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https://www.readbyqxmd.com/read/27906097/a-10-year-old-child-presenting-with-syndromic-paucity-of-bile-ducts-alagille-syndrome-a-case-report
#1
Girish Kumar Pati, Ayaskanta Singh, Preetam Nath, Jimmy Narayan, Pradeep Kumar Padhi, Prasanta Kumar Parida, Kaumudee Pattnaik, Chittaranjan Panda, Shivaram Prasad Singh
BACKGROUND: Alagille syndrome, a rare genetic disorder with autosomal dominant transmission, manifests with five major features: paucity of interlobular bile ducts, characteristic facies, posterior embryotoxon, vertebral defects, and peripheral pulmonary stenosis. Globally, only 500 cases have so far been reported, with only five cases reported in the Indian subcontinent. Rarely, Alagille syndrome also presents with skin manifestations and early-onset chronic liver disease, which was found in our case...
November 30, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27905344/concurrent-retinitis-pigmentosa-and-pigmented-paravenous-retinochoroidal-atrophy-phenotypes-in-the-same-patient
#2
Dhanashree Ratra, Dhileesh P Chandrasekharan, P Aruldas, Vineet Ratra
We report a unique case of a patient with retinitis pigmentosa (RP) phenotype in one eye and pigmented paravenous retinochoroidal atrophy (PPRCA) phenotype in the other eye. We describe in detail the symptoms, clinical findings, and investigations done for a 32-year-old Indian woman. This patient had phenotypical picture resembling typical RP in the right eye, with characteristic symptoms of night blindness and constricted field of vision and a nonrecordable electroretinogram (ERG). The left eye of the same patient revealed typical PPRCA phenotype, with no night blindness, normal field, and normal ERG...
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27868168/use-perceptions-and-benefits-of-automotive-technologies-among-aging-drivers
#3
REVIEW
David W Eby, Lisa J Molnar, Liang Zhang, Renée M St Louis, Nicole Zanier, Lidia P Kostyniuk, Sergiu Stanciu
Advanced in-vehicle technologies have been proposed as a potential way to keep older adults driving for as long as they can safely do so, by taking into account the common declines in functional abilities experienced by older adults. The purpose of this report was to synthesize the knowledge about older drivers and advanced in-vehicle technologies, focusing on three areas: use (how older drivers use these technologies), perception (what they think about the technologies), and outcomes (the safety and/or comfort benefits of the technologies)...
December 2016: Injury Epidemiology
https://www.readbyqxmd.com/read/27845062/myopic-defocus-in-the-evening-is-more-effective-at-inhibiting-eye-growth-than-defocus-in-the-morning-effects-on-rhythms-in-axial-length-and-choroid-thickness-in-chicks
#4
Debora L Nickla, Pearl Thai, Rinita Zanzerkia Trahan, Kristen Totonelly
Animal models have shown that myopic defocus is a potent inhibitor of ocular growth: brief (1-2 h) daily periods of defocus are sufficient to counter the effects of much longer periods of hyperopic defocus, or emmetropic vision. While the variables of duration and frequency have been well-documented with regard to effect, we ask whether the efficacy of the exposures might also depend on the time of day that they are given. We also ask whether there are differential effects on the rhythms in axial length or choroidal thickness...
November 11, 2016: Experimental Eye Research
https://www.readbyqxmd.com/read/27828202/night-vision-integrated-performance-model-impact-of-a-recent-change-on-the-model-s-predictive-accuracy
#5
Richard Vollmerhausen
The U. S. Army has adopted the targeting task performance (TTP) image quality metric for formal analyses of electro-optical imager performance. The most recent release of the model, NVIPM, changes the way TTP is calculated in order to improve the accuracy of facial identification. Predictions of the original and modified models are compared to both laboratory and field data. The change degrades NVIPM predictive accuracy for the tactical vehicle target set which is often used in hardware procurement specifications...
October 17, 2016: Optics Express
https://www.readbyqxmd.com/read/27820927/south-american-weakly-electric-fish-gymnotiformes-are-long-wavelength-sensitive-cone-monochromats
#6
Da-Wei Liu, Ying Lu, Hong Young Yan, Harold H Zakon
Losses of cone opsin genes are noted in animals that are nocturnal or rely on senses other than vision. We investigated the cone opsin repertoire of night-active South American weakly electric fish. We obtained opsin gene sequences from genomic DNA of 3 gymnotiforms (Eigenmannia virescens, Sternopygus macrurus, Apteronotus albifrons) and the assembled genome of the electric eel (Electrophorus electricus). We identified genes for long-wavelength-sensitive (LWS) and medium-wavelength-sensitive cone opsins (RH2) and rod opsins (RH1)...
November 8, 2016: Brain, Behavior and Evolution
https://www.readbyqxmd.com/read/27810175/altered-sleep-wake-patterns-in-blindness-a-combined-actigraphy-and-psychometric-study
#7
S Aubin, C Gacon, P Jennum, M Ptito, R Kupers
OBJECTIVE: Light plays an important role in the synchronization of the internal biological clock and the environmental day/night pattern. Thus, absence of vision is often associated with both increases in reported sleep disturbances and incidence of free-running circadian rhythms. In this study we discuss variability in the sleep-wake pattern between blind and normal-sighted individuals. METHODS: Thirty-day actigraphy recordings were collected from 11 blind individuals without residual light perception and 11 age- and sex-matched normal-sighted controls...
August 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27800277/objective-determination-of-retinal-function-in-bietti-crystalline-retinopathy
#8
Dorukcan Akıncıoğlu, Ümit Yolcu, Abdullah İlhan, Fatih Çakır Gündoğan
A 44-year-old female patient without any known systemic or ocular disease presented with progressive visual loss and night vision disturbance. Visual acuity was 0.6 in the right eye and 0.2 in the left eye. Tiny, yellow crystalline deposits were seen on fundus examination. In addition, areas of retinal pigment epithelium and choriocapillaris atrophy were detected. Rod and cone responses were depressed in full-field flash electroretinogram. Multifocal electroretinogram testing showed severe foveal function disturbance with less severe but still depressed responses toward the periphery...
June 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27796129/-diagnosis-and-treatment-of-polycythaemia-vera-state-of-the-art
#9
Imelda Marton, Zsófia Simon, Zita Borbényi
Polycythaemia vera (PV), a condition characterized by blood hyperviscosity due to the expansion of the erythrocyte mass is the most common entity among all Philadelphia chromosome-negative myeloproliferative neoplasms. Arterial and venous thrombotic events are leading determinants of morbidity and mortality but impairment of quality of life due to vasomotor symptoms (erythromelalgia, pruritus) and disease-associated symptoms (tiredness, fatigue, pruritus, night sweats, vision problems, headache, concentration loss, abdominal discomfort, early satiety, fever, weight loss) are also present...
October 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27779951/neck-muscle-strain-in-air-force-pilots-wearing-night-vision-goggles
#10
Magnus Wallquist Pousette, Riccardo Lo Martire, Jan Linder, Mats Kristoffersson, Björn O Äng
INTRODUCTION: Flight-induced neck pain is common in high performance jet pilots, with incidents frequently attributed to high Gz flight maneuvers. The additional load of helmet-mounted night vision goggles (NVG) is believed to increase the risk, possibly from neck muscle strain in counteracting muscles. Hence, the aim was to investigate the effect of NVG on neck muscle strain as well as on the activity level distribution through a simulated flight session in air force pilots. METHODS: In this post hoc randomized crossover trial, four senior air force pilots each completed two identical 1...
2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27732723/homozygosity-for-a-recessive-loss-of-function-mutation-of-the-nrl-gene-is-associated-with-a-variant-of-enhanced-s-cone-syndrome
#11
Hadas Newman, Sergiu C Blumen, Itzhak Braverman, Rana Hanna, Beatrice Tiosano, Ido Perlman, Tamar Ben-Yosef
Purpose: To investigate the genetic basis for severe visual complaints by Bukharan Jewish patients with oculopharyngeal muscular dystrophy (OPMD). Methods: Polymerase chain reaction amplification and direct sequencing were used to test for NRL, PABPN1, and NR2E3 mutations. Complete ophthalmic examination included best-corrected visual acuity, biomicroscopic examination, optical coherence tomography, and fundus autofluorescence. Detailed electroretinography (ERG) testing was conducted including expanded International Society for Clinical Electrophysiology of Vision protocol for light-adapted and dark-adapted conditions, measurements of S-cone function, and ON-OFF light-adapted ERG...
October 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27677240/near-infrared-roll-off-free-electroluminescence-from-highly-stable-diketopyrrolopyrrole-light-emitting-diodes
#12
Mauro Sassi, Nunzio Buccheri, Myles Rooney, Chiara Botta, Francesco Bruni, Umberto Giovanella, Sergio Brovelli, Luca Beverina
Organic light emitting diodes (OLEDs) operating in the near-infrared spectral region are gaining growing relevance for emerging photonic technologies, such as lab-on-chip platforms for medical diagnostics, flexible self-medicated pads for photodynamic therapy, night vision and plastic-based telecommunications. The achievement of efficient near-infrared electroluminescence from solution-processed OLEDs is, however, an open challenge due to the low photoluminescence efficiency of most narrow-energy-gap organic emitters...
September 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27645106/retinal-transcriptome-sequencing-sheds-light-on-the-adaptation-to-nocturnal-and-diurnal-lifestyles-in-raptors
#13
Yonghua Wu, Elizabeth A Hadly, Wenjia Teng, Yuyang Hao, Wei Liang, Yu Liu, Haitao Wang
Owls (Strigiformes) represent a fascinating group of birds that are the ecological night-time counterparts to diurnal raptors (Accipitriformes). The nocturnality of owls, unusual within birds, has favored an exceptional visual system that is highly tuned for hunting at night, yet the molecular basis for this adaptation is lacking. Here, using a comparative evolutionary analysis of 120 vision genes obtained by retinal transcriptome sequencing, we found strong positive selection for low-light vision genes in owls, which contributes to their remarkable nocturnal vision...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27642541/bioptic-telescope-use-and-driving-patterns-of-drivers-with-age-related-macular-degeneration
#14
Alex R Bowers, Sarah S Sheldon, Dawn K DeCarlo, Eli Peli
PURPOSE: To investigate the telescope use and driving patterns of bioptic drivers with age-related macular degeneration (AMD). METHODS: A questionnaire addressing telescope use and driving patterns was administered by telephone interview to three groups of bioptic drivers: AMD (n = 31; median 76 years); non-AMD first licensed with a bioptic (n = 38; 53 years); and non-AMD first licensed without a bioptic (n = 47; 37 years). Driving patterns of bioptic AMD drivers were also compared with those of normal vision (NV) drivers (n = 36; 74 years) and nonbioptic AMD drivers (n = 34; 79 years)...
September 2016: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/27626467/ingaas-nanomembrane-si-van-der-waals-heterojunction-photodiodes-with-broadband-and-high-photoresponsivity
#15
Doo-Seung Um, Youngsu Lee, Seongdong Lim, Jonghwa Park, Wen-Chun Yen, Yu-Lun Chueh, Hyung-Jun Kim, Hyunhyub Ko
Development of broadband photodetectors is of great importance for applications in high-capacity optical communication, night vision, and biomedical imaging systems. While heterostructured photodetectors can expand light detection range, fabrication of heterostructures via epitaxial growth or wafer bonding still faces significant challenges because of problems such as lattice and thermal mismatches. Here, a transfer printing technique is used for the heterogeneous integration of InGaAs nanomembranes on silicon semiconductors and thus the formation of van der Waals heterojunction photodiodes, which can enhance the spectral response and photoresponsivity of Si photodiodes...
October 5, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27601873/psychophysical-measures-of-visual-function-and-everyday-perceptual-experience-in-a-case-of-congenital-stationary-night-blindness
#16
Jocelyn Cammack, John Whight, Vinette Cross, Andrew T Rider, Andrew R Webster, Andrew Stockman
An appreciation of the relation between laboratory measures of visual deficit and everyday perceptual experience is fundamental to understanding the impact of a visual condition on patients and so to a fuller characterization of the disorder. This study aims to understand better the interpretative processes by which modified sensory information is perceived by a patient with congenital stationary night blindness and the adaptive strategies that are devised to deal with their measurable visual loss. Psychophysical measurements of temporal resolution, spectral sensitivity, and color discrimination were conducted on a 78-year-old male patient with the condition, who was also interviewed at length about the ways in which his diagnosis affected his daily life...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27601870/clinical-presentation-and-visual-status-of-retinitis-pigmentosa-patients-a-multicenter-study-in-southwestern-nigeria
#17
Oluwatoyin Helen Onakpoya, Caroline Olufunlayo Adeoti, Tunji Sunday Oluleye, Iyiade Adeseye Ajayi, Timothy Majengbasan, Olayemi Kolawole Olorundare
BACKGROUND: To review the visual status and clinical presentation of patients with retinitis pigmentosa (RP). METHODOLOGY: Multicenter, retrospective, and analytical review was conducted of the visual status and clinical characteristics of patients with RP at first presentation from January 2007 to December 2011. Main outcome measure was the World Health Organization's visual status classification in relation to sex and age at presentation. Data analysis by SPSS (version 15) and statistical significance was assumed at P<0...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27573399/the-rise-of-near-infrared-emitters-organic-dyes-porphyrinoids-and-transition-metal-complexes
#18
REVIEW
Andrea Barbieri, Elisa Bandini, Filippo Monti, Vakayil K Praveen, Nicola Armaroli
In recent years, the interest in near-infrared (NIR) emitting molecules and materials has increased significantly, thanks to the expansion of the potential technological applications of NIR luminescence in several areas such as bioimaging, sensors, telecommunications, and night-vision displays. This progress has been facilitated by the development of new synthetic routes for the targeted functionalization and expansion of established molecular frameworks and by the availability of simpler and cheaper NIR detectors...
August 2016: Topics in Current Chemistry (Journal)
https://www.readbyqxmd.com/read/27563460/visual-performance-after-bilateral-implantation-of-a-four-haptic-diffractive-toric-multifocal-intraocular-lens-in-high-myopes
#19
John S M Chang, Vincent K C Chan, Jack C M Ng, Antony K P Law
Background. The vision with diffractive toric multifocal intraocular lenses after cataract surgery in long eyes has not been studied previously. Objectives. To report visual performance after bilateral implantation of a diffractive toric multifocal intraocular lens in high myopes. Methods. Prospective, observational case series to include patients with axial length of ≥26 mm and corneal astigmatism of >1 dioptre who underwent bilateral AT LISA 909M implantation. Postoperative examinations included photopic and mesopic distance, intermediate, and near visual acuity; photopic contrast sensitivity; visual symptoms (0-5); satisfaction (1-5); and spectacle independence rate...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27549579/recurrence-rate-and-subjective-symptoms-after-standardized-hamburg-protocol-phototherapeutic-keratectomy-on-recurrent-corneal-erosions
#20
J Mehlan, J Steinberg, L Traber, T Katz, S J Linke
PURPOSE: To evaluate the objective and subjective outcome after phototherapeutic keratectomy (PTK) on recurrent corneal erosions (Hamburg protocol). METHODS: For the standardized PTK according to Hamburg protocol a manual abrasio corneae performed with 20 % alcohol is followed by an excimer ablation depth of ≥15 μm (group1 15 μm; group 2 > 15 μm ablation depth) and 7 mm optical zone. All patients (N = 48) were invited for follow-up examinations and the evaluation of changes concerning subjective symptoms...
October 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
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