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https://www.readbyqxmd.com/read/29763648/autism-spectrum-disorder-classification-diagnosis-and-therapy
#1
REVIEW
Samata R Sharma, Xenia Gonda, Frank I Tarazi
Autism Spectrum Disorder (ASD) refers to a group of neurodevelopmental disorders including autism, Asperger's syndrome (AS) and pervasive developmental disorder-not otherwise specified (PDD-NOS). The new diagnostic criteria of ASD focuses on two core domains: social communication impairment and restricted interests/repetitive behaviors. The prevalence of ASD has been steadily increasing over the past two decades, with current estimates reaching up to 1 in 36 children. Hereditary factors, parental history of psychiatric disorders, pre-term births, and fetal exposure to psychotropic drugs or insecticides have all been linked to higher risk of ASD...
May 12, 2018: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29740504/epidural-abscess-presenting-as-severe-depression-with-suicidal-ideations-case-report
#2
Erin D'Agostino, Vyacheslav Makler, David F Bauer
Background: Epidural abscess (EDA) is an uncommon form of intracranial infection that generally presents with fever, headache, and focal neurologic deficit. Imaging generally reveals a lentiform collection with diffusion restriction on diffusion weighted image. We present an interesting case in which a patient with EDA presented with three weeks of depression with suicidal ideations. The patient displayed no notable infectious signs and the imaging was suggestive of chronic subdural hematoma (SDH) rather than EDA...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29732651/supporting-carers-of-children-and-adolescents-with-eating-disorders-in-austria-succeat-study-protocol-for-a-randomised-controlled-trial
#3
Claudia Franta, Julia Philipp, Karin Waldherr, Stefanie Truttmann, Elisabeth Merl, Gabriele Schöfbeck, Doris Koubek, Clarissa Laczkovics, Hartmut Imgart, Annika Zanko, Michael Zeiler, Janet Treasure, Andreas Karwautz, Gudrun Wagner
Supporting Carers of Children and Adolescents with Eating Disorders in Austria (SUCCEAT) is an intervention for carers of children and adolescents with anorexia nervosa and atypical anorexia nervosa. This paper describes the study protocol for a randomised controlled trial including the process and economic evaluation. Carers are randomly allocated to one of the 2 SUCCEAT intervention formats, either 8 weekly 2-hr workshop sessions (n = 48) or web-based modules (n = 48), and compared with a nonrandomised control group (n = 48)...
May 6, 2018: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/29701157/pharmacological-treatment-of-body-dysmorphic-disorder
#4
Kevin Hong, Vera Nezgovorova, Genoveva Uzunova, Danya Schlussel, Eric Hollander
Body dysmorphic disorder is a challenging disorder that manifests as erroneously perceived flaws in one's physical appearance and repetitive behaviors in response to appearance concerns. This disorder is also frequently comorbid with other psychiatric disorders, including major depressive disorder and autism spectrum disorder. It is currently understood to arise from a combination of biological, psychological, and environmental factors. Treatment of body dysmorphic disorder typically consists of a combination of pharmacotherapy and cognitive behavioral therapy...
April 26, 2018: Current Neuropharmacology
https://www.readbyqxmd.com/read/29694295/psychological-functioning-of-women-taking-illicit-drugs-during-pregnancy-and-the-growth-and-development-of-their-offspring-in-early-childhood
#5
Dana Serino, Bradley S Peterson, Tove S Rosen
OBJECTIVE: Assess psychosocial history and psychological functioning in women who use drugs during pregnancy and determine how drug exposure affects child development. METHODS: Pregnant marijuana (n = 38), cocaine (n = 35), methadone-maintained (n = 24), and control (n = 49) group women were enrolled and followed every 6 months through 18-24 months postnatally. RESULTS: There was a significantly higher incidence of mental illness in mothers in the drug groups...
April 25, 2018: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/29692740/language-patterns-discriminate-mild-depression-from-normal-sadness-and-euthymic-state
#6
Daria Smirnova, Paul Cumming, Elena Sloeva, Natalia Kuvshinova, Dmitry Romanov, Gennadii Nosachev
Objectives: Deviations from typical word use have been previously reported in clinical depression, but language patterns of mild depression (MD), as distinct from normal sadness (NS) and euthymic state, are unknown. In this study, we aimed to apply the linguistic approach as an additional diagnostic key for understanding clinical variability along the continuum of affective states. Methods: We studied 402 written reports from 124 Russian-speaking patients and 77 healthy controls (HC), including 35 cases of NS, using hand-coding procedures...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29678455/different-behavioral-and-pathological-changes-between-epilepsy-associated-depression-and-primary-depression-models
#7
Wei-Feng Peng, Fan Fan, Xin Li, Qian-Qian Zhang, Jing Ding, Xin Wang
PURPOSE: Comorbid depression is common in patients with epilepsy. However, the epilepsy-associated depression is generally atypical and has not been fully recognized by neurologists. This study aimed to compare the behavioral and pathological changes between the chronic lithium chloride-pilocarpine rat epilepsy model (Licl-pilocarpine model) and the Chronic Unpredictable Mild Stress rat depression model (CUMS model), to evaluate for differences between epilepsy-associated depression and primary depression...
April 17, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29670796/huntington-s-disease-in-a-patient-misdiagnosed-as-conversion-disorder
#8
João Machado Nogueira, Ana Margarida Franco, Susana Mendes, Anabela Valadas, Cristina Semedo, Gustavo Jesus
Huntington's disease (HD) is an inherited, progressive, and neurodegenerative neuropsychiatric disorder caused by the expansion of cytosine-adenine-guanine (CAG) trinucleotide in Interested Transcript (IT) 15 gene on chromosome 4. This pathology typically presents in individuals aged between 30 and 50 years and the age of onset is inversely correlated with the length of the CAG repeat expansion. It is characterized by chorea, cognitive deficits, and psychiatric symptoms. Usually the psychiatric disorders precede motor and cognitive impairment, Major Depressive Disorder and anxiety disorders being the most common presentations...
2018: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/29670407/first-episode-psychosis-as-the-initial-presentation-of-multiple-sclerosis-a-case-report
#9
Athena Enderami, Rose Fouladi, Seyed Hamzeh Hosseini
Background: Multiple sclerosis (MS) is an inflammatory disease that affects the central nervous system (CNS). MS with episode of psychosis is a rare entity, and to the best of our knowledge, no case has been reported from Iran till date. Case presentation: We report a case of MS with first-episode psychosis in a 27-year-old single man with no history of psychiatric disorder or drug abuse. The patient developed neurological symptoms after 3 months and was finally diagnosed as a case of MS...
2018: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29652308/-clinical-psychopathological-aspects-of-therapeutic-effects-of-agomelatine-valdoxan-and-its-place-in-perfection-of-methods-of-therapy-of-postschizophrenic-depressive-disorders
#10
G P Panteleyeva, L I Abramova, T E Novozhenova, N V Subbotskaya, D V Tikhonov, P E Yumatova, I Yu Nikiforova
AIM: To determine a therapeutic effect of agomelatine (valdoxan) on post-schizophrenic depression (PSD), taking into account its psychopathological structure. MATERIAL AND METHODS: A total of 33 patients of both sexes (average age was 32.1 yrs) with symptoms of post-schizophrenic depression (F20.4 according to ICD-10) were examined by using clinical and psychometric methods in the dynamics of shift-like schizophrenia. HAMD-17, PANSS and CGI-S scales were applied...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29643124/myocardial-ischemia-as-a-result-of-external-coronary-compression-from-infective-aortic-root-aneurysm-atypical-presentation-of-prosthetic-valve-endocarditis
#11
Baskar Sekar, Richard Wheeler, Navroz Masani, Sean Gallagher
This case describes an unusual presentation of prosthetic valve endocarditis: an acute coronary syndrome. A 67-year-old gentleman presented with cardiac sounding chest pain on a background of a short history of night sweats, weight loss and general malaise. Four months previously he had undergone bio-prosthetic aortic valve replacement for severe aortic stenosis and single vessel bypass grafting of the obtuse marginal. Whilst having chest pain his ECG showed infero-lateral ST depression. Early coronary angiography revealed a new right coronary artery lesion that was not present prior to his cardiac surgery...
April 11, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29628068/negative-autobiographical-memory-in-depression-reflects-elevated-amygdala-hippocampal-reactivity-and-hippocampally-associated-emotion-regulation
#12
Bruce P Doré, Odile Rodrik, Chelsea Boccagno, Alexa Hubbard, Jochen Weber, Barbara Stanley, Maria A Oquendo, Jeffrey M Miller, M Elizabeth Sublette, J John Mann, Kevin N Ochsner
BACKGROUND: Dysregulated autobiographical recall is observed in major depressive disorder (MDD). However, it is unknown whether people with MDD show abnormalities in memory-, emotion-, and control-related brain systems during reactivity to and regulation of negative autobiographical memories. METHODS: We used functional magnetic resonance imaging to identify neural mechanisms underlying MDD-related emotional responses to negative autobiographical memories and the ability to downregulate these responses using a cognitive regulatory strategy known as reappraisal...
April 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29622043/aripiprazole-induced-sleep-related-eating-disorder-a-case-report
#13
Nobuyuki Kobayashi, Masahiro Takano
BACKGROUND: Sleep-related eating disorder is characterized by parasomnia with recurrent episodes of nocturnal eating or drinking during the main sleep period. Several drugs, including atypical antipsychotics, induce sleep-related eating disorder. However, aripiprazole has not previously been associated with sleep-related eating disorder. CASE PRESENTATION: A 41-year-old Japanese man visited our clinic complaining of depression. The patient was treated with sertraline, which was titrated up to 100 mg for 4 weeks...
April 5, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29617396/the-impact-of-depression-and-antidepressant-usage-on-primary-biliary-cholangitis-clinical-outcomes
#14
Abdel-Aziz Shaheen, Gilaad G Kaplan, Wagdi Almishri, Isabelle Vallerand, Alexandra D Frolkis, Scott Patten, Mark G Swain
BACKGROUND: Depression is prevalent in primary biliary cholangitis (PBC) patients. Our aims were to examine the effects of depression and antidepressants on hepatic outcomes of PBC patients. METHODS: We used the UK Health Improvement Network database to identify PBC patients between 1974 and 2007. Our primary outcome was one of three clinical events: decompensated cirrhosis, liver transplantation and death. We assessed depression and each class of antidepressant medication in adjusted multivariate Cox proportional hazards models to identify independent predictors of outcomes...
2018: PloS One
https://www.readbyqxmd.com/read/29614992/a-research-study-review-of-effectiveness-of-treatments-for-psychiatric-conditions-common-to-end-stage-cancer-patients-needs-assessment-for-future-research-and-an-impassioned-plea
#15
Ralph J Johnson
BACKGROUND: Rates of psychiatric conditions common to end-stage cancer patients (delirium, depression, anxiety disorders) remain unchanged. However, patient numbers have increased as the population has aged; indeed, cancer is a chief cause of mortality and morbidity in older populations. Effectiveness of psychiatric interventions and research to evaluate, inform, and improve interventions is critical to these patients' care. This article's intent is to report results from a recent review study on the effectiveness of interventions for psychiatric conditions common to end-stage cancer patients; the review study assessed the state of research regarding treatment effectiveness...
April 3, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29613946/clinical-predictors-of-response-to-magnetic-seizure-therapy-in-depression-a-preliminary-report
#16
Sarah Kayser, Bettina H Bewernick, Stefanie Wagner, Thomas E Schlaepfer
OBJECTIVES: Magnetic seizure therapy (MST) is a novel convulsive brain stimulation method in clinical testing, which is used as an alternative for electroconvulsive therapy in patients with treatment-resistant depression (TRD). Preliminary studies have suggested that MST leads to fewer cognitive adverse effects than electroconvulsive therapy but has similar efficacy. However, the clinical predictors of response to MST have not been evaluated yet. This study aimed to investigate whether these predictors can be identified in patients with TRD...
April 2, 2018: Journal of ECT
https://www.readbyqxmd.com/read/29608076/body-image-and-self-esteem-in-disorders-of-sex-development-a-european-multicenter-study
#17
Tim C van de Grift, Peggy T Cohen-Kettenis, Annelou L C de Vries, Baudewijntje P C Kreukels
OBJECTIVE: Disorders/differences of sex development (DSD) refer to congenital conditions with atypical sex development and are associated with psychosexual issues. The aim of this study was to assess body image and self-esteem across the DSD spectrum and to study the impact of diagnosis and mediating characteristics. METHOD: Data collection was part of dsd-LIFE, a cross-sectional study conducted by 14 European expert clinics on wellbeing and health care evaluation of adults diagnosed with DSD...
April 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29604382/the-role-of-depressive-subtypes-within-the-neuroinflammation-hypothesis-of-major-depressive-disorder
#18
Marie Woelfer, Vanessa Kasties, Sascha Kahlfuss, Martin Walter
Major depressive disorder (MDD) is a very common disease that affects more than 350 million people worldwide, representing an enormous socioeconomic burden. From a clinical perspective, MDD can be divided into different subtypes, such as melancholic or atypical MDD. Interestingly, increasing evidence points towards an involvement of the immune system in MDD pathogenesis. However, inflammation does not seem to have the same impact on every MDD type. Here, we describe how inflammation can affect monoaminergic and glutamatergic neurotransmission, which provides a possible mechanism for MDD onset...
March 28, 2018: Neuroscience
https://www.readbyqxmd.com/read/29595710/cardiovascular-risk-factors-as-differential-predictors-of-incident-atypical-and-typical-major-depressive-disorder-in-u-s-adults
#19
Jay S Patel, Jessica Berntson, Brittanny M Polanka, Jesse C Stewart
OBJECTIVES: While the association between major depressive disorder (MDD) and future cardiovascular disease (CVD) is established, less is known about the relationship between CVD risk factors and future depression, and no studies have examined MDD subtypes. Our objective was to determine whether hypertension, tobacco use, and body mass index (BMI) differentially predict atypical and typical MDD in a national sample of U.S. adults. METHODS: We examined prospective data from 22,915 adults with no depressive disorder history at baseline who participated in Wave 1 (2001-2002) and Wave 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)...
March 28, 2018: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29594370/gender-difference-in-the-point-prevalence-symptoms-comorbidity-and-correlates-of-depression-findings-from-the-lagos-state-mental-health-survey-lsmhs-nigeria
#20
Abiodun O Adewuya, Olurotimi A Coker, Olayinka Atilola, Bolanle A Ola, Mathew P Zachariah, Tomilola Adewumi, Olufemi Olugbile, Adedolapo Fasawe, Olajide Idris
It is still unclear whether the gender difference in the rate of depression cuts across cultures or is specific to some depressive symptoms. This study evaluated the gender difference in current prevalence, symptoms, comorbidity, and correlates of depression in Lagos, Nigeria. A total of 11,246 adult participants (6525 females and 4712 males) in a face-to-face household survey were assessed for symptoms of depression. They were also assessed for symptoms of anxiety, somatic symptoms, alcohol and substance use disorders, and disability...
March 28, 2018: Archives of Women's Mental Health
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