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https://www.readbyqxmd.com/read/28654959/cardiovascular-testing-and-clinical-outcomes-in-emergency-department-patients-with-chest-pain
#1
Alexander T Sandhu, Paul A Heidenreich, Jay Bhattacharya, M Kate Bundorf
Importance: Noninvasive testing and coronary angiography are used to evaluate patients who present to the emergency department (ED) with chest pain, but their effects on outcomes are uncertain. Objective: To determine whether cardiovascular testing-noninvasive imaging or coronary angiography-is associated with changes in the rates of coronary revascularization or acute myocardial infarction (AMI) admission in patients who present to the ED with chest pain without initial findings of ischemia...
June 26, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28651945/-return-to-sender-or-consider-it-done-the-importance-of-reducing-hospital-readmission-after-coronary-artery-bypass-grafting
#2
EDITORIAL
Peter Donndorf, Alexander Kaminski
No abstract text is available yet for this article.
May 19, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28651939/competitive-flow-in-coronary-bypass-surgery-the-roles-of-fractional-flow-reserve-and-arterial-graft-configuration
#3
EDITORIAL
Hugh S Paterson, Paul G Bannon, David P Taggart
No abstract text is available yet for this article.
June 3, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28651834/the-impact-of-care-management-information-technology-model-on-quality-of-care-after-coronary-artery-bypass-surgery-bridging-the-divides
#4
William S Weintraub, Daniel Elliott, Zaher Fanari, Jennifer Ostertag-Stretch, Ann Muther, Margaret Lynahan, Roger Kerzner, Tabassum Salam, Herbert Scherrer, Sharon Anderson, Carla A Russo, Paul Kolm, Terri H Steinberg
BACKGROUND: Reducing readmissions and improving metrics of care are a national priority. Supplementing traditional care with care management may improve outcomes. The Bridges program was an initial evaluation of a care management platform (CareLinkHub), supported by information technology (IT) developed to improve the quality and transition of care from hospital to home after Coronary Artery Bypass Surgery (CABG) and reduce readmissions. METHODS: CareLink is comprised of care managers, patient navigators, pharmacists and physicians...
June 21, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28651783/optimal-timing-of-heart-transplant-after-heartmate-ii-left-ventricular-assist-device-implantation
#5
Robert J Steffen, Eugene H Blackstone, Nicholas G Smedira, Edward G Soltesz, Katherine J Hoercher, Lucy Thuita, Randall C Starling, Maria Mountis, Nader Moazami
BACKGROUND: Optimal timing of heart transplantation in patients supported with second-generation left ventricular assist devices (LVADs) is unknown. Despite this, patients with LVADs continue to receive priority on the heart transplant waiting list. Our objective was to determine the optimal timing of transplantation for patients bridged with continuous-flow LVADs. METHODS: A total of 301 HeartMate II LVADs (Thoratec Corp, Pleasanton, CA) were implanted in 285 patients from October 2004 to June 2013, and 86 patients underwent transplantation through the end of follow-up...
June 24, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28651740/impact-of-prior-coronary-stenting-on-the-outcome-of-subsequent-coronary-artery-bypass-grafting
#6
Yu-Ting Cheng, Shao-Wei Chen, Chih-Hsiang Chang, Pao-Hsien Chu, Dong-Yi Chen, Victor Chien-Chia Wu, Kuo-Sheng Liu, Yu-Yun Nan, Feng-Chun Tsai, Pyng-Jing Lin
BACKGROUND: The percentage of patients referred for coronary artery bypass grafting (CABG) who have previously undergone percutaneous coronary interventions (PCIs) is increasing. The purpose of this study was to review the outcomes of patients who had received coronary stenting before CABG, and to examine the validity of a mortality risk stratification system in this patient group. METHODS: From 2010 to 2012, 439 patients who underwent isolated CABG at our medical center were reviewed...
June 2017: Biomedical Journal
https://www.readbyqxmd.com/read/28648540/pedicled-vein-grafts-in-coronary-operation-perioperative-data-from-a-randomized-trial
#7
Øystein Pettersen, Per Magnus Haram, Anders Winnerkvist, Asbjørn Karevold, Alexander Wahba, Maryann Stenvik, Rune Wiseth, Knut Hegbom, Dag Ole Nordhaug
BACKGROUND: Less-than-optimal long-term patency of the saphenous vein is one of the main obstacles for the success of coronary artery bypass grafting (CABG). Results from the IMPROVE-CABG trial has shown that harvesting the saphenous vein with a pedicle of perivascular tissue less than 5 mm while using manual distention provides comparable occlusion rates but significantly less intimal hyperplasia at early follow-up. The impact of pedicled veins on duration of operations, leg wound infections, and postoperative bleeding is unknown...
June 22, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28648536/outcomes-of-elective-aortic-hemiarch-reconstruction-for-aneurysmal-disease-in-the-elderly
#8
Arman Kilic, George J Arnaoutakis, Joseph E Bavaria, Ibrahim Sultan, Nimesh D Desai, Prashanth Vallabhajosyula, Matthew L Williams, Rita K Milewski, Wilson Y Szeto
BACKGROUND: This study evaluated outcomes of elective aortic hemiarch reconstruction for aneurysmal disease in the elderly. METHODS: Patients undergoing elective aortic hemiarch reconstruction for aneurysmal disease at a single institution between 2009 and 2014 were retrospectively reviewed. Patients were stratified into nonelderly (aged less than 75 years) versus elderly (aged 75 years or more). Outcomes included operative mortality and morbidity. RESULTS: In all, 629 patients (95 elderly; 15%) were included...
June 22, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28648480/a-10-year-institutional-experience-with-open-branched-graft-reconstruction-of-aortic-aneurysms-in-connective-tissue-disorders-versus-degenerative-disease
#9
Caitlin W Hicks, Jennifer Lue, Natalia O Glebova, Bryan A Ehlert, James H Black
OBJECTIVE: Aortic reconstruction for complex thoracoabdominal aortic aneurysms (TAAAs) can be challenging, especially in patients with connective tissue disorders (CTDs) in whom tissue fragility is a major concern. Branched graft reconstruction is a more complex operation compared with inclusion patch repair of the aorta but is frequently necessary in patients with CTDs or other pathologies because of anatomic reasons. We describe our institutional experience with open branched graft reconstruction of aortic aneurysms and compare outcomes for patients with CTDs vs degenerative pathologies...
June 22, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28648391/role-of-global-longitudinal-strain-in-the-prediction-of-outcome-in-patients-with-severe-aortic-valve-stenosis
#10
Bastian Fries, Dan Liu, Philipp Gaudron, Kai Hu, Peter Nordbeck, Georg Ertl, Frank Weidemann, Sebastian Herrmann
In the present study, we assessed the role of Global Longitudinal Strain (GLS) as a predictor of all-cause mortality in patients with severe aortic valve stenosis (AS), irrespective of their type of treatment. Data of 807 patients with AS receiving complete echocardiographic and clinical examination were retrospectively analyzed. Valve area <1 cm(2) and sufficient image quality were inclusion criteria; patients with severe concomitant valvulopathy were excluded. Patients were grouped into treatment (aortic valve replacement [AVR]) and conservative (non-AVR) groups...
May 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28648010/-experience-of-sun-s-procedure-for-chronic-type-b-dissection-with-aortic-arch-involvement
#11
R D Qi, J M Zhu, L Chen, C N Li, Z Y Qiao, L J Cheng, Y P Ge, H O Hu, Y Xia, X Y Xing, T Zheng, Y M Liu, L Z Sun
Objective: To study the surgical treatment of chronic type B dissection with aortic arch involvement using Sun's procedure. Methods: Between February 2009 and December 2015, 29 patients [20 males, 9 females, with a mean age of (41±12) years, range 24-64 years] with type B dissection with aortic arch involvement underwent Sun's procedure. Sixteen patient had a history of hypertension. Marfan syndrome was observed in 9 cases, coronary artery disease in 3 cases, mitral regurgitation in 3 patients, cerebrovascular disease in one patient...
June 27, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28647801/prognostic-factors-of-atrial-fibrillation-following-coronary-artery-bypass-graft-surgery
#12
Mantas Kievišas, Vytenis Keturakis, Egidijus Vaitiekūnas, Lukas Dambrauskas, Loreta Jankauskienė, Šarūnas Kinduris
OBJECTIVE: Postoperative atrial fibrillation (POAF) is the most common complication after cardiac surgery. To prevent this complication, routine pharmacological prophylactic drugs could be administered. Our study aimed to analyze the various perioperative factors associated with the development of POAF after coronary artery bypass graft (CABG) surgery. METHODS: This prospective study included 617 patients, who received CABG surgery in the year 2014. RESULTS: There were 429 (69...
June 24, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28647732/perioperative-strokes-following-surgical-correction-of-mitral-valves-a-systematic-review-and-meta-analysis
#13
Reshmi Udesh, Piruthiviraj Natarajan, Vinodh Jeevanantham, Thomas G Gleason, Vinay Badhwar, Parthasarathy D Thirumala
OBJECTIVE: The primary aim of this meta-analysis was to quantify the impact of perioperative strokes on stroke-related mortality after open mitral valve (MV) procedures were performed. METHODS: An electronic search of the PubMed, Embase, and the Web of Science databases was performed to retrieve articles published up to December 2015, relevant to patients undergoing MV procedures. Data were extracted from the final list of 25 studies to calculate a summary OR for 30-day stroke-related mortality...
June 24, 2017: European Neurology
https://www.readbyqxmd.com/read/28645858/vascular-adaptation-pattern-formation-and-cross-validation-between-an-agent-based-model-and-a-dynamical-system
#14
Marc Garbey, Stefano Casarin, Scott A Berceli
Myocardial infarction is the global leading cause of mortality (Go AS et al. 2014). Coronary artery occlusion is its main etiology and it is commonly treated by Coronary Artery Bypass Graft (CABG) surgery (Wilson CT 2007). The long-term outcome remains unsatisfactory (Benedetto U 2016). The vein faces the phenomenon of restenosis during the post-surgery, which consists of re-occlusion of the lumen and usually requires secondary intervention even within one year after the initial surgery (Harskamp RE 2013). We propose an extensive study of the restenosis phenomenon by implementing two mathematical models previously developed: a heuristic Dynamical System (DS) (Garbey M and Berceli SA 2013), and a stochastic Agent Based Model (ABM) (Garbey M et al...
June 20, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28644212/worsening-atrioventricular-conduction-after-hospital-discharge-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention-the-horizons-ami-trial
#15
Ioanna Kosmidou, Björn Redfors, Thomas McAndrew, Monica Embacher, Roxana Mehran, José M Dizon, Ori Ben-Yehuda, Gary S Mintz, Gregg W Stone
BACKGROUND: The chronic effects of ST-segment elevation myocardial infarction (STEMI) on the atrioventricular conduction (AVC) system have not been elucidated. This study aimed to evaluate the incidence, predictors, and outcomes of worsened AVC post-STEMI in patients treated with a primary percutaneous coronary intervention (PCI). PATIENTS AND METHODS: The current analysis included patients from the HORIZONS-AMI trial who underwent primary PCI and had available ECGs...
June 21, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28644211/the-relationship-between-fasting-blood-glucose-variability-and-coronary-artery-collateral-formation-in-type-2-diabetes-patients-with-coronary-artery-disease
#16
Gang Cheng, Hilda Mahmoudi, Binna Chokshi, Marlena Fernandez, Vahid Kazemi, Nader Lamaa
BACKGROUND: Coronary collaterals are an alternative source of blood supply to ischemic myocardium. Well-developed coronary collateral arteries in patients with coronary artery disease (CAD) limit the size of acute myocardial infarction and improves survival. The aim of this study was to investigate the relationship between glycemic variability and coronary collateral formation in patients with type 2 diabetes mellitus and CAD. METHODS: Consecutive patients undergoing percutaneous coronary intervention or coronary artery bypass grafting procedures were studied...
June 21, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28640111/comparative-safety-for-cardiovascular-outcomes-of-dpp-4-inhibitors-versus-glimepiride-in-patients-with-type-2-diabetes-a-retrospective-cohort-study
#17
Hyouk-Jun Chin, Jin Hyun Nam, Eui-Kyung Lee, Ju-Young Shin
Concerns about the cardiovascular safety of dipeptidyl peptidase-4 (DPP-4) inhibitors persist. This study sought to determine whether there is a differential risk of hospitalization for cardiovascular diseases (CVDs) between DPP-4 inhibitors and glimepiride.We conducted this retrospective cohort study by using the Korean National Health Insurance Service database from December 1, 2008, to December 31, 2013. The study subjects were new users of DPP-4 inhibitors or glimepiride for type 2 diabetes. Outcome was defined as hospitalization for CVDs, including angina pectoris, myocardial infarction, transient cerebral ischemic attack, heart failure, or cerebrovascular disease or any procedure involving coronary artery bypass grafting or percutaneous coronary intervention...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28639574/mir-551b-5p-contributes-to-pathogenesis-of-vein-graft-failure-via-upregulating-early-growth-response-1-expression
#18
Ran Dong, Kui Zhang, Yue-Li Wang, Feng Zhang, Jian Cao, Ju-Bing Zheng, Hong-Jia Zhang
BACKGROUND: Vein graft failure (VGF) is a serious complication of coronary artery bypass graft, although the mechanism remains unclear. The study aimed to investigate the effects of microRNAs (miRNAs) on the endothelial dysfunction involved in VGF. METHODS: Human umbilical vein endothelial cells (HUVECs) were subjected to mechanical stretch stimulation to induce endothelial dysfunction. Genome-wide transcriptome profiling was performed using the Human miRNA OneArray® V4 (PhalanxBio Inc...
July 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28639006/angiogenic-growth-factors-in-myocardial-infarction-a-critical-appraisal
#19
REVIEW
Hemalatha Thiagarajan, UmaMaheswari Thiyagamoorthy, Iswariya Shanmugham, Gunadharini Dharmalingam Nandagopal, Anbukkarasi Kaliyaperumal
In the recent past, substantial advances have been made in the treatment of myocardial infarction (MI). Despite the impact of these positive developments, MI remains to be a leading cause of morbidity as well as mortality. An interesting hypothesis is that the development of new blood vessels (angiogenesis) or the remodeling of preexisting collaterals may form natural bypasses that could compensate for the occlusion of an epicardial coronary artery. A number of angiogenic factors are proven to be elicited during MI...
June 21, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28638008/-the-results-of-pulmonary-veins-isolation-to-prevent-postoperative-atrial-fibrillation
#20
P V Lednev, Yu V Belov, R N Komarov, A V Stonogin, A I Katkov
AIM: To compare an efficacy of primary surgical (epicardial bipolar pulmonary veins isolation) and pharmacological (amiodarone) prevention of postoperative atrial fibrillation. MATERIAL AND METHODS: The study included 117 patients with coronary artery disease without previous paroxysms of atrial fibrillation who were randomized into 3 groups. The first (I) group (n=39) included patients who underwent coronary artery bypass grafting without radiofrequency ablation of pulmonary veins and prophylactic amiodarone administration...
2017: Khirurgiia
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