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https://www.readbyqxmd.com/read/28535270/intrinsically-photosensitive-retinal-ganglion-cell-function-sleep-efficiency-and-depression-in-advanced-age-related-macular-degeneration
#1
Michelle L Maynard, Andrew J Zele, Anthony S Kwan, Beatrix Feigl
Purpose: Melanopsin expressing intrinsically photosensitive retinal ganglion cells (ipRGC) input to multiple brain regions including those for pupil control, circadian rhythms, sleep and mood regulation. Here we measured ipRGC function and its relationship to sleep quality and depression in patients with advanced AMD. Methods: The melanopsin-mediated post-illumination pupil response (PIPR) was measured in 53 patients with advanced AMD (age 78.8 ± 8.8 years) and in 20 healthy controls (age 72...
February 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28532934/effects-of-topical-ketorolac-tromethamine-0-45-on-intraoperative-miosis-and-prostaglandin-e2-release-during-femtosecond-laser-assisted-cataract-surgery
#2
Jong Hwa Jun, Young-Sik Yoo, Sung A Lim, Choun-Ki Joo
PURPOSE: To determine the effects of topical 0.45% ketorolac tromethamine on intraoperative miosis and prostaglandin E2 (PGE2) release during femtosecond laser-assisted cataract surgery. SETTING: Seoul St. Mary's Hospital, Seoul, Korea. DESIGN: Prospective case series. METHODS: The study comprised the following 3 groups: conventional cataract surgery without topical NSAIDs (conventional group); femtosecond laser-assisted cataract surgery with preoperative topical ketorolac tromethamine 0...
April 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28532915/endoscopic-third-ventriculostomy-outcome-analysis-of-an-anterior-entry-point
#3
Mohammed Aref, Amanda Martyniuk, Siddharth Nath, Alex Koziarz, Jetan Badhiwala, Almunder Algird, Forough Farrokhyar, Saleh A Almenawer, Kesava Reddy
BACKGROUND: Endoscopic third ventriculostomy (ETV) is a safe and effective treatment for hydrocephalus. An entry point located 4 cm anterior to the coronal suture, 3 cm anterior to Kocher's point, and approximately 9 cm from the pupil at the mid-pupillary line, has been used successfully for the past 20 years in our center. We aimed to evaluate this alternative anterior entry point routinely used for ETV, with or without concurrent endoscopic biopsy. METHODS: Patients undergoing this proposed entry point were examined to evaluate its safety and efficacy...
May 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28532283/the-feasibility-of-an-automated-eye-tracking-modified-fagan-test-of-memory-for-human-faces-in-younger-ugandan-hiv-exposed-children
#4
Ronak Chhaya, Jonathan Weiss, Victoria Seffren, Alla Sikorskii, Paula M Winke, Julius C Ojuka, Michael J Boivin
OBJECTIVE: The Fagan Test of Infant Intelligence (FTII) uses longer gaze length for unfamiliar versus familiar human faces to gauge visual-spatial encoding, attention, and working memory in infants. Our objective was to establish the feasibility of automated eye tracking with the FTII in HIV-exposed Ugandan infants. METHOD: The FTII was administered to 31 perinatally HIV-exposed noninfected (HEU) Ugandan children 6-12 months of age (11 boys; M = 0.69 years, SD = 0...
May 22, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28531238/education-on-organ-donation-and-transplantation-in-primary-school-teachers-support-and-the-first-results-of-a-teaching-module
#5
Marion J Siebelink, A A Eduard Verhagen, Petrie F Roodbol, Marcel J I J Albers, Harry B M Van de Wiel
Organ and tissue donation can also involve children. Because of its sensitivity, this topic requires careful decision making. Children have the ability to carefully reflect on this subject and enjoy participating in family discussions about it. Therefore, what children need is proper information. When schools are used to educate children about this subject, information about teacher support for this type of lesson along with its effects on the depth of family discussions is important. METHODS: A questionnaire was sent to all 7,542 primary schools in the Netherlands...
2017: PloS One
https://www.readbyqxmd.com/read/28530080/-cataract-surgery-complications-in-males-treated-with-alpha-1-antagonists-for-benign-prostatic-hyperplasia
#6
REVIEW
Tamar Pedut Kloizman, Raneen Shehadeh Mashour
Intraoperative floppy iris syndrome (IFIS) was first described by Chang and Campbell in 2005. The characteristics of this syndrome include: 1. Floppy iris that billows in reaction to intraocular fluid currents during standard phacoemulsification procedure; 2. Flaccid iris stroma that tends to prolapse through well-constructed surgical incisions; 3. Insufficient pupillary mydriasis despite proper pharmacologic preparation and progressive pupillary constriction during the operation. Surgical procedures with IFIS have since been noted to have an exceptionally high rate of complications, some of which can be vision threatening...
September 2016: Harefuah
https://www.readbyqxmd.com/read/28529392/school-composition-school-culture-and-socioeconomic-inequalities-in-young-people-s-health-multi-level-analysis-of-the-health-behaviour-in-school-aged-children-hbsc-survey-in-wales
#7
Graham F Moore, Hannah J Littlecott, Rhiannon Evans, Simon Murphy, Gillian Hewitt, Adam Fletcher
Health inequalities emerge during childhood and youth, before widening in adulthood. Theorising, testing and interrupting the mechanisms through which inequalities are perpetuated and sustained is vital. Schools are viewed as settings through which inequality in young people's health may be addressed, but few studies examine the social processes via which institutional structures reproduce or mitigate health inequalities. Informed by Markham and Aveyard's theory of human functioning and school organisation, including their concept of institutional boundaries, critical theories of marketisation and the concept of micro-political practices within schools, this paper presents analysis of student survey data (N = 9055) from 82 secondary schools in Wales...
April 2017: British Educational Research Journal
https://www.readbyqxmd.com/read/28528120/objective-evaluation-of-corneal-and-lens-clarity-in-children-with-type-1-diabetes-mellitus
#8
Kemal Tekin, Merve Inanc, Erdal Kurnaz, Elvan Bayramoglu, Emre Aydemir, Mustafa Koc, Zehra Aycan
PURPOSE: To investigate whether abnormal glucose metabolism and duration of diabetes mellitus (DM) affected the corneal and lens clarity in children with well-controlled Type 1 DM and to compare the results obtained with those in healthy children. DESIGN: Cross-sectional prospective study. METHODS: This multicenter study enrolled 56 patients with DM and 51 control subjects. The duration of DM and the glycosylated hemoglobin (HbA1c) levels of the patients in the DM group were recorded...
May 17, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28528076/systematic-review-can-non-mydriatic-cameras-accurately-detect-diabetic-retinopathy
#9
REVIEW
Chloe Bedard, Siying Sherry Liu, Christopher Patterson, Hertzel Gerstein, Lauren Griffith
AIMS: Diabetes puts many individuals at risk for developing diabetic retinopathy (DR). Non-mydriatic (NM) retinal photography without pharmacological pupil dilation can be used to detect DR, however, its value in a general clinical setting has not been established. The objective of this review is to evaluate the validity of NM retinal photos, as compared to the reference standard of seven standard stereoscopic 30 degree field photographs (7SF), for their use of detecting DR in community-dwelling adults...
May 10, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28527817/lymphatic-filariasis-elimination-efforts-in-rufiji-south-eastern-tanzania-decline-in-circulating-filarial-antigen-prevalence-in-young-school-children-after-twelve-rounds-of-mass-drug-administration-and-utilization-of-long-lasting-insecticide-treated-nets
#10
Clarer Jones, Billy Ngasalla, Yahya A Derua, Donath Tarimo, Mwelecele N Malecela
BACKGROUND: Lymphatic filariasis (LF) is a parasitic infection transmitted by mosquito vectors and in sub Saharan Africa it is caused by nematode Wuchereria bancrofti. The disease has been targeted for global elimination by using annual mass drug administration (MDA) strategy. On the other hand, vector control is known to play important complementary role to the MDAs in reducing LF transmission. We report the findings of the effect of MDA and ITNs intervention implemented in endemic area of south-eastern Tanzania METHODS: A cross-sectional study for W...
May 17, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28527550/high-variance-in-pupillary-examination-findings-among-postanesthesia-care-unit-nurses
#11
Lilian Omburo, Sonja Stutzman, Charlene Supnet, Mica Choate, DaiWai M Olson
PURPOSE: On arrival to the postanesthesia care unit (PACU), patients are observed closely for significant neurological status changes. In particular, patients require frequent neurological examinations, which include assessment of the pupils for changes and/or abnormalities. DESIGN: This is a prospective, nonrandomized, observational study to examine the findings of pupillary examinations by nurses using different light sources in patients with existing pupillary assessments as ordered by standard of care...
June 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28524817/functional-dissociation-of-stimulus-intensity-encoding-and-predictive-coding-of-pain-in-the-insula
#12
Stephan Geuter, Sabrina Boll, Falk Eippert, Christian Büchel
The computational principles by which the brain creates a painful experience from nociception are still unknown. Classic theories suggest that cortical regions either reflect stimulus intensity or additive effects of intensity and expectations, respectively. By contrast, predictive coding theories provide a unified framework explaining how perception is shaped by the integration of beliefs about the world with mismatches resulting from the comparison of these believes against sensory input. Using functional magnetic resonance imaging during a probabilistic heat pain paradigm, we investigated which computations underlie pain perception...
May 19, 2017: ELife
https://www.readbyqxmd.com/read/28523059/efficacy-and-safety-of-optic-nerve-sheath-fenestration-in-patients-with-raised-intracranial-pressure
#13
Muhammad Amer Yaqub, Mohammad Asim Mehboob, Qamar Ul Islam
OBJECTIVE: To evaluate the efficacy and safety of Optic Nerve Sheath Fenestration (ONSF) in patients with raised intracranial pressure (ICP). METHODS: This Quasi Experimental Study was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi from July 2013 to July 2015. Thirty one eyes of 18 patients who underwent ONSF for raised ICP were followed up for one year to ascertain efficacy and safety of ONSF procedure. RESULTS: Thirteen (72...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28522252/optical-quality-of-rotationally-symmetrical-contact-lenses-derived-from-their-power-profiles
#14
Antonio J Del Águila-Carrasco, Daniel Monsálvez-Romín, Eleni Papadatou
PURPOSE: To present a methodology for evaluating the optical quality of rotationally symmetrical contact lenses (CLs) from a single power profile. METHODS: Simulated rotationally symmetrical power profiles corresponding to different CLs designs (monofocal, two-zone center-near bifocal, and four-zone center-distance bifocal) were used to calculate the wavefront error profile by means of numerical integration. Then, each lens wavefront error profile was spun around the center to obtain the lens wavefront error surface...
May 15, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28516453/dba-2j-mouse-model-for-experimental-glaucoma-pitfalls-and-problems
#15
Anita J Turner, Roshana Vander Wall, Vivek Gupta, Alex Klistorner, Stuart L Graham
PURPOSE: The DBA/2J mouse has been described as a model for congenital experimental glaucoma. It develops anterior segment anomalies with synechiae and pigment dispersion leading to raised intraocular pressure (IOP) and glaucomatous damage. However there are serious practical considerations when using this model in longitudinal studies. METHODS: We followed 118 mice from 12 - 48 weeks of age in a pharmaceutical trial. Here we report on the findings in control animals (n=37)...
May 18, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28515685/pupillary-response-to-negative-emotional-stimuli-is-differentially-affected-in-meditation-practitioners
#16
Alejandra Vasquez-Rosati, Enzo P Brunetti, Carmen Cordero, Pedro E Maldonado
Clinically, meditative practices have become increasingly relevant, decreasing anxiety in patients and increasing antibody production. However, few studies have examined the physiological correlates, or effects of the incorporation of meditative practices. Because pupillary reactivity is a marker for autonomic changes and emotional processing, we hypothesized that the pupillary responses of mindfulness meditation practitioners (MP) and subjects without such practices (non-meditators (NM)) differ, reflecting different emotional processing...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28512503/massive-oculomotor-nerve-enlargement-a-case-of-presumed-schwannomatosis
#17
Laura Donaldson, Ryan Rebello, Amadeo Rodriguez
A 45-year-old man presented with a slowly progressive pupil-involving third nerve palsy. Magnetic resonance imaging (MRI) revealed a tubular lesion extending from the interpeduncular cistern through the cavernous sinus and into the left orbit where it branched into a superior and an inferior division, clearly outlining the anatomy of the third cranial nerve. Multiple other, less pronounced, enlarged cranial nerves were noted. The differential diagnosis included chronic inflammatory demyelinating polyneuropathy (CIDP), hereditary motor and sensory neuropathy (HMSN), neurofibromatosis (NF), and schwannomatosis...
June 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/28511602/evaluation-of-student-handwashing-practices-during-a-school-based-hygiene-program-in-rural-western-kenya-2007
#18
Genevieve La Con, Katharine Schilling, Julie Harris, Bobbie Person, Mercy Owuor, Lorraine Ogange, Sitnah Faith, Robert Quick
Unsafe drinking water and inadequate handwashing facilities in primary schools increase the risk of absenteeism due to diarrhea and respiratory infections. To mitigate these risks, we provided 28 schools in rural Western Kenya with handwashing and drinking water stations (containers with lids and taps on metal stands), bleach for water treatment, soap for handwashing, and educational materials. We observed the use of the water stations and assessed teachers' attitudes toward the intervention. Of 151 total handwashing stations, 69 (59%) were observed to have soap and water and treated drinking water 4 months after implementation; observations of pupils showed an increase in handwashing behavior in water stations located < 10 m, as compared with those >10 m, from latrines ( p < ...
January 2017: International Quarterly of Community Health Education
https://www.readbyqxmd.com/read/28505505/measuring-listening-related-effort-and-fatigue-in-school-aged-children-using-pupillometry
#19
Ronan McGarrigle, Piers Dawes, Andrew J Stewart, Stefanie E Kuchinsky, Kevin J Munro
Stress and fatigue from effortful listening may compromise well-being, learning, and academic achievement in school-aged children. The aim of this study was to investigate the effect of a signal-to-noise ratio (SNR) typical of those in school classrooms on listening effort (behavioral and pupillometric) and listening-related fatigue (self-report and pupillometric) in a group of school-aged children. A sample of 41 normal-hearing children aged 8-11years performed a narrative speech-picture verification task in a condition with recommended levels of background noise ("ideal": +15dB SNR) and a condition with typical classroom background noise levels ("typical": -2dB SNR)...
May 12, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28504528/the-importance-of-arousal-for-variation-in-working-memory-capacity-and-attention-control-a-latent-variable-pupillometry-study
#20
Nash Unsworth, Matthew K Robison
A great deal of prior research has examined the relation between working memory capacity (WMC) and attention control. The current study explored the role of arousal in individual differences in WMC and attention control. Participants performed multiple WMC and attention control tasks. During the attention control tasks participants were periodically probed regarding their current attentional state and both baseline and task-evoked pupillary responses were recorded as indicators of tonic arousal and phasic arousal because of attentional effort, respectively...
May 15, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
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