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https://www.readbyqxmd.com/read/27929656/epilogue-to-the-special-issue-on-co-occurrence-of-substance-use-and-tobacco
#1
Steven A Schroeder
This paper summarizes The American Journal of Drug and Alcohol Abuse special issue and offers suggestions for future steps. People who use alcohol or other addictive substances are much more likely to use tobacco. Yet, clinicians and scientists have long regarded these addiction categories as separate and unrelated. The resultant benign neglect of tobacco use has had disastrous consequences on patients. This special issue is an important step toward remedying that situation. It has reviewed what is known and what more needs to be discovered regarding the co-occurrence of tobacco use disorder (TUD) and other substance use disorders (SUDs)...
December 8, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27928715/the-impaired-anesthesiologist-what-you-should-know-about-substance-abuse
#2
Stefan T Samuelson, Ethan O Bryson
PURPOSE: Despite our considerable experience with the problem of addiction in our specialty, most anesthesia care providers don't know how to identify or help an impaired colleague. The purpose of this article to provide sufficient information on substance use disorder (SUD) to aid in its identification amongst colleagues and to assist in its management. PRINCIPAL FINDINGS: Depending on the region, 10-15% of the general population is prone to developing a SUD and will abuse drugs or alcohol at some point in their life...
December 7, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27922639/mesolimbic-leptin-signaling-negatively-regulates-cocaine-conditioned-reward
#3
M Shen, C Jiang, P Liu, F Wang, L Ma
The regulatory mechanisms underlying the response to addictive drugs are complex, and increasing evidence indicates that there is a role for appetite-regulating pathways in substance abuse. Leptin, an important adipose hormone that regulates energy balance and appetite, exerts its physiological functions via leptin receptors. However, the role of leptin signaling in regulating the response to cocaine remains unclear. Here we examined the potential role of leptin signaling in cocaine reward using a conditioned place preference (CPP) procedure...
December 6, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27909988/predicting-the-abuse-liability-of-entactogen-class-new-and-emerging-psychoactive-substances-via-preclinical-models-of-drug-self-administration
#4
Shawn M Aarde, Michael A Taffe
Animal models of drug self-administration are currently the gold standard for making predictions regarding the relative likelihood that a recreational drug substance will lead to continued use and addiction. Such models have been found to have high predictive accuracy and discriminative validity for a number of drug classes including ethanol, nicotine, opioids, and psychostimulants such as cocaine and methamphetamine. Members of the entactogen class of psychostimulants (drugs that produce an "open mind state" including feelings of interpersonal closeness, intimacy and empathy) have been less frequently studied in self-administration models...
December 2, 2016: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/27906413/comparison-of-psychodrug-prescription-patterns-in-patients-diagnosed-with-bipolar-disorder-and-addiction
#5
Diego Barral, Fátima Barral, Nuria Cruz, Juan D Molina, Victoria Sánchez, Teresa Rosique
OBJECTIVE: To describe if there are differences in the prescription of psychodrug at discharge between bipolar disorder patients with or without addiction. METHODS: We review all the psychotropic drugs dispensed to inpatients of a brief hospitalization psychiatric unit diagnosed as having bipolar disorder at time of discharge. We recluted 225 patients over 18 years old on their last manic episode, between the year 2000 and 2010. We classify them according to the comorbid presence or not of a substance abuse or dependence disorder...
November 2016: Actas Españolas de Psiquiatría
https://www.readbyqxmd.com/read/27901585/a-review-of-positron-emission-tomography-studies-exploring-the-dopaminergic-system-in-substance-use-with-a-focus-on-tobacco-as-a-co-variate
#6
Thulasi Thiruchselvam, Saima Malik, Bernard Le Foll
With the evolving sensitivity of positron emission tomography (PET) and the emergence of novel radiotracers, greater insight has been gained into the dopaminergic system as it relates to substance use. In this review, we summarize PET investigations from the last ten years that explore the dopaminergic system in tobacco, alcohol, stimulant, opiates, and cannabis addiction. In light of the prevalence of substance co-use, this review will also explore the effect of tobacco and other substance abuse co-morbidity on the dopaminergic system across study samples in the reviewed literature...
November 30, 2016: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/27899120/violence-narratives-of-mexican-women-treated-in-mutual-aid-residential-centers-for-addiction-treatment
#7
Ignacio Lozano-Verduzco, Martha Romero-Mendoza, Rodrigo Marín-Navarrete
BACKGROUND: Violence against women is a social and public health issue in Mexico. The aim of this article is to explore violence among an understudied group of women, who attended Mutual-Aid Residential Centers for Addiction Treatment and experienced stigma both as women and addicts. These centers are particular kind of addiction treatment services that stem from 12-step philosophy, but that have been found to manipulate said philosophy and exercise extreme forms of psychological and physical violence...
November 30, 2016: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/27891077/presynaptic-g-protein-coupled-receptors-gatekeepers-of-addiction
#8
REVIEW
Kari A Johnson, David M Lovinger
Drug abuse and addiction cause widespread social and public health problems, and the neurobiology underlying drug actions and drug use and abuse is an area of intensive research. Drugs of abuse alter synaptic transmission, and these actions contribute to acute intoxication as well as the chronic effects of abused substances. Transmission at most mammalian synapses involves neurotransmitter activation of two receptor subtypes, ligand-gated ion channels that mediate fast synaptic responses and G protein-coupled receptors (GPCRs) that have slower neuromodulatory actions...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27888955/emotion-dysregulation-mediates-between-childhood-emotional-abuse-and-motives-for-substance-use
#9
Usha Barahmand, Ali Khazaee, Goudarz Sadeghi Hashjin
The purpose of this study is to assess the relative mediating effects of impulsivity and emotion dysregulation in the relationship between childhood maltreatment and motives for opiate use. Seventy four adolescent users of Tramadol, a synthetic opiate, were recruited from a boot camp for de-addiction and rehabilitation services for the study. Data were collected between May, 2014 and November, 2014. Participants completed assessments of childhood abuse history, difficulties regulating emotions, impulsiveness and motives for substance use as well as a socio-demographic information sheet...
December 2016: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/27852970/-food-addiction-as-a-new-behavioral-addiction
#10
Erika Eördögh, Mária Hoyer, Gábor Szeleczky
: Aim of review: To overview the new studies on food addiction and highlighting the analogies and differences between food and drug addiction. RESULTS: Recent studies on food addiction have demonstrated that the neurobiological circuits involved in the development of drug addiction also play a role in food consumption, and that the uptake of nutrients by the organism is under the control of numerous complicated peripheral and central signal-transducing networks...
2016: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/27846654/-synthetic-drugs-an-overview-of-important-and-newly-emerging-substances
#11
F Betzler, A Heinz, S Köhler
Background: Synthetic drug use and abuse are on the rise. Governmental institutions report a shift in consumption from natural drugs to synthetic drugs, and show an increase in confiscation, particularly of methamphetamine and newly identified psychoactive substances. In addition, the media report an alarming increase in the rate of consumption and casualties resulting from the use of drugs such as "crystal meth" and warn against a flood of this and other designer drugs from eastern European countries. Objectives: The present article gives an overview of current popular and widely used synthetic drugs, both classical substances (amphetamine, methamphetamine, MDMA) and new psychoactive substances ("designer drugs", "legal highs")...
November 2016: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/27837404/the-biology-of-addiction
#12
Brent MacNicol
In this narrative review, the neurobiological mechanisms underlying substance abuse and addiction are discussed with a particular emphasis on the mechanisms that promote ongoing use and relapse. Addiction is estimated to affect 10-15% or more of the adult population, including physicians. Genetic predisposition, psychological and environmental risk factors, the timing of exposure to the substance, the type of substance used, and the frequency of use influence the individual's susceptibility to addiction. Abused substances act on the brain's reward system, a neural circuit that produces pleasurable feelings in response to stimuli that promote survival, thereby modifying future behavior to seek out similar stimuli...
November 11, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27833645/the-impact-of-psychopathological-subtypes-on-retention-rate-of-patients-with-substance-use-disorder-entering-residential-therapeutic-community-treatment
#13
Angelo G I Maremmani, Pier Paolo Pani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano, Icro Maremmani
BACKGROUND: A specific psychopathology of addiction has been proposed and described using the self-report symptom inventory (SCL-90), leading to a 5-factor aggregation of psychological/psychiatric symptoms: 'worthlessness and being trapped', 'somatic symptoms', 'sensitivity-psychoticism', 'panic-anxiety' and 'violence-suicide' in various populations of patients with heroin use disorder (HUD) and other substance use disorders (SUDs). These clusters of symptoms, according to studies that have highlighted the role of possible confounding factors (such as demographic and clinical characteristics, active heroin use, lifetime psychiatric problems and kind of treatment received by the patients), seem to constitute a trait rather than a state of the psychological structure of addiction...
2016: Annals of General Psychiatry
https://www.readbyqxmd.com/read/27832475/recovery-support-mediates-the-relationship-between-parental-warmth-and-quality-of-life-among-women-with-substance-use-disorders
#14
Suzanne Brown, Bryan Victor, Laurel M Hicks, Elizabeth M Tracy
PURPOSE: Historically, recovery from substance use disorders (SUD) has focused exclusively on the use or non-use of the addictive substance(s). More recently, SAMSHA [1] has defined recovery in a more holistic way, using quality of life (QoL) as a measure of recovery for individuals with substance use and mental health disorders. However, little is known about the myriad experiences that inform and affect QoL for individuals with substance use disorders. Using an attachment informed stress-buffering framework, the purpose of this study was to examine the contribution of parental warmth and recovery support to QoL among women in substance abuse treatment...
November 10, 2016: Quality of Life Research
https://www.readbyqxmd.com/read/27822187/cell-phone-addiction-a-review
#15
REVIEW
José De-Sola Gutiérrez, Fernando Rodríguez de Fonseca, Gabriel Rubio
We present a review of the studies that have been published about addiction to cell phones. We analyze the concept of cell-phone addiction as well as its prevalence, study methodologies, psychological features, and associated psychiatric comorbidities. Research in this field has generally evolved from a global view of the cell phone as a device to its analysis via applications and contents. The diversity of criteria and methodological approaches that have been used is notable, as is a certain lack of conceptual delimitation that has resulted in a broad spread of prevalent data...
2016: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/27822027/childhood-maltreatment-as-a-risk-factor-for-copd-findings-from-a-population-based-survey-of-canadian-adults
#16
Margot E Shields, Wendy E Hovdestad, Charles P Gilbert, Lil E Tonmyr
OBJECTIVE: The aim of this study was to examine the associations between childhood maltreatment (CM) and COPD in adulthood. METHODS: Data were from 15,902 respondents to the 2012 Canadian Community Health Survey - Mental Health. Multiple logistic regression models were used to examine associations between CM and COPD and the role of smoking and mental and substance use variables as mediators in associations. RESULTS: COPD in adulthood was related to CM, with associations differing by sex...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27813045/-health-medical-and-psychosocial-care-needs-of-older-drug-addicts-40-a-cross-sectional-study
#17
A Wehrwein, G Schröder, J Lindert
Background: We aimed 1) to assess health, health-related quality of life and social care needs of substance-abusing individuals aged 40+ and 2) to investigate associations between health and psychosocial care needs. Methods: We estimated the size of the population by using capture-recapture methods. Based on this sample size estimation, we conducted a cross-sectional survey with socio-demographic data, using standardized instruments including the SF-36 (36 items), a measure of physical disorders (14 items), social support, and psychosocial and health care needs and substance abuse ("European Addiction Severity Index")...
November 3, 2016: Das Gesundheitswesen
https://www.readbyqxmd.com/read/27805267/deficits-in-access-to-reward-are-associated-with-college-student-alcohol-use-disorder
#18
Keanan J Joyner, Alison M Pickover, Kathryn E Soltis, Ashley A Dennhardt, Matthew P Martens, James G Murphy
BACKGROUND: Reward deprivation has been implicated in major depressive disorder and severe substance abuse, but its potential relation to alcohol use disorder (AUD) symptoms in non-treatment-seeking young adult drinkers is less clear. Depression is often comorbid with alcohol misuse, so relations of AUD with reward deprivation might be due in part to the presence of depressive symptoms in young adults. Behavioral economic theory views addiction as a state that is related in part to deficits in drug-free rewards, and therefore requires an investigation into whether reward deprivation has a direct relation to alcohol misuse that is, at least partially, independent of mood...
December 2016: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/27803891/a-qualitative-study-of-the-relationship-between-methamphetamine-abuse-and-sexual-dysfunction-in-male-substance-abusers
#19
Behrouz Dolatshahi, Ali Farhoudian, Mozhgan Falahatdoost, Mahmoud Tavakoli, Ebrahim Rezaie Dogahe
BACKGROUND: Increased prevalent use of methamphetamine is a global public challenge. Information on drug use can be helpful in preventing high-risk behavior related to drug abuse. OBJECTIVES: This study aims to investigate the sexual function changes related to methamphetamine use in the male clients of public and private addiction treatment centers. PATIENTS AND METHODS: In this qualitative study, 45 men (35 methamphetamine users, 5 family members of the users, and 5 psychiatrists or physicians who were famous for treating or researching addiction) are involved...
September 2016: International Journal of High Risk Behaviors & Addiction
https://www.readbyqxmd.com/read/27802545/association-between-prescription-of-major-psychotropic-medications-and-violent-reoffending-after-prison-release
#20
Zheng Chang, Paul Lichtenstein, Niklas Långström, Henrik Larsson, Seena Fazel
Importance: Individuals released from prison have high rates of violent reoffending, and there is uncertainty about whether pharmacological treatments reduce reoffending risk. Objective: To investigate the associations between major classes of psychotropic medications and violent reoffending. Design, Setting, and Participants: This cohort study included all released prisoners in Sweden from July 1, 2005, to December 31, 2010, through linkage of population-based registers...
November 1, 2016: JAMA: the Journal of the American Medical Association
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