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Motion sickness

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https://www.readbyqxmd.com/read/28538515/effect-of-exposure-to-short-wavelength-light-on-susceptibility-to-motion-sickness
#1
Kyungshil Kim, Kazumi Hirayama, Kazuki Yoshida, Rika Yano, Masayuki Abe, Mika Otsuki, Satoshi Sakuraba, Shinya Sakai
This randomized cross-over study tested the hypothesis that exposure to short-wavelength light induces symptoms of motion sickness (MS). The study participants were 28 healthy adults (14 women; mean age±SD, 25.96±3.11 years). Two stimuli oscillating within a range of 0.4-0.6 Hz were used to induce MS: a blue wave stimulus with short-wavelength light (460 nm) and a green wave stimulus with middle-wavelength light (555 nm). All participants were exposed to both stimuli throughout two separate periods...
May 19, 2017: Neuroreport
https://www.readbyqxmd.com/read/28533143/drugs-in-space-pharmacokinetics-and-pharmacodynamics-in-astronauts
#2
Johannes Kast, Yichao Yu, Christoph N Seubert, Virginia E Wotring, Hartmut Derendorf
Space agencies are working intensely to push the current boundaries of human spaceflight by sending astronauts deeper into space than ever before, including missions to Mars and asteroids. Spaceflight alters human physiology due to fluid shifts, muscle and bone loss, immune system dysregulation, and changes in the gastrointestinal tract and metabolic enzymes. These alterations may change the pharmacokinetics and/or pharmacodynamics of medications used by astronauts and subsequently might impact drug efficacy and safety...
May 19, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28513545/a-study-on-immersion-and-presence-of-a-portable-hand-haptic-system-for-immersive-virtual-reality
#3
Mingyu Kim, Changyu Jeon, Jinmo Kim
This paper proposes a portable hand haptic system using Leap Motion as a haptic interface that can be used in various virtual reality (VR) applications. The proposed hand haptic system was designed as an Arduino-based sensor architecture to enable a variety of tactile senses at low cost, and is also equipped with a portable wristband. As a haptic system designed for tactile feedback, the proposed system first identifies the left and right hands and then sends tactile senses (vibration and heat) to each fingertip (thumb and index finger)...
May 17, 2017: Sensors
https://www.readbyqxmd.com/read/28505115/photosensor-based-latency-measurement-system-for-head-mounted-displays
#4
Min-Woo Seo, Song-Woo Choi, Sang-Lyn Lee, Eui-Yeol Oh, Jong-Sang Baek, Suk-Ju Kang
In this paper, a photosensor-based latency measurement system for head-mounted displays (HMDs) is proposed. The motion-to-photon latency is the greatest reason for motion sickness and dizziness felt by users when wearing an HMD system. Therefore, a measurement system is required to accurately measure and analyze the latency to reduce these problems. The existing measurement system does not consider the actual physical movement in humans, and its accuracy is also very low. However, the proposed system considers the physical head movement and is highly accurate...
May 15, 2017: Sensors
https://www.readbyqxmd.com/read/28502398/correlations-between-individual-susceptibility-to-visually-induced-motion-sickness-and-decaying-time-constant-of-after-nystagmus
#5
Coco C T Guo, Daniel J Z Chen, Isabella Y Wei, Richard H Y So, Raymond T F Cheung
This study examines the correlations between optokinetic after-nystagmus (OKAN) parameters and individual susceptibility to visually induced motion sickness (VIMS). Twenty-seven participants were exposed to vertical black-and-white stripes drifting along the yaw axis at 60° per second for 30 min to collect individual VIMS data (Phase 1). Two weeks after the exposure, OKANs were measured (Phase 2). 19 out of 27 participants (i.e., 70%) exhibited consistent OKAN patterns. Significant correlations between the time constants of OKAN and levels of VIMS experienced by the same viewers were found...
September 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28489651/the-impact-of-cervical-musculoskeletal-disorders-on-uk-consultant-plastic-surgeons-can-we-reduce-morbidity-with-applied-ergonomics
#6
Yvette Godwin, Christopher R Macdonald, Sarbjit Kaur, Li Zhelin, Christopher Baber
BACKGROUND: Based on anecdotal and observational evidence, we hypothesized that the prevalence of cervical musculoskeletal disorder (C-MSD) would be high among plastic surgeons. A questionnaire review was undertaken to test this hypothesis. Ergonomic assessment was undertaken to assess causal factors of C-MSD. METHOD: An anonymous questionnaire recording demographics, physical symptoms and behavioral responses to C-MSD was distributed to UK Plastic Surgery consultants...
June 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28455665/cross-coupling-vestibular-stimulation-motion-sickness-and-the-vestibulo-sympathetic-reflex
#7
Fausto Romano, Nicoletta Caramia, Dominik Straumann, Eugene Nalivaiko, Giovanni Bertolini
Motion sickness is associated with a variety of autonomic symptoms, presumably due to proximity or functional interconnectivity between the autonomic centers in the brainstem and the vestibular system. A direct influence of the vestibular system on cardiovascular variables, defined as the vestibulo-sympathetic reflex, has been reported previously. Our aim was to investigate the sudomotor components of the autonomic responses associated with motion sickness during passive cross-coupling stimulation ("roll while rotating")...
April 28, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28439720/the-impact-of-oral-promethazine-on-human-whole-body-motion-perceptual-thresholds
#8
Ana Diaz-Artiles, Adrian J Priesol, Torin K Clark, David P Sherwood, Charles M Oman, Laurence R Young, Faisal Karmali
Despite the widespread treatment of motion sickness symptoms using drugs and the involvement of the vestibular system in motion sickness, little is known about the effects of anti-motion sickness drugs on vestibular perception. In particular, the impact of oral promethazine, widely used for treating motion sickness, on vestibular perceptual thresholds has not previously been quantified. We examined whether promethazine (25 mg) alters vestibular perceptual thresholds in a counterbalanced, double-blind, within-subject study...
April 24, 2017: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/28428911/early-rehabilitation-of-distal-radius-fractures-stabilized-by-volar-locking-plate-a-prospective-randomized-pilot-study
#9
Stefan Quadlbauer, Christoph Pezzei, Josef Jurkowitsch, Brigitta Kolmayr, Tina Keuchel, Daniel Simon, Thomas Hausner, Martin Leixnering
Background Distal radius fractures are very common and an increased incidence of 50% is estimated by 2030. Therefore, both operative and postsurgical treatment remains pertinent. Main aim in treating intra-articular fractures is to restore the articular surface by internal fixation and early mobilization (EM). Questions/Purposes The purpose of this study was to compare functional results between EM immediately after surgery and 5 weeks of immobilization (IM). Patients and Methods In a randomized prospective study, 30 patients with an isolated distal radius fracture were treated by open reduction and internal fixation using a single volar locking plate excluding bone graft...
May 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28421029/a-historical-view-of-motion-sickness-a-plague-at-sea-and-on-land-also-with-military-impact
#10
Doreen Huppert, Judy Benson, Thomas Brandt
Seasickness and its triggers, symptoms, and preventive measures were well known in antiquity. This chapter is based on an analysis of descriptions of motion sickness, in particular seasickness, in ancient Greek, Roman, and Chinese literature. A systematic search was made from the Greek period beginning with Homer in 800 BC to the late Roman period and ending with Aetios Amidenos in 600 AD, as well as in the Chinese medical classics dating from around 300 AD. Major aspects are the following: body movements caused by waves were identified in all cultures as the critical stimuli...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28403892/lipids-bearing-extruded-spheronized-pellets-for-extended-release-of-poorly-soluble-antiemetic-agent-meclizine-hcl
#11
Faaiza Qazi, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Muhammad Iqbal Nasiri, Kamran Ahmed, Mansoor Ahmad
BACKGROUND: Antiemetic agent Meclizine HCl, widely prescribed in vertigo, is available only in immediate release dosage forms. The approved therapeutic dose and shorter elimination half-life make Meclizine HCl a potential candidate to be formulated in extended release dosage form. This study was aimed to develop extended release Meclizine HCl pellets by extrusion spheronization using natural and synthetic lipids. Influence of lipid type, drug/lipid ratio and combinations of different lipids on drug release and sphericity of pellets were evaluated...
April 12, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28395603/chemotherapy-induced-nausea-and-vomiting-cinv-in-190-colorectal-cancer-patients-a-prospective-registration-study-by-the-cinv-study-group-of-japan
#12
Yasushi Tsuji, Hideo Baba, Koji Takeda, Michiya Kobayashi, Eiji Oki, Masahiro Gotoh, Kazuhiro Yoshida, Mototsugu Shimokawa, Yoshihiro Kakeji, Keisuke Aiba
OBJECTIVES: Chemotherapy is an indispensable therapeutic approach for colorectal cancer both in the adjuvant and metastatic setting. Although chemotherapy-induced nausea and vomiting (CINV) is one of the most crucial adverse events, many aspects of CINV in patients with colorectal cancer remain unclear. METHODS: This multicenter, prospective, observational study analyzed the data of 190 colorectal cancer patients scheduled for moderately emetogenic chemotherapy (MEC)...
June 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28390649/abbreviated-closure-for-remote-damage-control-laparotomy-in-extreme-environments-a-randomized-trial-of-sutures-versus-wound-clamps-comparing-terrestrial-and-weightless-conditions
#13
Andrew W Kirkpatrick, Jessica Lynn McKee, Colonel Homer Tien, Anthony J LaPorta, Kit Lavell, Tim Leslie, Paul B McBeth, Derek J Roberts, Chad G Ball
INTRODUCTION: Far-Forward Damage Control Laparotomies (DCLs) might provide direct-compression of visceral hemorrhage, however, suturing is a limiting factor, especially for non-physicians. We thus compared abbreviated skin closures comparing skin-suture (SS) versus wound-clamp (WC), on-board a research aircraft in weightlessness (0g) and normal gravity (1g). METHODS: Surgeons conducted DCLs on a surgical-simulator; onboard the hangered-aircraft (1g), or during parabolic flight (0g), randomized to either WC or SS...
May 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28387168/numerical-simulation-of-motion-and-deformation-of-healthy-and-sick-red-blood-cell-through-a-constricted-vessel-using-hybrid-lattice-boltzmann-immersed-boundary-method
#14
Amir Hassanzadeh, Nader Pourmahmoud, Abdolrahman Dadvand
In the present article, hybrid lattice Boltzmann-immersed boundary method is utilized to simulate two-dimensional incompressible viscous flow involving flexible immersed red blood cell (RBC) in a microchannel. The main focus of the present research is to study motion and deformation of both healthy and sick RBCs in a vessel with different sizes of stenosis. The presented computational results consent reasonably well with the available data in the literature. Two different channels i.e. a simple and a constricted channel are investigated in the present manuscript...
May 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28380077/vection-is-the-main-contributor-to-motion-sickness-induced-by-visual-yaw-rotation-implications-for-conflict-and-eye-movement-theories
#15
Suzanne A E Nooij, Paolo Pretto, Daniel Oberfeld, Heiko Hecht, Heinrich H Bülthoff
This study investigated the role of vection (i.e., a visually induced sense of self-motion), optokinetic nystagmus (OKN), and inadvertent head movements in visually induced motion sickness (VIMS), evoked by yaw rotation of the visual surround. These three elements have all been proposed as contributing factors in VIMS, as they can be linked to different motion sickness theories. However, a full understanding of the role of each factor is still lacking because independent manipulation has proven difficult in the past...
2017: PloS One
https://www.readbyqxmd.com/read/28379057/metoclopramide-nasal-spray-in-vitro-evaluation-and-in-vivo-pharmacokinetic-studies-in-dogs
#16
Ying Li, Xianpeng Fan, Wanqing Li, Peng Yang, Hui Zhang, Daoquan Tang, Xiaoxin Yin, Jianxu Sun, Aiping Zheng
Metoclopramide (MCP) can effectively alleviate motion sickness-caused nausea and vomiting. Nasal administration offers the greatest patient compliance. It is suitable for self-administration and offers rapid and complete absorption, no first-pass effects, and high bioavailability. In present study, a MCP nasal spray was prepared and evaluated in vitro and in vivo. Nasal cilia toxicity of Bufo toads was used to screen the preservative types and concentrations. Rabbit nasal mucosa was used to evaluate the mucosa permeability of different MCP nasal sprays with different penetration enhancers and preservative...
April 5, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28378077/new-dimensions-in-surgical-training-immersive-virtual-reality-laparoscopic-simulation-exhilarates-surgical-staff
#17
Tobias Huber, Markus Paschold, Christian Hansen, Tom Wunderling, Hauke Lang, Werner Kneist
INTRODUCTION: Virtual reality (VR) and head mount displays (HMDs) have been advanced for multimedia and information technologies but have scarcely been used in surgical training. Motion sickness and individual psychological changes have been associated with VR. The goal was to observe first experiences and performance scores using a new combined highly immersive virtual reality (IVR) laparoscopy setup. METHODS: During the study, 10 members of the surgical department performed three tasks (fine dissection, peg transfer, and cholecystectomy) on a VR simulator...
April 4, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28372932/relationship-between-the-incidence-and-risk-factors-of-postoperative-nausea-and-vomiting-in-patients-with-intravenous-patient-controlled-analgesia
#18
Myung Sub Yi, Hyun Kang, Min Kyoung Kim, Geun-Joo Choi, Yong-Hee Park, Chong Wha Baek, Yong Hun Jung, Young Cheol Woo
OBJECTIVE: This study aims to evaluate retrospectively the electronic medical records of surgical patients who received intravenous patient-controlled analgesia, to identify potential relationships between the incidence and risk factors of postoperative nausea and vomiting (PONV). METHODS: Records of 6773 adult patients who received fentanyl-based intravenous patient-controlled analgesia after surgery at Chung-Ang University Hospital between January 1, 2010 and December 31, 2015 were reviewed...
March 31, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28356241/virtual-reality-for-management-of-pain-in-hospitalized-patients-results-of-a-controlled-trial
#19
Vartan C Tashjian, Sasan Mosadeghi, Amber R Howard, Mayra Lopez, Taylor Dupuy, Mark Reid, Bibiana Martinez, Shahzad Ahmed, Francis Dailey, Karen Robbins, Bradley Rosen, Garth Fuller, Itai Danovitch, Waguih IsHak, Brennan Spiegel
BACKGROUND: Improvements in software and design and reduction in cost have made virtual reality (VR) a practical tool for immersive, three-dimensional (3D), multisensory experiences that distract patients from painful stimuli. OBJECTIVE: The objective of the study was to measure the impact of a onetime 3D VR intervention versus a two-dimensional (2D) distraction video for pain in hospitalized patients. METHODS: We conducted a comparative cohort study in a large, urban teaching hospital in medical inpatients with an average pain score of ≥3/10 from any cause...
March 29, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28318502/efficacy-of-virtual-reality-in-pedestrian-safety-research
#20
Shuchisnigdha Deb, Daniel W Carruth, Richard Sween, Lesley Strawderman, Teena M Garrison
Advances in virtual reality technology present new opportunities for human factors research in areas that are dangerous, difficult, or expensive to study in the real world. The authors developed a new pedestrian simulator using the HTC Vive head mounted display and Unity software. Pedestrian head position and orientation were tracked as participants attempted to safely cross a virtual signalized intersection (5.5 m). In 10% of 60 trials, a vehicle violated the traffic signal and in 10.84% of these trials, a collision between the vehicle and the pedestrian was observed...
March 16, 2017: Applied Ergonomics
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