keyword
https://read.qxmd.com/read/38702807/severe-morbidity-and-hospital-based-mortality-from-rift-valley-fever-disease-between-november-2017-and-march-2020-among-humans-in-uganda
#1
JOURNAL ARTICLE
Zacchaeus Anywaine, Christian Hansen, George M Warimwe, Ggayi Abu-Baker Mustapher, Luke Nyakarahuka, Stephen Balinandi, Alex Riolexus Ario, Julius J Lutwama, Alison Elliott, Pontiano Kaleebu
BACKGROUND: Rift Valley fever (RVF) is a zoonotic viral disease of increasing intensity among humans in Africa and the Arabian Peninsula. In Uganda, cases reported prior to 2016 were mild or not fully documented. We report in this paper on the severe morbidity and hospital-based mortality of human cases in Uganda. METHODS: Between November 2017 and March 2020 human cases reported to the Uganda Virus Research Institute (UVRI) were confirmed by polymerase chain reaction (PCR)...
May 3, 2024: Virology Journal
https://read.qxmd.com/read/38702693/correction-assessing-real-world-gait-with%C3%A2-digital-technology-validation-insights-and%C3%A2-recommendations-from%C3%A2-the%C3%A2-mobilise-d-consortium
#2
M Encarna Micó-Amigo, Tecla Bonci, Anisoara Paraschiv-Ionescu, Martin Ullrich, Cameron Kirk, Abolfazl Soltani, Arne Küderle, Eran Gazit, Francesca Salis, Lisa Alcock, Kamiar Aminian, Clemens Becker, Stefano Bertuletti, Philip Brown, Ellen Buckley, Alma Cantu, Anne-Elie Carsin, Marco Caruso, Brian Caulfield, Andrea Cereatti, Lorenzo Chiari, Ilaria D'Ascanio, Bjoern Eskofier, Sara Fernstad, Marcel Froehlich, Judith Garcia-Aymerich, Clint Hansen, Jeffrey M Hausdorff, Hugo Hiden, Emily Hume, Alison Keogh, Felix Kluge, Sarah Koch, Walter Maetzler, Dimitrios Megaritis, Arne Mueller, Martijn Niessen, Luca Palmerini, Lars Schwickert, Kirsty Scott, Basil Sharrack, Henrik Sillén, David Singleton, Beatrix Vereijken, Ioannis Vogiatzis, Alison J Yarnall, Lynn Rochester, Claudia Mazzà, Silvia Del Din
No abstract text is available yet for this article.
May 3, 2024: Journal of Neuroengineering and Rehabilitation
https://read.qxmd.com/read/38702599/missingness-mechanisms-and-generalizability-of-patient-reported-outcome-measures-in-colorectal-cancer-survivors-assessing-the-reasonableness-of-the-missing-completely-at-random-assumption
#3
JOURNAL ARTICLE
Johanne Dam Lyhne, Allan 'Ben' Smith, Lars Henrik Jensen, Torben Frøstrup Hansen, Lisbeth Frostholm, Signe Timm
BACKGROUND: Patient-Reported Outcome Measures (PROM) provide important information, however, missing PROM data threaten the interpretability and generalizability of findings by introducing potential bias. This study aims to provide insight into missingness mechanisms and inform future researchers on generalizability and possible methodological solutions to overcome missing PROM data problems during data collection and statistical analyses. METHODS: We identified 10,236 colorectal cancer survivors (CRCs) above 18y, diagnosed between 2014 and 2018 through the Danish Clinical Registries...
May 3, 2024: BMC Medical Research Methodology
https://read.qxmd.com/read/38702385/discovery-of-the-first-hydrothermal-field-along-the-500-km-long-knipovich-ridge-offshore-svalbard-the-j%C3%A3-tul-field
#4
JOURNAL ARTICLE
Gerhard Bohrmann, Katharina Streuff, Miriam Römer, Stig-Morten Knutsen, Daniel Smrzka, Jan Kleint, Aaron Röhler, Thomas Pape, Nils Rune Sandstå, Charlotte Kleint, Christian Hansen, Christian Dos Santos Ferreira, Maren Walter, Gustavo Macedo de Paula Santos, Wolfgang Bach
Oceanic spreading centers north of Iceland are characterized by ultraslow spreading rates, and related hydrothermal activity has been detected in the water column and at the seafloor along nearly all ridge segments. An exception is the 500-km-long Knipovich Ridge, from where, until now, no hydrothermal vents were known. Here we report the investigation of the first hydrothermal vent field of the Knipovich Ridge, which was discovered in July 2022 during expedition MSM109. The newly discovered hydrothermal field, named Jøtul hydrothermal field, is associated with the eastern bounding fault of the rift valley rather than with an axial volcanic ridge...
May 3, 2024: Scientific Reports
https://read.qxmd.com/read/38702286/pharmacists-combating-antimicrobial-resistance-a-delphi-study-on-antibiotic-dispensing
#5
JOURNAL ARTICLE
Maarten Lambert, Anneloes Wonink, Ria Benko, Malene Plejdrup Hansen, Liset van Dijk, Katja Taxis
BACKGROUND: The daily work of community pharmacists includes dispensing antibiotics, but little is known about how this should be done to ensure quality use of antibiotics. OBJECTIVE: To define specific tasks of the community pharmacist when dispensing antibiotics and to assess to what extent these tasks can be implemented in practice in Europe. METHODS: A Delphi study with community pharmacist experts in the European Economic Area. Statements on potential tasks for pharmacists during the antibiotic dispensing process were based on a systematic literature review...
April 16, 2024: Research in Social & Administrative Pharmacy: RSAP
https://read.qxmd.com/read/38702285/ultrafast-3-d-transcutaneous-super-resolution-ultrasound-using-row-column-array-specific-coherence-based-beamforming-and-rolling-acoustic-sub-aperture-processing-in-vitro-in-rabbit-and-in-human-study
#6
JOURNAL ARTICLE
Joseph Hansen-Shearer, Jipeng Yan, Marcelo Lerendegui, Biao Huang, Matthieu Toulemonde, Kai Riemer, Qingyuan Tan, Johanna Tonko, Peter D Weinberg, Chris Dunsby, Meng-Xing Tang
OBJECTIVE: This study aimed to realise 3-D super-resolution ultrasound imaging transcutaneously with a row-column array which has far fewer independent electronic channels and a wider field of view than typical fully addressed 2-D matrix arrays. The in vivo image quality of the row-column array is generally poor, particularly when imaging non-invasively. This study aimed to develop a suite of image formation and post-processing methods to improve image quality and demonstrate the feasibility of ultrasound localisation microscopy using a row-column array, transcutaneously on a rabbit model and in a human...
May 2, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38702196/neuron-specific-chromatin-disruption-at-cpg-islands-and-aging-related-regions-in-kabuki-syndrome-mice
#7
JOURNAL ARTICLE
Leandros Boukas, Teresa Romeo Luperchio, Afrooz Razi, Kasper D Hansen, Hans T Bjornsson
Many Mendelian developmental disorders caused by coding variants in epigenetic regulators have now been discovered. Epigenetic regulators are broadly expressed, and each of these disorders typically exhibits phenotypic manifestations from many different organ systems. An open question is whether the chromatin disruption - the root of the pathogenesis - is similar in the different disease-relevant cell types. This is possible in principle, since all these cell types are subject to effects from the same causative gene, that has the same kind of function (e...
May 3, 2024: Genome Research
https://read.qxmd.com/read/38701770/sensor-macrophages-derived-from-human-induced-pluripotent-stem-cells-to-assess-pyrogenic-contaminations-in-parenteral-drugs
#8
JOURNAL ARTICLE
Shifaa Abdin, Friederike Mansel, Anna Hashtchin, Mania Ackermann, Gesine Hansen, Bjoern Becker, Benjamin Kick, Nhi Pham, Hendrik Dietz, Christoph Schaniel, Ulrich Martin, Ingo Spreitzer, Nico Lachmann
Ensuring the safety of parenteral drugs before injection into patients is of utmost importance. New regulations around the globe and the need to refrain from using animals however, have highlighted the need for new cell sources to be used in next-generation bioassays to detect the entire spectrum of possible contaminating pyrogens. Given the current drawbacks of the Monocyte-Activation-Test (MAT) with respect to the use of primary peripheral blood mono-nuclear cells (PBMCs) or the use of monocytic cell lines, we here demonstrate the manufacturing of sensor monocyte/macrophages from human induced pluripotent stem cells (iMonoMac), which are fully defined and superior to current cell products...
May 3, 2024: Biofabrication
https://read.qxmd.com/read/38701750/enzyme-engineering-lets-us-play-with-new-building-blocks-in-non-ribosomal-peptide-synthesis
#9
JOURNAL ARTICLE
Minuri S Ratnayake, Mathias H Hansen, Max J Cryle
In a recent issue of Nature Chemical Biology, Folger et al. demonstrated a high-throughput approach for engineering peptide bond forming domains from non-ribosomal peptide synthesis. A non-ribosomal peptide synthetase module from surfactin biosynthesis was reprogrammed to accept a fatty acid substrate into peptide biosynthesis, thus illustrating the potential of this approach for generating novel bioactive peptides.
May 2, 2024: Structure
https://read.qxmd.com/read/38701745/association-between-telomere-length-and-plasmodium-falciparum-malaria-endemicity-in-sub-saharan-africans
#10
JOURNAL ARTICLE
Michael A McQuillan, Simon Verhulst, Matthew E B Hansen, William Beggs, Dawit Wolde Meskel, Gurja Belay, Thomas Nyambo, Sununguko Wata Mpoloka, Gaonyadiwe George Mokone, Charles Fokunang, Alfred K Njamnshi, Stephen J Chanock, Abraham Aviv, Sarah A Tishkoff
Leukocyte telomere length (LTL) varies significantly across human populations, with individuals of African ancestry having longer LTL than non-Africans. However, the genetic and environmental drivers of LTL variation in Africans remain largely unknown. We report here on the relationship between LTL, genetics, and a variety of environmental and climatic factors in ethnically diverse African adults (n = 1,818) originating from Botswana, Tanzania, Ethiopia, and Cameroon. We observe significant variation in LTL among populations, finding that the San hunter-gatherers from Botswana have the longest leukocyte telomeres and that the Fulani pastoralists from Cameroon have the shortest telomeres...
May 2, 2024: American Journal of Human Genetics
https://read.qxmd.com/read/38701469/novel-measurement-of-the-neutron-magnetic-form-factor-from-a-3-mirror-nuclei
#11
JOURNAL ARTICLE
S N Santiesteban, S Li, D Abrams, S Alsalmi, D Androic, K Aniol, J Arrington, T Averett, C Ayerbe Gayoso, J Bane, S Barcus, J Barrow, A Beck, V Bellini, H Bhatt, D Bhetuwal, D Biswas, A Camsonne, J Castellanos, J Chen, J-P Chen, D Chrisman, M E Christy, C Clarke, S Covrig, R Cruz-Torres, D Day, D Dutta, E Fuchey, C Gal, F Garibaldi, T N Gautam, T Gogami, J Gomez, P Guèye, T J Hague, J O Hansen, F Hauenstein, W Henry, D W Higinbotham, R J Holt, C Hyde, K Itabashi, M Kaneta, A Karki, A T Katramatou, C E Keppel, P M King, L Kurbany, T Kutz, N Lashley-Colthirst, W B Li, H Liu, N Liyanage, E Long, A Lovato, J Mammei, P Markowitz, R E McClellan, F Meddi, D Meekins, R Michaels, M Mihovilovič, A Moyer, S Nagao, D Nguyen, M Nycz, M Olson, L Ou, V Owen, C Palatchi, B Pandey, A Papadopoulou, S Park, T Petkovic, S Premathilake, V Punjabi, R D Ransome, P E Reimer, J Reinhold, S Riordan, N Rocco, V M Rodriguez, A Schmidt, B Schmookler, E P Segarra, A Shahinyan, S Širca, K Slifer, P Solvignon, T Su, R Suleiman, L Tang, Y Tian, W Tireman, F Tortorici, Y Toyama, K Uehara, G M Urciuoli, D Votaw, J Williamson, B Wojtsekhowski, S Wood, Z H Ye, J Zhang, X Zheng
The electromagnetic form factors of the proton and neutron encode information on the spatial structure of their charge and magnetization distributions. While measurements of the proton are relatively straightforward, the lack of a free neutron target makes measurements of the neutron's electromagnetic structure more challenging and more sensitive to experimental or model-dependent uncertainties. Various experiments have attempted to extract the neutron form factors from scattering from the neutron in deuterium, with different techniques providing different, and sometimes large, systematic uncertainties...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701458/first-measurement-of-the-t-dependence-of-incoherent-j-%C3%AF-photonuclear-production
#12
JOURNAL ARTICLE
S Acharya, D Adamová, A Adler, G Aglieri Rinella, M Agnello, N Agrawal, Z Ahammed, S Ahmad, S U Ahn, I Ahuja, A Akindinov, M Al-Turany, D Aleksandrov, B Alessandro, H M Alfanda, R Alfaro Molina, B Ali, A Alici, N Alizadehvandchali, A Alkin, J Alme, G Alocco, T Alt, A R Altamura, I Altsybeev, J R Alvarado, M N Anaam, C Andrei, A Andronic, V Anguelov, F Antinori, P Antonioli, N Apadula, L Aphecetche, H Appelshäuser, C Arata, S Arcelli, M Aresti, R Arnaldi, J G M C A Arneiro, I C Arsene, M Arslandok, A Augustinus, R Averbeck, M D Azmi, H Baba, A Badalà, J Bae, Y W Baek, X Bai, R Bailhache, Y Bailung, A Balbino, A Baldisseri, B Balis, D Banerjee, Z Banoo, R Barbera, F Barile, L Barioglio, M Barlou, G G Barnaföldi, L S Barnby, V Barret, L Barreto, C Bartels, K Barth, E Bartsch, N Bastid, S Basu, G Batigne, D Battistini, B Batyunya, D Bauri, J L Bazo Alba, I G Bearden, C Beattie, P Becht, D Behera, I Belikov, A D C Bell Hechavarria, F Bellini, R Bellwied, S Belokurova, G Bencedi, S Beole, A Bercuci, Y Berdnikov, A Berdnikova, L Bergmann, M G Besoiu, L Betev, P P Bhaduri, A Bhasin, M A Bhat, B Bhattacharjee, L Bianchi, N Bianchi, J Bielčík, J Bielčíková, J Biernat, A P Bigot, A Bilandzic, G Biro, S Biswas, N Bize, J T Blair, D Blau, M B Blidaru, N Bluhme, C Blume, G Boca, F Bock, T Bodova, A Bogdanov, S Boi, J Bok, L Boldizsár, M Bombara, P M Bond, G Bonomi, H Borel, A Borissov, A G Borquez Carcamo, H Bossi, E Botta, Y E M Bouziani, L Bratrud, P Braun-Munzinger, M Bregant, M Broz, G E Bruno, M D Buckland, D Budnikov, H Buesching, S Bufalino, P Buhler, N Burmasov, Z Buthelezi, A Bylinkin, S A Bysiak, M Cai, H Caines, A Caliva, E Calvo Villar, J M M Camacho, P Camerini, F D M Canedo, S L Cantway, M Carabas, A A Carballo, F Carnesecchi, R Caron, L A D Carvalho, J Castillo Castellanos, F Catalano, C Ceballos Sanchez, I Chakaberia, P Chakraborty, S Chandra, S Chapeland, M Chartier, S Chattopadhyay, S Chattopadhyay, T Cheng, C Cheshkov, B Cheynis, V Chibante Barroso, D D Chinellato, E S Chizzali, J Cho, S Cho, P Chochula, P Christakoglou, C H Christensen, P Christiansen, T Chujo, M Ciacco, C Cicalo, F Cindolo, M R Ciupek, G Clai, F Colamaria, J S Colburn, D Colella, M Colocci, M Concas, G Conesa Balbastre, Z Conesa Del Valle, G Contin, J G Contreras, M L Coquet, P Cortese, M R Cosentino, F Costa, S Costanza, C Cot, J Crkovská, P Crochet, R Cruz-Torres, P Cui, A Dainese, M C Danisch, A Danu, P Das, P Das, S Das, A R Dash, S Dash, A De Caro, G de Cataldo, J de Cuveland, A De Falco, D De Gruttola, N De Marco, C De Martin, S De Pasquale, R Deb, S Deb, R Del Grande, L Dello Stritto, W Deng, P Dhankher, D Di Bari, A Di Mauro, B Diab, R A Diaz, T Dietel, Y Ding, R Divià, D U Dixit, Ø Djuvsland, U Dmitrieva, A Dobrin, B Dönigus, J M Dubinski, A Dubla, S Dudi, P Dupieux, M Durkac, N Dzalaiova, T M Eder, R J Ehlers, F Eisenhut, R Ejima, D Elia, B Erazmus, F Ercolessi, F Erhardt, M R Ersdal, B Espagnon, G Eulisse, D Evans, S Evdokimov, L Fabbietti, M Faggin, J Faivre, F Fan, W Fan, A Fantoni, M Fasel, P Fecchio, A Feliciello, G Feofilov, A Fernández Téllez, L Ferrandi, M B Ferrer, A Ferrero, C Ferrero, A Ferretti, V J G Feuillard, V Filova, D Finogeev, F M Fionda, F Flor, A N Flores, S Foertsch, I Fokin, S Fokin, E Fragiacomo, E Frajna, U Fuchs, N Funicello, C Furget, A Furs, T Fusayasu, J J Gaardhøje, M Gagliardi, A M Gago, T Gahlaut, C D Galvan, D R Gangadharan, P Ganoti, C Garabatos, A T Garcia, T García Chávez, E Garcia-Solis, C Gargiulo, K Garner, P Gasik, A Gautam, M B Gay Ducati, M Germain, A Ghimouz, C Ghosh, M Giacalone, P Giubellino, P Giubilato, A M C Glaenzer, P Glässel, E Glimos, D J Q Goh, V Gonzalez, M Gorgon, K Goswami, S Gotovac, V Grabski, L K Graczykowski, E Grecka, A Grelli, C Grigoras, V Grigoriev, S Grigoryan, F Grosa, J F Grosse-Oetringhaus, R Grosso, D Grund, G G Guardiano, R Guernane, M Guilbaud, K Gulbrandsen, T Gündem, T Gunji, W Guo, A Gupta, R Gupta, R Gupta, K Gwizdziel, L Gyulai, M K Habib, C Hadjidakis, F U Haider, H Hamagaki, A Hamdi, M Hamid, Y Han, B G Hanley, R Hannigan, J Hansen, M R Haque, J W Harris, A Harton, H Hassan, D Hatzifotiadou, P Hauer, L B Havener, S T Heckel, E Hellbär, H Helstrup, M Hemmer, T Herman, G Herrera Corral, F Herrmann, S Herrmann, K F Hetland, B Heybeck, H Hillemanns, B Hippolyte, F W Hoffmann, B Hofman, B Hohlweger, G H Hong, M Horst, A Horzyk, Y Hou, P Hristov, C Hughes, P Huhn, L M Huhta, T J Humanic, A Hutson, D Hutter, R Ilkaev, H Ilyas, M Inaba, G M Innocenti, M Ippolitov, A Isakov, T Isidori, M S Islam, M Ivanov, M Ivanov, V Ivanov, K E Iversen, M Jablonski, B Jacak, N Jacazio, P M Jacobs, S Jadlovska, J Jadlovsky, S Jaelani, C Jahnke, M J Jakubowska, M A Janik, T Janson, M Jercic, S Ji, S Jia, A A P Jimenez, F Jonas, D M Jones, J M Jowett, J Jung, M Jung, A Junique, A Jusko, M J Kabus, J Kaewjai, P Kalinak, A S Kalteyer, A Kalweit, V Kaplin, A Karasu Uysal, D Karatovic, O Karavichev, T Karavicheva, P Karczmarczyk, E Karpechev, U Kebschull, R Keidel, D L D Keijdener, M Keil, B Ketzer, S S Khade, A M Khan, S Khan, A Khanzadeev, Y Kharlov, A Khatun, A Khuntia, M B Kidson, B Kileng, B Kim, C Kim, D J Kim, E J Kim, J Kim, J S Kim, J Kim, J Kim, M Kim, S Kim, T Kim, K Kimura, S Kirsch, I Kisel, S Kiselev, A Kisiel, J P Kitowski, J L Klay, J Klein, S Klein, C Klein-Bösing, M Kleiner, T Klemenz, A Kluge, A G Knospe, C Kobdaj, T Kollegger, A Kondratyev, N Kondratyeva, E Kondratyuk, J Konig, S A Konigstorfer, P J Konopka, G Kornakov, M Korwieser, S D Koryciak, A Kotliarov, V Kovalenko, M Kowalski, V Kozhuharov, I Králik, A Kravčáková, L Krcal, M Krivda, F Krizek, K Krizkova Gajdosova, M Kroesen, M Krüger, D M Krupova, E Kryshen, V Kučera, C Kuhn, P G Kuijer, T Kumaoka, D Kumar, L Kumar, N Kumar, S Kumar, S Kundu, P Kurashvili, A Kurepin, A B Kurepin, A Kuryakin, S Kushpil, M J Kweon, Y Kwon, S L La Pointe, P La Rocca, A Lakrathok, M Lamanna, A R Landou, R Langoy, P Larionov, E Laudi, L Lautner, R Lavicka, R Lea, H Lee, I Legrand, G Legras, J Lehrbach, T M Lelek, R C Lemmon, I León Monzón, M M Lesch, E D Lesser, P Lévai, X Li, X L Li, J Lien, R Lietava, I Likmeta, B Lim, S H Lim, V Lindenstruth, A Lindner, C Lippmann, A Liu, D H Liu, J Liu, G S S Liveraro, I M Lofnes, C Loizides, S Lokos, J Lomker, P Loncar, J A Lopez, X Lopez, E López Torres, P Lu, J R Luhder, M Lunardon, G Luparello, Y G Ma, M Mager, A Maire, E M Majerz, M V Makariev, M Malaev, G Malfattore, N M Malik, Q W Malik, S K Malik, L Malinina, D Mallick, N Mallick, G Mandaglio, S K Mandal, V Manko, F Manso, V Manzari, Y Mao, R W Marcjan, G V Margagliotti, A Margotti, A Marín, C Markert, P Martinengo, M I Martínez, G Martínez García, M P P Martins, S Masciocchi, M Masera, A Masoni, L Massacrier, A Mastroserio, O Matonoha, S Mattiazzo, P F T Matuoka, A Matyja, C Mayer, A L Mazuecos, F Mazzaschi, M Mazzilli, J E Mdhluli, A F Mechler, Y Melikyan, A Menchaca-Rocha, E Meninno, A S Menon, M Meres, S Mhlanga, Y Miake, L Micheletti, L C Migliorin, D L Mihaylov, K Mikhaylov, A N Mishra, D Miśkowiec, A Modak, A P Mohanty, B Mohanty, M Mohisin Khan, M A Molander, S Monira, Z Moravcova, C Mordasini, D A Moreira De Godoy, I Morozov, A Morsch, T Mrnjavac, V Muccifora, S Muhuri, J D Mulligan, A Mulliri, M G Munhoz, R H Munzer, H Murakami, S Murray, L Musa, J Musinsky, J W Myrcha, B Naik, A I Nambrath, B K Nandi, R Nania, E Nappi, A F Nassirpour, A Nath, C Nattrass, M N Naydenov, A Neagu, A Negru, L Nellen, R Nepeivoda, S Nese, G Neskovic, B S Nielsen, E G Nielsen, S Nikolaev, S Nikulin, V Nikulin, F Noferini, S Noh, P Nomokonov, J Norman, N Novitzky, P Nowakowski, A Nyanin, J Nystrand, M Ogino, S Oh, A Ohlson, V A Okorokov, J Oleniacz, A C Oliveira Da Silva, M H Oliver, A Onnerstad, C Oppedisano, A Ortiz Velasquez, J Otwinowski, M Oya, K Oyama, Y Pachmayer, S Padhan, D Pagano, G Paić, S Paisano-Guzmán, A Palasciano, S Panebianco, H Park, H Park, J Park, J E Parkkila, Y Patley, R N Patra, B Paul, H Pei, T Peitzmann, X Peng, M Pennisi, D Peresunko, G M Perez, Y Pestov, V Petrov, M Petrovici, R P Pezzi, S Piano, M Pikna, P Pillot, O Pinazza, L Pinsky, C Pinto, S Pisano, M Płoskoń, M Planinic, F Pliquett, M G Poghosyan, B Polichtchouk, S Politano, N Poljak, A Pop, S Porteboeuf-Houssais, V Pozdniakov, I Y Pozos, K K Pradhan, S K Prasad, S Prasad, R Preghenella, F Prino, C A Pruneau, I Pshenichnov, M Puccio, S Pucillo, Z Pugelova, S Qiu, L Quaglia, R E Quishpe, S Ragoni, A Rakotozafindrabe, L Ramello, F Rami, T A Rancien, M Rasa, S S Räsänen, R Rath, M P Rauch, I Ravasenga, K F Read, C Reckziegel, A R Redelbach, K Redlich, C A Reetz, H D Regules-Medel, A Rehman, F Reidt, H A Reme-Ness, Z Rescakova, K Reygers, A Riabov, V Riabov, R Ricci, M Richter, A A Riedel, W Riegler, C Ristea, M V Rodriguez, M Rodríguez Cahuantzi, S A Rodríguez Ramírez, K Røed, R Rogalev, E Rogochaya, T S Rogoschinski, D Rohr, D Röhrich, P F Rojas, S Rojas Torres, P S Rokita, G Romanenko, F Ronchetti, A Rosano, E D Rosas, K Roslon, A Rossi, A Roy, S Roy, N Rubini, D Ruggiano, R Rui, P G Russek, R Russo, A Rustamov, E Ryabinkin, Y Ryabov, A Rybicki, H Rytkonen, J Ryu, W Rzesa, O A M Saarimaki, R Sadek, S Sadhu, S Sadovsky, J Saetre, K Šafařík, P Saha, S K Saha, S Saha, B Sahoo, B Sahoo, R Sahoo, S Sahoo, D Sahu, P K Sahu, J Saini, K Sajdakova, S Sakai, M P Salvan, S Sambyal, I Sanna, T B Saramela, D Sarkar, N Sarkar, P Sarma, V Sarritzu, V M Sarti, M H P Sas, J Schambach, H S Scheid, C Schiaua, R Schicker, A Schmah, C Schmidt, H R Schmidt, M O Schmidt, M Schmidt, N V Schmidt, A R Schmier, R Schotter, A Schröter, J Schukraft, K Schweda, G Scioli, E Scomparin, J E Seger, Y Sekiguchi, D Sekihata, M Selina, I Selyuzhenkov, S Senyukov, J J Seo, D Serebryakov, L Šerkšnytė, A Sevcenco, T J Shaba, A Shabetai, R Shahoyan, A Shangaraev, A Sharma, B Sharma, D Sharma, H Sharma, M Sharma, S Sharma, S Sharma, U Sharma, A Shatat, O Sheibani, K Shigaki, M Shimomura, J Shin, S Shirinkin, Q Shou, Y Sibiriak, S Siddhanta, T Siemiarczuk, T F Silva, D Silvermyr, T Simantathammakul, R Simeonov, B Singh, B Singh, K Singh, R Singh, R Singh, R Singh, S Singh, V K Singh, V Singhal, T Sinha, B Sitar, M Sitta, T B Skaali, G Skorodumovs, M Slupecki, N Smirnov, R J M Snellings, E H Solheim, J Song, A Songmoolnak, C Sonnabend, F Soramel, A B Soto-Hernandez, R Spijkers, I Sputowska, J Staa, J Stachel, I Stan, P J Steffanic, S F Stiefelmaier, D Stocco, I Storehaug, P Stratmann, S Strazzi, C P Stylianidis, A A P Suaide, C Suire, M Sukhanov, M Suljic, R Sultanov, V Sumberia, S Sumowidagdo, S Swain, I Szarka, M Szymkowski, S F Taghavi, G Taillepied, J Takahashi, G J Tambave, S Tang, Z Tang, J D Tapia Takaki, N Tapus, L A Tarasovicova, M G Tarzila, G F Tassielli, A Tauro, G Tejeda Muñoz, A Telesca, L Terlizzi, C Terrevoli, S Thakur, D Thomas, A Tikhonov, A R Timmins, M Tkacik, T Tkacik, A Toia, R Tokumoto, K Tomohiro, N Topilskaya, M Toppi, T Tork, V V Torres, A G Torres Ramos, A Trifiró, A S Triolo, S Tripathy, T Tripathy, S Trogolo, V Trubnikov, W H Trzaska, T P Trzcinski, A Tumkin, R Turrisi, T S Tveter, K Ullaland, B Ulukutlu, A Uras, M Urioni, G L Usai, M Vala, N Valle, L V R van Doremalen, M van Leeuwen, C A van Veen, R J G van Weelden, P Vande Vyvre, D Varga, Z Varga, M Vasileiou, A Vasiliev, O Vázquez Doce, O Vazquez Rueda, V Vechernin, E Vercellin, S Vergara Limón, R Verma, L Vermunt, R Vértesi, M Verweij, L Vickovic, Z Vilakazi, O Villalobos Baillie, A Villani, G Vino, A Vinogradov, T Virgili, M M O Virta, V Vislavicius, A Vodopyanov, B Volkel, M A Völkl, K Voloshin, S A Voloshin, G Volpe, B von Haller, I Vorobyev, N Vozniuk, J Vrláková, J Wan, C Wang, D Wang, Y Wang, Y Wang, A Wegrzynek, F T Weiglhofer, S C Wenzel, J P Wessels, J Wiechula, J Wikne, G Wilk, J Wilkinson, G A Willems, B Windelband, M Winn, J R Wright, W Wu, Y Wu, R Xu, A Yadav, A K Yadav, S Yalcin, Y Yamaguchi, S Yang, S Yano, Z Yin, I-K Yoo, J H Yoon, H Yu, S Yuan, A Yuncu, V Zaccolo, C Zampolli, F Zanone, N Zardoshti, A Zarochentsev, P Závada, N Zaviyalov, M Zhalov, B Zhang, C Zhang, L Zhang, S Zhang, X Zhang, Y Zhang, Z Zhang, M Zhao, V Zherebchevskii, Y Zhi, D Zhou, Y Zhou, J Zhu, Y Zhu, S C Zugravel, N Zurlo
The first measurement of the cross section for incoherent photonuclear production of J/ψ vector mesons as a function of the Mandelstam |t| variable is presented. The measurement was carried out with the ALICE detector at midrapidity, |y|<0.8, using ultraperipheral collisions of Pb nuclei at a center-of-mass energy per nucleon pair of sqrt[s_{NN}]=5.02  TeV. This rapidity interval corresponds to a Bjorken-x range (0.3-1.4)×10^{-3}. Cross sections are given in five |t| intervals in the range 0...
April 19, 2024: Physical Review Letters
https://read.qxmd.com/read/38701099/a-systematic-analysis-of-regression-models-for-protein-engineering
#13
JOURNAL ARTICLE
Richard Michael, Jacob Kæstel-Hansen, Peter Mørch Groth, Simon Bartels, Jesper Salomon, Pengfei Tian, Nikos S Hatzakis, Wouter Boomsma
To optimize proteins for particular traits holds great promise for industrial and pharmaceutical purposes. Machine Learning is increasingly applied in this field to predict properties of proteins, thereby guiding the experimental optimization process. A natural question is: How much progress are we making with such predictions, and how important is the choice of regressor and representation? In this paper, we demonstrate that different assessment criteria for regressor performance can lead to dramatically different conclusions, depending on the choice of metric, and how one defines generalization...
May 3, 2024: PLoS Computational Biology
https://read.qxmd.com/read/38698699/the-first-decade-of-the-danish-palliative-care-database-improvements-and-ongoing-challenges-in-the-quality-and-use-of-specialised-palliative-care
#14
JOURNAL ARTICLE
Mathilde Adsersen, Maiken Bang Hansen, Mette Asbjoern Neergaard, Per Sjøgren, Mai-Britt Guldin, Mogens Groenvold
BACKGROUND: Danish Palliative Care Database comprises five quality indicators: (1) Contact with specialised palliative care (SPC) among referred patients, (2) Waiting time of less than 10 days, (3) Proportion of patients who died from (A) cancer or (B) non-cancer diseases, and had contact with SPC, (4) Proportion of patients completing the patient-reported outcome measure at baseline (EORTC QLQ-C15-PAL), and (5) Proportion of patients discussed at a multidisciplinary conference. PURPOSE: To investigate changes in the quality indicators from 2010 until 2020 in cancer and non-cancer patients...
May 2, 2024: Acta Oncologica
https://read.qxmd.com/read/38698471/the-effect-of-focused-lung-ultrasonography-on-antibiotic-prescribing-in-patients-with-acute-lower-respiratory-tract-infections-in-danish-general-practice-study-protocol-for-a-pragmatic-randomized-controlled-trial-plus-flus
#15
JOURNAL ARTICLE
Julie Jepsen Strøm, Camilla Aakjær Andersen, Martin Bach Jensen, Janus Laust Thomsen, Christian B Laursen, Søren Helbo Skaarup, Hans Henrik Lawaetz Schultz, Malene Plejdrup Hansen
BACKGROUND: The use of antibiotics is a key driver of antimicrobial resistance and is considered a major threat to global health. In Denmark, approximately 75% of antibiotic prescriptions are issued in general practice, with acute lower respiratory tract infections (LRTIs) being one of the most common indications. Adults who present to general practice with symptoms of acute LRTI often suffer from self-limiting viral infections. However, some patients have bacterial community-acquired pneumonia (CAP), a potential life-threatening infection, that requires immediate antibiotic treatment...
May 2, 2024: Trials
https://read.qxmd.com/read/38698317/moving-together-benefits-of-an-online-dance-program-on-physical-and-mental-health-for-older-women-an-exploratory-mixed-method-study
#16
JOURNAL ARTICLE
Rasmus Kopp Hansen, Elizabeth Jochum, Ditte Egholm, Morten Villumsen, Rogerio Pessoto Hirata
BACKGROUND: Previous studies show that in-person dance training is a beneficial form of physical activity that involves mental, social, and physical dimensions. This exploratory study investigated the benefits of a 12-week online dance training intervention on mental and physical health outcomes for older women. METHODS: A convergent parallel mixed-method design was used. Forty-five older adults (74.0 ± 5.3 yrs old, 44 women) were recruited through advertisements at activity and rehabilitation centers in the North Denmark region...
May 2, 2024: BMC Geriatrics
https://read.qxmd.com/read/38696675/dual-energy-for-pulmonary-vein-isolation-using-dual-energy-focal-ablation-technology-integrated-with-a-three-dimensional-mapping-system-smartfire-3-month-results
#17
MULTICENTER STUDY
Mattias Duytschaever, Gediminas Račkauskas, Tom De Potter, Jim Hansen, Sebastian Knecht, Thomas Phlips, Johan Vijgen, Daniel Scherr, Gabor Szeplaki, Hugo Van Herendael, Mads Brix Kronborg, Benjamin Berte, Helmut Pürerfellner, Peter Lukac
AIMS: Contact force (CF)-sensing radiofrequency (RF) catheters with an ablation index have shown reproducible outcomes for the treatment of atrial fibrillation (AF) in large multicentre studies. A dual-energy (DE) focal CF catheter to deliver RF and unipolar/biphasic pulsed field ablation (PFA), integrated with a three-dimensional (3D) mapping system, can provide operators with additional flexibility. The SmartfIRE study assessed the safety and efficacy of this novel technology for the treatment of drug-refractory, symptomatic paroxysmal AF...
May 2, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38695330/incidence-and-assessment-of-delirium-following-open-cardiac-surgery-a-systematic-review-and-meta-analysis
#18
JOURNAL ARTICLE
Nadja Buch Petersson, Malene Haugaard Hansen, Jacob V B Hjelmborg, Irene Instenes, Anne Sofie Christoffersen, Katrine Lawaetz Larsen, Henrik Schmidt, Lars Peter Schødt Riber, Tone Merete Norekvål, Britt Borregaard
AIM: This systematic review and meta-analysis sought i) to provide an overview of the incidence of delirium following open cardiac surgery and ii) to investigate how incidences of delirium are associated with different assessment tools. METHODS AND RESULTS: A systematic search of studies investigating delirium following open cardiac surgery were conducted in Medline (Ovid), EMBASE, PsycINFO, CiNAHL and the Cochrane Database. Only studies with patients diagnosed or screened with a validated tool were included...
May 2, 2024: European Journal of Cardiovascular Nursing
https://read.qxmd.com/read/38695255/stable-measurement-of-chemistry-immunochemistry-and-hematology-analytes-in-a-heparin-based-anticoagulant-with-iloprost-additive-a-promising-candidate-for-the-polyvalent-blood-collection-tube
#19
JOURNAL ARTICLE
Elias Frost Wiwe, Laura Emilie Schmidt, Emilie Zeuthen, Ida Maria Storm Engelstoft, Buris Brinch Christiansen, Thomas Steen Hansen, Melanie A Burkhardt, Claus Antonio Juel Jensen
INTRODUCTION: A polyvalent blood collection tube could potentially reduce the number and volume of blood samples drawn from patients and reduce the risk of tube mix-ups in a point-of-care setting in the emergency department and the intensive care unit. METHODS: Four different concentrations of our experimental heparin anticoagulant with iloprost additive (HEP-ILOP 50 nM, 150 nM, 1000 nM, and 10 μM, respectively) were tested for significant differences and bias performance specifications against EDTA for 29 hematology analytes, and the highest concentration (HEP-ILOP 10 μM) against lithium heparin for 14 chemistry and immunochemistry analytes...
May 2, 2024: International Journal of Laboratory Hematology
https://read.qxmd.com/read/38694670/hansen-s-disease-a-practical-update-on-a-neglected-globally-significant-infection
#20
REVIEW
Soukaina Benlamkadam, Amina Errahmany, Klevor Raymond, Mohamed Chraa, Najib Kissani
Leprosy is a great mimicker. It is caused by Mycobacterium leprae and Mycobacterium lepromatosis , together termed the M. leprae complex. Leprosy can result in systemic manifestations; however, the neurocutaneous syndrome is the most classic. There is a gap in recognizing the condition leading to misdiagnosis and delays in treatment. Leprosy remains an important cause of aesthetic and functional impairment. In this paper, we provide a practical review of leprosy touching on pathophysiology, clinical manifestation, classification, diagnostic approach and management of the condition in a way that can translate into clinical practice and help physicians better identify and manage potential cases of leprosy...
April 2024: Curēus
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