modulation of the immune system and the intestinal microbiota was studied. Finally, the ability to protect against a challenge with P...
March 26, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38612423/co-culture-of-p-gingivalis-and-f-nucleatum-synergistically-elevates-il-6-expression-via-tlr4-signaling-in-oral-keratinocytes
#26
JOURNAL ARTICLE
Lucas Yáñez, Cristopher Soto, Héctor Tapia, Martín Pacheco, Javiera Tapia, Gabriela Osses, Daniela Salinas, Victoria Rojas-Celis, Anilei Hoare, Andrew F G Quest, Jessica Díaz-Elizondo, José Manuel Pérez-Donoso, Denisse Bravo
Periodontitis, characterized by persistent inflammation in the periodontium, is intricately connected to systemic diseases, including oral cancer. Bacteria, such as Porphyromonas gingivalis and Fusobacterium nucleatum , play a pivotal role in periodontitis development because they contribute to dysbiosis and tissue destruction. Thus, comprehending the interplay between these bacteria and their impacts on inflammation holds significant relevance in clinical understanding and treatment advancement. In the present work, we explored, for the first time, their impacts on the expressions of pro-inflammatory mediators after infecting oral keratinocytes (OKs) with a co-culture of pre-incubated P...
March 23, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38612342/feline-facial-spindle-cell-tumors-in-29-cats-histomorphological-and-immunohistochemical-characterization
#27
JOURNAL ARTICLE
Sara Soto, Sohvi Blatter, Stefan Hobi, Marco Steck, Julia Lechmann, Silvia Rüfenacht, Nicolas Kühn, Maja Ruetten, Nataliia Ignatenko, Christiane Krudewig
Soft tissue tumors/sarcomas (STSs) in felines, encompassing a variety of mesenchymal tumors with similar histomorphological features, present diagnostic challenges due to their diverse cellular origins and the overlap with other tumor types such as feline sarcoid. This study aimed to delineate the clinical, histomorphological, and immunohistochemical characteristics of 34 feline facial spindle cell tumors affecting 29 cats, including testing for bovine papillomavirus type 14 (BPV14), the virus causing feline sarcoids...
April 4, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38611719/the-cancer-protective-potential-of-protocatechuic-acid-a-narrative-review
#28
REVIEW
Jorge Cadena-Iñiguez, Edelmiro Santiago-Osorio, Nancy Sánchez-Flores, Sandra Salazar-Aguilar, Ramón Marcos Soto-Hernández, María de la Luz Riviello-Flores, Víctor Manuel Macías-Zaragoza, Itzen Aguiñiga-Sánchez
Cancer is one of the leading causes of death worldwide, making the search for alternatives for its control a critical issue. In this context, exploring alternatives from natural sources, such as certain vegetables containing a variety of secondary metabolites with beneficial effects on the body and that play a crucial role in the fight against cancer, is essential. Among the compounds with the greatest efficacy in controlling this disease, those with antioxidant activity, particularly phenolic com-pounds, stand out...
March 23, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38611509/long-lasting-silver-nanoparticles-synthesized-with-tagetes-erecta-and-their-antibacterial-activity-against-erwinia-amylovora-a-serious-rosaceous-pathogen
#29
JOURNAL ARTICLE
Johana Zarate-Escobedo, Hilda Araceli Zavaleta-Mancera, Ramón Marcos Soto-Hernández, Paulino Pérez-Rodríguez, Alfredo Rafael Vilchis-Nestor, Hilda Victoria Silva-Rojas, Libia Iris Trejo-Téllez
A rapid, eco-friendly, and simple method for the synthesis of long-lasting (2 years) silver nanoparticles (AgNPs) is reported using aqueous leaf and petal extracts of Tagetes erecta L. The particles were characterized using UV-Visible spectrophotometry and the analytical and crystallographic techniques of transmission electron microscopy (TEM). The longevity of the AgNPs was studied using UV-Vis and high-resolution TEM. The antibacterial activity of the particles against Erwinia amylovora was evaluated using the Kirby-Bauer disk diffusion method...
March 29, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38611342/exploring-the-nutritional-and-bioactive-potential-of-olive-leaf-residues-a-focus-on-minerals-and-polyphenols-in-the-context-of-spain-s-olive-oil-production
#30
JOURNAL ARTICLE
Carolina L Ronca, Carmen Duque-Soto, Cristina Samaniego-Sánchez, María Encarnación Morales-Hernández, Manuel Olalla-Herrera, Jesús Lozano-Sánchez, Rafael Giménez Martínez
Lyophilized plant-origin extracts are rich in highly potent antioxidant polyphenols. In order to incorporate them into food products, it is necessary to protect these phytochemicals from atmospheric factors such as heat, light, moisture, or pH, and to enhance their bioavailability due to their low solubility. To address these challenges, recent studies have focused on the development of encapsulation techniques for antioxidant compounds within polymeric structures. In this study, lyophilized olive leaf extracts were microencapsulated with the aim of overcoming the aforementioned challenges...
March 28, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38609206/corrigendum-to-physiologic-adaptation-to-macronutrient-change-distorts-findings-from-short-dietary-trials-reanalysis-of-a-metabolic-ward-study-j-nutr-154-2024-1080-1086
#31
Adrian Soto-Mota, Lisa T Jansen, Nicholas G Norwitz, Mark A Pereira, Cara B Ebbeling, David S Ludwig
No abstract text is available yet for this article.
April 2024: Journal of Nutrition
https://read.qxmd.com/read/38606759/how-conspecific-and-allospecific-eggs-and-larvae-drive-oviposition-preference-in-drosophila
#32
JOURNAL ARTICLE
Rolando D Moreira-Soto, Mohammed A Khallaf, Bill S Hansson, Markus Knaden
Where to lay the eggs is a crucial decision for females as it influences the success of their offspring. Female flies prefer to lay eggs on food already occupied and consumed by larvae, which facilitates social feeding, but potentially could also lead to detrimental interactions between species. Whether females can modulate their attraction to cues associated with different species is unknown. Here we analyzed the chemical profiles of eggs and larvae of 16 Drosophila species, and tested whether Drosophila flies would be attracted to larvae treated food or food with eggs from 6 different Drosophila species...
April 12, 2024: Chemical Senses
https://read.qxmd.com/read/38606444/trunk-injection-of-citrus-trees-with-a-polymeric-nanobactericide-reduces-huanglongbing-severity-caused-by-candidatus-liberibacter-asiaticus
#33
JOURNAL ARTICLE
Ramiro Guerrero-Santos, Gabriela Cabrales-Orona, John Paul Délano-Frier, Judith Cabello-Romero, José Román Torres-Lubián, José Humberto Valenzuela-Soto
Huanglongbing (HLB) is a disease caused by the phloem- limited Candidatus Liberibacter asiaticus (CLas) that affects the citrus industry worldwide. To date, only indirect strategies have been implemented to eradicate HLB. Included among these is the population control of the psyllid vector (Diaphorina citri), which usually provides inconsistent results. Even though strategies for direct CLas suppression seem a priori more promising, only a handful of reports have been focused on a confrontation of the pathogen...
April 2024: Plant Pathology Journal
https://read.qxmd.com/read/38604897/reno-study-clinical-characteristics-treatment-patterns-and-survival-results-in-patients-with-metastatic-renal-cell-carcinoma-in-northern-spain
#34
JOURNAL ARTICLE
Laura Basterretxea Badiola, Nuria Lainez Milagro, Diego Cacho Lavín, Sandra López Peraita, Mikel Arruti Ibarbia, Mireia Martínez Kareaga, Teresa de Portugal Fernández Del Rivero, Diego Soto de Prado Otero, Valentín Alija López, Carlos Álvarez Fernández, Alejandra Lacalle Emborujo, Irene Gil Arnaiz, Ricardo Fernández Rodríguez, Naiara Sagastibeltza, Ignacio Duran
BACKGROUND: The current available evidence on the management of metastatic renal cell cancer (mRCC) in real life is scarce in our environment. We present a summary of the existing real-world data and the results of an analysis describing the clinical characteristics, treatments, and health outcomes of patients with mRCC in northern Spain. METHODS: Retrospective observational study. Adult patients diagnosed with mRCC between Jan 2007 and Dec 2019 were included. Epidemiological, efficacy and toxicity data were collected...
March 4, 2024: Seminars in Oncology
https://read.qxmd.com/read/38602304/increasing-cadence-with-a-metronome-and-running-barefoot-changes-the-sagittal-kinematics-of-the-lower-limbs-and-trunk
#35
JOURNAL ARTICLE
Alejandro Molina-Molina, Gabriel Delgado-García, Jim Richards, Elia Mercado-Palomino, Víctor Manuel Soto-Hermoso, Pedro Ángel Latorre-Román
The purpose was to compare two non-laboratory based running retraining programs on lower limb and trunk kinematics in recreational runners. Seventy recreational runners (30 ± 7.3 years old, 40% female) were randomised to a barefoot running group (BAR), a group wearing a digital metronome with their basal cadence increased by 10% (CAD), and a control group (CON). BAR and CAD groups included intervals from 15 to 40 min over 10 weeks and 3 days/week. 3D sagittal kinematics of the ankle, knee, hip, pelvis, and trunk were measured before and after the retraining program, at comfortable and high speeds...
April 11, 2024: Journal of Sports Sciences
https://read.qxmd.com/read/38601536/pm-2-5-component-cause-of-severe-metabolically-abnormal-obesity-an-in-silico-observational-and-analytical-study
#36
JOURNAL ARTICLE
Sagrario Lobato, A Lourdes Castillo-Granada, Marcos Bucio-Pacheco, Víctor Manuel Salomón-Soto, Ramiro Álvarez-Valenzuela, Perla Margarita Meza-Inostroza, Raúl Villegas-Vizcaíno
Obesity is currently one of the most alarming pathological conditions due to the progressive increase in its prevalence. In the last decade, it has been associated with fine particulate matter suspended in the air (PM2.5 ). The purpose of this study was to explore the mechanistic interaction of PM2.5 with a high-fat diet (HFD) through the differential regulation of transcriptional signatures, aiming to identify the association of these particles with metabolically abnormal obesity. The research design was observational, using bioinformatic methods and an explanatory approach based on Rothman's causal model...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38601152/the-effects-of-pediococcus-acidilactici-ma18-5m-on-growth-performance-gut-integrity-and-immune-response-using-in-vitro-and-in-vivo-pacific-salmonid-models
#37
JOURNAL ARTICLE
Manuel Soto-Dávila, Luana Langlois Fiorotto, John W Heath, John S Lumsden, Gregor Reid, Brian Dixon
Microbial management is central to aquaculture's efficiency. Pediococcus acidilactici MA18/5M has shown promising results promoting growth, modulation of the immune response, and disease resistance in many fishes. However, the mechanisms through which this strain confers health benefits in fish are poorly understood, particularly in Pacific salmonid models. Briefly, the aims of this study were to i) assess the protective effects of P. acidilactici MA18/5M by examining gut barrier function and the expression of tight junction (TJ) and immune genes in vitro and in vivo , and ii) to determine the protective effects of this strain against a common saltwater pathogen, Vibrio anguillarum J382...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38599564/incorporating-cardiovascular-risk-assessment-into-adolescent-reproductive-health-and-primary-care-visits
#38
JOURNAL ARTICLE
Brianna Karim, Andrew Jergel, Shasha Bai, Kolbi Bradley, Santiago J Arconada Alvarez, Amanda K Gilmore, Morgan Greenleaf, Melissa J Kottke, Maren Parsell, Sierra Patterson, Mercedes Sotos-Prieto, Elizabeth Zeichner, Holly C Gooding
STUDY OBJECTIVE: This study aimed to evaluate the usability and feasibility of incorporating a cardiovascular risk assessment tool into adolescent reproductive health and primary care visits. METHODS: We recruited 60 young women ages 13-21 years to complete the HerHeart web-tool in two adolescent clinics in Atlanta, GA. Participants rated the tool's usability via the Website Analysis and Measurement Inventory (WAMMI, range 0-95) and their perceived 10-year and lifetime risk of cardiovascular disease (CVD) on a visual analog scale (range 0-10)...
April 8, 2024: Journal of Pediatric and Adolescent Gynecology
https://read.qxmd.com/read/38599083/economic-costs-of-non-native-species-in-t%C3%A3-rkiye-a-first-national-synthesis
#39
JOURNAL ARTICLE
Ali Serhan Tarkan, Esra Bayçelebi, Daniela Giannetto, Emine Demir Özden, Ayşe Yazlık, Özgür Emiroğlu, Sadi Aksu, Ahmet Uludağ, Necmi Aksoy, Hazel Baytaşoğlu, Cüneyt Kaya, Tanju Mutlu, Şerife Gülsün Kırankaya, Deniz Ergüden, Esra Per, İlhan Üremiş, Onur Candan, Aysel Kekillioğlu, Baran Yoğurtçuoğlu, F Güler Ekmekçi, Esra Başak, Hatice Özkan, Irmak Kurtul, Deniz Innal, Nurçin Killi, Sercan Yapıcı, Dinçer Ayaz, Kerim Çiçek, Oğuzcan Mol, Emre Çınar, Vedat Yeğen, Elena Angulo, Ross N Cuthbert, Ismael Soto, Franck Courchamp, Phillip J Haubrock
Biological invasions are increasingly recognised as a major global change that erodes ecosystems, societal well-being, and economies. However, comprehensive analyses of their economic ramifications are missing for most national economies, despite rapidly escalating costs globally. Türkiye is highly vulnerable to biological invasions owing to its extensive transport network and trade connections as well as its unique transcontinental position at the interface of Europe and Asia. This study presents the first analysis of the reported economic costs caused by biological invasions in Türkiye...
April 9, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38597602/redefining-piscine-lactococcosis
#40
JOURNAL ARTICLE
Taylor I Heckman, Zeinab Yazdi, Caitlin E Older, Matt J Griffin, Geoffrey C Waldbieser, Alexander M Chow, Isabella Medina Silva, Kelsey M Anenson, Julio C García, Benjamin R LaFrentz, Durda Slavic, Kathy L Toohey-Kurth, Paula Yant, Heather M Fritz, Eileen E Henderson, Rebeccah McDowall, Hugh Cai, Mark Adkison, Esteban Soto
UNLABELLED: Piscine lactococcosis is a significant threat to cultured and wild fish populations worldwide. The disease typically presents as a per-acute to acute hemorrhagic septicemia causing high morbidity and mortality, recalcitrant to antimicrobial treatment or management interventions. Historically, the disease was attributed to the gram-positive pathogen Lactococcus garvieae . However, recent work has revealed three distinct lactococcosis-causing bacteria (LCB)- L. garvieae, L. petauri, and L...
April 10, 2024: Applied and Environmental Microbiology
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