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antenatal corticosteroid

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https://www.readbyqxmd.com/read/28194395/gender-differences-in-respiratory-morbidity-and-mortality-of-preterm-neonates
#1
REVIEW
Courtney Denise Townsel, Sawyer F Emmer, Winston A Campbell, Naveed Hussain
For the past century, researchers have underscored the "disadvantage" observed in respiratory morbidity and mortality of male newborns. In this contemporary review, we examine gender differences in preterm infant respiratory morbidity and mortality specifically appraising differences in the very low birth weight (VLBW) population as well as the late preterm (LPT) population. In the era of postnatal surfactant and antenatal corticosteroids, the gender gap in neonatal outcomes has not narrowed. Structural, physiologic, and hormonal sex differences may be at the root of this disparity...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28166660/population-based-study-on-antenatal-corticosteroid-treatment-in-preterm-small-for-gestational-age-and-non-small-for-gestational-age-twin-infants
#2
Shlomit Riskin-Mashiah, Brian Reichman, David Bader, Amir Kugelman, Valentina Boyko, Liat Lerner-Geva, Arieh Riskin
OBJECTIVES: To assess the associations between antenatal corticosteroid use (ACU), mortality and severe morbidities in preterm, twin neonates and compare these between small for gestational-age (SGA) and non-SGA twins. MATERIALS AND METHODS: Population-based study using data collected by the Israel National Very Low Birth Weight infant database from 1995-2012, comprising twin infants of 24-31 weeks' gestation, without major malformations. Univariate and multivariable logistic regression analyses were performed...
February 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28157136/global-health-of-babies-and-children
#3
Susan Gennaro, Caitlin OʼConnor, Megan Marx
PURPOSE: We provide an overview of the health of neonates, infants, and children around the world. Issues in maximizing neonatal health are examined using the Sustainable Development Goals developed by the United Nations as a framework. RECOMMENDATIONS: Interventions that can help optimize neonatal, infant, and child health in the future are reviewed, including increasing preventative healthcare (immunizations, malaria prevention, exclusive breastfeeding for the first 6 months of life), enhancing point-of-care interventions (including umbilical cord care, antenatal corticosteroids if preterm birth is anticipated, and antibiotic therapy), enhancing nutritional interventions (to decrease diarrheal diseases and decrease wasting, stunting, and underweight), and building systems capacityClinical Implications: In an increasingly global world where wars, climate change, civil unrest, and economic uncertainty all influence health, it is important that nurses understand global health problems common for neonates, infants, and children and current recommendations to enhance their health...
February 1, 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28146161/providers-compliance-with-practice-guidelines-of-prenatal-and-neonatal-care-to-reduce-neonatal-mortality-2004-versus-2012
#4
Renata Jaccottet Freitas, Tiago Neuenfeld Munhoz, Iná da Silva Dos Santos, Flávio Sérgio Chiuchetta, Fernando Barros, Aline Coletto, Alicia Matijasevich
Objective: To evaluate providers' compliance with practice guidelines of prenatal and neonatal care in order to reduce neonatal mortality. Methods: Uncontrolled before-and-after study designed to evaluate changes that occurred between 2004 and 2012, after the interventions proposed by the Municipality Committee of Research on Child Deaths, Foetal and Maternal Death (COMAI) on the frequency of the process indicators for perinatal assistance improvement. A total of 254 patients were studied in 2004 and 259 patients in 2012...
October 2016: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/28130929/use-of-antenatal-corticosteroids-in-special-circumstances-a-comprehensive-review
#5
Everett F Magann, Kjell Haram, Songthip Ounpraseuth, Jan Helge Mortensen, Horace J Spencer, John C Morrison
OBJECTIVE: To determine in pregnancies complicated by preterm premature rupture of membranes (PPROM), hypertension, intrauterine growth restriction, multi-fetal gestations and pregnancies 23- 26 weeks≥ 34 weeks gestation whether antenatal corticosteroids benefit the fetus. DATA SOURCES: Literature review using PubMed, Web of Science, Clinical trials. gov, Cochrane Database of Systematic Reviews (1990 - 2015). METHODS OF STUDY SELECTION: Search terms linked special circumstances with corticosteroids...
January 28, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28130210/antenatal-management-in-fetal-and-neonatal-alloimmune-thrombocytopenia-a-systematic-review
#6
Dian Winkelhorst, Michael F Murphy, Andreas Greinacher, Nadine Shehata, Tamam Bakchoul, Edwin Massey, Jillian Baker, Lani Lieberman, Susano Tanael, Heather Hume, Donald M Arnold, Shoma Baidya, Gerald Bertrand, James Bussel, Mette Kjaer, Cécile Kaplan, Jens Kjeldsen-Kragh, Dick Oepkes, Greg Ryan
Several strategies can be used to manage fetal or neonatal alloimmune thrombocytopenia (FNAIT) in subsequent pregnancies. Serial fetal blood sampling (FBS) and intrauterine platelet transfusions (IUPT), and weekly maternal intravenous immunoglobulin infusion (IVIG), with or without additional corticosteroid therapy are common options, but the optimal management has not been determined. The aim of this systematic review was to assess antenatal treatment strategies for FNAIT. Four randomized controlled trials and twenty-two non-randomized studies were included...
January 27, 2017: Blood
https://www.readbyqxmd.com/read/28104401/leading-causes-of-preterm-delivery-as-risk-factors-for-intraventricular-hemorrhage-in-very-preterm-infants-results-of-the-epipage-2-cohort-study
#7
Marie Chevallier, Thierry Debillon, Veronique Pierrat, Pierre Delorme, Gilles Kayem, Mélanie Durox, François Goffinet, Stephane Marret, Pierre Yves Ancel
BACKGROUND: Intraventricular hemorrhage is a major risk factor for neurodevelopmental disabilities in preterm infants. However, few studies have investigated how pregnancy complications responsible for preterm delivery are related to intraventricular hemorrhage. OBJECTIVE: To investigate the association between the main causes of preterm delivery and intraventricular hemorrhage in very preterm infants born in France during 2011 between 22 and 31 weeks of gestation...
January 16, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28071860/using-antenatal-corticosteroids-in-pregnancies-when-there-is-a-risk-of%C3%A2-very%C3%A2-preterm-delivery
#8
EDITORIAL
Marina Cuttini
No abstract text is available yet for this article.
February 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28068594/prevention-of-spontaneous-preterm-birth-guidelines-for-clinical-practice-from-the-french-college-of-gynaecologists-and-obstetricians-cngof
#9
REVIEW
Loïc Sentilhes, Marie-Victoire Sénat, Pierre-Yves Ancel, Elie Azria, Guillaume Benoist, Julie Blanc, Gilles Brabant, Florence Bretelle, Stéphanie Brun, Muriel Doret, Chantal Ducroux-Schouwey, Anne Evrard, Gilles Kayem, Emeline Maisonneuve, Louis Marcellin, Stéphane Marret, Nicolas Mottet, Sabine Paysant, Didier Riethmuller, Patrick Rozenberg, Thomas Schmitz, Héloïse Torchin, Bruno Langer
In France, 60,000 neonates are born preterm every year (7.4%), half of them after the spontaneous onset of labor. Among preventable risk factors of spontaneous prematurity, only cessation of smoking is associated with decreased prematurity (level of evidence [LE]1). It is therefore recommended (Grade A). Routine screening and treatment of vaginal bacteriosis is not recommended in the general population (Grade A). The only population for which vaginal progesterone is recommended is that comprising asymptomatic women with singleton pregnancies, no history of preterm delivery, and a short cervix at 16-24 weeks of gestation (Grade B)...
December 30, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28062023/we-should-proceed-with-caution-when-it-comes-to-antenatal-corticosteroids-after-34-weeks
#10
Christina M Nowik, Gregory A L Davies, Graeme N Smith
The Society for Maternal-Fetal Medicine recently released a statement supporting the use of antenatal corticosteroids for women at high risk of late preterm birth. This followed a trend of increasing use of antenatal corticosteroids after 34 weeks' gestation, based on evidence for decreased respiratory morbidity. The absolute benefits, however, are relatively small. We should balance this against the possible long-term harms of corticosteroids after 34 weeks before expanding the indications for their antenatal use...
January 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28029463/-tocolysis-for-preterm-labor-without-premature-preterm-rupture-of-membranes
#11
M Doret, G Kayem
OBJECTIVES: To propose guidelines for clinical practice for tocolysis in preterm labor without premature preterm rupture of the membranes (PPROM). MATERIALS AND METHODS: Bibliographic searches were performed in the Medline and Cochrane databases and gynecologist and obstetricians' international society guidelines. It is important to note that most studies included women in preterm labour with and without PPROM. RESULTS: Compared with placebo, tocolytics are not associated with a reduction in neonatal mortality or morbidity (LE2)...
October 28, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/28026890/influence-of-the-interval-between-antenatal-corticosteroid-therapy-and-delivery-on-respiratory-distress-syndrome
#12
Ichiro Yasuhi, Mai Myoga, Sachie Suga, So Sugimi, Yasushi Umezaki, Masashi Fukuda, Hiroshi Yamashita, Nobuko Kusuda
AIM: In spite of the recommendation for rescue antenatal corticosteroids (ACS), the optimal time interval between primary and rescue courses has not been clearly demonstrated. The aim of this study was to determine the effects of the interval between a single ACS course and delivery on the incidence of respiratory distress syndrome (RDS). METHODS: In this retrospective study, we included singleton pregnant women who received a single course of ACS and delivered beyond 48 h after ACS administration between 24 and 33 weeks' gestation...
December 27, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27920342/experimentally-induced-preterm-birth-in-sheep-following-a-clinical-course-of-antenatal-betamethasone-effects-on-growth-and-long-term-survival
#13
Vivian B Nguyen, Robert De Matteo, Richard Harding, Aneta Stefanidis, Graeme R Polglase, M Jane Black
Preterm births account for approximately 10% of births worldwide, with the majority (∼80%) being moderate preterm. Our aim was to determine the effects of moderate preterm birth on survival and long-term growth of male and female offspring using an ovine model of preterm birth that was preceded by a clinically relevant dose of corticosteroids. Ewes were induced to deliver preterm or at term; those assigned to deliver preterm were administered antenatal betamethasone (11.4 mg, 2 doses, 24 hours apart). The growth (body weight and body dimensions) of offspring was monitored to adulthood (62 weeks) when the animals were humanely killed for organ collection...
December 5, 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27899362/antenatal-corticosteroids-for-maturity-of-term-or-near-term-fetuses-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#14
(no author information available yet)
No abstract text is available yet for this article.
November 29, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27891148/can-we-accurately-time-the-administration-of-antenatal-corticosteroids-for-preterm-labor
#15
Paola Aghajanian, Quy T Nguyen, Naomi H Greene, Kimberly D Gregory
Background. Accurate timing of antenatal corticosteroids (ACS) has resulted in improved neonatal outcomes. Objectives. Our primary objective was to determine predictors for optimal timing of ACS in women presenting with spontaneous preterm labor. Study Design. A retrospective cohort study of women receiving ACS for spontaneous preterm birth was conducted. Women were included if they presented with preterm labor or preterm premature rupture of membranes. Accurate timing of ACS was defined as administration within 7 days of delivery...
2016: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/27869739/perinatal-risk-factors-and-genu-valgum-conducive-to-the-onset-of-growing-pains-in-early-childhood
#16
Angelos Kaspiris, Efstathios Chronopoulos, Elias Vasiliadis
The most prevalent musculoskeletal disorder of childhood with unclear aetiology is growing pains (GPs). Anatomic deformities and factors that change bone turnover are implicated in GP pathophysiology. Perinatal risk factors alter the bone metabolism affecting the bone mineral density and content. The aim of our study was to analyze the relationship between GPs, knock knees and perinatal factors. The examined population consisted of 276 children aged 3-7 years. Among them, ten pairs of dizygotic twins were evaluated...
November 18, 2016: Children
https://www.readbyqxmd.com/read/27861707/investigating-antenatal-corticosteroid-clinical-guideline-practice-at-an-organisational-level
#17
Emma L McGoldrick, Julie A Brown, Katie M Groom, Caroline A Crowther
BACKGROUND: High-quality, evidence-based guidelines can improve the quality of health care and facilitate standardisation of practice within and across healthcare organisations. Limited information is known regarding existing antenatal corticosteroid (ACS) guideline practices within organisations across Australia and New Zealand. AIMS: To assess existing ACS clinical practice guidelines (CPG). To describe current organisational practice related to the production, implementation and renewal of CPG...
November 15, 2016: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27861467/antenatal-dexamethasone-vs-betamethasone-dosing-for-lung-maturation-in-fetal-sheep
#18
Augusto F Schmidt, Matthew W Kemp, Paranthaman S Kannan, Boris W Kramer, John P Newnham, Suhas G Kallapur, Alan H Jobe
BACKGROUND: Dexamethasone-phosphate (Dex-PO4) and the combination betamethasone-phosphate (Beta-PO4) + betamethasone-acetate (Beta-Ac) are the most used antenatal corticosteroids to promote fetal lung maturation. We compared fetal lung maturation induced by Beta-Ac+Beta-PO4, Dex-PO4, or Beta-PO4 alone. METHODS: Pregnant ewes received two intramuscular doses 24 h apart of 0.25 mg/kg/dose of Beta-Ac+Beta-PO4, Dex-PO4 or Beta-PO4; or 2 doses of 0.125 mg/kg/dose of Beta-PO4 at 6, 12, or 24 h intervals...
January 11, 2017: Pediatric Research
https://www.readbyqxmd.com/read/27836377/-prevention-of-spontaneous-preterm-birth-excluding-preterm-premature-rupture-of-membranes-guidelines-for-clinical-practice%C3%A2-%C3%A2-text-of-the-guidelines-short-text
#19
L Sentilhes, M-V Sénat, P-Y Ancel, E Azria, G Benoist, J Blanc, G Brabant, F Bretelle, S Brun, M Doret, C Ducroux-Schouwey, A Evrard, G Kayem, E Maisonneuve, L Marcellin, S Marret, N Mottet, S Paysant, D Riethmuller, P Rozenberg, T Schmitz, H Torchin, B Langer
OBJECTIVES: To determine the measures to prevent spontaneous preterm birth (excluding preterm premature rupture of membranes)and its consequences. MATERIALS AND METHODS: The PubMed database, the Cochrane Library and the recommendations from the French and foreign obstetrical societies or colleges have been consulted. RESULTS: In France, premature birth concerns 60,000 neonates every year (7.4 %), half of them are delivered after spontaneous onset of labor...
December 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27835691/surfactant-protein-a-and-b-gene-polymorphisms-and-risk-of-respiratory-distress-syndrome-in-late-preterm-neonates
#20
Maria-Eleni I Tsitoura, Eleana F Stavrou, Ioannis A Maraziotis, Kosmas Sarafidis, Aglaia Athanassiadou, Gabriel Dimitriou
BACKGROUND AND OBJECTIVES: Newborns delivered late-preterm (between 340/7 and 366/7 weeks of gestation) are at increased risk of respiratory distress syndrome (RDS). Polymorphisms within the surfactant protein (SP) A and B gene have been shown to predispose to RDS in preterm neonates. The aim of this study was to investigate whether specific SP-A and/or SP-B genetic variants are also associated with RDS in infants born late-preterm. METHODS: This prospective cross-sectional study included 56 late-preterm infants with and 60 without RDS...
2016: PloS One
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