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https://www.readbyqxmd.com/read/29333891/therapeutic-potential-of-zataria-multiflora-boiss-in-treatment-of-irritable-bowel-syndrome-ibs
#1
Mohaddese Mahboubi
Irritable Bowel syndrome (IBS), the most common chronic functional gastrointestinal disorder, is categorized as IBS-C and IBS-D, which are equivalent to Ghoolenj Rihi and Maghs Rihi in Iranian traditional medicine. One of the main applications of Zataria multiflora Boiss in traditional medicine is its efficacy in the gastrointestinal tract with symptoms such as IBS. The aim of this study was to evaluate the efficacy of Zataria multiflora essential oil in management of IBS. We used all the accessible references (electronic and published books, theses, and reports) to write this article...
January 15, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29332637/pilot-rct-of-an-integrative-group-therapy-for-patients-with-refractory-irritable-bowel-syndrome-isrctn02977330
#2
S Berens, E Stroe-Kunold, F Kraus, J Tesarz, A Gauss, B Niesler, W Herzog, R Schaefert
OBJECTIVE: Different forms of psychotherapeutic treatments have been proven effective in irritable bowel syndrome (IBS), but disorder-oriented and integrative concepts are still rare. Therefore, we implemented and evaluated an integrative group therapeutic concept within an interdisciplinary tertiary care clinic for functional gastrointestinal disorders (FGIDs). AIMS: present our integrative group concept, assess feasibility issues, and evaluate efficacy. METHODS: A pilot-RCT with a randomized controlled wait-listed group design was conducted...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29332625/positive-and-negative-affect-mediate-the-bidirectional-relationship-between-emotional-processing-and-symptom-severity-and-impact-in-irritable-bowel-syndrome
#3
Alice Sibelli, Trudie Chalder, Hazel Everitt, Joseph Chilcot, Rona Moss-Morris
INTRODUCTION: Individuals with IBS report higher levels of psychological distress compared to healthy controls. Distress has been associated with emotional processing difficulties but studies have not explored how the relationship between distress and emotional processing affects IBS. There is little research on the role of positive affect (PA) in IBS. AIMS: (a) If difficulties in self-reported emotional processing are associated with affect and IBS measures (i...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29329362/clostridium-butyricum-regulates-visceral-hypersensitivity-of-irritable-bowel-syndrome-by-inhibiting-colonic-mucous-low-grade-inflammation-through-its-action-on-nlrp6
#4
Kejia Zhao, Leimin Yu, Xi Wang, Yibo He, Bin Lu
Visceral hypersensitivity induced by stress is quite common in irritable bowel syndrome (IBS) patients. Probiotics play an important role in reducing visceral hypersensitivity in IBS patients. However, the mechanism has not been clearly elucidated. In this study, we investigated the role of nod-like receptor pyrin domain-containing protein 6 (NLRP6) in Clostridium butyricum-regulated IBS induced by stress. Our results showed that NLRP6 was down-regulated in IBS group colon tissues. In addition, IL-18, IL-1β, myeloperoxidase (MPO), d-lactic acid (D-LA), and CD172a were up-regulated in the IBS group of colonic mucous...
January 10, 2018: Acta Biochimica et Biophysica Sinica
https://www.readbyqxmd.com/read/29327820/gastroenterology-today-between-certainties-and-news-a-meeting-held-in-turin-on-may-27-2017
#5
Rinaldo Pellicano, Davide G Ribaldone, Marco Astegiano, Luca Dughera, Edda Battaglia, Anna Morgando, Arrigo Arrigoni, Mauro Spandre, Mario Grassini, Giorgio M Saracco, Francis Mégraud
This special article reports on two crucial issues discussed during a meeting. The first was the updated management of Helicobacter pylori infection. This was approached taking into account the recent European Guidelines, with a focus on novelties in treatment. In particular, considering the increasing H. pylori antibiotic resistance to clarithromycin, in countries with a high clarithromycin resistance rate the bismuth-containing quadruple therapies should be preferred. The new formulation, with bismuth, metronidazole, and tetracycline contained in a single capsule (three-in-one), has shown exciting results both in naive and in non-responder patients...
January 10, 2018: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/29327358/opioid-medication-use-in-patients-with-gastrointestinal-diagnoses-vs-unexplained-gastrointestinal-symptoms-in-the-us-veterans-health-administration
#6
G S Sayuk, N Kanuri, C P Gyawali, B M Gott, B D Nix, R A Rosenheck
BACKGROUND: While opioid prescriptions have increased alarmingly in the United States (US), their use for unexplained chronic gastrointestinal (GI) pain (eg, irritable bowel syndrome) carries an especially high risk for adverse effects and questionable benefit. AIM: To compare opioid use among US veterans with structural GI diagnoses (SGID) and those with unexplained GI symptoms or functional GI diagnoses (FGID), a group for whom opioids have no accepted role. METHODS: Veterans Health Administration (VHA) administrative data from fiscal year 2012 were used to identify veterans with diagnostic codes recorded for SGID and FGID...
January 12, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29325791/the-therapeutic-effects-of-cannabis-and-cannabinoids-an-update-from-the-national-academies-of-sciences-engineering-and-medicine-report
#7
REVIEW
Donald I Abrams
The National Academies of Sciences, Engineering and Medicine conducted a rapid turn-around comprehensive review of recent medical literature on The Health Effects of Cannabis and Cannabinoids. The 16-member committee adopted the key features of a systematic review process, conducting an extensive search of relevant databases and considered 10,000 recent abstracts to determine their relevance. Primacy was given to recently published systematic reviews and primary research that studied one of the committee's 11 prioritized health endpoints- therapeutic effects; cancer incidence; cardiometabolic risk; respiratory disease; immune function; injury and death; prenatal, perinatal and postnatal outcomes; psychosocial outcomes; mental health; problem Cannabis use; and Cannabis use and abuse of other substances...
January 8, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29319900/laypersons-knowledge-and-perceptions-of-irritable-bowel-syndrome-as-potential-barriers-to-care
#8
LeeAnne B Sherwin
AIMS: To describe the layperson's knowledge and perceptions regarding the aetiology, pathogenesis, prevalence, medical evaluation, diagnosis and treatment of Irritable Bowel Syndrome. BACKGROUND: Diagnosis acceptance and adherence to treatment is influenced by the views of the patient's social networks. Little is known how these networks influence those with Irritable Bowel Syndrome. DESIGN: Cross-sectional study of two-hundred four laypersons, ages 18-80 years without an Irritable Bowel Syndrome diagnosis...
January 10, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29319191/linaclotide-in-irritable-bowel-syndrome-with-constipation-a-phase-3-randomized-trial-in-china-and-other-regions
#9
Yunsheng Yang, Jingyuan Fang, Xiaozhong Guo, Ning Dai, Xizhong Shen, Youlin Yang, Jing Sun, Bal Raj Bhandari, David S Reasner, Jacquelyn A Cronin, Mark G Currie, Jeffrey M Johnston, Peter Zeng, Niwat Montreewasuwat, George Zhijian Chen, Sam Lim
BACKGROUND AND AIM: Linaclotide is a guanylate cyclase-C agonist approved in multiple countries to treat irritable bowel syndrome with constipation (IBS-C). China has unmet need for well-tolerated therapy that is effective in treating both bowel and abdominal symptoms of IBS-C. This trial evaluated linaclotide's efficacy and safety in IBS-C patients in China and other regions. METHODS: This Phase 3, double-blind trial randomized IBS-C patients to once-daily oral 290-μg linaclotide or placebo at centers in China, North America, and Oceania...
January 10, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29318645/endometriosis-increased-the-risk-of-bladder-pain-syndrome-interstitial-cystitis-a-population-based-study
#10
Chia-Chang Wu, Shiu-Dong Chung, Herng-Ching Lin
OBJECTIVE: Previous studies have suggested an association between bladder pain syndrome/interstitial cystitis (BPS/IC) and endometriosis. However, no nation-wide population study has yet reported an association between them. In this study, we examined the risk of BPS/IC among subjects with endometriosis during a 3-year follow-up in Taiwan using a population-based dataset. STUDY DESIGN: This study comprised 9191 subjects with endometriosis, and 27 573 subjects randomly selected as controls...
January 10, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29317064/comparison-of-geographic-distributions-of-irritable-bowel-syndrome-with-inflammatory-bowel-disease-fail-to-support-common-evolutionary-roots-irritable-bowel-syndrome-and-inflammatory-bowel-diseases-are-not-related-by-evolution
#11
Andrew Szilagyi, Xiaoqing Xue
Irritable Bowel Syndrome (IBS) shares overlapping symptoms and some features of pathogenesis with Inflammatory Bowel Diseases (IBD: Crohn's disease [CD], and Ulcerative Colitis [UC]). Geographic markers such as latitude/sunshine and more recently lactase population distributions are found to be correlated with IBD. As a result of clinical and pathogenic similarities between the 2 conditions, some authorities questioned whether a connection exists between them. We compare IBS directly with IBD, and indirectly with geographic markers associated with IBD, in order to evaluate possible evolutionary links between IBS and IBD...
January 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29315154/characteristics-and-comorbidities-of-inpatients-without-celiac-disease-on-a-gluten-free-diet
#12
John W Blackett, Meghana Shamsunder, Norelle R Reilly, Peter H R Green, Benjamin Lebwohl
OBJECTIVES: Despite the increasing popularity of gluten-free diet (GFD), the demographic characteristics and medical features of patients without celiac disease on this diet have not been extensively investigated.We aimed to characterize the medical conditions and demographic backgrounds of hospitalized patients without celiac disease who adhere to a GFD, to further understand their reasons for gluten avoidance. MATERIALS AND METHODS: We performed an observational cohort study on all inpatients at Columbia University Medical Center on a GFD in 2011-2016, excluding those with celiac disease, compared with age-matched and sex-matched inpatients on a regular diet...
January 8, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29314137/editorial-irritable-bowel-syndrome-in-addition-to-having-properly-trained-dietitians-is-it-time-to-add-a-yoga-teacher-to-our-multidisciplinary-team
#13
EDITORIAL
J G Muir, M Iacovou
No abstract text is available yet for this article.
February 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29314131/editorial-irritable-bowel-syndrome-in-addition-to-having-properly-trained-dietitians-is-it-time-to-add-a-yoga-teacher-to-our-multidisciplinary-team-authors-reply
#14
EDITORIAL
D Schumann, H Cramer
No abstract text is available yet for this article.
February 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29313694/right-colon-mucinous-adenocarcinoma-mimicking-a-hydatid-cyst
#15
Noelia Ibáñez, Juan Ángel Fernández, Álvaro Jesús Gómez, Pascual Parrilla
Hydatid disease is a fecal-oral transmission zoonosis which is endemically distributed among Mediterranean countries such as Morocco. It usually presents asymptomatically and a diagnosis is made due to cyst complications. It is most frequently located in the liver and lungs and forms large masses. The incidence of colon cancer has increased amongst population under 50 years of age during the last few decades. It has been proposed that young adult cases may have histological characteristics with a more aggressive clinical behavior...
January 9, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29310568/ramosetron-for-the-treatment-of-irritable-bowel-syndrome-with-diarrhea-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
Qingqing Qi, Yan Zhang, Feixue Chen, Xiuli Zuo, Yanqing Li
BACKGROUND: Ramosetron is a potent and selective serotonin type 3 receptor antagonist. This meta-analysis aimed to analyze the efficacy and safety of ramosetron for irritable bowel syndrome with diarrhea (IBS-D). METHODS: Pubmed, MEDLINE, EMBASE and the Cochrane Library were searched for randomized controlled trials investigating the efficacy and safety of ramosetron for IBS-D. Risk of bias was assessed as described in the Cochrane handbook. A random effects model was used to calculate the effects of ramosetron vs placebo on symptomatic improvements, including relief of overall IBS symptoms, relief of abdominal discomfort/pain, improvement in abnormal bowel habits, and improvement in stool consistency, expressed as pooled relative risks (RRs) with 95% confidence interval (CI)...
January 8, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29310143/-irritable-bowel-syndrome-disection-of-a-disease-a-13-steps-polemic
#17
Paul Enck, Thomas Frieling, Michael Schemann
No abstract text is available yet for this article.
November 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29309469/the-evidence-for-herbal-and-botanical-remedies-part-1
#18
Michael Malone, Gary Tsai
There is evidence to support the use of capsaicin to relieve osteoarthritis and postherpetic neuralgia and support for green tea to serve as a lipid-lowering agent and help treat diabetes. Similarly, researchers have found that peppermint may be of value in the management of irritable bowel syndrome. We also review the literature on butterbur for migraine headaches, but serious safety issues exist.
January 2018: Journal of Family Practice
https://www.readbyqxmd.com/read/29307992/fructo-oligosaccharide-intensifies-visceral-hypersensitivity-and-intestinal-inflammation-in-a-stress-induced-irritable-bowel-syndrome-mouse-model
#19
Bin-Rui Chen, Li-Jun Du, Hui-Qin He, John J Kim, Yan Zhao, Ya-Wen Zhang, Liang Luo, Ning Dai
AIM: To determine whether fructo-oligosaccharide (FOS) affects visceral sensitivity, inflammation, and production of intestinal short-chain fatty acids (SCFA) in an irritable bowel syndrome (IBS) mouse model. METHODS: Mice were randomly assigned to daily oral gavage of saline solution with or without FOS (8 g/kg body weight) for 14 d. Mice were further assigned to receive either daily one-hour water avoidance stress (WAS) or sham-WAS for the first 10 d. After 2 wk, visceral sensitivity was measured by abdominal withdrawal reflex in response to colorectal distension and mucosal inflammation was evaluated...
December 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29306954/management-of-functional-somatic-syndromes-and-bodily-distress
#20
Peter Henningsen, Stephan Zipfel, Heribert Sattel, Francis Creed
Functional somatic syndromes (FSS), like irritable bowel syndrome or fibromyalgia and other symptoms reflecting bodily distress, are common in practically all areas of medicine worldwide. Diagnostic and therapeutic approaches to these symptoms and syndromes vary substantially across and within medical specialties from biomedicine to psychiatry. Patients may become frustrated with the lack of effective treatment, doctors may experience these disorders as difficult to treat, and this type of health problem forms an important component of the global burden of disease...
January 6, 2018: Psychotherapy and Psychosomatics
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