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https://www.readbyqxmd.com/read/28079740/venous-thromboembolism-among-pediatric-orthopedic-trauma-patients-a-database-analysis
#1
Daniel Guzman, Samir Sabharwal, Caixia Zhao, Sanjeev Sabharwal
Using the 2012 Kids Inpatient Database, we assessed records of pediatric patients (<21 years old) with fractures of the upper limb, lower limb, spine, pelvis, and multiple locations and calculated the overall prevalence of venous thromboembolism (VTE) and associated potential risk factors. 387 (0.68%) of 57 183 patients with one or more fractures were diagnosed with VTE. Children sustaining fractures of the axial skeleton and those with multiple fractures had a higher prevalence of VTE than those with isolated extremity fractures...
January 10, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28044426/children-after-renal-transplantation-hospitalized-for-fever-is-empirical-antibiotic-treatment-always-justified
#2
Liat Ashkenazi-Hoffnung, Miriam Davidovits, Efraim Bilavsky, Reem Yassin, Eran Rom, Jacob Amir
Infections are a major cause of morbidity and mortality after renal transplantation. However, data focusing on children are scarce. The objective of this study was to investigate the frequency and predictors of bacterial infection in pediatric renal transplant recipients in a specific setting of hospitalization due to fever. Clinical and laboratory data were retrospectively collected for all pediatric renal transplant recipients hospitalized for fever in a national renal transplantation center from 2004 to 2012...
January 2, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28011968/extended-spectrum-beta-lactamase-producing-enterobacteriaceae-among-the-pediatric-population-who-is-at-risk-and-why-results-from-a-single-centre-prospective-study
#3
Carmelina Calitri, Carlo Scolfaro, Sara Colombo, Gianfranco De Intinis, Francesca Carraro, Silvia Garazzino, Pier-Angelo Tovo
A prospective 18-month case-control study was performed in a tertiary Paediatric Centre in Turin (Italy) to analyse the disease burden and identify risk factors for acquisition of Extended Spectrum Beta Lactamase-producing Enterobacteriaceae (ESBL-pE). Children with ESBL-pE isolation were enrolled as cases, with controls matched according to age, type of pathogen isolated and sample of isolation. Out of 83 children (37 males, mean age 4.7 ± 5.46 years), 45 were identified as infected (54.2%) and 38 as colonised (45...
1, 2016: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/27994290/plasmapheresis-in-pediatric-intensive-care-unit
#4
Verica Misanovic, Danka Pokrajac, Smail Zubcevic, Admir Hadzimuratovic, Samra Rahmanovic, Selma Dizdar, Asmir Jonuzi, Edin Begic
INTRODUCTION: Plasmapheresis also known as a therapeutic plasma exchange (TPE) is extracorporeal procedure by which individual components of plasma that are harmful or blood cells can be removed from organism by using a blood separation technology. AIM: To present the results of the implementation of plasmapheresis in children in the Department of Pediatric Intensive Care of Pediatric Clinic, Clinical center of Sarajevo University, Bosnia and Herzegovina. PATIENTS AND METHODS: Research (period from December 2011 to June 2016) analyzed 66 plasmapheresis (11 patients-6 plasmapheresis per patient)...
October 2016: Medical Archives
https://www.readbyqxmd.com/read/27965360/screening-guidelines-for-venous-thromboembolism-risk-in-hospitalized-children-have-low-sensitivity-for-central-venous-catheter-associated-thrombosis
#5
Asfawossen B Asfaw, Rowena C Punzalan, Ke Yan, Raymond G Hoffmann, Sheila J Hanson
OBJECTIVES: Local pediatric screening guidelines for venous thromboembolism (VTE) are developed from incomplete pediatric data and extrapolated from adult data in which immobility is a major risk factor. We hypothesized that screening guidelines centered on immobility are inadequate for identifying children at risk of central venous catheter (CVC)-associated VTE. METHODS: This retrospective case-control (4:1) study at an academic, quaternary-level, free-standing children's hospital applied screening guidelines for VTE risk to all cases of VTE from July 2012 to April 2014...
January 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/27951558/evolution-of-technology-for-continuous-renal-replacement-therapy-forty-years-of-improvements
#6
Claudio Ronco
Continuous arteriovenous hemofiltration (CAVH) was proposed in 1977 as an alternative treatment for acute renal failure in patients in whom peritoneal dialysis or hemodialysis was clinically or technically precluded. In the mid-1980s, this technique was extended to infants and children. CAVH presented important advantages in the areas of hemodynamic stability, control of circulating volume, and nutritional support. However, there were serious shortcomings such as the need for arterial cannulation and limited solute clearance...
2017: Contributions to Nephrology
https://www.readbyqxmd.com/read/27942705/association-of-a-clinical-practice-guideline-with-blood-culture-use-in-critically-ill-children
#7
Charlotte Z Woods-Hill, James Fackler, Kristen Nelson McMillan, Judith Ascenzi, Diego A Martinez, Matthew F Toerper, Annie Voskertchian, Elizabeth Colantuoni, Sybil Ann Klaus, Scott Levin, Aaron M Milstone
Importance: Sepsis and septic shock are common and, at times, fatal in pediatrics. Blood cultures are often obtained when clinicians suspect sepsis, yet are low-yield with a false-positive rate up to 50%. Objectives: To determine whether a novel, 2-part, clinical practice guideline could decrease the rates of total blood cultures and cultures collected from central venous catheters in critically ill children and to examine the effect of the guideline on patient outcomes...
December 12, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27940695/intravenous-versus-oral-antibiotics-for-postdischarge-treatment-of-complicated-pneumonia
#8
Samir S Shah, Rajendu Srivastava, Susan Wu, Jeffrey D Colvin, Derek J Williams, Shawn J Rangel, Waheeda Samady, Suchitra Rao, Christopher Miller, Cynthia Cross, Caitlin Clohessy, Matthew Hall, Russell Localio, Matthew Bryan, Gong Wu, Ron Keren
BACKGROUND AND OBJECTIVES: Postdischarge treatment of complicated pneumonia includes antibiotics administered intravenously via a peripherally inserted central venous catheter (PICC) or orally. Antibiotics administered via PICC, although effective, may result in serious complications. We compared the effectiveness and treatment-related complications of postdischarge antibiotics delivered by these 2 routes. METHODS: This multicenter retrospective cohort study included children ≥2 months and <18 years discharged with complicated pneumonia between 2009 and 2012...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27918379/nontuberculous-mycobacteria-in-children-a-focus-on-bloodstream-infections
#9
Laila S Al Yazidi, Ben J Marais, Briony Hazelton, Alexander Outhred, Alison Kesson
BACKGROUND: Nontuberculous mycobacteria (NTM) are ubiquitous organisms with variable disease-causing potential. Bloodstream infections caused by NTM in children are poorly described. METHODS: We describe a retrospective case series of children with culture-confirmed mycobacterial disease managed at The Children's Hospital at Westmead from July 2005 - June 2015. RESULTS: Sixty-five patients had 149 positive NTM cultures; 55 (83.0%) episodes in 54 patients were considered clinically significant...
December 1, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27908433/central-venous-catheter-infections-in-home-parenteral-nutrition-patients-outcomes-from-sustain-american-society-for-parenteral-and-enteral-nutrition-s-national-patient-registry-for-nutrition-care
#10
Vicki M Ross, Peggi Guenter, Mandy L Corrigan, Debra Kovacevich, Marion F Winkler, Helaine E Resnick, Tina L Norris, Lawrence Robinson, Ezra Steiger
BACKGROUND: Home parenteral nutrition (HPN) is a high-cost, complex nutrition support therapy that requires the use of central venous catheters. Central line-associated bloodstream infections (CLABSIs) are among the most serious risks of this therapy. Sustain: American Society for Parenteral and Enteral Nutrition's National Patient Registry for Nutrition Care (Sustain registry) provides the most current and comprehensive data for studying CLABSI among a national cohort of HPN patients in the United States...
December 1, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27865217/-multidimensional-strategy-regarding-the-reduction-of-central-line-associated-infection-in-pediatric-intensive-care
#11
Jorge Rodrigues, Andrea Dias, Guiomar Oliveira, José Farela Neves
INTRODUCTION: To determine the central-line associated bloodstream infection rate after implementation of central venous catheter-care practice bundles and guidelines and to compare it with the previous central-line associated bloodstream infection rate. MATERIAL AND METHODS: A prospective, longitudinal, observational descriptive study with an exploratory component was performed in a Pediatric Intensive Care Unit during five months. The universe was composed of every child admitted to Pediatric Intensive Care Unit who inserted a central venous catheter...
June 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/27822085/danish-childhood-cancer-registry
#12
REVIEW
Henrik Schrøder, Catherine Rechnitzer, Peder Skov Wehner, Steen Rosthøj, Jens Kjølseth Møller, Birgitte Lausen, Gitte Petersen, Mette Nørgaard
AIM OF DATABASE: The overall aim is to monitor the quality of childhood cancer care in Denmark; to register late effects of treatment; to analyze complications of permanent central venous catheters (CVCs); to study blood stream infections in children with cancer; and to study acute toxicity of high-dose methotrexate infusions in children with leukemia. STUDY POPULATION: All children below 15 years of age at diagnosis living in Denmark diagnosed after January 1, 1985 according to the International Classification of Diseases 10, including diagnoses DC00-DD48...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27786416/does-guidewire-exchange-influence-infection-rate-related-to-catheters-used-for-vascular-access-in-children-on-chronic-hemodialysis
#13
Rina R Rus, Nina Battelino, Rafael Ponikvar, Vladimir Premru, Gregor Novljan
A central venous catheter (CVC) can either be inserted "de novo" or placed by guidewire exchange (GWE). From September 1998 to September 2015, 32 children (19 boys, 13 girls) were hemodialyzed in our unit by using a CVC. The mean age at CVC insertion was 12.6 ± 0.5 years. A total of 121 uncuffed catheters were placed, either "de novo" or by GWE in 64 (52.9%) and 57 (47.1%) cases, respectively. The most frequent cause for line revision was catheter dysfunction in 40/121 (33.1%) patients. The overall incidence of bacteremia was 1...
October 27, 2016: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/27765663/comprehensive-technical-and-patient-care-optimization-in-the-management-of-pediatric-apheresis-for-peripheral-blood-stem-cell-harvesting
#14
Yoshihiro Ohara, Hitoshi Ohto, Tetsunori Tasaki, Hideki Sano, Kazuhiro Mochizuki, Mitsuko Akaihata, Shogo Kobayashi, Tomoko Waragai, Masaki Ito, Mitsuaki Hosoya, Kenneth E Nollet, Kazuhiko Ikeda, Chitose Ogawa, Takahiro Kanno, Yayoi Shikama, Atsushi Kikuta
BACKGROUND: Pediatric apheresis for peripheral blood stem cell transplantation should be carried out with due concern for low corporeal blood volume and vulnerability to hypocalcemia-related complications, hypovolemic shock, and hypervolemic cardiac overload. STUDY DESIGN AND METHODS: We retrospectively investigated a total of 267 apheresis procedures from 1990 to 2013 on 93 children between 0 and 10 years old, including 89 patients and 4 healthy donors, with body weights of 6...
December 2016: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/27743023/a-technique-for-re-utilizing-catheter-insertion-sites-in-children-with-difficult-central-venous-access
#15
S M Johnson, G M Garnett, R K Woo
Maintenance of central venous access in patients with chronic medical conditions such as short bowel syndrome demands forethought and ingenuity. We describe an innovative technique for re-utilizing central venous access sites in patients who have chronic central venous access needs. Records of patients undergoing this technique were reviewed between August 2012 and December 2015. The technique involves "cutting-down" to the sterile fibrous tunnel that naturally forms around tunneled catheters. The fibrous sheath is then isolated and controlled much as would be done for a venous "cut-down...
October 14, 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27740892/contemporary-insertion-of-central-venous-access-catheters-in-pediatric-patients-a-retrospective-record-review-study-of-538-catheters-in-a-single-center
#16
Max B van Gent, Wendeline J van der Made, Perla J Marang-van de Mheen, Koen E van der Bogt
OBJECTIVE: To analyze the rate of infections and complications after surgeon-performed, largely ultrasound-guided, central venous catheter (CVC) placement in a pediatric population and to identify patients at high risk of complications. METHODS: All children aged between 4 months and 19 years with a percutaneous CVC inserted between January 1, 2000, and July 31, 2013, were included. Patient records were reviewed retrospectively for the occurrence of infection and other complications until CVC removal or the last outpatient clinic visit and compared between patient groups and with the recent literature...
October 14, 2016: Surgical Infections
https://www.readbyqxmd.com/read/27699158/outcomes-of-arteriovenous-fistula-for-hemodialysis-in-pediatric-and-adolescent-patients
#17
Suh Min Kim, Seung-Kee Min, Sanghyun Ahn, Sang-Il Min, Jongwon Ha
PURPOSE: This retrospective review aimed to report the outcomes of arteriovenous fistula (AVF) and to evaluate the suitability of AVF as a permanent vascular access in pediatric populations. MATERIALS AND METHODS: Data were collected for all patients aged 0 to 19 years who underwent AVF creation for hemodialysis between January 2000 and June 2014. RESULTS: Fifty-two AVFs were created in 47 patients. Mean age was 15.7±3.2 years and mean body weight was 46...
September 2016: Vascular Specialist International
https://www.readbyqxmd.com/read/27695218/hickman-to-central-venous-catheter-a-case-of-difficult-venous-access-in-a-child-suffering-from-acute-lymphoblastic-leukemia
#18
Arunangshu Chakraborty, Sanjit Agrawal, Taniya Datta, Suparna Mitra, Rakhi Khemka
Chemotherapy in children suffering from cancer usually requires placement of an indwelling central venous catheter (CVC). A child may need to undergo repeated procedures because of infection and occlusion of previous access devices. We present a case of CVC insertion in a child suffering from acute lymphoblastic leukemia where an innovative technique was employed.
October 2016: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/27688016/probiotics-for-the-prevention-of-pediatric-antibiotic-associated-diarrhea
#19
Shelby R Hayes, Ashley J Vargas
: Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, Johnston BC. Probiotics for the prevention of pediatric antibiotic-associated diarrhea.Cochrane Database Syst Rev2015, Issue 12. Art. No.: CD004827. http://dx.doi.org/10.1002/14651858.CD004827.pub4. BACKGROUND: Antibiotics are frequently prescribed in children. They alter the microbial balance within the gastrointestinal tract, commonly resulting in antibiotic-associated diarrhea (AAD). Probiotics may prevent AAD via restoration of the gut microflora...
November 2016: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/27679966/current-state-of-pediatric-intensive-care-and-high-dependency-care-in-nepal
#20
Aayush Khanal, Arun Sharma, Sangita Basnet
OBJECTIVES: To describe the state of pediatric intensive care and high dependency care in Nepal. Pediatric intensive care is now a recognized specialty in high-income nations, but there are few reports from low-income countries. With the large number of critically ill children in Nepal, the importance of pediatric intensive care is increasingly recognized but little is known about its current state. DESIGN: Survey. SETTING: All hospitals in Nepal that have separate physical facilities for PICU and high dependency care...
November 2016: Pediatric Critical Care Medicine
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