Masoud Siaghi, Ayoob Karimizade, Amir Mellati, Majid Saeedi, Fereshteh Talebpour Amiri, Shakiba Kalhori, Somayeh Shahani
In clinical practice, wound care has always been challenging. Hydrogels play a key role in facilitating active wound recovery by absorbing exudates, maintaining moisture, and alleviating pain through cooling. In this study, type I collagen was isolated from the skin of crucian carp (Carassius carassius) and verified by amino acid analysis, FTIR, and SDS-PAGE. By adopting a new approach, luteolin was added to collagen hydrogels in situ after being dissolved in an alkaline solution. XRD and SEM confirmed the luteolin was incorporated and entirely distributed throughout the hydrogel...
April 18, 2024: International Journal of Pharmaceutics