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https://www.readbyqxmd.com/read/28193553/an-investigation-of-reactivity-effect-due-to-inadvertent-filling-of-the-irradiation-channels-with-water-in-nirr-1-nigeria-research-reactor-1
#1
U Iliyasu, Y V Ibrahim, Sadiq Umar, S A Agbo, Y Jibrin
Investigation of reactivity variation due to flooding of the irradiation channels of Nigeria Research Reactor (NIRR-1) a low power miniature neutron source reactor (MNSR) located at the Centre for Energy Research and Training, Ahmadu Bello University, Zaria Nigeria using the MCNP code for High Enrich Uranium (HEU) and Low Enrich Uranium (LEU) core has been simulated in this present study. In this work, the excess reactivity worth of flooding HEU core for 1 inner, 2 inner, 3 inner, 4 inner and all inner are 0...
February 9, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28178906/research-benefits-of-storing-genitourinary-samples-16s-rrna-sequencing-to-evaluate-vaginal-bacterial-communities
#2
Josef Wagner, Sarah Kerry-Barnard, S T Sadiq, Pippa Oakeshott
No abstract text is available yet for this article.
March 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28161918/bowled-over-by-cricket-impact-of-tape-ball-injuries-on-the-eyes
#3
Salman Naveed Sadiq, Azam Ali, Bushra Usmani, Khabir Ahmad
PURPOSE: The aim of this study was to describe the type and severity of tape-ball cricket-related eye injuries seen at a tertiary care hospital. DESIGN: A descriptive case series. METHODS: This study included all cases of tape-ball cricket-related eye injuries presenting to the Section of Ophthalmology, Aga Khan University Hospital, Karachi, from January 2014 to January 2015. RESULTS: A total of 20 patients with tape-ball cricket-related eye injuries were treated during this period...
January 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28159916/impact-of-deploying-multiple-point-of-care-tests-with-a-sample-first-approach-on-a-sexual-health-clinical-care-pathway-a-service-evaluation
#4
Emma M Harding-Esch, Achyuta V Nori, Aseel Hegazi, Marcus J Pond, Olanike Okolo, Anthony Nardone, Catherine M Lowndes, Phillip Hay, S Tariq Sadiq
OBJECTIVES: To assess clinical service value of STI point-of-care test (POCT) use in a 'sample first' clinical pathway (patients providing samples on arrival at clinic, before clinician consultation). Specific outcomes were: patient acceptability; whether a rapid nucleic acid amplification test (NAAT) for Chlamydia trachomatis/Neisseria gonorrhoeae (CT/NG) could be used as a POCT in practice; feasibility of non-NAAT POCT implementation for Trichomonas vaginalis (TV) and bacterial vaginosis (BV); impact on patient diagnosis and treatment...
February 3, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28126287/synthesis-biological-evaluation-and-docking-studies-of-2-3-dihydroquinazolin-4-1h-one-derivatives-as-inhibitors-of-cholinesterases
#5
Muhammad Sarfraz, Nargis Sultana, Umer Rashid, Muhammad Safwan Akram, Abdul Sadiq, Muhammad Ilyas Tariq
In search of potent inhibitors of cholinesterases, we have synthesized and evaluate a number of 2,3-dihydroquinazolin-4(1H)-one derivatives. The synthetic approach provided an efficient synthesis of the target molecules with excellent yield. All the tested compounds showed activity against both the enzymes in micromolar range. In many case, the inhibition of both enzymes are higher than or comparable to the standard drug galatamine. With the selectivity index of 2.3 for AChE, compound 5f can be considered as a potential lead compound with a feature of dual AChE/BChE inhibition with IC50=1...
January 17, 2017: Bioorganic Chemistry
https://www.readbyqxmd.com/read/28109339/stigma-reduction-training-improves-healthcare-provider-attitudes-toward-and-experiences-of-young-marginalized-people-in-bangladesh
#6
Scott Geibel, Sharif M I Hossain, Julie Pulerwitz, Nargis Sultana, Tarik Hossain, Shongkour Roy, Brady Burnett-Zieman, Lucy Stackpool-Moore, Barbara A Friedland, Reena Yasmin, Najmus Sadiq, Eileen Yam
PURPOSE: Working with health providers to reduce HIV stigma in the healthcare setting is an important strategy to improve service utilization and quality of care, especially for young people who are sexually active before marriage, are sexual minorities, or who sell sex. A stigma reduction training program for health providers in Bangladesh was evaluated. METHODS: A cohort of 300 healthcare providers were given a self-administered questionnaire, then attended a 2-day HIV and sexual and reproductive health and rights training (including a 90-minute session on stigma issues)...
February 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28109337/paying-for-sex-by-young-men-who-live-on-the-streets-in-dhaka-city-compounded-sexual-risk-in-a-vulnerable-migrant-community
#7
Tracy L McClair, Tarik Hossain, Nargis Sultana, Brady Burnett-Zieman, Eileen A Yam, Sharif Hossain, Reena Yasmin, Najmus Sadiq, Michele R Decker, Saifuddin Ahmed
PURPOSE: Dhaka City is home to thousands of migrants from Bangladesh's rural areas who often live in the streets. Prior studies examine street youth's practice of selling sex as a survival mechanism. We assess their less-studied practice of paying for sex and its association with sexual risk behaviors and outcomes. METHODS: As part of the global Link Up project, trained interviewers recruited 447 young men who live on the streets, ages 15-24, from seven Dhaka City "hotspots" to participate in a survey about sexual health...
February 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28098806/antibacterial-activities-and-possible-modes-of-action-of-acacia-nilotica-l-del-against-multidrug-resistant-escherichia-coli-and-salmonella
#8
Muhammad Bilal Sadiq, Joel Tarning, Tay Zar Aye Cho, Anil Kumar Anal
Medicinal plants are frequently used for the treatment of various infectious diseases. The objective of this study was to evaluate the antibacterial activity and mode of action of Acacia nilotica and the antibiogram patterns of foodborne and clinical strains of Escherichia coli and Salmonella. The mechanism of action of acacia extracts against E. coli and Salmonella was elucidated by observing morphological damages including cell integrity and cell membrane permeability, as well as changes in cell structures and growth patterns in kill-time experiments...
January 14, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28078656/biosimilars-for-the-treatment-of-cancer-a-systematic-review-of-published-evidence
#9
REVIEW
Ira Jacobs, Reginald Ewesuedo, Sadiq Lula, Charles Zacharchuk
BACKGROUND: Biologic treatments for cancer continue to place a significant economic burden on healthcare stakeholders. Biosimilar therapies may help reduce this burden through cost savings, thereby increasing patient access. OBJECTIVES: The purpose of this study was to collate all published data to assess the weight of available evidence (quantity and quality) for proposed monoclonal antibody biosimilars and intended copies, for the treatment of cancer. METHODS: MEDLINE(®), Embase(®), and ISI Web of Science(®) databases were searched to September 2015...
February 2017: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://www.readbyqxmd.com/read/28077489/rescue-of-severe-brain-and-cervical-cord-iris-by-restarting-natalizumab-in-a-pregnant-ms-patient
#10
Thomas H Massey, Rachel Smith, Shaheena Sadiq, Christopher Overton, Owen R Pearson
No abstract text is available yet for this article.
January 11, 2017: Neurology
https://www.readbyqxmd.com/read/28070467/social-support-and-resilience-among-patients-with-burn-injury-in-lahore-pakistan
#11
Ahmed Waqas, Sadiq Naveed, Mariam M Bhuiyan, Jawad Usman, Ahmed Inam-Ul-Haq, Sara S Cheema
INTRODUCTION: Social support and ego resiliency play a great role in maintaining the physical and mental health of patients with burn injuries. The present study has been designed to compare ego resiliency levels and the degree of social support in patients with a burn injury and their healthy counterparts. METHODS: This study was conducted in two teaching hospitals in Lahore, Pakistan from May 2015 to July 2015. A total of 80 burn patients presenting in outpatient departments of general surgery, plastic surgery, and burn centers of these hospitals were surveyed conveniently, and for comparison, 80 patients presenting in outpatient departments with minor ailments, for routine checkups or follow-ups were recruited...
November 8, 2016: Curēus
https://www.readbyqxmd.com/read/28056166/nitric-oxide-for-respiratory-failure-in-infants-born-at-or-near-term
#12
REVIEW
Keith J Barrington, Neil Finer, Thomas Pennaforte, Gabriel Altit
BACKGROUND: Nitric oxide (NO) is a major endogenous regulator of vascular tone. Inhaled nitric oxide (iNO) gas has been investigated as treatment for persistent pulmonary hypertension of the newborn. OBJECTIVES: To determine whether treatment of hypoxaemic term and near-term newborn infants with iNO improves oxygenation and reduces rate of death and use of extracorporeal membrane oxygenation (ECMO), or affects long-term neurodevelopmental outcomes. SEARCH METHODS: We used the standard search strategy of the Cochrane Neonatal Review Group to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 1), MEDLINE via PubMed (1966 to January 2016), Embase (1980 to January 2016) and the Cumulative Index to Nursing and Allied Health Literature (CINAHL; 1982 to January 2016)...
January 5, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28018812/pneumopericardium-leading-to-cardiac-tamponade-in-a-patient-with-lung-cancer
#13
Ahmad Al-Taweel, Adil Ayub, Chyun-Yin Huang, Sadiq Rehmani, Adnan Al-Ayoubi, Faiz Y Bhora
Pneumopericardium resulting in cardiac tamponade in patients with lung cancer is not documented. We report a case of squamous cell carcinoma of the lung complicated by pneumopericardium and subsequent cardiac tamponade. The patient underwent an urgent pericardial window with rapid improvement in symptoms. We discuss the possible pathogenesis and treatment options for this rare condition.
December 2016: Thoracic and Cardiovascular Surgeon Reports
https://www.readbyqxmd.com/read/28017996/extraction-of-anthocyanins-from-pericarp-and-lipids-from-seeds-of-mangosteen-garcinia-mangostana-l-by-ultrasound-assisted-extraction-uae-and-evaluation-of-pericarp-extract-enriched-functional-ice-cream
#14
Lawan Hiranrangsee, Kishore K Kumaree, Muhammad Bilal Sadiq, Anil K Anal
Ultrasound-assisted extraction (UAE) was used to extract the anthocyanins from pericarp and lipids from the seeds of mangosteen. The optimum time for extraction of anthocyanin by maceration method and shaking water bath was 6 and 4 h, respectively, whereas, it was 5 min only for ultrasonic assisted extraction method. The anthocyanin content, extracted by UAE, was 23.54 mg Cyn-3-Glu/100 g. The regression equation derived by response surface methodology (RSM), was used to predict the anthocyanin content extracted by using UAE...
October 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28013200/quality-and-acceptability-of-measures-of-exercise-adherence-in-musculoskeletal-settings-a-systematic-review
#15
Sionnadh McLean, Melanie A Holden, Tanzila Potia, Melanie Gee, Ross Mallett, Sadiq Bhanbhro, Helen Parsons, Kirstie Haywood
OBJECTIVE: To recommend robust and relevant measures of exercise adherence for application in the musculoskeletal field. METHOD: A systematic review of measures was conducted in two phases. Phase 1 sought to identify all reproducible measures used to assess exercise adherence in a musculoskeletal setting. Phase 2 identified published evidence of measurement and practical properties of identified measures. Eight databases were searched (from inception to February 2016)...
December 24, 2016: Rheumatology
https://www.readbyqxmd.com/read/28011889/rare-case-of-losartan-induced-cough-complicated-by-rectus-sheath-haematoma-in-a-patient-on-rivaroxaban-therapy
#16
Goutham Talari, Preetham Talari, Joseph Sweigart, Sadiq Ahmed
Spontaneous rectus sheath haematomas and cough secondary to losartan are individually rare conditions. Abdominal wall haematomas present with abdominal pain and abdominal mass. Most patients are managed conservatively; Surgery or embolisation is indicated for shock, infection, rupture into the peritoneum or intractable pain. This is a man aged 65 years presented with dry cough and right-sided abdominal pain. He started losartan a few weeks prior to the onset of cough and had been on rivaroxaban for prior deep venous thrombosis...
December 23, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/28001084/resveratrol-as-an-anticancer-agent-a-review
#17
Abdur Rauf, Muhammad Imran, Masood Sadiq Butt, Muhammad Nadeem, Dennis G Peters, Mohammad S Mubarak
Owing to their antimicrobial, antioxidant, and anti-inflammatory activity, grapes (Vitis vinifera L.) are the archetypal paradigms of fruits used not only for nutritional purposes but also for exclusive therapeutics. Grapes are a prominent and promising source of phytochemicals, especially resveratrol, a phytoalexin antioxidant found in red grapes which has both chemopreventive and therapeutic effects against various ailments. Resveratrol's role in reducing different human cancers, including breast, cervical, uterine, blood, kidney, liver, eye, bladder, thyroid, esophageal, prostate, brain, lung, skin, gastric, colon, head and neck, bone, ovarian, and cervical, has been reviewed...
December 21, 2016: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/27983955/reconstruction-of-anterior-tracheal-defects%C3%A2-using-a-bioengineered-graft-in-a%C3%A2-porcine-model
#18
Adnan M Al-Ayoubi, Sadiq S Rehmani, Catherine F Sinclair, Robert S Lebovics, Faiz Y Bhora
BACKGROUND: Reconstruction of long-segment tracheal defects can be challenging and a suitable tracheal substitute remains lacking. We sought to create a bioengineered tracheal graft to repair such lesions using acellullar bovine dermis extracellular matrix (ECM) and male human mesenchymal stem cells (hMSCs) and implant it in a porcine model. METHODS: hMSCs were seeded on the ECM and incubated for 1 week with chondrogenic factors. An anterior 4 cm × 3 cm defect was surgically created in the trachea of 4-week-old female Yorkshire pigs...
February 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27936147/absence-of-association-between-behavior-problems-in-childhood-and-hypertension-in-midlife
#19
Sadiq M Saad, Gurch Randhawa, Dong Pang
BACKGROUND: It is known that behavior in childhood is associated with certain physical and mental health problems in midlife. However, there is limited evidence on the role of childhood behavior problems in the development of hypertension in adulthood. The present study aimed to examine whether behavior problems in childhood influenced the risk of hypertension in midlife in the United Kingdom 1958 birth cohort. METHODS: The 1958 British birth cohort comprised 17,638 individuals born in the first week of March 1958 in the United Kingdom...
2016: PloS One
https://www.readbyqxmd.com/read/27924252/how-to-conduct-a-systematic-review-a-narrative-literature-review
#20
REVIEW
Nusrat Jahan, Sadiq Naveed, Muhammad Zeshan, Muhammad A Tahir
Systematic reviews are ranked very high in research and are considered the most valid form of medical evidence. They provide a complete summary of the current literature relevant to a research question and can be of immense use to medical professionals. Our goal with this paper is to conduct a narrative review of the literature about systematic reviews and outline the essential elements of a systematic review along with the limitations of such a review.
November 4, 2016: Curēus
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