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https://www.readbyqxmd.com/read/29454174/mastectomy-patterns-but-not-rates-are-changing-in-the-treatment-of-early-breast-cancer-experience-of-a-single-european-institution-on-2315-consecutive-patients
#1
Alessandro Fancellu, Valeria Sanna, Pietrina Cottu, Cladio F Feo, Antonio M Scanu, Giulia Farina, Antonio Bulla, Angela Spanu, Panagiotis Paliogiannis, Alberto Porcu
BACKGROUND: Recent literature reports that rates of mastectomy are increasing in early breast cancer. However, data from European institutions are limited and revealed conflicting results. We report on 15-year trends of mastectomy, mastectomy plus immediate reconstruction and contralateral prophylactic mastectomy (CPM) at an academic institution. METHODS: We identified women diagnosed with unilateral early breast cancer at stage 0-IIa, with tumour size ≤ 4 cm, between 2002 and 2016...
February 14, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29453871/examining-the-incidence-and-presentation-of-melanoma-in-the-cardiothoracic-transplant-population
#2
Charles J Puza, Adela R Cardones, Paul J Mosca
Importance: The immunosuppression vital to maintaining transplanted organs comes with an increased incidence of cutaneous neoplasms. Understanding the genesis of malignant melanoma (MM) in transplant subpopulations is necessary for adequate disease surveillance. Objective: To determine the incidence and timing of presentation of MM in the cardiothoracic (heart and/or lung) transplant (CTT) population. Design, Setting, and Participants: This was a retrospective cohort study of 1164 patients who underwent a CTT from 2001 through 2016 with a median follow-up time of 4...
February 16, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29453743/neuromuscular-control-deficits-and-the-risk-of-subsequent-injury-after-a-concussion-a-scoping-review
#3
REVIEW
David R Howell, Robert C Lynall, Thomas A Buckley, Daniel C Herman
An emerging area of research has identified that an increased risk of musculoskeletal injury may exist upon returning to sports after a sport-related concussion. The mechanisms underlying this recently discovered phenomenon, however, remain unknown. One theorized reason for this increased injury risk includes residual neuromuscular control deficits that remain impaired despite clinical recovery. Thus, the objectives of this review were: (1) to summarize the literature examining the relationship between concussion and risk of subsequent injury and (2) to summarize the literature for one mechanism with a theorized association with this increased injury risk, i...
February 17, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29453000/neoadjuvant-chemoradiation-shows-no-survival-advantage-to-chemotherapy-alone-in-stage-iiia-patients
#4
Seth B Krantz, Brian Mitzman, Waseem Lutfi, Kristine Kuchta, Chi-Hsiung Wang, John A Howington, Ki Wan Kim
BACKGROUND: For operable patients with clinical stage IIIA non-small cell lung cancer, the optimum neoadjuvant treatment strategy remains unclear. Our aim was to compare perioperative and long-term outcomes for patients receiving neoadjuvant chemoradiotherapy (NCRT) versus neoadjuvant chemotherapy (NCT) alone. METHODS: We queried the National Cancer Database to identify all patients with N2 and either T1-T2 non-small cell lung cancer who received either NCRT or NCT followed by lobectomy between 2006 and 2012...
February 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29452999/chylothorax-as-a-risk-factor-for-thrombosis-in-adults-a-proof-of-concept-study
#5
Sumedh S Hoskote, Hemang Yadav, Prashant Jagtap, Dennis A Wigle, Craig E Daniels
BACKGROUND: Postoperative chylothorax in children is associated with an increased risk of vascular thrombosis, hypothesized to be from loss of antithrombin into chylous fluid resulting in a hypercoagulable state. In adults, an increased thrombotic risk with chylothorax has not been described. Adults undergoing Ivor-Lewis esophagogastrectomy have two strong thrombotic risk factors-active malignancy and postoperative state-allowing for relative homogeneity in baseline thrombotic risk; therefore, we studied the association of chylothorax with thrombosis in this population...
February 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29451886/which-preferences-associate-with-school-performance-lessons-from-an-exploratory-study-with-university-students
#6
Daniel Horn, Hubert Janos Kiss
Success in life is determined to a large extent by school performance so it is important to understand the effect of the factors that influence it. In this exploratory study, in addition to cognitive abilities, we attempt to link measures of preferences with outcomes of school performance. We measured in an incentivized way risk, time, social and competitive preferences and cognitive abilities of university students to look for associations between these measures and two important academic outcome measures: exam results and GPA...
2018: PloS One
https://www.readbyqxmd.com/read/29451170/eus-fna-using-22g-nitinol-or-procore-needles-without-on-site-cytopathology
#7
Charing Ching Ning Chong, Anthony Yuen Bun Teoh, Raymond Shing Yan Tang, Anthony Wing Hung Chan, Enders Kwok Wai Ng, Paul Bo San Lai
Objectives: The project is aimed to compare the tissue sampling rate and the diagnostic accuracy rate of EUS-FNA using 22G nitinol and reverse bevel-tipped needles. Subjects and Methods: This was a prospective, randomized, crossover study in a tertiary academic hospital. All consecutive adult patients undergoing EUS-guided FNA for lesions > 2 cm were recruited. Patients fulfilling the inclusion and exclusion criteria underwent EUS-guided FNA using both needles in sequence...
January 2018: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/29451009/risk-factors-influencing-severity-of-attention-deficit-hyperactivity-disorder-in-a-sample-of-preparatory-school-students-in-cairo
#8
Hisham Ramy, Mona El Sheikh, Marwa Sultan, Rasha Bassim, Maissa Eid, Ramy Ali, Marwa El Missiry
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood psychiatric disorders. Severity of symptoms is associated with more behavioral problems, poor academic performance, and persistence of symptoms into adulthood. METHODS: To examine the clinical and social correlates that may be identified as risk factors associated with ADHD severity in a sample of adolescent ADHD school students. A total of 925 students were recruited from two public and two private schools from eastern Cairo...
February 1, 2018: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/29450453/the-association-of-age-with-clinical-presentation-and-comorbidities-of-pyoderma-gangrenosum
#9
Hovik J Ashchyan, Daniel C Butler, Caroline A Nelson, Megan H Noe, William G Tsiaras, Stephen J Lockwood, William D James, Robert G Micheletti, Misha Rosenbach, Arash Mostaghimi
Importance: Pyoderma gangrenosum is an inflammatory neutrophilic dermatosis. Current knowledge of this rare disease is limited owing to a lack of validated diagnostic criteria and large population studies. Objective: To evaluate the association of age with the clinical presentation and comorbidities of pyoderma gangrenosum. Design, Setting, and Participants: This was a multicenter retrospective cohort study performed at tertiary academic referral centers in urban settings...
February 14, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29450251/online-activities-prevalence-of-internet-addiction-and-risk-factors-related-to-family-and-school-among-adolescents-in-china
#10
Miao Xin, Jiang Xing, Wang Pengfei, Li Houru, Wang Mengcheng, Zeng Hong
Aims: To investigate the online activities, prevalence of Internet Addiction in relation to demographic characteristics and risk factors related to family and school among adolescents. Methods: A total of 6468 10-18 year old adolescents recruited from local schools in Guangzhou, China were selected by adopting multi-stage stratified random sampling (female/male: 2886/3582; mean age:13.78 ± 2.43). Participants completed a structured questionnaire. Results: The overall prevalence of Internet Addiction was 26...
June 2018: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29450245/video-game-addiction-and-psychological-distress-among-expatriate-adolescents-in-saudi-arabia
#11
Nazmus Saquib, Juliann Saquib, AbdulWaris Wahid, Abdulrahman Akmal Ahmed, Hamad Emad Dhuhayr, Mohamed Saddik Zaghloul, Mohammed Ewid, Abdulrahman Al-Mazrou
Introduction: Few studies have estimated screen time among Arab adolescents, and no studies, to date, have published data on addiction to video games or Internet games among Arab adolescents. This study aimed to assess the prevalence of addiction to video games and its correlation with mental health in a sample of expatriate high school students from the Al-Qassim region of Saudi Arabia. Methods: The survey was conducted in 2016 among 276 students enrolled in ninth through twelfth grades in the International Schools in Buraidah, Al-Qassim...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29449163/orthopaedic-surgery-residency-rotations-and-correlation-with-orthopaedic-in-training-examination-performance
#12
Aaron I Karlen, Erik J Solberg, Deborah S Quanbeck, Ann E Van Heest
OBJECTIVE: The Orthopaedic In-Training Examination (OITE) is administered annually and is used to assess medical knowledge of orthopedic surgery residents. Beginning in the 2013 to 2014 academic year, the ACGME expanded the postgraduate year (PGY)-1 curriculum from 3 to 6 months of orthopedic surgery rotations. The purpose of this study is to evaluate the effect of increased PGY-1 orthopedic surgery exposure on medical knowledge as measured by the OITE. DESIGN: From 2011 to 2013, 24 PGY-2 residents completed 3 months of PGY-1 orthopedic training (Group 1)...
February 12, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29448934/from-theoretical-concepts-to-policies-and-applied-programmes-the-landscape-of-integration-of-oral-health-in-primary-care
#13
Hermina Harnagea, Lise Lamothe, Yves Couturier, Shahrokh Esfandiari, René Voyer, Anne Charbonneau, Elham Emami
BACKGROUND: Despite its importance, the integration of oral health into primary care is still an emerging practice in the field of health care services. This scoping review aims to map the literature and provide a summary on the conceptual frameworks, policies and programs related to this concept. METHODS: Using the Levac et al. six-stage framework, we performed a systematic search of electronic databases, organizational websites and grey literature from 1978 to April 2016...
February 15, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29447891/parents-experiences-managing-their-child-s-complicated-postoperative-recovery
#14
Mary Purcell, Julie Longard, Jill Chorney, Paul Hong
OBJECTIVE: Tonsillectomy is commonly performed as same-day surgery and parents are heavily relied upon for management of children's postoperative recovery. The objective of this study was to provide an in-depth description of the experiences parents face when managing their child's complicated postoperative recoveries at home. METHODS: An exploratory qualitative study at an academic pediatric hospital in Eastern Canada was performed. Participants included 12 parents of children aged 3-6 years who underwent adeno/tonsillectomy and experienced unexpected outcomes or complications during the postoperative recovery period...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29446312/interactive-laboratory-classes-enhance-neurophysiological-knowledge-in-thai-medical-students
#15
Nicha Wongjarupong, Danai Niyomnaitham, Pitchamol Vilaisaktipakorn, Tanawin Suksiriworaboot, Shaun Peter Qureshi, Saknan Bongsebandhu-Phubhakdi
Interactive laboratory class (ILC) is a two-way communication teaching method that encourages students to correlate laboratory findings with materials from lectures. In Thai medical education, active learning methods are uncommon. This paper aims to establish 1) if ILCs would effectively promote physiology learning; 2) if effectiveness would be found in both previously academically high-performing and low-performing students; and 3) the acceptability of ILCs to Thai medical students as a novel learning method...
March 1, 2018: Advances in Physiology Education
https://www.readbyqxmd.com/read/29446193/impact-of-nonintrusive-clinical-decision-support-systems-on-laboratory-test-utilization-in-a-large-academic-centre
#16
Kevin P Eaton, Natasha Chida, Ariella Apfel, Leonard Feldman, Adena Greenbaum, Susan Tuddenham, Emily A Kendall, Amit Pahwa
BACKGROUND: The near-universal prevalence of electronic health records (EHRs) has made the utilization of clinical decision support systems (CDSS) an integral strategy for improving the value of laboratory ordering. Few studies have examined the effectiveness of nonintrusive CDSS on inpatient laboratory utilization in large academic centres. METHODS: Red blood cell folate, hepatitis C virus viral loads and genotypes, and type and screens were selected for study...
February 15, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29445882/procedure-rates-performed-by-emergency-medicine-residents-a-retrospective-review
#17
Joshua T Bucher, Christopher Bryczkowski, Grant Wei, Renee L Riggs, Anoop Kotwal, Brian Sumner, Jonathan V McCoy
BACKGROUND: The purpose of our study is to investigate rates of individual procedures performed by residents in our emergency medicine (EM) residency program. Different programs expose residents to different training environments. Our hypothesis is that ultrasound examinations are the most commonly performed procedure in our residency. METHODS: The study took place in an academic level I trauma center with multiple residency and fellowship programs including surgery, surgical critical care, trauma, medicine, pulmonary/critical care, anesthesiology and others...
February 14, 2018: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29444654/the-comparison-of-perceived-health-related-quality-of-life-between-australian-children-with-severe-specific-language-impairment-to-age-and-gender-matched-peers
#18
Kristy Nicola, Pauline Watter
BACKGROUND: Children with specific language impairment often present with multiple comorbidities, which may adversely affect both participation in play and academic performance, potentially impacting a child's health-related quality of life. This study 1) explored the suitability of the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales (PedsQL™) for use with a typically developing Australian control group, and 2) compared the health-related quality of life between a control group and Australian children with severe specific language impairment...
February 14, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29444651/perceived-health-and-work-environment-related-problems-and-associated-subjective-production-loss-in-an-academic-population
#19
Malin Lohela-Karlsson, Lotta Nybergh, Irene Jensen
BACKGROUND: The aim was to investigate the prevalence of health problems and work environment problems and how these are associated with subjective production loss among women and men at an academic workplace. An additional aim was to investigate whether there were differences between women and men according to age group, years at current workplace, academic rank or managerial position. METHODS: A questionnaire was sent in 2011 to all employees at a Swedish university (n = 5144)...
February 14, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29444478/detection-of-drug-safety-signals-from-clinical-trials-data-role-of-susars
#20
Christelle Perez, Pascale Olivier, Barbara Lortal, Sophie Duranton, Jean-Louis Montastruc, Anne-Laurène Colin, Emilie Toulza, Madlyne Becker, Laura Hamy, Sabrina Crepin, Caroline Roussillon, Anne Gimbert, Nadine Petitpain, Francesco Salvo
One of the main goals of safety management in clinical trials is to detect suspected unexpected serious adverse reactions (SUSARs). The unexpectedness concerns the nature, frequency or severity of an adverse reaction. Drug safety signals could thus be retrieved, and a study was performed to investigate whether SUSARs allow signal detection in pharmacovigilance. Data from six academic safety units were collected from 2005 to 2016. Characteristics of SUSARs were analysed and signals were identified i) by evaluating the presence of other causes, ii) by assessing the summary of product characteristics (SPC), iii) by searching for specific safety information in Pubmed and health agencies, and iv) by investigating the narrative of each case...
February 11, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
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