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https://www.readbyqxmd.com/read/28344217/left-ventricular-twist-was-decreased-in-isolated-left-bundle-branch-block-with-preserved-ejection-fraction
#1
Sabiye Yılmaz, Harun Kılıc, Mustafa Tarık Ağac, Nurgül Keser, Efe Edem, Saadet Demirtaş, Mehmet Bülent Vatan, Ramazan Akdemir, Hüseyin Gündüz
OBJECTIVE: Left ventricular (LV) rotation and twist play an important role in LV contraction and relaxation. Left bundle branch block (LBBB) deteriorates both diastolic and systolic functions. We evaluated the LV twist in patients with LBBB and preserved ejection fraction (EF) (>50%) to determine twist as a potential marker for subtle myocardial dysfunction. METHODS: This observational cross-sectional study included 34 LBBB patients with preserved EF who were free from ischemic and valvular disease (Group 1) and 36 healthy controls (Group 2)...
March 22, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28337725/comparison-of-diagnostic-performance-of-four-software-packages-for-phase-dyssynchrony-analysis-in-gated-myocardial-perfusion-spect
#2
Koichi Okuda, Kenichi Nakajima, Shinro Matsuo, Soichiro Kashiwaya, Hiroto Yoneyama, Takayuki Shibutani, Masahisa Onoguchi, Mitsumasa Hashimoto, Seigo Kinuya
BACKGROUND: Phase analysis of gated myocardial perfusion single-photon emission computed tomography (SPECT) for assessment of left ventricular (LV) dyssynchrony was investigated using the following dedicated software packages: Corridor4DM (4DM), cardioREPO (cREPO), Emory Cardiac Toolbox (ECTb), and quantitative gated SPECT (QGS). The purpose of this study was to evaluate the normal values of 95% histogram bandwidth, phase standard deviation (SD), and entropy and to compare the diagnostic performance of the four software packages...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28335644/heart-rate-and-dyssynchrony-in-patients-with-cardiac-resynchronization-therapy-a-pilot-study
#3
Jan Naar, Lars Mortensen, Reidar Winter, Jonas Johnson, Kambiz Shahgaldi, Aristomenis Manouras, Frieder Braunschweig, Marcus Ståhlberg
OBJECTIVES: The objective of this pilot study was to describe the impact of paced heart rate on left ventricular (LV) mechanical dyssynchrony in synchronous compared to dyssynchronous pacing modes in patients with heart failure. METHODS: Echocardiography was performed in 14 cardiac resynchronization therapy (CRT) patients at paced heart rates of 70 and 90 bpm in synchronous- (CRT), and dyssynchronous (atrial pacing + wide QRS activation) pacing modes. LV dyssynchrony was quantified using the 12-segment standard deviation model (Ts-SD) derived from Tissue Doppler Imaging...
March 23, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/28332315/significant-increase-of-flow-kinetic-energy-in-nonresponders-patients-to-cardiac-resynchronization-therapy
#4
Sara Cimino, Dino Palombizio, Francesco Cicogna, Donatella Cantisani, Manuela Reali, Domenico Filomena, Valentina Petronilli, Carlo Iacoboni, Luciano Agati
BACKGROUNDS: It's still unclear if different patterns of intraventricular flow dynamics may be detected in patients nonresponders to cardiac resynchronization therapy (CRT) as compared to responders ones. Aim of this study was to evaluate the characteristics of left ventricular (LV) flow dynamics 6-months after CRT to identify Echo-particle imaging velocity (PIV) patterns were more frequently detected in nonresponders patients. METHODS: Thirty-two patients with dilated cardiomyopathy, undergoing CRT, were enrolled in this study...
March 23, 2017: Echocardiography
https://www.readbyqxmd.com/read/28329299/rational-and-design-of-eurocrt-an-international-observational-study-on-multi-modality-imaging-and-cardiac-resynchronization-therapy
#5
Erwan Donal, Victoria Delgado, Julien Magne, Chiara Bucciarelli-Ducci, Christophe Leclercq, Bernard Cosyns, Marta Sitges, Thor Edvardsen, Elif Sade, Ivan Stankovic, Eustachio Agricola, Maurizio Galderisi, Patrizio Lancellotti, Alfredo Hernandez, Sven Plein, Denisa Muraru, Ehud Schwammenthal, Gerhard Hindricks, Bogdan A Popescu, Gilbert Habib
Aims: Assessment of left ventricular (LV) volumes and ejection fraction (LVEF) with cardiac imaging is important in the selection of patients for cardiac resynchronization therapy (CRT). Several observational studies have explored the role of imaging-derived LV dyssynchrony parameters to predict the response to CRT, but have yielded inconsistent results, precluding the inclusion of imaging-derived LV dyssynchrony parameters in current guidelines for selection of patients for CRT. METHODS: The EuroCRT is a large European multicentre prospective observational study led by the European Association of Cardiovascular Imaging...
February 27, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28322009/prognostic-importance-of-left-ventricular-mechanical-dyssynchrony-in-heart-failure-with-preserved-ejection-fraction
#6
Tor Biering-Sørensen, Sanjiv J Shah, Inder Anand, Nancy Sweitzer, Brian Claggett, Li Liu, Bertram Pitt, Marc A Pfeffer, Scott D Solomon, Amil M Shah
AIMS: Left ventricular mechanical dyssynchrony has been described in heart failure with preserved ejection fraction (HFpEF), but its prognostic significance is not known. METHODS AND RESULTS: Of 3445 patients with HFpEF enrolled in the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial, dyssynchrony analysis was performed on 424 patients (12%) by multiple speckle tracking echocardiography strain-based criteria. The primary dyssynchrony analysis was the standard deviation of the time to peak longitudinal strain (SD T2P LS)...
March 21, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28318481/simultaneous-total-cavopulmonary-connection-and-cardiac-re-synchronisation-therapy
#7
Keisuke Nakanishi, Shiori Kawasaki, Atsushi Amano
We report the simultaneous use of cardiac re-synchronisation therapy and total cavopulmonary connection in a patient with dyssynchrony, wide QRS, and cardiac failure. To our knowledge, this simultaneous approach has not been reported previously. On follow-up, we noted that QRS width and brain natriuretic peptide levels improved. In addition, speckle tracking revealed improved synchronisation of ventricular wall motion.
March 20, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28317170/added-clinical-value-of-applying-myocardial-deformation-imaging-to-assess-right-ventricular-function
#8
REVIEW
Vladislavs Sokalskis, Diletta Peluso, Annika Jagodzinski, Christoph Sinning
Right heart dysfunction has been found to be a strong prognostic factor predicting adverse outcome in various cardiopulmonary diseases. Conventional echocardiographic measurements can be limited by geometrical assumptions and impaired reproducibility. Speckle tracking-derived strain provides a robust quantification of right ventricular function. It explicitly evaluates myocardial deformation, as opposed to tissue Doppler-derived strain, which is computed from tissue velocity gradients. Right ventricular longitudinal strain provides a sensitive tool for detecting right ventricular dysfunction, even at subclinical levels...
March 19, 2017: Echocardiography
https://www.readbyqxmd.com/read/28317064/altered-synchrony-of-right-ventricular-contraction-in-borderline-pulmonary-hypertension
#9
Bouchra Lamia, Jean-François Muir, Luis-Carlos Molano, Catherine Viacroze, Jacques Benichou, Philippe Bonnet, Jean Quieffin, Antoine Cuvelier, Robert Naeije
Imaging studies have shown that pulmonary hypertension (PH) is associated with inhomogenous right ventricular (RV) regional contraction, or dyssynchrony, and that this is of prognostic relevance. This study aimed at the identification and functional significance of RV dyssynchrony in borderline PH defined by a mean pulmonary artery pressure between (mPAP) 20 and 25 mmHg. RV dyssynchrony was measured by 2-dimensional speckle tracking echocardiography in 17 patients with pulmonary arterial hypertension (PAH), 13 patients with borderline PH and 14 controls...
March 19, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28315562/improvement-in-left-ventricular-intrinsic-dyssynchrony-with-cardiac-resynchronization-therapy
#10
Serdar Bozyel, Ayşen Ağaçdiken Ağır, Tayfun Şahin, Umut Çelikyurt, Müjdat Aktaş, Onur Argan, İrem Yılmaz, Kurtuluş Karaüzüm, Emir Derviş, Ahmet Vural, Dilek Ural
OBJECTIVE: Cardiac resynchronization therapy (CRT) has been shown to induce a structural and electrical remodeling; the data on whether left ventricle (LV) reverse remodeling is associated with restitution of intrinsic contraction pattern are unknown. In this study, we investigated the presence of improvement in left ventricular intrinsic dyssynchrony in patients with CRT. METHODS: A total of 45 CRT recipients were prospectively studied. Dyssynchrony indexes including interventricular mechanical delay (IVMD) and tissue Doppler velocity opposing-wall delay (OWD) as well as QRS duration on 12-lead surface electrocardiogram were recorded before CRT device implantation...
March 3, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28290786/-predictors-of-heart-failure-with-preserved-ejection-fraction-in-patients-with-metabolic-syndrome-and-preclinical-diastolic-dysfunction
#11
K G Adamyan, L G Tunyan, A L Chilingaryan, L R Tumasyan
PURPOSE: to evaluate differences in echocardiographic parameters between patients with preclinical diastolic dysfunction (PDD) and heart failure with preserved ejection fraction (HFpEF) and to identify predictors of transition from PDD to HFpEF. MATERIAL AND METHODS: Echocardiographic parameters were recorded in 325 patients with PDD and 50 healthy subjects. PDD and HFpEF were diagnosed by tissue Doppler imaging of the left ventricle (LV) during exercise stress test and detection of symptoms of heart failure...
February 2017: Kardiologiia
https://www.readbyqxmd.com/read/28274575/relation-of-myocardial-contrast-enhanced-t1-mapping-by-cardiac-magnetic-resonance-to-left-ventricular-reverse-remodeling-after-cardiac-resynchronization-therapy-in-patients-with-nonischemic-cardiomyopathy
#12
Ulas Höke, Mand J H Khidir, Rob J van der Geest, Martin J Schalij, Jeroen J Bax, Victoria Delgado, Nina Ajmone Marsan
Myocardial scar is known to be associated with limited left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). However, the impact of diffuse myocardial interstitial fibrosis, as assessed with myocardial T1 mapping cardiac magnetic resonance (CMR), has not been studied in patients with CRT. Therefore, we aimed at evaluating the association between diffuse myocardial interstitial fibrosis, in nonischemic cardiomyopathy patients, and LV reverse remodeling after CRT. A total of 40 patients (61 ± 11 years) with nonischemic cardiomyopathy who underwent CMR before CRT implantation were included...
February 9, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28269193/dynamic-mapping-of-ventricular-function-from-cardiovascular-magnetic-resonance-imaging
#13
Maria Panayiotou, Peter Mountney, Alexander Brost, Daniel Toth, Tom Jackson, Jonathan M Behar, Christopher A Rinaldi, R James Housden, Kawal S Rhode
Heart failure is associated with substantial mortality and morbidity and remains the most common diagnosis in older patients. Based on experimental electrophysiologic studies, cardiac resynchronization therapy (CRT) for heart failure results in a maximum resynchronization effect when applied to the most delayed left ventricular (LV) site. Current clinical practice is to identify the optimal site using separate visualisation of scar and activation information. These must be mentally mapped into 3D, which is challenging and time-consuming for the electrophysiologist...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28262302/contraction-timing-patterns-in-patients-treated-for%C3%A2-breast-cancer-before-and-after-anthracyclines%C3%A2-therapy
#14
Kai-Hung Cheng, Mark D Handschumacher, Bruna Morhy Borges Leal Assuncao, Igal A Sebag, Elkan F Halpern, Marielle Scherrer-Crosbie
BACKGROUND: During the development of heart failure (HF), the changes of contraction timing pattern and temporal heterogeneity of segmental contraction happen early and may precede both symptomatic HF and the decrease in left ventricular ejection fraction (LVEF). In patients treated with anthracyclines, both symptomatic HF and the decrease of LVEF are detected once significant myocardial injury has occurred. The aim of the current study was to investigate whether changes in the timing of contraction can be detected early after anthracyclines therapy...
March 2, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28247588/atrioventricular-dyssynchrony-from-empiric-device-settings-is-common-in-cardiac-resynchronization-therapy-and-adversely-impacts-left-ventricular-morphology-and-function
#15
Gregory J Sinner, Vedant A Gupta, Arash Seratnahaei, Richard J Charnigo, Yousef H Darrat, Samy C Elayi, Steve W Leung, Vincent L Sorrell
BACKGROUND: Echocardiographic atrioventricular (AV) optimization after cardiac resynchronization therapy (CRT) is uncommon due to time constraints and the use of vendor-specific device algorithms. It remains unclear whether optimization of mitral inflow velocities can still be useful. We aimed to investigate post implantation left ventricular (LV) inflow patterns to determine the incidence of AV dyssynchrony from empirically set devices. METHODS: This was a retrospective study of patients undergoing CRT using empiric device settings...
March 1, 2017: Echocardiography
https://www.readbyqxmd.com/read/28243894/total-thoracoscopic-left-ventricular-lead-implantation-for-hybrid-cardiac-resynchronization-therapy-in-pacemaker-mediated-cardiomyopathy
#16
Yu Inaba, Tsutomu Ito, Sachiko Hayashi, Tatsuo Takahashi, Yoshimasa Inoue, Teruhiro Aoki, Hideyuki Takimura, Tsuyoshi Sakai, Takahiko Misumi, Hideyuki Shimizu
Cardiac resynchronization therapy (CRT) has been increasingly performed in patients having heart failure with dyssynchrony. We report a successful case of total thoracoscopic left ventricular (LV) lead implantation in CRT. A 77-year-old man with marked dyssynchrony of the LV wall motion and a low ejection fraction (EF17%) due to pacemaker-mediated cardiomyopathy was referred to us. CRT was planned, but percutaneous LV lead implantation proved difficult owing to anatomical variations. The LV lead was placed in the post-lateral wall of the LV base using a total thoracoscopic procedure...
February 28, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28240425/assessment-of-left-atrial-mechanical-function-and-synchrony-in-paroxysmal-atrial-fibrillation-with-two-dimensional-speckle-tracking-echocardiography
#17
Zhijuan Shang, Dechun Su, Tao Cong, Yinghui Sun, Yan Liu, Na Chen, Jun Yang
BACKGROUND: The aim of this study was to investigate left atrial (LA) function and synchrony in paroxysmal atrial fibrillation (PAF) patients using two-dimensional speckle tracking echocardiography (STE). METHODS: Forty-five PAF patients and 30 healthy controls were enrolled. LA peak ventricular systolic longitudinal strain (LAS-S ) and strain rate (LASR-S ) and left atrial longitudinal strain (LAS-A ) and strain rate (LASR-A ) during late diastole were determined using STE, and the standard deviation of the time to peak (TPSD) of the regional strains was calculated to quantify LA dyssynchrony...
February 2017: Echocardiography
https://www.readbyqxmd.com/read/28238564/impact-of-persistent-left-ventricular-regional-wall-motion-abnormalities-in-childhood-cancer-survivors-after-anthracycline-therapy-assessment-of-global-left-ventricular-myocardial-performance-by-3d-speckle-tracking-echocardiography
#18
Hirotsugu Okuma, Nobutaka Noto, Syuntaro Tanikawa, Koji Kanezawa, Maiko Hirai, Katsuyoshi Shimozawa, Hiroshi Yagasaki, Hiroyuki Shichino, Shori Takahashi
AIMS: To identify left ventricular (LV) mechanical impairment by 3D speckle-tracking echocardiography (3DSTE) in long-term childhood cancer survivors after anthracycline therapy with or without persistent LV regional diastolic wall motion abnormalities (WMA) and a preserved LV ejection fraction (EF >53%). METHODS AND RESULTS: Thirty-two patients (median: 14.6 years) and 12 age-matched controls were studied. The patients were divided into two groups according to the existence of WMA: Group 1 (with WMA: n=14), Group 2 (without WMA: n=18)...
February 23, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28227423/dynamic-mapping-of-ventricular-function-from-cardiovascular-magnetic-resonance-imaging
#19
Maria Panayiotou, Peter Mountney, Alexander Brost, Daniel Toth, Tom Jackson, Jonathan M Behar, Christopher A Rinaldi, R James Housden, Kawal S Rhode, Maria Panayiotou, Peter Mountney, Alexander Brost, Daniel Toth, Tom Jackson, Jonathan M Behar, Christopher A Rinaldi, R James Housden, Kawal S Rhode, Alexander Brost, Tom Jackson, Maria Panayiotou, Christopher A Rinaldi, Jonathan M Behar, R James Housden, Kawal S Rhode, Daniel Toth, Peter Mountney
Heart failure is associated with substantial mortality and morbidity and remains the most common diagnosis in older patients. Based on experimental electrophysiologic studies, cardiac resynchronization therapy (CRT) for heart failure results in a maximum resynchronization effect when applied to the most delayed left ventricular (LV) site. Current clinical practice is to identify the optimal site using separate visualisation of scar and activation information. These must be mentally mapped into 3D, which is challenging and time-consuming for the electrophysiologist...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222749/the-impact-of-trans-catheter-aortic-valve-replacement-induced-left-bundle-branch-block-on-cardiac-reverse-remodeling
#20
Laura E Dobson, Tarique A Musa, Akhlaque Uddin, Timothy A Fairbairn, Owen J Bebb, Peter P Swoboda, Philip Haaf, James Foley, Pankaj Garg, Graham J Fent, Christopher J Malkin, Daniel J Blackman, Sven Plein, John P Greenwood
BACKGROUND: Left bundle branch block (LBBB) is common following trans-catheter aortic valve replacement (TAVR) and has been linked to increased mortality, although whether this is related to less favourable cardiac reverse remodeling is unclear. The aim of the study was to investigate the impact of TAVR induced LBBB on cardiac reverse remodeling. METHODS: 48 patients undergoing TAVR for severe aortic stenosis were evaluated. 24 patients with new LBBB (LBBB-T) following TAVR were matched with 24 patients with a narrow post-procedure QRS (nQRS)...
February 22, 2017: Journal of Cardiovascular Magnetic Resonance
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