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https://www.readbyqxmd.com/read/29468679/remote-treatment-of-sleep-related-trichotillomania-and-trichophagia
#1
Katherine R Lichtblau, Patrick W Romani, Brian D Greer, Wayne W Fisher, Allie K Bragdon
We used a biobehavioral treatment consisting of melatonin and a standardized bed and wake time to decrease one girl's head and mouth touches associated with sleep-related trichotillomania and trichophagia. We remotely coached the girl's caregiver to implement all procedures and monitored response to treatment using a DropCam Pro video camera equipped with night-vision capabilities. Head and mouth touches decreased, and her sleep pattern improved with the combination of treatment strategies. We discuss our use of a novel mode of service delivery to treat sleep-related problem behavior...
February 21, 2018: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/29425391/incidence-and-outcomes-of-optical-zone-enlargement-and-recentration-after-previous-myopic-lasik-by-topography-guided-custom-ablation
#2
Dan Z Reinstein, Timothy J Archer, Glenn I Carp, Alastair J Stuart, Elizabeth L Rowe, Andrew Nesbit, Tara Moore
PURPOSE: To report the incidence, visual and refractive outcomes, optical zone enlargement, and recentration using topography-guided CRS-Master TOSCA II software with the MEL 80 excimer laser (Carl Zeiss Meditec AG, Jena, Germany) after primary myopic laser refractive surgery. METHODS: Retrospective analysis of 73 eyes (40 patients) with complaints of night vision disturbances due to either a decentration or small optical zone following a primary myopic laser refractive surgery procedure using the MEL 80 laser...
February 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29410641/rapid-adaptation-of-night-vision
#3
Adam Reeves, Rebecca Grayhem, Alex D Hwang
Apart from the well-known loss of color vision and of foveal acuity that characterizes human rod-mediated vision, it has also been thought that night vision is very slow (taking up to 40 min) to adapt to changes in light levels. Even cone-mediated, daylight, vision has been thought to take 2 min to recover from light adaptation. Here, we show that most, though not all adaptation is rapid, taking less than 0.6 s. Thus, monochrome (black-white-gray) images can be presented at mesopic light levels and be visible within a few 10th of a second, even if the overall light level, or level of glare (as with passing headlamps while driving), changes abruptly...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29353330/leveraging-variable-sensor-spatial-acuity-with-a-homogeneous-multi-scale-place-recognition-framework
#4
Adam Jacobson, Zetao Chen, Michael Milford
Most robot navigation systems perform place recognition using a single-sensor modality and one, or at most two heterogeneous map scales. In contrast, mammals perform navigation by combining sensing from a wide variety of modalities including vision, auditory, olfactory and tactile senses with a multi-scale, homogeneous neural map of the environment. In this paper, we develop a multi-scale, multi-sensor system for mapping and place recognition that combines spatial localization hypotheses at different spatial scales from multiple different sensors to calculate an overall place recognition estimate...
January 20, 2018: Biological Cybernetics
https://www.readbyqxmd.com/read/29326851/recent-advancements-in-gene-therapy-for-hereditary-retinal-dystrophies
#5
REVIEW
Ayşe Öner
Hereditary retinal dystrophies (HRDs) are degenerative diseases of the retina which have marked clinical and genetic heterogeneity. Common presentations among these disorders include night or colour blindness, tunnel vision, and subsequent progression to complete blindness. The known causative disease genes have a variety of developmental and functional roles, with mutations in more than 120 genes shown to be responsible for the phenotypes. In addition, mutations within the same gene have been shown to cause different disease phenotypes, even amongst affected individuals within the same family, highlighting further levels of complexity...
December 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29311648/auditory-opportunity-and-visual-constraint-enabled-the-evolution-of-echolocation-in-bats
#6
Jeneni Thiagavel, Clément Cechetto, Sharlene E Santana, Lasse Jakobsen, Eric J Warrant, John M Ratcliffe
Substantial evidence now supports the hypothesis that the common ancestor of bats was nocturnal and capable of both powered flight and laryngeal echolocation. This scenario entails a parallel sensory and biomechanical transition from a nonvolant, vision-reliant mammal to one capable of sonar and flight. Here we consider anatomical constraints and opportunities that led to a sonar rather than vision-based solution. We show that bats' common ancestor had eyes too small to allow for successful aerial hawking of flying insects at night, but an auditory brain design sufficient to afford echolocation...
January 8, 2018: Nature Communications
https://www.readbyqxmd.com/read/29259539/the-contribution-of-l-type-cav1-3-channels-to-retinal-light-responses
#7
Liheng Shi, Janet Ya-An Chang, Fei Yu, Michael L Ko, Gladys Y-P Ko
L-type voltage-gated calcium channels (LTCCs) regulate tonic neurotransmitter release from sensory neurons including retinal photoreceptors. There are three types of LTCCs (Cav1.2, Cav1.3, and Cav1.4) expressed in the retina. While Cav1.2 is expressed in all retinal cells including the Müller glia and neurons, Cav1.3 and Cav1.4 are expressed in the retinal neurons with Cav1.4 exclusively expressed in the photoreceptor synaptic terminals. Mutations in the gene encoding Cav1.4 cause incomplete X-linked congenital stationary night blindness in humans...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29240745/waking-up-to-poor-vision-after-a-night-out
#8
Nishanthan Ramachandran, Riyaz Bhikoo, John Ah-Chan, Harry Bradshaw
No abstract text is available yet for this article.
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29233238/neck-kinematics-and-electromyography-while-wearing-head-supported-mass-during-running
#9
Matthew M Hanks, JoEllen M Sefton, Gretchen D Oliver
BACKGROUND: Advanced combat helmets (ACH) coupled with night-vision goggles (NVG) are required for tactical athletes during training and service. Head and neck injuries due to head supported mass (HSM) are a common occurrence in military personnel. The current study aimed to investigate the effects of HSM on neck muscle fatigue that may lead to chronic stress and injury of the head and neck. METHODS: Subjects wore an ACH and were affixed with electromagnetic sensors to obtain kinematic data, as well as EMG electrodes to obtain muscle activations of bilateral sternocleidomastoid, upper trapezius, and paraspinal muscles while running on a treadmill...
January 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29223231/pupil-influence-on-the-quality-of-vision-in-rotationally-asymmetric-multifocal-iols-with-surface-embedded-near-segment
#10
Eric E Pazo, Richard N McNeely, Olivier Richoz, M Andrew Nesbit, Tara C B Moore, Jonathan E Moore
PURPOSE: To evaluate the influences of preoperative pupil parameters on the visual outcomes of the SBL-3, a rotationally asymmetric multifocal intraocular lens (IOL) with a surface-embedded near segment. SETTING: Cathedral Eye Clinic, Belfast, Northern Ireland, United Kingdom. DESIGN: Retrospective comparative case series. METHODS: Postoperatively, patients divided into 4 groups according to their pupil size as follows: Group A: 2...
November 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29210828/predicting-short-term-subjective-vision-performance-of-contact-lenses-used-in-myopia-control
#11
Jennie Diec, Daniel Tilia, Varghese Thomas, Ravi C Bakaraju
OBJECTIVE: To investigate whether initial assessment of contact lenses prescribed for myopia control (MC) predicts short-term visual performance. METHOD: Retrospective analysis of 43 participants in a double-masked, randomized, cross-over trial wearing at least one lens: single-vision (SV) lens (1-DAY ACUVUE MOIST) or MC lenses (MiSight or Proclear Multifocal-Distance +2.00D). Participants completed questionnaires at the fitting visit, a take-home questionnaire (THQ) 3 days after fitting and finally at the assessment visit (≥5 days after fitting)...
November 28, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29193673/ophthalmic-features-of-cone-rod-dystrophy-caused-by-pathogenic-variants-in-the-alms1-gene
#12
Fadi Nasser, Nicole Weisschuh, Pietro Maffei, Gabriella Milan, Corina Heller, Eberhart Zrenner, Susanne Kohl, Laura Kuehlewein
PURPOSE: We aim to describe ophthalmic characteristics and systemic findings in a cohort of seven patients with cone-rod retinal dystrophy (CORD) caused by pathogenic variants in the ALMS1 gene. METHODS: Seven patients with Alström syndrome (ALMS) were included in the study. A comprehensive ophthalmological examination was performed, including best-corrected visual acuity (BCVA), a semiautomated kinetic visual field exam, colour vision testing, full-field electroretinography testing according to International Society for Clinical Electrophysiology of Vision (ISCEV) standards, spectral domain optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) imaging, and slit lamp and dilated fundus examination...
November 30, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29192330/the-role-of-ocelli-in-cockroach-optomotor-performance
#13
Anna Honkanen, Paulus Saari, Jouni Takalo, Kyösti Heimonen, Matti Weckström
Insect ocelli are relatively simple eyes that have been assigned various functions not related to pictorial vision. In some species they function as sensors of ambient light intensity, from which information is relayed to various parts of the nervous system, e.g., for the control of circadian rhythms. In this work we have investigated the possibility that the ocellar light stimulation changes the properties of the optomotor performance of the cockroach Periplaneta americana. We used a virtual reality environment where a panoramic moving image is presented to the cockroach while its movements are recorded with a trackball...
November 30, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/29188504/design-and-development-of-aav-based-gene-supplementation-therapies-for-achromatopsia-and-retinitis-pigmentosa
#14
Christian Schön, Elvir Becirovic, Martin Biel, Stylianos Michalakis
Achromatopsia (ACHM) and retinitis pigmentosa (RP) are inherited disorders caused by mutations in cone and rod photoreceptor-specific genes, respectively. ACHM strongly impairs daylight vision, whereas RP initially affects night vision and daylight vision at later stages. Currently, gene supplementation therapies utilizing recombinant adeno-associated virus (rAAV) vectors are being developed for various forms of ACHM and RP. In this chapter, we describe the procedure of designing and developing specific and efficient rAAV vectors for cone- and rod-specific gene supplementation...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29179637/cone-dystrophy-and-ectopic-synaptogenesis-in-a-cacna1f-loss-of-function-model-of-congenital-stationary-night-blindness-csnb2a
#15
D M Waldner, N C Giraldo Sierra, S Bonfield, L Nguyen, I S Dimopoulos, Y Sauvé, W K Stell, N T Bech-Hansen
Congenital stationary night blindness 2A (CSNB2A) is an X-linked retinal disorder, characterized by phenotypically variable signs and symptoms of impaired vision. CSNB2A is due to mutations in CACNA1F, which codes for the pore-forming α1F subunit of a L-type voltage-gated calcium channel, Cav1.4. Mouse models of CSNB2A, used for characterizing the effects of various Cacna1f mutations, have revealed greater severity of defects than in human CSNB2A. Specifically, Cacna1f-knockout mice show an apparent lack of visual function, gradual retinal degeneration, and disruption of photoreceptor synaptic terminals...
November 28, 2017: Channels
https://www.readbyqxmd.com/read/29179439/next-generation-sequencing-identified-novel-heterozygous-nonsense-mutation-in-cngb1-gene-associated-with-retinitis-pigmentosa-in-a-chinese-patient
#16
Santasree Banerjee, Junping Yao, Xinxin Zhang, Jianjun Niu, Zhongshan Chen
Retinitis pigmentosa (RP) is a severe hereditary eye disease characterized by progressive degeneration of photoreceptors and subsequent loss of vision. Retinitis pigmentosa (RP) is a clinically and genetically heterogeneous group of retinal diseases. Germline mutations of CNGB1 is associated with retinitis pigmentosa. We have identified and investigated a 34-year-old Chinese man with markedly have night vision blindness and loss of midperipheral visual field. The proband also lose his far peripheral visual field and also central vision...
October 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/29172937/panretinal-photocoagulation-a-review-of-complications
#17
Shivani V Reddy, Deeba Husain
Panretinal photocoagulation (PRP) is a mainstay of therapy for retinal ischemic disease. The procedure involves creating thermal burns in the peripheral retina leading to tissue coagulation, the overall consequence of which is improved retinal oxygenation. While highly effective, there have been concerns historically regarding the anatomic effects and visual complications following PRP, the most common of which include choroidal effusions, exudative retinal detachments, macular edema, visual field deficits, and night vision defects...
November 27, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29153322/bats-use-path-integration-rather-than-acoustic-flow-to-assess-flight-distance-along-flyways
#18
Gal Aharon, Meshi Sadot, Yossi Yovel
Navigation can be achieved using different strategies from simple beaconing to complex map-based movement [1-4]. Bats display remarkable navigation capabilities, ranging from nightly commutes of several kilometers and up to seasonal migrations over thousands of kilometers [5]. Many bats have been suggested to fly along fixed routes termed "flyways," when flying from their roost to their foraging sites [6]. Flyways commonly stretch along linear landscape elements such as tree lines, hedges, or rivers [7]. When flying along a flyway, bats must estimate the distance they have traveled in order to determine when to turn...
November 9, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29135076/a-heterozygous-mutation-in-rpgr-associated-with-x-linked-retinitis-pigmentosa-in-a-patient-with-turner-syndrome-mosaicism-45-x-46-xx
#19
Qi Zhou, Fengxia Yao, Feng Wang, Hui Li, Rui Chen, Ruifang Sui
Turner syndrome with retinitis pigmentosa (RP) is rare, with only three cases reported based on clinical examination alone. We summarized the 4-year follow-up and molecular findings in a 28-year-old patient with Turner syndrome and the typical features of short stature and neck webbing, who also had X-linked RP. Her main complaints were night blindness and progressive loss of vision since the age of 9 years. Ophthalmologic examination, optical coherent tomographic imaging, and visual electrophysiology tests showed classic manifestations of RP...
November 14, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29116965/mechanical-properties-of-contact-lens-materials
#20
Eon Kim, Mou Saha, Klaus Ehrmann
OBJECTIVES: To evaluate the mechanical properties of commonly available soft contact lens materials and compare results using custom-built MicroTensometer. METHODS: The Young modulus, parameters for stress relaxation, and toughness of 18 types of single vision soft contact lenses were measured using custom-built MicroTensometer. Five lenses of each type were soaked in standard phosphate buffered saline and measured at a temperature of 35°C. Each lens was flattened and sliced into a rectangular strip sample using two parallel blades...
November 7, 2017: Eye & Contact Lens
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