keyword
https://read.qxmd.com/read/38541875/the-effect-of-hydrostatic-pressure-on-coronary-flow-and-pressure-based-indices-of-coronary-stenosis-severity
#1
JOURNAL ARTICLE
Firas Al-Janabi, Grigoris V Karamasis, Christopher M Cook, Konstantinos Stathogiannis, Sarosh Khan, Samer Fawaz, Uzma Sajjad, Rohan Jagathesan, Paul R Kelly, Reto A Gamma, Kare H Tang, Gerald J Clesham, Thomas R Keeble, John R Davies
Background : To assess whether hydrostatic pressure gradients caused by coronary height differences in supine versus prone positioning during invasive physiological stenosis assessment affect resting and hyperaemic pressure-based indices or coronary flow. Methods : Twenty-three coronary stenoses were assessed in twenty-one patients with stable coronary artery disease. All patients had a stenosis of at least 50% visually defined on previous coronary angiography. Pd/Pa, iFR, FFR, and coronary flow velocity (APV) measured using a Doppler were recorded across the same stenosis, with the patient in the prone position, followed by repeat measurements in the standard supine position...
March 13, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541780/the-value-of-a-coronary-computed-tomography-angiography-plus-stress-cardiac-magnetic-resonance-imaging-strategy-for-the-evaluation-of-patients-with-chronic-coronary-syndrome
#2
JOURNAL ARTICLE
Gherardo Busi, Mattia Alexis Amico, Matteo Vannini, Giacomo Virgili, Angela Migliorini, Giulia Pontecorboli, Silvia Pradella, Manlio Acquafresca, Mario Moroni, Carlo Di Mario, Renato Valenti, Nazario Carrabba
Background: Noninvasive imaging methods, either anatomical or functional tests, serve as essential instruments for the appropriate management of patients with established or suspected coronary artery disease (CAD). We sought to evaluate the safety and efficacy of a coronary computed tomography angiography (CCTA) plus stress cardiac magnetic resonance imaging (S-CMR) strategy in patients with chronic coronary syndrome (CCS). Methods: Patients with suspected CCS showing intermediate coronary plaques (stenosis 30-70%) at CCTA underwent S-CMR...
March 8, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38537718/conventional-dendritic-cells-2-the-targeted-antigen-presenting-cell-induces-enhanced-type-1-immune-responses-in-mice-immunized-with-cvc1302-in-oil-formulation-cdc2-responsible-for-type-1-immunity-induced-by-cvc1302
#3
JOURNAL ARTICLE
Luping Du, Haiyan Lu, Xuwen Qiao, Yuanpeng Zhang, Liting Hou, Xiaoming Yu, Haiwei Cheng, Jin Chen, Qisheng Zheng, Jibo Hou, Guangzhi Tong
Multifunctional CD4+ T helper 1 (Th1) cells, producing IFN-γ, TNF-α and IL-2, define a correlate of vaccine-mediated protection against intracellular infection. In our previous study, we found that CVC1302 in oil formulation promoted the differentiation of IFN-γ+ /TNF-α+ /IL-2+ Th1 cells. In order to extend the application of CVC1302 in oil formulation, this study aimed to elucidate the mechanism of action in improving the Th1 immune response. Considering the signals required for the differentiation of CD4+ T cells to Th1 cells, we detected the distribution of innate immune cells and the model antigen OVA-FITC in lymph node (LN), as well as the quantity of cytokines produced by the innate immune cells...
March 25, 2024: Immunology Letters
https://read.qxmd.com/read/38527834/-clinical-features-and-risk-factors-for-invasive-fungal-sinusitis-after-allogeneic-hematopoietic-stem-cell-transplantation
#4
JOURNAL ARTICLE
H X Fu, J J Li, Y Y Zhang, Y Q Sun, X D Mo, T T Han, J Kong, M Lyu, W Han, H Chen, Y Y Chen, F R Wang, C H Yan, Y Chen, J Z Wang, Y Wang, L P Xu, X J Huang, X H Zhang
Objective: To analyze the clinical characteristics and outcomes of patients with invasive fungal sinusitis (invasive fungal rhinosinusitis, IFR) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and explored the risk factors for IFR after allo-HSCT. Methods: Nineteen patients with IFR after allo-HSCT at Peking University People's Hospital from January 2012 to December 2021 were selected as the study group, and 95 patients without IFR after allo-HSCT during this period were randomly selected as the control group (1:5 ratio) ...
January 14, 2024: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://read.qxmd.com/read/38526753/diagnostic-accuracy-of-murray-law-based-quantitative-flow-ratio-in-patients-with-severe-aortic-stenosis-undergoing-transcatheter-aortic-valve-replacement
#5
JOURNAL ARTICLE
Fukuishi Yuta, Hiroyuki Kawamori, Takayoshi Toba, Takashi Hiromasa, Satoru Sasaki, Tomoyo Hamana, Hiroyuki Fujii, Yuto Osumi, Seigo Iwane, Tetsuya Yamamoto, Shota Naniwa, Yuki Sakamoto, Koshi Matsuhama, Ken-Ichi Hirata, Hiromasa Otake
BACKGROUND: Murray law-based quantitative flow ratio (μQFR) is a novel computational method that enables accurate estimation of fractional flow reserve (FFR) using a single angiographic projection. However, its diagnostic value in patients with severe aortic stenosis (AS) remains unclear. METHOD: We included 25 consecutive patients who underwent transcatheter aortic valve replacement (TAVR) for severe AS with intermediate or greater (30-90%) coronary artery disease (CAD)...
March 25, 2024: Heart and Vessels
https://read.qxmd.com/read/38525100/controlling-crystal-morphology-of-anisotropic-zeolites-with-elemental-composition
#6
JOURNAL ARTICLE
Ondřej Veselý, Mariya Shamzhy, Wiesław J Roth, Russell E Morris, Jiří Čejka
The morphology of zeolite crystals strongly affects their textural, catalytic, and mechanical attributes. However, controlling zeolite crystal morphology without using modifiers or structure-directing agents remains a challenging task because of our limited understanding of the relationships between zeolite crystal shape, crystallization mechanism, and composition of the starting synthesis mixture. In this study, we aimed at developing a general method for controlling the morphology of zeolites by assessing the impact of the Si/T molar ratio of the synthesis gel on the growth rate of zeolite crystals in various crystallographic directions and on the final crystal morphology of the UTL germanosilicate with a 2D system of intersecting 14- and 12-ring pores...
March 20, 2024: Crystal Growth & Design
https://read.qxmd.com/read/38516003/fractional-flow-reserve-and-instantaneous-wave-free-ratio-in-coronary-artery-bypass-grafting-a-meta-analysis-and-practice-review
#7
REVIEW
R G Abbasciano, G R Layton, S Torre, N Abbaker, A Copperwheat, C Lucarelli, S Bhandari, S Nijjer, G Mikhail, R Casula, M Zakkar, A Viviano
OBJECTIVE: Fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are invasive methods to assess the functional significance of intermediate severity coronary lesions. Both indexes have been extensively validated in clinical trials in guiding revascularisation in patients with stable ischaemic heart disease undergoing percutaneous coronary intervention (PCI) with improved clinical outcomes. However, the role of these tools in coronary artery bypass grafting (CABG) is less clear...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38510505/clinical-effects-of-physiologic-lesion-testing-in-influencing-treatment-strategy-for-multi-vessel-coronary-artery-disease
#8
JOURNAL ARTICLE
Harsh Rawal, Tung D Nguyen, Efehi Igbinomwanhia, Lloyd W Klein
BACKGROUND: The application of fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) in multivessel coronary artery disease (CAD) patients has not been definitively explored. We herein assessed how treatment strategies were decided based on FFR/iFR values in vessels selected clinically. Specifically, we sought to determine whether treatment selection was based on whether the vessel tested was the clinical target stenosis. METHODS: 270 consecutive patients with angiographically determined multivessel disease who underwent FFR/iFR testing were included...
April 2024: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38475298/synergistic-modification-of-polyformaldehyde-by-biobased-calcium-magnesium-bi-ionic-melamine-phytate-with-intumescent-flame-retardant
#9
JOURNAL ARTICLE
Shike Lu, Xueting Chen, Bin Zhang, Zhehong Lu, Wei Jiang, Xiaomin Fang, Jiantong Li, Baoying Liu, Tao Ding, Yuanqing Xu
Intumescent flame retardants (IFRs) are mainly composed of ammonium polyphosphate (APP), melamine (ME), and some macromolecular char-forming agents. The traditional IFR still has some defects in practical application, such as poor compatibility with the matrix and low flame-retardant efficiency. In order to explore the best balance between flame retardancy and mechanical properties of flame-retardant polyformaldehyde (POM) composite, a biobased calcium magnesium bi-ionic melamine phytate (DPM) synergist was prepared based on renewable biomass polyphosphate phytic acid (PA), and its synergistic system with IFRs was applied to an intumescent flame-retardant POM system...
February 23, 2024: Polymers
https://read.qxmd.com/read/38441988/coronary-physiology-instantaneous-wave-free-ratio-ifr-derived-from-x-ray-angiography-using-artificial-intelligence-deep-learning-models-a-pilot-study
#10
JOURNAL ARTICLE
Miguel Nobre Menezes, João Lourenço Silva, Beatriz Silva, Rita Marante de Oliveira, Tiago Rodrigues, Arlindo L Oliveira, Fausto J Pinto
OBJECTIVES: Coronary angiography (CAG)-derived physiology methods have been developed in an attempt to simplify and increase the usage of coronary physiology, based mostly on dynamic fluid computational algorithms. We aimed to develop a different approach based on artificial intelligence methods, which has seldom been explored. METHODS: Consecutive patients undergoing invasive instantaneous free-wave ratio (iFR) measurements were included. We developed artificial intelligence (AI) models capable of classifying target lesions as positive (iFR ≤ 0...
March 2024: Journal of Invasive Cardiology
https://read.qxmd.com/read/38370135/evaluation-of-an-augmented-reality-navigational-guidance-platform-for-percutaneous-procedures-in-a-cadaver-model
#11
JOURNAL ARTICLE
Gaurav Gadodia, Michael Evans, Crew Weunski, Amy Ho, Adam Cargill, Charles Martin
PURPOSE: The objective of this study is to review the accuracy of an augmented reality navigational guidance system designed to facilitate improved visualization, guidance, and accuracy during percutaneous needle-based procedures including biopsies and ablations. APPROACH: Using the HoloLens 2, the system registers and projects 3D CT-based models of segmented anatomy along with live ultrasound, fused with electromagnetically tracked instruments including ultrasound probes and needles, giving the operator comprehensive stereoscopic visualization for intraoperative planning and navigation during procedures...
November 2024: Journal of Medical Imaging
https://read.qxmd.com/read/38367040/validation-of-resting-full-cycle-ratio-and-diastolic-pressure-ratio-with-15-o-h-2-o-positron-emission-tomography%C3%A2-myocardial-perfusion
#12
JOURNAL ARTICLE
Jorge Dahdal, Frank Bakker, Johan Svanerud, Ibrahim Danad, Roel S Driessen, Pieter G Raijmakers, Hendrik J Harms, Adriaan A Lammertsma, Tim P van de Hoef, Yolande Appelman, Niels van Royen, Paul Knaapen, Guus A de Waard
Fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are invasive techniques used to evaluate the hemodynamic significance of coronary artery stenosis. These methods have been validated through perfusion imaging and clinical trials. New invasive pressure ratios that do not require hyperemia have recently emerged, and it is essential to confirm their diagnostic efficacy. The aim of this study was to validate the resting full-cycle ratio (RFR) and the diastolic pressure ratio (dPR), against [15 O]H2 O positron emission tomography (PET) imaging...
February 17, 2024: Heart and Vessels
https://read.qxmd.com/read/38344986/imaging-features-of-invasive-fungal-rhinosinusitis-a-systematic-review
#13
REVIEW
Anni Chen, James Pietris, Stephen Bacchi, WengOnn Chan, Alkis J Psaltis, Dinesh Selva, WanYin Lim
Fungal rhinosinusitis (FRS) includes non-invasive and invasive subtypes with the latter having significant morbidity and mortality. This systematic review aims to identify the imaging features most correlated with invasive fungal rhinosinusitis (IFRS) and present a checklist of these features to aid diagnosis. PubMed, Embase, CENTRAL, and Science Direct were searched from inception to May 2023, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines...
February 12, 2024: Canadian Association of Radiologists Journal
https://read.qxmd.com/read/38344391/sex-differences-in-5-year-outcomes-after-deferral-of-revascularization-following-physiological-coronary-assessment
#14
JOURNAL ARTICLE
Takayuki Ishihara, Shoichi Kuramitsu, Hitoshi Matsuo, Kazunori Horie, Hiroaki Takashima, Hidenobu Terai, Yuetsu Kikuta, Tatsuya Saigusa, Tomohiro Sakamoto, Nobuhiro Suematsu, Yasutsugu Shiono, Taku Asano, Kenichi Tsujita, Katsuhiko Masamura, Tatsuki Doijiri, Fumitoshi Toyota, Manabu Ogita, Tairo Kurita, Akiko Matsuo, Ken Harada, Kenji Yaginuma, Shinjo Sonoda, Hiroyoshi Yokoi, Nobuhiro Tanaka, Toshiaki Mano
Background: The relationship between sex differences and long-term outcomes after fractional flow reserve (FFR)- and instantaneous wave-free ratio (iFR)-guided deferral of revascularization has yet to be elucidated. Methods and Results: From the J-CONFIRM registry (long-term outcomes of Japanese patients with deferral of coronary intervention based on FFR in a multicenter registry), this study included 432 lesions from 385 patients (men, 323 lesions in 286 patients; women, 109 lesions in 99 patients) with paired data of FFR and iFR...
February 9, 2024: Circulation reports
https://read.qxmd.com/read/38231928/analyzing-temperature-distribution-patterns-on-the-facing-and-backside-surface-investigating-combustion-performance-of-flame-retardant-particle-boards-using-aluminum-hypophosphite-intumescent-and-magnesium-hydroxide-flame-retardants
#15
JOURNAL ARTICLE
Fangya Pan, Hongyu Jia, Yuxiang Huang, Zhilin Chen, Shanqing Liang, Peng Jiang
Particle boards are manufactured through a hot pressing process using wood materials (natural polymer materials) and adhesive, which find common usage in indoor decorative finishing materials. Flame-retardant particleboard, crucial for fire safety in such applications, undergoes performance analysis that includes assessing temperature distribution across its facing surface and temperature increase on the backside surface during facade combustion, yielding critical insights into fire scenario development. In this study, a compact flame spread apparatus is utilized to examine the flame retardancy and combustion behavior of particle boards, with a specific emphasis on the application of cost-effective flame retardants, encompassing aluminum hypophosphite (ALHP), an intumescent flame retardant (IFR) comprising ammonium polyphosphate (APP), melamine (MEL), and Dipentaerythritol (DPE), alongside magnesium hydroxide (MDH), and their associated combustion characteristics...
November 21, 2023: Polymers
https://read.qxmd.com/read/38223739/stakeholders-response-to-ifrs-adoption-convergence-on-accounting-quality-and-disclosures-a-bibliometric-review-of-scopus-database
#16
JOURNAL ARTICLE
Sakshi Bathla, Anil K Sharma, Vinay Kandpal
This study characterises the results of behavioral accounting research on International Financial Reporting Standards (IFRS) adoption published in various journals. It: (a) provides an integrated overview of the extant literature available on the Scopus database, (b) locates their contributions, (c) identifies knowledge gaps and (d) derives a unique hypothesis for future investigation. This review presents an analysis of the studies on IFRS adoption/convergence considering the response of various stakeholders to IFRS adoption on issues including accounting quality and disclosure requirements ...
January 15, 2024: Heliyon
https://read.qxmd.com/read/38215598/rationale-and-design-of-the-rapid-water-flow-trial-radiolabeled-perfusion-to-identify-coronary-artery-disease-using-water-to-evaluate-responses-of-myocardial-flow
#17
JOURNAL ARTICLE
Marcelo F Di Carli, Lars C Gormsen, Panithaya Chareonthaitawee, Geoffrey B Johnson, Rob Beanlands, Rob DeKemp, Thomas Schindler, Robert Gropler, Harshad Kulkarni, Parren McNeely, Prem Soman, Orhan Oz, Vlad Zaha, Jens Sorensen, Heinrich Harms, Cesare Orlandi, Emily Vandenbroucke, James Udelson
OBJECTIVES: The objective of this study was to determine the diagnostic performance of 15 O-water positron emission tomography (PET) myocardial perfusion imaging to detect coronary artery disease (CAD) using the truth-standard of invasive coronary angiography (ICA) with fractional flow reserve (FFR) or instantaneous wave-Free Ratio (iFR) or coronary computed tomography angiogram (CCTA). BACKGROUND: 15 O-water has a very high first-pass extraction that allows accurate quantification of myocardial blood flow and detection of flow-limiting CAD...
December 5, 2023: Journal of Nuclear Cardiology
https://read.qxmd.com/read/38199293/myocardial-bridges-in-a-pediatric-population-outcomes-following-a-standardized-approach
#18
JOURNAL ARTICLE
Tam T Doan, Carlos Bonilla-Ramirez, Lindsay Eilers, Dana Reaves-O'Neal, Shagun Sachdeva, Stephen J Dolgner, Prakash M Masand, Srinath Gowda, Athar M Qureshi, Ziyad Binsalamah, Silvana Molossi
OBJECTIVE: To describe clinical, functional, surgical, and outcomes data in pediatric patients with a myocardial bridge (MB) evaluated and managed following a standardized approach. METHODS: Prospective observational study included patients evaluated in the Coronary Artery Anomalies Program. Anatomy was determined by computed tomography angiography, myocardial perfusion by stress perfusion imaging, and coronary hemodynamic assessment by cardiac catheterization. RESULTS: A total of 39/42 patients with a complete evaluation for MB were included (12/2012-06/2022) at a median age of 14...
January 8, 2024: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/38194399/quad-net-quad-domain-network-for-ct-metal-artifact-reduction
#19
JOURNAL ARTICLE
Zilong Li, Qi Gao, Yaping Wu, Chuang Niu, Junping Zhang, Meiyun Wang, Ge Wang, Hongming Shan
Metal implants and other high-density objects in patients introduce severe streaking artifacts in CT images, compromising image quality and diagnostic performance. Although various methods were developed for CT metal artifact reduction over the past decades, including the latest dual-domain deep networks, remaining metal artifacts are still clinically challenging in many cases. Here we extend the state-of-the-art dual-domain deep network approach into a quad-domain counterpart so that all the features in the sinogram, image, and their corresponding Fourier domains are synergized to eliminate metal artifacts optimally without compromising structural subtleties...
January 9, 2024: IEEE Transactions on Medical Imaging
https://read.qxmd.com/read/38180036/major-adverse-cardiac-events-after-fractional-flow-reserve-instantaneous-wave-free-ratio-or-angiography-guided-revascularization-in-atrial-fibrillation-a-retrospective-study
#20
JOURNAL ARTICLE
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
No abstract text is available yet for this article.
January 15, 2024: American Journal of Cardiology
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