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sentinel node biopsy

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https://www.readbyqxmd.com/read/27910800/routine-x-ray-of-the-chest-is-not-justified-in-staging-of-cutaneous-melanoma-patients
#1
Caroline Asirvatham Gjørup, Helle Westergren Hendel, Rita Kaae Pilegaard, Cecilie Balslev Willert, Lisbet Rosenkrantz Hölmich
INTRODUCTION: The incidence of cutaneous melanoma is increasing in Denmark and worldwide. However, the prevalence of distant metastases at the time of diagnosis has decreased to 1%. We therefore questioned the value of routine preoperative chest X-ray (CXR) for staging asymptomatic melanoma patients and hypothesised that routine CXR is not justified. METHODS: A retrospective study was conducted on patients undergoing wide local excision and sentinel lymph node biopsy for cutaneous melanoma in the period from 2010 to 2014...
December 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27906694/follicular-malignant-melanoma-a-rare-morphologic-variant-of-melanoma-report-of-a-case-and-review-of-the-literature
#2
Iona Chapman, Sharon Horton, Wenhua Liu
Follicular malignant melanoma (FMM) is an exceedingly rare variant of melanoma. Only 8 cases have been reported in the literature thus far. Often bland on physical examination, FMM shows a striking histologic pattern, with atypical melanocytes sometimes consuming the entire follicle and extending into the dermis. Criteria have been suggested to help distinguish FMM from lentigo maligna melanoma; however, no clear criteria distinguish this cancer clinically. FMM cannot be distinguished from follicular metastases of melanoma based on histology, requiring close clinical correlation and detailed history taking on the part of the practitioner...
November 29, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27905950/use-of-indocyanine-green-and-the-hypereye-system-for-detecting-sentinel-lymph-nodes-in-breast-cancer-within-a-population-of-european-patients-a-pilot-study
#3
Oldřich Coufal, Vuk Fait
BACKGROUND: Certain studies suggest that using indocyanine green (ICG) could be comparable with using radioisotopes (RI) in detecting sentinel lymph nodes (SLNs) in breast cancer. A number of these studies were performed in Asia. The objective of our pilot study was to evaluate within a European population of breast cancer patients the detection rate of SLNs using ICG and the HyperEye system and the concordance in SLNs detected using this method and the standard method involving RI and a gamma probe...
December 1, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27904514/intraoperative-diagnosis-of-sentinel-lymph-node-metastases-in-breast-cancer-treatment-with-one-step-nucleic-acid-amplification-assay-osna
#4
Paweł Szychta, Bogusław Westfal, Rafał Maciejczyk, Beata Smolarz, Hanna Romanowicz, Tomasz Krawczyk, Marek Zadrożny
INTRODUCTION: The aim of the study was to evaluate the clinical usefulness of a one-step nucleic acid amplification assay (OSNA) for intraoperative detection of metastases to sentinel lymph nodes (SLNs) in comparison to examination of frozen sections, and to summarize the results of previous studies. MATERIAL AND METHODS: We enrolled 98 patients aged 58.13 ±10.74 years treated surgically for breast cancer, and 99 biopsies of SLNs were followed by analysis of 105 SLNs...
December 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27900818/healthcare-costs-reduced-after-incorporating-the-results-of-the-american-college-of-surgeons-oncology-group-z0011-trial-into-clinical-practice
#5
Michelle M Fillion, Katherine E Glass, Joe Hayek, Allison Wehr, Gary Phillips, Alicia Terando, Doreen M Agnese
The purpose of our study was to quantitate the changes in axillary lymph node dissection (ALND), frozen section (FS), and the impact on costs after the publication of the American College of Surgeons Oncology Group (ACOSOG) Z0011 trial. We compared axillary nodal management and cost data in breast cancer patients who met Z0011 criteria and were treated with lumpectomy and sentinel lymph nodes (SLN) biopsy from 2007 to July 2013. Of 800 patients, 67 (13.5%) and 34 (12.5%) patients in the pre- and post-Z0011 era had 1-2 positive SLN...
November 30, 2016: Breast Journal
https://www.readbyqxmd.com/read/27900755/incidental-18f-fdg-pet-ct-bilateral-breast-uptake-due-to-carcinoma
#6
Domenico Albano, Mattia Bertoli, Maria Laura Morassi, Giovanni Bosio, Emanuela Orlando, Francesco Bertagna
We report a case of 71-year-old female patient, previously treated with chemotherapy and surgical resection of sigmoid tract of the large bowel for adenocarcinoma (pT3N1M0), who underwent a 18F-FDG PET/CT for a suspicious hepatic lesion detected at CT scan during follow-up. 18F-FDG PET/CT showed no abnormal uptake in the liver both at 60 minutes and 120 minutes after injection but revealed a pathological uptake in two breast nodules, (one localized in upper-internal-quadrant of the right breast and the other in the upper-external-quadrant of the left breast)...
2016: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/27898616/the-role-for-sentinel-lymph-node-biopsy-in-the-management-of-conjunctival-melanoma
#7
Jeanie Ling, Robert Tauscher, Viraj Mehta, Matthew Zhang, Anthony Daniels, Sahar Kohanim
No abstract text is available yet for this article.
2017: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/27896640/role-of-axillary-ultrasound-magnetic-resonance-imaging-and-ultrasound-guided-fine-needle-aspiration-biopsy-in-the-preoperative-triage-of-breast-cancer-patients
#8
I Barco, C Chabrera, A García-Fernández, M Fraile, S González, L Canales, J M Lain, C González, M C Vidal, E Vallejo, J Deu, A Pessarrodona, N Giménez, M García Font
PURPOSE: Roughly two-thirds of early breast cancer cases are associated with negative axillary nodes and do not benefit from axillary surgery at all. Accordingly, there is an ongoing search for non-surgical staging procedures to avoid lymph-node dissection or sentinel node biopsy (SNB). Non-invasive imaging techniques with very high sensitivity (Se) and negative predictive value (NPV) could eventually replace SNB. We aimed to establish the role of axillary US and MRI, alone or in combination, associated with ultrasound-guided fine-needle aspiration biopsy (US-FNAB) in the prediction of axillary node involvement...
November 28, 2016: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/27894166/the-detection-of-sentinel-lymph-nodes-in-laparoscopic-surgery-for-uterine-cervical-cancer-using-99m-technetium-tin-colloid-indocyanine-green-and-blue-dye
#9
Tomohito Tanaka, Yoshito Terai, Keisuke Ashihara, Satoshi Tsunetoh, Hiroyuki Akagi, Takashi Yamada, Masahide Ohmichi
OBJECTIVE: Our objective was to determine the feasibility and detection rates and clarify the most effective combination of injected tracer types for sentinel lymph node (SLN) mapping in uterine cervical cancer in patients who have undergone laparoscopic surgery or neoadjuvant chemotherapy (NAC). METHODS: A total of 119 patients with cervical cancer underwent SLN biopsy at radical hysterectomy using three types of tracers. The various factors related to side-specific detection rate, sensitivity, and false negative (FN) rate were analyzed...
November 1, 2016: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/27893540/eight-years-experience-of-sentinel-lymph-node-biopsy-in-melanoma-using-lymphoscintigraphy-and-gamma-probe-detection-after-radiocolloid-mapping
#10
Nathalie Pham Dang, Sophie Cassier, Aurélien Mulliez, Sandrine Mansard, Michel DʼIncan, Isabelle Barthélémy
BACKGROUND: Isosulfan blue dye peripheral injection is used in preoperative sentinel lymph node (SLN) identification alone or, to increase sensitivity, in conjunction with radiocolloid mapping. However, isosulfan blue dye has certain drawbacks and limitations. OBJECTIVE: This study assesses the authors' experience of SLN biopsy using only radiocolloid tracer. MATERIALS AND METHODS: Between 2000 and 2008, 218 patients underwent SLN biopsy with radiocolloid mapping, preoperative localization by lymphoscintigraphy and intraoperative confirmation by gamma probe in primary malignant cutaneous melanoma...
November 23, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27889596/using-ultrasound-and-palpation-for-predicting-axillary-lymph-node-status-following-neoadjuvant-chemotherapy-results-from-the-multi-center-sentina-trial
#11
Lukas Schwentner, Gisela Helms, Valentina Nekljudova, Beyhan Ataseven, Ingo Bauerfeind, Nina Ditsch, Tanja Fehm, Barbara Fleige, Maik Hauschild, J Heil, Sherko Kümmel, Anette Lebeau, Sabine Schmatloch, Peter Schrenk, Anette Staebler, Sibylle Loibl, Michael Untch, Gunter Von Minckwitz, Cornelia Liedtke, Thorsten Kühn
BACKGROUND: With the growing importance of neoadjuvant systemic therapy (NST) the assessment of post neoadjuvant axillary status is of increasing importance especially in patients who presented initially with suspicious nodes (cN1). This study aims to investigate the predictive value of palpation and axillary ultrasound of formerly cN1 patients following NST. PATIENTS AND METHODS: The SENTINA trial (SENTinel NeoAdjuvant) is a 4-arm prospective multicenter study designed to evaluate the role of sentinel node biopsy (SLNB) in the context of neoadjuvant systemic treatment (NST) of breast cancer patients...
November 24, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27882757/-contribution-of-sentinel-lymph-node-biopsy-to-treatment-of-locally-advanced-stages-of-cervical-cancers
#12
J Sláma, M Zikán, D Fischerová, R Kocián, A Germanová, F Frühauf, D Cibula
OBJECTIVE: Usage of sentinel lymph-node (SLN) concept in locally advanced cervical cancers might help to individualise management. According to SLN status could be patients refered to neoadjuvant chemotherapy (NAC) with subsequent surgery or to primary chemoradiation. The aim of our study was to evaluate sensitivity of SLN detection in locally advanced cervical cancers and to assess the impact of NAC on frequency of their metastatic involvement. DESIGN: Retrospective clinical study...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27882746/-technique-of-pelvic-and-paraaortic-lymphadenectomy
#13
J Sláma, R Kocián
OBJECTIVE: Overview of classification, anatomical conditions, methods and complications of pelvic and paraaortic lymph-node dissection. DESIGN: Review article. SETTING: Department of Obstetrics and Gynecology, General Faculty Hospital and 1st Medical Faculty, Charles University, Prague. MATERIALS AND METHODS: Lymphadenectomy is classified according to its extent into sentinel lymph-node biopsy, debulking, sampling and systematic procedure and according to approach into extraperitoneal or transperitoneal procedure...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27882235/intraoperative-molecular-analysis-of-sentinel-lymph-nodes-following-neoadjuvant-chemotherapy-in-patients-with-clinical-node-negative-breast-cancer-an-institutional-study
#14
David Parada, Karla B Peña, F Francesc Riu, A Esther Aguilar, Sebastian Cohan
Sentinel lymph node biopsy (SLNB) is an accurate, safe method for determining the axillary lymph node status. However, insufficient evidence exists to support the recommendation of SLNB in patients who have had neoadjuvant chemotherapy (NAC) to downsize tumours and allow for breast conservation surgery. The present study aimed to use molecular approaches to evaluate the feasibility and accuracy of SLNB in patients treated with NAC prior to SLN mapping and surgery. A total of 50 consecutive patients with operable invasive breast carcinomas who had received prior NAC were assessed using the one-step nucleic acid amplification (OSNA) method...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27878928/sentinel-lymph-node-biopsy-for-early-oral-cancers-westmead-hospital-experience
#15
Muzib Abdul-Razak, Hsiang Chung, Eva Wong, Carsten Palme, Michael Veness, David Farlow, Hedley Coleman, Gary Morgan
BACKGROUND: Sentinel lymph node biopsy (SLNB) has become an alternative option to elective neck dissection (END) for early oral cavity squamous cell carcinoma (OCSCC) outside of Australia. We sought to assess the technical feasibility of SLNB and validate its accuracy against that of END in an Australian setting. METHODS: We performed a prospective cohort study consisting of 30 consecutive patients with cT1-2 N0 OCSCC referred to the Head and Neck Cancer Service, Westmead Hospital, Sydney, between 2011 and 2014...
November 23, 2016: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/27874206/spitz-nevi-and-other-spitzoid-neoplasms-in-children-overview-of-incidence-data-and-diagnostic-criteria
#16
REVIEW
Emi Dika, Giulia Maria Ravaioli, Pier Alessandro Fanti, Iria Neri, Annalisa Patrizi
Spitz nevi are benign melanocytic neoplasms characterized by epithelioid or spindle melanocytes or both. In some rare cases their presentation overlaps with the clinical and histopathologic features of malignant melanoma, so a differential diagnosis can be difficult to make. Intermediate forms between Spitz nevi and malignant melanoma, with unpredictable behavior, have been called atypical Spitz tumors. A literature search was performed to review the clinical, dermoscopic, genetic, and histopathologic aspects of spitzoid tumors...
November 22, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27872527/role-of-axillary-ultrasound-fine-needle-aspiration-cytology-and-sentinel-lymph-node-biopsy-in-clinically-n0-breast-cancer
#17
Gaurav Goel, P D Janaki, N V Smitha, Rajanbabu Anupama, P Shanmugha Sundaram, Y S Nataraj, D K Vijaykumar
This study evaluates the combined role of axillary ultrasound, fine needle aspiration cytology and sentinel lymph node biopsy in clinically N0 axilla. Between January 2014 and June 2015, 150 women with early breast cancer underwent axillary ultrasound as a first investigation for nodal status. Suspicious nodes were subjected to image guided fine needle aspiration cytology. Non-suspicious and fine needle aspiration cytology negative axillary nodes proceeded to sentinel lymph node biopsy at time of primary breast surgery...
December 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27872522/sentinel-lymph-node-biopsy-in-n0-neck-for-squamous-cell-carcinoma-of-oral-cavity-a-prospective-study
#18
K Shivakumar, Goel Vipin, Manjunath Suraj, B V Rajaram, Ramesh Rakesh, A Anuradha, K Hemanth
Oral cancers in India are very common. SLNB (sentinel lymph node biopsy) for the management of the cN0 neck provides proper staging with less morbidity. The study aims at assessment of the technical feasibility and accuracy of SLNB. Two by two table and Kappa statistic was used to compare SLN and END. In 14 cases out of 16 cases, SLN was identified. Sensitivity and specificity of 100 % were found. One hundred percent agreement was observed between SLN and END using kappa statistics. A meta-analysis of 19 studies showed 97...
December 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27866291/japanese-contribution-to-the-field-of-sentinel-lymph-node-biopsy-for-breast-cancer-patients-introduction-to-invited-articles
#19
REVIEW
Shinzaburo Noguchi
No abstract text is available yet for this article.
November 19, 2016: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27864624/sentinel-lymph-node-biopsy-using-indocyanine-green-fluorescence-in-early-stage-breast-cancer-a-meta-analysis
#20
REVIEW
Tomoharu Sugie, Takafumi Ikeda, Atsushi Kawaguchi, Akira Shimizu, Masakazu Toi
Sentinel lymph node (SLN) biopsy using indocyanine green (ICG) fluorescence is safe and has a high detection rate for SLNs. However, the results of this novel technique are heterogeneous. The objective of this meta-analysis was to evaluate the diagnostic performance of the ICG fluorescence method compared with the standard radioisotope (RI) method. All eligible studies were identified from 2005 through 2015. A proportion meta-analysis was performed using a fixed effects and/or random effects model based on the study heterogeneity...
November 19, 2016: International Journal of Clinical Oncology
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